Kondenzirani pirimidini. II dio: Sinteza i antimikrobna aktivnost nekih furo[3,2-e]imidazo[1,2-c]pirimidina i furo[2,3-d]pirimidina

2-Amino-4,5-diphenylfuran-3-carbonitrile (2) reacted with N-[bis(methylthio)methylene]glycine ethyl ester (1) to afford a double cyclized product 5-methylthio-8,9-diphenylfuro[3,2-e]imidazo [1,2-c]pyrimidin-2(3H)-one (3). Compound 2 also reacts with benzonitrile to give 4-amino- 2,5,6-triphenylfuro[2,3-d]pyrimidine (4). Treatment of 2 with HCONH2, under reflux, afforded 4-amino-5,6-diphenylfuro[2,3-d]pyrimidine (5) which was then allowed to react with chloroacetaldehyde to give 8,9-diphenylfuro[3,2-e]imidazo[1,2-c]pyrimidine (6). Reaction of 2 with HCOOH gave 5,6-diphenylfuro[2,3-d]pyrimidin-4(3H)-one (7) which was then converted to its tosyl derivative (8). The antimicrobial activity of the synthesized compounds 2–8 was tested.2-Amino-4,5-difenilfuran-3-karbonitril (2) u reakciji s etilnim esterom N-[bis(metiltio)metilen]glicina (1) daje produkt dvostruke ciklizacije – 5-metiltio-8,9-difenilfuro[3,2-e]imidazol[1,2-c]pirimidin-2(3H)-on (3). Također, u reakciji s benzonitrilom spoj 2 daje 4-amino-2,5,6-trifenilfuro[2,3-d]pirimidin (4). Grijanjem spoja 2 s HCONH2 dobiven je 4-amino-5,6-difenilfuro[2,3-d]pirimidin (5), koji reakcijom s kloracetaldehidom daje 8,9- difenilfuro[2,3-d]imidazo[1,2-c]pirimidin (6). Reakcijom 2 s HCOOH dobiven je 5,6-difenilfuro[2,3-d]pirimidin- 4(3H)-on (7), koji je preveden u tozilat (8). Spojevima 2-8 ispitana je antimikrobna aktivnost

L-CAQ: Joint link-oriented channel-availability and channel-quality based channel selection for mobile cognitive radio networks

Channel availability probability (CAP) and channel quality (CQ) are two key metrics that can be used to efficiently design a channel selection strategy in cognitive radio networks. For static scenarios, i.e., where all the users are immobile, the CAP metric depends only on the primary users' activity whereas the CQ metric remains relatively constant. In contrast, for mobile scenarios, the values of both metrics fluctuate not only with time (time-variant) but also over different links between users (link-variant) due to the dynamic variation of primary- and secondary-users' relative positions. As an attempt to address this dynamic fluctuation, this paper proposes L-CAQ: a link-oriented channel-availability and channel-quality based channel selection strategy that aims to maximize the link throughput. The L-CAQ scheme considers accurate estimation of the aforementioned two channel selection metrics, which are governed by the mobility-induced non-stationary network topology, and endeavors to select a channel that jointly maximizes the CAP and CQ. The benefits of the proposed scheme are demonstrated through numerical simulation for mobile cognitive radio networks

Structural coloration of chitosan-cationized cotton fabric using photonic crystals

Conventional textile coloration is a wet process involving high levels of water and chemicals consumption and wastewater generation. However, colour in textiles can also be generated by other mechanisms such as: absorption, emission, diffraction, interference and photochromism.[1] Chromotropic effect refers to reversible colour transformation due to external chemical or physical influence.[2] Photonic crystals are an important class of chromotropic materials. Colloidal crystals with a periodicity on the scale of half the wavelength of visible light exhibit structural colours similar to natural opals due to a diffraction effects that result in the appearance of a photonic band gap that forbids propagation of certain wavelengths.[3] Structural colouration is emerging as an innovative technology to produce colourful textiles materials.[4] Various colours impossible to reproduce by chemical coloration can be created by modifying the periodicity of the nanostructures or the environmental conditions using a single material.[5, 6] Photonic crystals can be applied on textile fabrics by colloid self-assembly and the structural colours can be controlled by adjusting the microspheres size and the viewing angles.[7] However, their application for textile structural coloration has been barely reported.[8] In this work, P(St-MMA-AA) composite nanospheres were deposited onto chitosan-cationized woven cotton fabrics. The structural colours of the deposited photonic crystals on the fabrics and its washing fastness were investigated.info:eu-repo/semantics/publishedVersio

Effect of phosphorus, molybdenum and rhizobium inoculation on yield and yield attributes of mungbean

An experiment was conducted during kharif season, 2005 at Soil Science Division, Bangladesh Agricultural Research Institute to study the effect of phosphorus (P), molybdenum (Mo) and Rhizobium inoculation on the yield and yield contributing characters of mungbean (Vigna radiata) on a silty clay loam soil. The experiment was laid out in RCBD with four replications. Ten treatments were formulated with the combination of 4 levels of P (0, 20, 40, 60 kg/ha) and 2 levels of Mo (1.0, 1.5 kg/ha) having a common Rhizobium inoculant. P and Mo application at the rate of 40 and 1.0 kg/ha respectively, significantly increased yield and yield contributing characters of mungbean compared to uninoculated and control. Highest stover (26.67 g/plant) and grain yield (14.61 g/plant) were obtained with P (40 kg/ha), Mo (1.0 kg/ha) and Rhizobium inoculation. Above these levels of P and Mo decreased yield and yield contributing characters. Dry weight of plant tops, seed yield/plant and yield-contributing characters were positively correlated with the number of nodules/plant. Combined application of Rhizobium inoculant along with 40 kg P and 1.0 kg Mo/ha was considered to be the suitable combination of fertilizer for mungbean cultivation in silty clay loam soils

Validated Molecular Marker for Downy Mildew Disease Resistance Breeding of Sunflower: A Short Review

The oomycete pathogen Plasmopara halstedii responsible for sunflower downy mildew (DM), that is a significant and important disease that greatly affects the economy. As of now, there is no non-race-specific resistance for this disease and breeders are depended on race-specific resistance to control DM disease. On the other hand, using conventional breeding procedure introgression of the DM resistance genes is a long-term task due to the highly virulent and aggressive nature of the P. halstedii pathogen. Molecular markers that can be applied at the seedling stage, offers rapid response for selection with higher precision as well as a lower cost. There are currently 36 downy mildew resistance genes (R genes), designated as Pl (Pl1-Pl36, Plhra, and PlArg, in sunflowers, each with a unique linkage group (LGs). The availability of DM resistance genomic data of sunflower, related to Single Nucleotide Polymorphisms (SNP) based markers with mine allelic diversity maximize the opportunity of utilizing Marker assisted selection (MAS) techniques for downy mildew resistance breeding. This review highlights the available genetic marker and their utilization at MAS techniques for enhancing downy mildew disease resistant breeding program of sunflowers

Effect of long term fertilization on soil respiration and enzyme activities in floodplain soil

In agricultural farming system organic manuring and inorganic fertilizer application are the most common agricultural practices. Different fertilizer application lead to differences in soil nutrients, pH, and microbial species, which in turn affect the transformation and decomposition of organic carbon by soil microorganisms. Therefore, a laboratory incubation study was carried out to investigate the influence of long term manuring and fertilization on soil respiration by means of C mineralization and enzyme activities. A parallel first- and zero-order kinetic model was used to describe observed C mineralization in soil. The annual carbon mineralization was found to be significantly influenced by different fertilizer. This result indicates that more stable organic matter was formed in NP treated soil which is less prone to decomposition if present crop management has been changed. Other ward, NP has the highest potentiality to soil for the purpose of carbon sequestration in floodplain soil compared to other fertilizer. Urease activities varied from 4.7µg NH4-N/g soil/2h in NK treatment to 25.7µg NH4-N/g soil/2h in N+FYM treatment. N treatment had a significantly higher urease activity compared to the respective controls. When P, K, S and PK applied separately with N then the treatments show low enzyme activity to control and other treatments (N, N+FYM and NPKSZn). There were no significant differences for Arylamidase activities among the treatments. The arylamidase activities decreased when S applied in combination with N. On the other hand arylamidase activity increased with the application of all other treatment

Impact of land cover changes on land surface temperature and human thermal comfort in Dhaka City of Bangladesh

Urbanization leads to the construction of various urban infrastructures in the city area for residency, transportation, industry, and other purposes, which causes major land use change. Consequently, it substantially affects Land Surface Temperature (LST) by unbalancing the surface energy budget. Higher LST in city areas decreases human thermal comfort for the city dwellers and affects the urban environment and ecosystem. Therefore, a comprehensive investigation is needed to evaluate the impact of land use change on the LST. Remote Sensing (RS) and Geographic Information System (GIS) techniques were used for the detailed investigation. RS data for the years 1993, 2007 and 2020 during summer (March–May) in Dhaka city were used to prepare land cover maps, analyze LST, generate hazard maps and relate the land cover change with LST by using GIS. The results show that the built-up area in Dhaka city increased by 67% from 1993 to 2020 by replacing lowland mainly, followed by vegetation, bare soil and water bodies. LSTs found in the study area were ranged from 23.26 to 39.94 °C, 23.69 to 43.35 °C and 24.44 to 44.58 °C for the years 1993, 2007 and 2020, respectively. The increases of spatially distributed maximum and mean LST were found 4.62 °C and 6.43 °C, respectively, for the study period of 27 years while the change in minimum LST was not substantial. LST increased by around 0.24 °C per year and human thermal discomfort shifted from moderate to strong heat stress for the total study period due to the increase of built-up and bare lands. This study also shows that normalized difference vegetation index (NDVI) and normalized difference water index (NDWI) were negatively correlated with LST while normalized difference built-up Index (NDBI) and normalized difference built-up Index (NDBAI) were positively correlated with LST. The methodology developed in this study can be adapted to other cities around the globe

Emphysematous pyelonephritis

Emphysematous pyelonephritis is an acute necrotizing infection of the renal parenchyma, prompt diagnosis and early treatment is crucial because of the high rate of mortality. We report a case of a 55-year-old female patient with ten-year history of diabetes mellitus presented with pain in right flank, fever and malaise. She was diagnosed as a case of emphyse­matous pyelonephritis, and was successfully treated in our department. The case is presented along with a literature review

Trends in Seagrass Research and Conservation in Malaysian Waters

The seagrass ecosystems found in the marine and coastal areas, with substantial economic and ecological services and span all over the globe excluding the Antarctic region. The Coral Triangle and Southeast Asia are recognized as a worldwide hotspot of seagrass species and habitats, encompassing 10-21 species of seagrass in every nation, although the study, understanding, and quantity of publications on seagrass ecosystems are rather limited in the region, including Malaysia. Malaysia contains 18 seagrass species from three families, which occupy 16.8 km2 of coastal area, where the study and discovery of seagrass species and meadows began in 1904 with the report of Beccari. All of the published papers reviewed reported on Malaysian seagrass-related research, which was divided into nine topic groups: biology and distribution, carbon sequestration, fauna, remote sensing, impact and pollution genetic study, restoration, microbiological investigation, and others. The extensive study of the seagrass ecosystem began in 1993, and we have identified 183 published papers from Scopus, 141 publications from Web of Science, and 42 from Google Scholar. However, the average trend of the number of publications from 1993 to 1999 was 0.71 ± 0.36, while from 2000 to 2022 was 7.70 ± 1.16 followed by the average trend of the yearly number of publications was 6.78 ± 1.08. The highest number of publications was found on faunal categories (43.17%), followed by biology and distribution (21.85%). The number of articles that were published on Malaysian seagrass meadows each year has been discovered to be rising, which indicates that the trends in seagrass study and publishing were progressively garnering the attention of researchers, academics, and the government. However, to better understand the sustainable ecology and ecosystem services provided by seagrass habitats, an emphasis on certain research niches, such as the genetic study of flora and fauna in seagrass meadows, microbial ecology, and restoration as well as conservation of seagrass species might be helpful.22 página

ANCA-negative Churg-Strauss Syndrome

A rare and a disease of unknown etiology, Churg-Strauss syndrome (CSS) is a granulomatous necrotizing small vessel vasculitis characterized by the presence of asthma, sinusitis, and hypereosinophilia, which is initially described by Churg and Strauss in 1951. Because of its clinical and pathological features that overlap with those of the other anti-neutrophil antibody (ANCA)-associated systemic vasculitides (AASVs) and now the disease is classified as AASVs. The ANCA status may dictate the clinical phenotype. ANCA-positive patients are significantly more likely to have disease manifesta­tions associated with small-vessel vasculitis, including oecrotising glomemlonephritis, mononeuritis and purpura, whereas ANCA-negative cases predominantly likely to have cardiac and lung involvement. The objective of this case report is to point out the possibility of vasculitic rash in ANCA-negative CSS in a 35-year-old man and the disease rarely occurs in Bangladeshi population. We analyze the history, clinical examinations and relevant investigations related to the patient to establish the diagnosis in our department. The clinical scenario and biopsy help us to attain the diagnosis. But due to unavailability of patients' cohort we have limitations of comparison of ANCA status in Bangladeshi populations. Though ANCA-positive and ANCA-negative CSS differ phenotypically, primary therapy for both the conditions is systemic glucocorticoids. Additional immunosuppressive agents like cyclophosphamide, mycophenolate mofetil, azathioprine, rituxin1ab are occasionally added in patients with more advanced or refractory disease