Stage reduced counter-rotating axial compressor for jet engine

Variation in the states of system, mass flow and pressure are some of the disturbances which are experienced by the compressors in the jet engine under working condition. One of the main factors that influence the efficiency of a jet engine is the pressure ratio. In order to achieve the required pressure ratio, we should have relatively a greater number of stages in the compressor that leads to an increase in the weight of the engine. The stator and rotor are the essential parts of an aircraft's axial compressor. CFD is used in order to evaluate the pressure ratio. In this paper, we are going to analyze a three-stage compressor instead of an actual six-stage compressor. The mass flow rate inside the control system can be used to maintain the stability of the system. Compressor weight and pressure ratio at each stage can be reduced if we have a clockwise and anti-clockwise rotating rotor. With the use of a universal gear system, the two clockwise rotors and one anti-clockwise rotor were analyzed. The main outlook of this work is to show the maximum pressure ratio of the compressor at the outlet with our desired configurations. In conclusion, it was shown that the weight of the aircraft engine can be effectively reduced

Stage reduced counter-rotating axial compressor for jet engine

Variation in the states of system, mass flow and pressure are some of the disturbances which are experienced by the compressors in the jet engine under working condition. One of the main factors that influence the efficiency of a jet engine is the pressure ratio. In order to achieve the required pressure ratio, we should have relatively a greater number of stages in the compressor that leads to an increase in the weight of the engine. The stator and rotor are the essential parts of an aircraft's axial compressor. CFD is used in order to evaluate the pressure ratio. In this paper, we are going to analyze a three-stage compressor instead of an actual six-stage compressor. The mass flow rate inside the control system can be used to maintain the stability of the system. Compressor weight and pressure ratio at each stage can be reduced if we have a clockwise and anti-clockwise rotating rotor. With the use of a universal gear system, the two clockwise rotors and one anti-clockwise rotor were analyzed. The main outlook of this work is to show the maximum pressure ratio of the compressor at the outlet with our desired configurations. In conclusion, it was shown that the weight of the aircraft engine can be effectively reduced

Design and development of Metformin hydrochloride Trilayered sustained release tablets

Diabetes is one of the major causes of death and disability in the world. Diabetes results from decreased secretion of insulin, decreased insulin action or both. The main aims of the investigation was to design and development of trilayer floating tablets of metformin hydrochloride and also study the influence of concentrations of HPMCK 100 on various properties of tablet and tri-layer tablets were formulated by wet granulation method. Drug- excipient compatibility studies were conducted by FTIR spectroscopy. The prepared granules, tablets were evaluated. In-vitro release data revealed that F5 formulation sustained the release for 12 hours and the release data was fitted into zero order, first order, Higuchi and Peppas equations. The drug release from the formulation followed zero kinetics and exhibits Peppas mechanism. Release exponents ‘n ’ was found less than 0.85 indicating the release governed by non-fickian anomalous transport mechanism. Key words: Tri ilayer floating tablets, Hydroxy propyl methyl cellulose (HPMCK100

Study of the influence of Hydrophillic polymers and Citric acid on Bi-layered floating tablets of Diltiazem hydrochloride

In the present study an attempt was made to study the effect of formulation variables on bilayered floating tablet of Diltiazem hydrochloride. Immediate release layer was formulated by using various super disintegrants such as sodium starch glycolate, cross carmellose sodium, crospovidone and sustained release layer was formulated with different grades of hydrophilic polymers like HPMCK4M, HPMCE5 and HPMCK100M by wet granulation method. The influence of polymer and citric acid concentrations were also investigated. The prepared tablets were characterized and rate of drug release from an immediate release layer was 99.9 % were found at the end of 20 minutes followed by sustained the drug release for 12hrs from sustained release layer. The dissolution data were fitted into zero order, first order, Higuchi and Peppas equations. Results revealed that the drug release from the formulation F20 followed zero order kinetics and exhibited Peppas transport mechanism. Key words: Diltiazem hydrochloride, wet granulation method, first order kinetics, HPMC-Hydroxy propyl methylcellulose