135 research outputs found

    Human Robot Interaction and Usability Studies for a Smart Wheelchair

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    We build on previous work [12], [14] on the development of a computer controlled wheelchair equipped with a suite of sensors and a novel interface for human-robot interaction. In this paper, we present experimental results and usability studies for the wheelchair. The architecture for human-robot interaction is hierarchical, with the lowest level corresponding to trajectory control, the intermediate level being behavioral and the highest level involving the composition of behaviors and navigation. Our experimental results illustrate the benefits of a shared-control paradigm where the human operator selects the appropriate hehavior(s) or goals while the software is responsible for executing behaviors and generating safe trajectories. Experiments with human users highlight advantages of augmentation in wheelchairs

    Revolutionizing physics: a comprehensive survey of machine learning applications

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    In the context of the 21st century and the fourth industrial revolution, the substantial proliferation of data has established it as a valuable resource, fostering enhanced computational capabilities across scientific disciplines, including physics. The integration of Machine Learning stands as a prominent solution to unravel the intricacies inherent to scientific data. While diverse machine learning algorithms find utility in various branches of physics, there exists a need for a systematic framework for the application of Machine Learning to the field. This review offers a comprehensive exploration of the fundamental principles and algorithms of Machine Learning, with a focus on their implementation within distinct domains of physics. The review delves into the contemporary trends of Machine Learning application in condensed matter physics, biophysics, astrophysics, material science, and addresses emerging challenges. The potential for Machine Learning to revolutionize the comprehension of intricate physical phenomena is underscored. Nevertheless, persisting challenges in the form of more efficient and precise algorithm development are acknowledged within this review

    The Taming of Closed Time-like Curves

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    We consider a R1,d/Z2R^{1,d}/Z_2 orbifold, where Z2Z_2 acts by time and space reversal, also known as the embedding space of the elliptic de Sitter space. The background has two potentially dangerous problems: time-nonorientability and the existence of closed time-like curves. We first show that closed causal curves disappear after a proper definition of the time function. We then consider the one-loop vacuum expectation value of the stress tensor. A naive QFT analysis yields a divergent result. We then analyze the stress tensor in bosonic string theory, and find the same result as if the target space would be just the Minkowski space R1,dR^{1,d}, suggesting a zero result for the superstring. This leads us to propose a proper reformulation of QFT, and recalculate the stress tensor. We find almost the same result as in Minkowski space, except for a potential divergence at the initial time slice of the orbifold, analogous to a spacelike Big Bang singularity. Finally, we argue that it is possible to define local S-matrices, even if the spacetime is globally time-nonorientable.Comment: 37 pages, LaTeX2e, uses amssymb, amsmath and epsf macros, 8 eps and 3 ps figures; (v2): Two additional comments + one reference added; (v3): corrections in discussion of CTCs + some clarification

    Renal Medullary Carcinoma: Case Report of an Aggressive Malignancy with Near-Complete Response to Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin Chemotherapy

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    Renal medullary carcinoma (RMC) is a rare but aggressive malignancy affecting young individuals with sickle cell trait. Renal medullary carcinoma commonly presents with advanced or metastatic disease and is associated with a rapidly progressive clinical course and an extremely short overall survival measured in weeks to few months. Due to the rarity of RMC, there is no proven effective therapy and patients are often treated with platinum-based chemotherapy. We report near-complete radiological and pathological response in a patient treated with dose-dense MVAC (methotrexate, vinblastine, doxorubicin, and cisplatin) chemotherapy. The patient underwent consolidation nephrectomy and retroperitoneal lymph node dissection and had a 16-month progression-free survival, one of the longest reported in patients with RMC
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