Enriching Visual with Verbal Explanations for Relational Concepts -- Combining LIME with Aleph

With the increasing number of deep learning applications, there is a growing demand for explanations. Visual explanations provide information about which parts of an image are relevant for a classifier's decision. However, highlighting of image parts (e.g., an eye) cannot capture the relevance of a specific feature value for a class (e.g., that the eye is wide open). Furthermore, highlighting cannot convey whether the classification depends on the mere presence of parts or on a specific spatial relation between them. Consequently, we present an approach that is capable of explaining a classifier's decision in terms of logic rules obtained by the Inductive Logic Programming system Aleph. The examples and the background knowledge needed for Aleph are based on the explanation generation method LIME. We demonstrate our approach with images of a blocksworld domain. First, we show that our approach is capable of identifying a single relation as important explanatory construct. Afterwards, we present the more complex relational concept of towers. Finally, we show how the generated relational rules can be explicitly related with the input image, resulting in richer explanations

IGF2 is a potential factor in RAI-refractory differentiated thyroid cancer

Differentiated thyroid cancer (DTC) is the most frequent endocrine tumor with a good prognosis after primary treatment in most cases. By contrast, 30-40% of patients with metastatic DTC are unresponsive to I-131 radioactive iodide (RAI) treatment due to tumor dedifferentiation. Currently, underlying molecular mechanisms of dedifferentiation remain elusive and predictive biomarkers are lacking. Therefore, the present study aimed to identify molecular biomarkers in primary tumors associated with RAI refractoriness. A retrospective cohort was gathered consisting of RAI-sensitive patients with DTC and RAI-refractory patients with poorly DTC. In all patients, extensive intratumoral mutation profiling, gene fusions analysis, telomerase reverse transcriptase (TERT) promoter mutation analysis and formalin-fixed paraffin-embedded-compatible RNA sequencing were performed. Genetic analyses revealed an increased mutational load in RAI-refractory DTC, including mutations in AKT1, PTEN, TP53 and TERT promoter. Transcriptomic analyses revealed profound differential expression of insulin-like growth factor 2 (IGF2), with up to 100-fold higher expression in RAI-refractory DTC compared with in RAI-sensitive DTC cases. ELISA revealed significant lower IGF2 plasma concentrations after surgery and subsequent I-131 RAI therapy in patients with DTC compared with pretreatment baseline. Overall, the current findings suggested that the tumor-promoting growth factor IGF2 may have a potential role in acquiring RAI refractoriness.Diabetes mellitus: pathophysiological changes and therap

Late 1920s film theory and criticism as a test-case for Benjamin’s generalizations on the experiential effects of editing

This article investigates Walter Benjamin’s influential generalization that the effects of cinema are akin to the hyper-stimulating experience of modernity. More specifically, I focus on his oft-cited 1935/36 claim that all editing elicits shock-like disruption. First, I propose a more detailed articulation of the experience of modernity understood as hyper-stimulation and call for distinguishing between at least two of its subsets: the experience of speed and dynamism, on the one hand, and the experience of shock/disruption, on the other. Then I turn to classical film theory of the late 1920s to demonstrate the existence of contemporary views on editing alternative to Benjamin’s. For instance, whereas classical Soviet and Weimar theorists relate the experience of speed and dynamism to both Soviet and classical Hollywood style editing, they reserve the experience of shock/disruption for Soviet montage. In order to resolve the conceptual disagreement between these theorists, on the one hand, and Benjamin, on the other, I turn to late 1920s Weimar film criticism. I demonstrate that, contrary to Benjamin’s generalizations about the disruptive and shock-like nature of all editing, and in line with other theorists’ accounts, different editing practices were regularly distinguished by comparison to at least two distinct hyper-stimulation subsets: speed and dynamism, and shock-like disruption. In other words, contemporaries regularly distinguished between Soviet montage and classical Hollywood editing patterns on the basis of experiential effects alone. On the basis of contemporary reviews of city symphonies, I conclude with a proposal for distinguishing a third subset – confusion. This is an original manuscript / preprint of an article published by Taylor & Francis in Early Popular Visual Culture on 02 Aug 2016 available online: https://doi.org/10.1080/17460654.2016.1199322

Vorrichtung zum Fuegen von Elementen in entsprechende Aufnahmeelemente eines Objekts

Beschrieben wird eine Vorrichtung zum Fuegen von Elementen in Aufnahmeelemente eines Objekts, deren Lage und Groesse in drei Dimensionen innerhalb bestimmter Erwartungsbereiche variabel ist, mittels einer mehrachsigen Handhabungseinrichtung, deren Bewegung eine Steuereinheit steuert. Die erfindungsgemaesse Vorrichtung zeichnet sich durch die Kombination folgender Merkmale aus: - zwei elektronische Kameras sind derart angeordnet, dass ihr Abstand groesser als die Abmessung des Erwartungsbereichs in Richtung der Verbindungslinie der Kameras ist, und dass sie den gesamten Erwartungsbereich unter einem Winkel erfassen, - die Ausgangssignale der beiden Kameras sind an eine Bildauswerteeinheit angelegt, die die Ausgangssignale in ein digitales Bild zur Erfassung der Kontur der Aufnahmeelemente umwandelt, - die Steuereinheit extrahiert aus den 2*2D-Objektdaten zweidimensionalen Daten signifikanter Konturmerkmale und berechnet aus diesen Daten die dreidimensionale Position der signifikanten Ko nturmerkmale und steuert entsprechend die Handhabungseinrichtung