Capturing human activity spaces: New geometries

Activity space, defined as “the local areas within which people move or travel during the course of their activities during a specified time period”, is a measure of an individual’s spatial behavior which captures individual and environmental differences and offers an alternative approach to studying the spatial reach of travelers. The shape and area of activity space is a product of how it is conceptualized and measured. This paper enlarges the set of geometries which can be used to describe activity space. It tests four parametric geometries (ellipse, superellipse, Cassini oval, and bean curve), which are identified as those capturing a specific share of all locations visited, i.e. 95%, while minimizing the area covered. They are estimated for a number of long-duration data sets while distinguishing between trip purposes. We present both a flexible, easily adaptable method for calculating activity spaces of different shapes and a qualitative comparison of the four above-mentioned shape types on the basis of the given surveys. We can thus demonstrate that the choice of an appropriate shape representing an individual’s activity space is highly dependent on the spatial distributions and frequencies of the locations visited by the person in the given time period

Traditional artifacts from dried leaves of Cymbidium species (orchidaceae) in Indian state of Sikkim

390-394Sikkim is one of the most beautiful tourist hill states with tremendous biodiversity wealth. Cymbidium orchid dominates the states for hobby gardeners and commercial cultivating farmers. Handicraft is a part of hobbies and livelihood of the indigenous communities of the region. The Lepcha tribe craftsmen based on dried leaves of Cymbidium orchid is becoming promising apart from their handloom, cane and bamboo products. Attractive, simple products of dried Cymbidium leaves such as fruit and vegetable baskets, containers, sitting mats, hanging pots, trash bins, and plant growing pots is gaining popularity. Due to no noticeable researches and development in this sector, the traditional artifact craftsmen are unable to establish as a source of livelihood. With strategic approaches and intervention, these unique traditional craftsmen would be a reliable economic venture for the rural youth

Does BCR/ABL1 positive Acute Myeloid Leukaemia Exist?

The BCR/ABL1 fusion gene, usually carried by the Philadelphia chromosome (Ph) resulting from t(9;22)(q34;q11) or variants, is pathognomonic for chronic myeloid leukaemia (CML). It is also occasionally found in acute lymphoblastic leukaemia (ALL) mostly in adults and rarely in de novo acute myeloid leukaemia (AML). Array Comparative Genomic Hybridization (aCGH) was used to study six Ph(+)AML, three bi-lineage and four Ph(+)ALL searching for specific genomic profiles. Surprisingly, loss of the IKZF1 and/or CDKN2A genes, the hallmark of Ph(+)ALL, were recurrent findings in Ph(+)AML and accompanied cryptic deletions within the immunoglobulin and T cell receptor genes. The latter two losses have been shown to be part of 'hot spot' genome imbalances associated with BCR/ABL1 positive pre-B lymphoid phenotype in CML and Ph(+)ALL. We applied Significance Analysis of Microarrays (SAM) to data from the 'hot spot' regions to the Ph(+)AML and a further 40 BCR/ABL1(+) samples looking for differentiating features. After exclusion of the most dominant markers, SAM identified aberrations unique to de novo Ph(+)AML that involved relevant genes. While the biological and clinical significance of this specific genome signature remains to be uncovered, the unique loss within the immunoglobulin genes provides a simple test to enable the differentiation of clinically similar de novo Ph(+) AML and myeloid blast crisis of CML. © 2013 John Wiley & Sons Ltd and Crown

The effect of long term combined yoga practice on the basal metabolic rate of healthy adults

BACKGROUND: Different procedures practiced in yoga have stimulatory or inhibitory effects on the basal metabolic rate when studied acutely. In daily life however, these procedures are usually practiced in combination. The purpose of the present study was to investigate the net change in the basal metabolic rate (BMR) of individuals actively engaging in a combination of yoga practices (asana or yogic postures, meditation and pranayama or breathing exercises) for a minimum period of six months, at a residential yoga education and research center at Bangalore. METHODS: The measured BMR of individuals practicing yoga through a combination of practices was compared with that of control subjects who did not practice yoga but led similar lifestyles. RESULTS: The BMR of the yoga practitioners was significantly lower than that of the non-yoga group, and was lower by about 13 % when adjusted for body weight (P < 0.001). This difference persisted when the groups were stratified by gender; however, the difference in BMR adjusted for body weight was greater in women than men (about 8 and 18% respectively). In addition, the mean BMR of the yoga group was significantly lower than their predicted values, while the mean BMR of non-yoga group was comparable with their predicted values derived from 1985 WHO/FAO/UNU predictive equations. CONCLUSION: This study shows that there is a significantly reduced BMR, probably linked to reduced arousal, with the long term practice of yoga using a combination of stimulatory and inhibitory yogic practices

Value Creation from Big Data: Looking Inside the Black Box

The advent of big data is fundamentally changing the business landscape. We open the ‘black box’ of the firm to explore how firms transform big data in order to create value and why firms differ in their abilities to create value from big data. Grounded in detailed evidence from China, the world’s largest digital market, where many firms actively engage in value creation activities from big data, we identify several novel features. We find that it is not the data itself, or individual data scientists, that generate value creation opportunities. Rather, value creation occurs through the process of data management, where managers are able to democratize, contextualize, experiment and execute data insights in a timely manner. We add richness to current theory by developing a conceptual framework of value creation from big data. We also identify avenues for future research and implications for practicing managers