Genealogical data of Boer and Nubian goats in Mexico

The pedigree file of the Boer and Nubian goat breeds in Mexico was constructed using the national database provided by the Asociación Mexicana de Criadores de Ganado Caprino de Registro. Field technicians routinely updated the goat national database by recording information from flocks participating in the performance-recording system. Information on animal identification number, parents, birth date, sex, breed, and farm of origin were used to undertake pedigree analyses using the ENDOG program (version 4.8). This paper presents a pedigree data file, tables and figures of characteristics of pedigree data, pedigree analyses, pedigree integrity, effective population size and genetic conservation index. The data can be used to estimate other population parameters, to monitor the genetic diversity of the Boer and Nubian goat breeds in Mexico, and also to design balanced breeding programs, maintaining genetic variation at reasonable levels and maximizing genetic progress in these populations.202

Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors

In recent times, a great deal of interest has been motivated on plant derived compounds known as nutraceuticals. These compounds exert important beneficial activities that improve people’s health status when are consumed regularly, and now they appear as a viable option to explore their possible therapeutic effects against diseases like cancer. Particularly, lupane-type triterpenes have shown great ability to modulate multiple cancer-related signaling pathways and processes, including NF-κB, Wnt/β-catenin, PI3K/Akt, apoptosis, and many other routes related to proliferation or cell death, which are uncontrolled in malignant tumors. These investigations have promoted in vitro and in vivo studies, searching their mechanisms of action; although more research is still needed to prove its potential in human clinical trials. This review focuses on the ability of betulin, betulinic acid and lupeol to show benefits against the most common types of malignant tumors, which are considered a major global threat for public health

Dietary patterns and diet quality during pregnancy and low birthweight: The PRINCESA cohort

Although the isolated effects of several specific nutrients have been examined, little is known about the relationship between overall maternal diet during pregnancy and fetal development and growth. This study evaluates the association between maternal diet and low birthweight (LBW) in 660 pregnant women from the Pregnancy Research on Inflammation, Nutrition,& City Environment: Systematic Analyses (PRINCESA) cohort in Mexico City. Using prior day dietary intake reported at multiple prenatal visits, diet was assessed prospectively using a priori (Maternal Diet Quality Score [MDQS]) and a posteriori (dietary patterns extracted by factor analysis) approaches. The association between maternal diet and LBW was investigated by logistic regression, controlling for confounders. Adherence to recommended guidelines (higher MDQS) was associated with a reduced risk of LBW (OR, 0.22; 95% confidence interval [0.06, 0.75], P < .05, N = 49) compared with the lowest adherence category (reference group), controlling for maternal age, education, height, marital status, pre- pregnancy body mass index, parity, energy intake, gestational weight gain, and preterm versus term birth; a posteriori dietary patterns were not associated with LBW risk. Higher adherence to MDQS was associated with a lower risk of having an LBW baby in this sample. Our results support the role of advocating a healthy overall diet, versus individual foods or nutrients, in preventing LBW.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155934/1/mcn12972_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155934/2/mcn12972.pd

Removal of heterocyclic compound carbazole using cell immobilization of thalassospira profundimaris strain M02

Cell immobilization offers promising potential to maximize microbial biodegradation activity and overcome limitations involved in bioremediation. Thalassospira profundimaris strain M02 was used to determine the effectiveness of cell immobilization for carbazole biodegradation. Effects of different matrices, effective diffusivity, mechanical strength, matrix concentration, cell mass load and reusability were investigated in this study. Results revealed that calcium alginate (Ca-Al) was better compared to gellan gum as higher carbazole biodegradation rate was observed. Diffusion analysis and mechanical strength analyses also revealed that Ca-Al possessed superior characteristics as immobilization matrix for carbazole biodegradation compared to gellan gum. Ca-Al works best at 4% (w/v) with 1.25 g of cell mass loading. In addition, immobilized strain M02 retained carbazole biodegradation activity after 6 cycles of usage

Ultrasonic evidence of an uncorrelated cluster formation temperature in manganites with first-order magnetic transition at T_C

Ultrasonic attenuation and phase velocity measurements have been carried out in the ferromagnetic perovskites La_{2/3}Ca_{1/3}MnO_3 and La_{2/3}Sr_{1/3}MnO_3. Data show that the transition at the Curie temperature, T_C, changes from first- to second-order as Sr replaces Ca in the perovskite. The compound with first-order transition shows also another transition at a temperature T* > T_C. We interpret the temperature window T_C < T < T* as a region of coexistence of a phase separated regime of metallic and insulating regions, in the line of recent theoretical proposals.Comment: 4 pages, 2 figure

The role of neo-tectonics in the sedimentary infilling and geomorphological evolution of the Guadalquivir estuary (Gulf of Cadiz, SW Spain) during the Holocene.

Spain) has yielded new evidence regarding the sedimentary infilling and geomorphological evolution of the Guadalquivir estuary during the Holocene. The sedimentation and geomorphological disposition have been strongly conditioned by neotectonic activity along a set of SW-NE alignments, interrupted by other alignments that follow E-W and NW-SE directions. The most conspicuous of the SW-NE alignments is the Torre Carbonero-Marilópez Fault (TCMF). South of this fault, the estuary experienced a marked subsidence from about 4000 to 2000 cal. yr BP through a series of sedimentary sequences of retrogradation and aggradationwithin the context of relative sea-level rise. From c. 2000 cal. yr BP to the present the subsidence has remained relatively dormant, with progradation of the littoral systems and infilling of the marshland progressing within a context of sea-level stability. Our results reveal that neotectonic activity is a critical factor thatmust also be reckonedwith in any attempt to understand the Holocene geomorphological evolution in the Guadalquivir estuary

Metastable liquid lamellar structures in binary and ternary mixtures of Lennard-Jones fluids

We have carried out extensive equilibrium molecular dynamics (MD) simulations to investigate the Liquid-Vapor coexistence in partially miscible binary and ternary mixtures of Lennard-Jones (LJ) fluids. We have studied in detail the time evolution of the density profiles and the interfacial properties in a temperature region of the phase diagram where the condensed phase is demixed. The composition of the mixtures are fixed, 50% for the binary mixture and 33.33% for the ternary mixture. The results of the simulations clearly indicate that in the range of temperatures $78 < T < 102 ^{\rm o}$K, --in the scale of argon-- the system evolves towards a metastable alternated liquid-liquid lamellar state in coexistence with its vapor phase. These states can be achieved if the initial configuration is fully disordered, that is, when the particles of the fluids are randomly placed on the sites of an FCC crystal or the system is completely mixed. As temperature decreases these states become very well defined and more stables in time. We find that below $90 ^{\rm o}$K, the alternated liquid-liquid lamellar state remains alive for 80 ns, in the scale of argon, the longest simulation we have carried out. Nonetheless, we believe that in this temperature region these states will be alive for even much longer times.Comment: 18 Latex-RevTex pages including 12 encapsulated postscript figures. Figures with better resolution available upon request. Accepted for publication in Phys. Rev. E Dec. 1st issu

Kinetic studies of marine psychrotolerant microorganisms capable of degrading diesel inthe presence of heavy metals

The presence of heavy metals in Antarctica is an emerging issue as human influence becomes more discernible over the years.The study of pollution in Antarctica can help people to understand the real influence of human activities on the environmental pollution from polar regions. Bioremediation of petroleum hydrocarbons in the polar environment where toxic metals co-existed involves selecting strictly auto chthonous Antarctic strains with dual catabolic competence and tolerance to toxic metals. In this study, diesel degradation was observed in the presence of 1 ppm of eight selected heavy metals; Ag, Al, Cd, Co, Cr, Hg, Ni and Zn. Bacterial growth was inhibited in increasing order of Zn>Cr>Cd>Al>Ni>Hg>Co>Ag. Bacterial growth was the highest in Zn at OD 6000.556 (P>0.05) and lowest in Ag at OD 6000.151 (PNi>Cd>Ag>Zn>Al>Cr>Hg, which was analysed using gravimetry analysis. Degradation was the highest in Hg at 52.23%(P>0.05) and lowest in Co at 22.76% (P<0.05). This work serves as a pilot study in gathering data to analyse and gather moredata for inhibition concentration of heavy metals for the Antarctic marine bacteria

Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled Analysis of Case‐Control Studies of the Stop Consortium

Background: Inconsistent findings have been reported regarding the relationship between dietary iron intake and the risk of gastric cancer (GC). Methods: We pooled data from 11 case‐control studies from the Stomach Cancer Pooling (StoP) Project. Total dietary iron intake was derived from food frequency questionnaires combined with national nutritional tables. We derived the odds ratios (ORs) and 95% confidence intervals (CIs) for quartiles of dietary iron through multivariable unconditional logistic regression models. Secondary analyses stratified by sex, smoking status, caloric intake, anatomical subsite and histological type were performed. Results: Among 4658 cases and 12247 controls, dietary iron intake was inversely associated with GC (per quartile OR 0.88; 95% CI: 0.83–0.93). Results were similar between cardia (OR = 0.85, 95% CI = 0.77–0.94) and non‐cardia GC (OR = 0.87, 95% CI = 0.81–0.94), and for diffuse (OR = 0.79, 95% CI = 0.69–0.89) and intestinal type (OR = 0.88, 95% CI = 0.79–0.98). Iron intake exerted an independent effect from that of smoking and salt intake. Additional adjustment by meat and fruit/vegetable intake did not alter the results. Conclusions: Dietary iron is inversely related to GC, with no difference by subsite or histological type. While the results should be interpreted with caution, they provide evidence against a direct effect of iron in gastric carcinogenesis. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.This study was supported by the Fondazione AIRC per la Ricerca sul Cancro, Project no. 21378 (Investigator Grant). The Unidade de Investigação em Epidemiologia—Instituto de Saúde Pública da Universidade do Porto (EPIUnit; UIDB/04750/2020) and the Laboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR; LA/P/0064/2020) were funded by the Foundation for Science and Technology—FCT (Portuguese Ministry of Science, Technology and Higher Education). SM was supported by the project “NEON‐PC—Neuro‐oncological complications of prostate cancer: longitudinal study of cognitive decline” (POCI‐01‐0145‐FEDER‐032358; ref. PTDC/SAU‐EPI/32358/2017), which is funded by FEDER through the Operational Programme competitiveness and Internationalization, and national funding from FCT and the EPIUnit—Junior Research—Prog Financing (UIDP/04750/2020). The authors thank the European Cancer Prevention (ECP) Organization for providing support for the StoP Project meetings and all MCC‐Spain study collaborators (CIBERESP, ISCIII, ISGlobal, ICO, University of Huelva, University of Oviedo, University of Cantabria, ibs.Granada, Instituto Salud Pública de Navarra, FISABIO, Murcia Regional Health Authority and cols)