VHDL Implementation of Fastest Braun’s Multiplier

Multiplication is an essential arithmetic operation for common Digital Signal Processing (DSP) applications, such as filtering and Fast Fourier Transform (FFT). To achieve high execution speed, parallel array multipliers are widely used. To decrease computational delay and improve resource utilization carry look-ahead adder circuit are use and Braun’s-architectures multiplier is compared with its conventional architectural. DOI: 10.17762/ijritcc2321-8169.15057

Stability constants of some lanthanide mixed ligand complexes

722-725Stability constants of the mixed ligand complexes of some lanthanides, viz., La(III), Pr(III), Nd(III), Gd(III) and Dy(III) with oxydiacetic acid (ODA), tartaric acid (TRA), malic acid (MEA), iminodiacetic acid (IDA) and glycine (GLY) as ligands have been determined pH-metrically at 25 ± 1°C and at an ionic strength of 0.1mol dm-3 (KNO3). A comparison of the values of stability constants of the complexes reveals the order, La(III) K values are negative for all the ternary and quaternary systems; however, DD log K values are significantly positive. These have been explained in terms of intramolecular hydrophobic ligand-ligand interactions. The stability constant data have been used to study the electrostatic factors involved in the formation of these mixed complexes

Medical Negligence: A Conceptual Analysis

The concept of medical negligence refers to the malpractice of a medical professional who fails to meet the standards of his/her profession, which results in the death of a patient who was expecting the medical professional to save her/her life. Medical negligence is the most shameful act a medical professional can conduct because this negligence most of the time results in the death of the patient. The concept of medical negligence is well established in India however the Indian judiciary still follows Bolam‟s test which is outdated and vague and therefore new methods to determine medical negligence must be adopted by the Indian judiciary. To deliver justice in cases of medical negligence, the Indian judiciary must adopt new approaches so that at least the sufferings of a person in courts can be prevented. The court must award heavy punishments for those found guilty of medical negligence and impose heavy fines on hospitals that have employed such negligent professionals

Dysphagia due to necrotizing otitis externa

An 88-year-old man presented with delirium, and subsequently developed hoarseness and oropharyngeal dysphagia. This was due to skull-based osteomyelitis from necrotizing otitis externa (NOE), causing lower cranial nerve (X, XII) palsies and venous sinus thrombosis. Diagnosis was delayed as the patient reported no otalgia, had an almost normal looking external auditory canal and was not diabetic. He deteriorated and died despite intravenous antibiotics. We need a high index of suspicion for NOE and its complications in patients presenting with otolaryngeal symptoms

Development of Nano SiO2 Particles Dispersed Shape Memory Epoxy Composites

Thermo responsive shape memory epoxy based composites are being investigated for their excellent mechanical and thermal properties. In present study the thermosetting epoxy containing different composition of SiO2 nano particles ranging from 1 to 4 wt. % have been prepared through solvent casting route. Developed composites have been studied for grain analysis, FTIR, shape recovery, impact strength and hardness. Addition of 3 wt. % SiO2 improves hardness and impact strength significantly. Average grain size of SiO2 particles increase at higher wt. % of SiO2 in polymer matrix due to agglomeration of nanoparticles

Carbapenem resistance in Escherichia coli and Klebsiella pneumoniae among Indian and international patients in North India

The aim of the study was to find out the carbapenem resistance rate and prevalence of different carbapenemase genes in Klebsiella pneumoniae and Escherichia coli from a North Indian corporate hospital that receives both Indian and international patients. A total of 528 clinical isolates of E. coli and K. pneumoniae were included in the study. All isolates that were found resistant to carbapenems by MIC testing (Vitek II Compact®) were screened for NDM, OXA-48, VIM, and KPC genes by PCR. Sequencing of NDM gene and transmissibility by conjugation assay were checked on 22 randomly selected NDM-positive isolates. One hundred and fifty-six isolates (29.54%) were carbapenem-resistant. The rate of carbapenem resistance was significantly higher in K. pneumoniae as compared to E. coli (53.9% vs. 15.6%; p < 0.05). The NDM gene was found in 34.6% (54/156), OXA-48 in 31.4% (49/156), co-expression of NDM + OXA-48 in 15.3% (24/156) of the carbapenem-resistant isolates. VIM and KPC were absent in all isolates. NDM gene was significantly more prevalent in E. coli than K. pneumoniae (p < 0.05). All the tested isolates formed transconjugants and NDM-5 was the most common variant in both species (15/22). The presence of plasmid-based NDM calls for stricter surveillance measures in our hospital settings

In vivo effects of traditional ayurvedic formulations in Drosophila melanogaster model relate with therapeutic applications

Background: Ayurveda represents the traditional medicine system of India. Since mechanistic details of therapy in terms of current biology are not available in Ayurvedic literature, modern scientific studies are necessary to understand its major concepts and procedures. It is necessary to examine effects of the whole Ayurvedic formulations rather than their “active” components as is done in most current studies. Methods: We tested two different categories of formulations, a Rasayana (Amalaki Rasayana or AR, an herbal derivative) and a Bhasma (Rasa-Sindoor or RS, an organo-metallic derivative of mercury), for effects on longevity, development, fecundity, stress-tolerance, and heterogeneous nuclear ribonucleoprotein (hnRNP) levels of Drosophila melanogaster using at least 200 larvae or flies for each assay. Results: A 0.5% (weight/volume) supplement of AR or RS affected life-history and other physiological traits in distinct ways. While the size of salivary glands, hnRNP levels in larval tissues, and thermotolerance of larvae/adult flies improved significantly following feeding either of the two formulations, the median life span and starvation resistance improved only with AR. Feeding on AR or RS supplemented food improved fecundity differently. Feeding of larvae and adults with AR increased the fecundity while the same with RS had opposite effect. On the contrary, feeding larvae on normal food and adults on AR supplement had no effect on fecundity but a comparable regime of feeding on RS-supplemented food improved fecundity. RS feeding did not cause heavy metal toxicity. Conclusions: The present study with two Ayurvedic formulations reveals formulation-specific effects on several parameters of the fly's life, which seem to generally agree with their recommended human usages in Ayurvedic practices. Thus, Drosophila, with its very rich genetic tools and well-worked-out developmental pathways promises to be a very good model for examining the cellular and molecular bases of the effects of different Ayurvedic formulations