1,415 research outputs found
Effects of Quasi-Static Aberrations in Faint Companion Searches
We present the first results obtained at CFHT with the TRIDENT infrared
camera, dedicated to the detection of faint companions close to bright nearby
stars. The camera's main feature is the acquisition of three simultaneous
images in three wavelengths (simultaneous differential imaging) across the
methane absorption bandhead at 1.6 micron, that enables a precise subtraction
of the primary star PSF while keeping the companion signal. The main limitation
is non-common path aberrations between the three optical paths that slightly
decorrelate the PSFs. Two types of PSF calibrations are combined with the
differential simultaneous imaging technique to further attenuate the PSF:
reference star subtraction and instrument rotation to smooth aberrations. It is
shown that a faint companion with a DeltaH of 10 magnitudes would be detected
at 0.5 arcsec from the primary.Comment: 12 pages, 10 figures, to appear in Astronomy with High Contrast
Imaging, EAS Publications Serie
Tundra Fire Regimes in the Noatak River Watershed, Alaska: 1956-83
The location, cause, frequency, size, rotation times, and seasonal timing of tundra fires in the Noatak River watershed of northwestern Alaska were determined from Bureau of Land Management fire records for 1956-83 and satellite (LANDSAT) 1:1 000 000 scale, black and white, band 7 imagery for 1972-81. Seventy-nine fires that burned 1018 km² were detected during the 28-year period from 1956 to 1983. Most of these occurred on the valley floor below 450 m in close proximity to the Noatak River or its tributaries. However, differences in mean fire size, frequency, and rotation times varied greatly among the six physiographic regions of the watershed. All fires occurred during one of two summertime periods in June and July. The implications of this seasonal timing and comparisons of the fire regimes in the Noatak with those in other areas of northern Alaska are discussed.Key words: arctic tundra, LANDSAT imagery, Brooks Range, fire records, fire history, Alaska, Biosphere ReservesMots clés: toundra arctique, images LANDSAT, chaîne Brooks, dossiers d'incendies, histoire des incendies, Alaska, réserves de la biosphèr
Construction and measurement of the pre-series twin aperture resistive quadrupole magnet for the LHC beam cleaning insertions
CERN's Large Hadron Collider (LHC) requires 48 twin aperture resistive quadrupoles in the beam cleaning insertions. Canada is contributing these magnets to CERN in the framework of the TRIUMF-LHC collaboration contracts. A pre-series magnet was produced by Canadian industry and delivered in March 2001. This magnet incorporates important design changes that resulted from experience with a prototype magnet. The construction of this pre-series magnet and the measurements made at ALSTOM and at CERN are reported. A comparison is made between high precision pole distance measurements and the magnetic measurements performed with a rotating coil mole. Conclusions for series production and possibilities for multipole corrections are outlined. (6 refs)
Benchmarking quantum control methods on a 12-qubit system
In this letter, we present an experimental benchmark of operational control
methods in quantum information processors extended up to 12 qubits. We
implement universal control of this large Hilbert space using two complementary
approaches and discuss their accuracy and scalability. Despite decoherence, we
were able to reach a 12-coherence state (or 12-qubits pseudo-pure cat state),
and decode it into an 11 qubit plus one qutrit labeled observable pseudo-pure
state using liquid state nuclear magnetic resonance quantum information
processors.Comment: 11 pages, 4 figures, to be published in PR
Quelle rĂ©gulation pour lâarrĂȘt dâun protocole de recherche clinique de thĂ©rapie gĂ©nique somatique ? Ătat des lieux auprĂšs des cliniciens-chercheurs europĂ©ens
Depuis 2002, le dĂ©bat sur les risques associĂ©s Ă la thĂ©rapie gĂ©nique est initiĂ© suite Ă lâannonce
que deux enfants inclus dans un essai thérapeutique impliquant une thérapie génique ont
développé des effets indésirables important. En Janvier 2005, le débat sur les risques reprit suite
Ă lâinterruption du protocole sur les enfants bulle du Pr Fischer Ă lâhĂŽpital Necker de Paris. Nous
avons donc étudié le processus impliqué ainsi que la réflexion éthique associée aux décisions
dâarrĂȘt de protocole de recherche. Notre travail a Ă©tĂ© menĂ© par une Ă©quipe pluridisciplinaire
combinant chercheurs en santé, généticiens et éthiciens. Nous avons étudié la participation des
chercheurs, des patients, des institutions officielles, des comitĂ©s dâĂ©thique ainsi que des
associations de patients dans le processus de dĂ©cision dâinterruption dâun protocole de recherche.Nous avons Ă©galement analysĂ© les critĂšres jugĂ©s les plus pertinents dans lâarrĂȘt dâun protocole
de recherche. Enfin nous avons analysé le point de vue des personnes directement impliquées
dans la thĂ©rapie gĂ©nique au moyen dâun questionnaire. Toutes les personnes contactĂ©es ont
présenté un poster de recherche au congrÚs de la Société Européenne de Thérapie Génique. 62
personnes dâautant dâĂ©quipes de recherche diffĂ©rentes, de 17 pays, sur les 350 contactĂ©s ont
rĂ©pondu. Selon eux, la dĂ©cision dâarrĂȘt dâun protocole de recherche doit ĂȘtre prise suite Ă une
consultation des chercheurs, des patients, du ministĂšre de tutelle, dâune agence nationale de
rĂ©gulation ou dâun comitĂ© dâĂ©thique ; la lĂ©gitimitĂ© Ă©tant accordĂ©e Ă des dĂ©cisions prises en
commun par les chercheurs, les patients et les comitĂ©s dâĂ©thique. Les incidents sĂ©rieux et de façon
plus surprenante, les incidents moins graves sont jugés comme étant des critÚres suffisants pour
interrompre un essai. Nous avons fini par analyser les conséquences éthiques, telles que balance
bĂ©nĂ©fice/risque, processus de rĂ©gulation ou responsabilitĂ©, de ces critĂšres sur lâarrĂȘt dâun protocole
de recherche.In 2002, the debate on the risks of gene therapy was initiated following the annoucement that two
children included in a clinical trial developed serious adverse effects. In January 2005, the debate
was reignited following the interruption of the âbubble kids protocolâ at the HĂŽpital Necker in Paris.
We have thus investigated the ethical stakes involved in decisions to stop protocols. This work was
carried out by a multidisciplinary team combining ethics researchers and geneticists. We studied
the specific participation of researchers, patients, official institution, ethics committees and patient
associations in the processes that can lead to an interruption of trial.We also analysed the criterion
judged most relevant for halting a trial. Finally, we analyzed the perspective of the actors implicated
directly in the provision of gene therapy, by means of a questionnaire. All the individuals contacted
had presented a scientific poster at the European Society of Gene Therapy. 62 out of 350 persons,
from 17 countries, responded to our questionnaire. According to these respondants, decisions to stop
a trial should be taken after consultation with researchers, patients, the ministry, national agencies
or ethics committees. Legitimacy was accorded to joint decision-making by researchers, patients and
committees. Serious incidents, and surprisingly less serious incidents, clearly emerge as criterion for
stopping a trial. We conclude by analyzing the ethical consequences, such as risk/benefit ratios,
regulatory processes and responsibility, associated with these criterions and decisions to stop a trial
Canonical formulation of self-gravitating spinning-object systems
Based on the Arnowitt-Deser-Misner (ADM) canonical formulation of general
relativity, a canonical formulation of gravitationally interacting classical
spinning-object systems is given to linear order in spin. The constructed
position, linear momentum and spin variables fulfill standard Poisson bracket
relations. A spatially symmetric time gauge for the tetrad field is introduced.
The achieved formulation is of fully reduced form without unresolved
constraints, supplementary, gauge, or coordinate conditions. The canonical
field momentum is not related to the extrinsic curvature of spacelike
hypersurfaces in standard ADM form. A new reduction of the tetrad degrees of
freedom to the Einstein form of the metric field is suggested.Comment: 6 pages. v2: extended version; identical to the published one. v3:
corrected misprints in (24) and (39); improved notation; added note regarding
a further reference
UK science press officers, professional vision and the generation of expectations
Science press officers can play an integral role in helping promote expectations and hype about biomedical research. Using this as a starting point, this article draws on interviews with 10 UK-based science press officers, which explored how they view their role as science reporters and as generators of expectations. Using Goodwinâs notion of âprofessional visionâ, we argue that science press officers have a specific professional vision that shapes how they produce biomedical press releases, engage in promotion of biomedical research and make sense of hype. We discuss how these insights can contribute to the sociology of expectations, as well as inform responsible science communication.This project was funded by the Wellcome Trust (Wellcome Trust Biomedical Strategic Award 086034)
Dust-scattered X-ray halos around two Swift gamma-ray bursts: GRB 061019 and GRB 070129
Two new expanding X-ray rings were detected by the Swift XRT instrument
during early follow-up observations of GRB 061019 and GRB 070129, increasing to
5 the number of dust scattering X-ray halos observed around GRBs. Although
these two halos were particularly faint, a sensitive analysis can be performed
that optimizes the method originally developed by Tiengo & Mereghetti (2006) to
analyze dust scattering rings observed with XMM-Newton for the Swift satellite.
In the case of GRB 061019, a known giant molecular cloud is identified as the
one responsible for the scattering process, and its distance is accurately
measured (d=94040 pc) through the dynamics of the expanding ring. In the
second case, XRT observed both the main peak of the prompt emission of GRB
070129 and the scattering halo, but the small number of detected halo photons
prevents us from distinguish between different dust models.Comment: 6 pages, 8 figures; Accepted by Astronomy & Astrophysics, in pres
Investigating the Influence of High-Speed Gantry Rotation in Cardiac CT on Motion Artifacts in Aortic Stenosis Patients Not Premedicated with ÎČ-Blockers: The FAST-CCT Randomized Trial Protocol.
Coronary CT angiography (CCTA) is increasingly used as a non-invasive tool to assess coronary artery disease (CAD). However, CCTA is subject to motion artifacts, potentially limiting its clinical utility. Despite faster (0.35 and 0.28 s/rot) gantry rotation times, low (60-65 bpm) heartbeat is recommended, and the use of ÎČ-blockers is often needed. Technological advancements have resulted in the development of faster rotation speeds (0.23 s/rot). However, their added value in patients not premedicated with ÎČ-blockers remains unclear. This prospective single-center, two-arm, randomized, controlled trial aims to assess the influence of fast rotation on coronary motion artifacts, diagnostic accuracy of CCTA for CAD, and patient safety.
We will randomize a total of 142 patients aged â„ 50 scheduled for an aortic stenosis work-up to receive CCTA with either a fast (0.23) or standard (0.28 s/rot) gantry speed.
rate of CCTAs with coronary motion artifacts hindering interpretation.
assessable coronary segments rate, diagnostic accuracy against invasive coronary angiography (ICA), motion artifact magnitude per segment, contrast-to-noise ratio (CNR), and patient ionizing radiation dose. The local ethics committee has approved the protocol. Potential significance: FAST-CCT may improve motion artifact reduction and diagnosis quality, thus eliminating the need for rate control and ÎČ-blocker administration.
gov identifier: NCT05709652
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