6 research outputs found
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
- Al-Omary Sohaib
- Al-Quossi Mohammed
- Al-Shambaty Yasir Babkir Ali
- Al-Shami Qotadah
- Al-Smirat Heba
- Al-Tahayneh Sief-Addeen
- Al-Touny Aiman
- Al-Touny Shimaa
- Al-zawaydeh Alia
- Alaa Ali
- Alabed Ebtihal
- Alagelli Fatma
- Alagoz Ahmet Can
- Alameen Hind
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- Alamlih Laith
- Alaqoubi Retaj
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- Alariby Fatima
- Alatefi Dawood
- Alathameen Nassar
- Albakosh Bashir Abobaker
- Albanopoulos Konstantinos
- Albarhomy Osama
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- Alboon Mosab
- Alboridy Muneera
- Alboueishi Asraa Ali
- Aldeges Marwan
- Aldreawi Mohammed
- Alflite Asil Omar Saleh
- Alfrijat Tamam
- Alfrjani Tariq
- Algabbasi Salima
- Algatanesh Nassib
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhaleem Ayah
- Alhaleeq Saif
- Alharam Abtisam
- Alhashimi Abdulhadi Mohammed Alhadi
- Alhassan Monzer
- Alhudhairy Sara
- Ali Ahmed
- Ali Aml
- Ali Doua
- Ali Eithar M
- Ali Iqra Fatima Munawar
- Ali Maab
- Ali Manal
- Ali Muhammad
- Ali Radwa
- Ali Rawan Alsheikh
- Ali Rzan Ali Hamedelneel
- Ali Shehroz
- Aliosin Oleg
- Aljamal Mohammad
- Aljamal Sarah
- Alkaraja Layth
- Alkaseek Akram
- Alkazali Mustafa
- Alkchr Hayat Ben Hasan Mohamed A A
- Alkhatib Abed Alazeez
- Allam Shereen
- Almahroush Marin
- Almakki Doha Mohammed Ahmed
- Alnajjar Lara
- Alnajjar Majjd
- Alnatsheh Wesam
- Alnour Ammar
- Alomar Rabiaa
- Alomari Yazan
- Alqaarh Aya
- Alragig Zahra
- Alrifae Ghaliya Mohamed H
- Alrosan Risan
- Alsagoff Sharifah Nor Amirah Syed Abdul Latiff
- Alsaid Hamza
- Alsaify Esmat
- Alsaih Sawsan
- Alsari Najah
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- Alshawadfy Abdelrhman
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- Alsheik Ahmad
- Alsori Mohamed
- Alsoudani Ali
- Altabbaa Hashem
- Altahir Mohamed
- Altair Mawadda
- Altaweel Ahmad
- Altughar Bushra
- Alvarez Matias
- Alvarez-Lozada Luis Adrian
- Alvarez-Lozada Luis Adrian
- Alwahaib Anas
- Alwash Mohammed
- Alzarga Ali
- Alzarouq Ebtisam
- Alzarroug Amal
- Alzghoul Bader
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- Amarasekara Mishka
- Amary Marwa
- Ametov Amet
- Amin Mostafa K
- Aminu Bashiru
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- Yuzgec Ayse Nilufer
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- Zaed Moahmed
- Zafar Fatima
- Zaghloul Ahmed
- Zaheer Adil
- Zaidi Faseeh
- Zain Ahmad
- Zakaria Ahmed
- Zakaria Andee Dzulkarnaen
- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study
- Author
- Aalinezhad Fatemeh
- Abdulwahed Eman
- Abidi Khalid
- Abilama Fayez
- Abousnina Fathi A.
- Abu-Sayf Natalia
- Ahmadi Fatemeh
- Ahmed Abdullah Khudhur
- Ahmed Samiul
- Akova Murat
- Al-Jadaan Mohammad
- Aldhalia Amer
- Ali Saedah
- AliAli Almajdoub Mohammed
- Aljabbary Ahmed
- Almekhlafi Ghaleb A.
- Almiqlash Bushray
- Alsisi Adel
- Amiri Fereshteh
- Amro Sarah
- Apichatbutr Yutthana
- Aqeelah Ahmed
- Arvaniti Kostoula
- Aslan Abdullah Tarik
- Atobe Kaori
- Attokaran Antony George
- Awad Ahmed K.
- Awad Maher
- Azman Abd Hamid
- Baghbanian Reza
- Bakr Lubna
- Barbier François
- Barsoum Mina
- Bassetti Matteo
- Belkhadir Z.
- Belman Daniel
- Bhadange Neeraj
- Bilkhayr Hala
- Biradar Vishwanath
- Black E.
- Borsi Seyed Hamid
- Bouaziz Mounir
- Bouhuwaish Ahmad
- Boukatta Brahim
- Bracht Hendrik
- Brewster David
- Buetti Niccolò
- Buimsaedah Ahmad
- Centeno Pablo
- Chaaban Mohammad Karam
- Chen Xiaomei
- Chiewroongroj Supattra
- Chou Nai Kuan
- Cia Cong Tat
- Conway Morris Andrew
- Dabiri Gholamreza
- De Bus Liesbet
- De Waele Jan
- Dendane Tarek
- Diab Adei
- Dwivedi Jyotsna
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbuzidi Abdurahaman
- Elhadi Muhammed
- Elhadidy Amr
- Elmandouh Omar
- Elrabi Omar
- Elsayed Ahmed
- Eroglu Ege
- Fares Aya
- Ferrer Ricard
- Finnis Mackenzie
- Fong Kean Khang
- Fourie Cheryl
- Fujitani Shigeki
- Gamra Marwa
- Geng Nan
- Ghannam A.
- Goh Ken Junyang
- Goh Qing Yuan
- Gurjar Mohan
- Hachimi Abdelhamid
- Haibo Qiu
- Hall Daniel
- Harara Belal
- Hasan Hayat Ben
- Hasan M. Shahnaz
- Hasan Rabab Shaban Ben
- Hashimoto Satoru
- Hayashi Yoshiro
- Hdada Aisha Khaled
- Hemead Hanan M.
- Homaidan Ahmed Gaber Sadik
- Hosokawa Koji
- Houfi Ashraf El
- Housni Brahim
- Hssain Ali Ait
- Hu Chungfang
- Hu Ting Yu
- Huang Min
- Ibrahim Rebecca
- Islam Mohammad Motiul
- Jackson Matthew
- Jamaluddin Muhamad Fadhil Hadi
- Jaramillo C’havala
- Javaherforoosh Fatemeh
- Jayyab Mustafa Abu
- Jeon Kyeongman
- Jianfeng Xie
- Jobran Rania
- Kagan Ilya
- Kanjaa Nabil
- Karic Edin
- Karumai Toshiyuki
- Kashipazha Davood
- Kato Hideaki
- Kiani Arash
- Ku Shih Chi
- Kuo Li Kuo
- Kuriyama Akira
- Kwa Andrea Lay Hoon
- Lance Marcus
- Laupland Kevin
- Ledtischke Anne
- Lee Sang Min
- Leone Marc
- Levin Phillip
- Li Andrew Yunkai
- Lie Sui An
- Liew Mun Thing
- Lim Jia Yan
- Lim Sung Yoon
- Lipman Jeffrey
- Litton Edward
- Luo Jili
- Mahmoodpoor Ata
- Makino Jun
- Margetts Ben
- Masjedi Mansoor
- Matsuyoshi Takeo
- Mazlan Mohd Zulfakar
- Mehraban Zahra
- Meyer Jason
- Mingmin Chen
- Mishima Yuka
- Mon Tomas
- Moorthi P. Dhakshina
- Morvillo Lic Natalia
- Mostafa Tarek
- Mouhssine Doumiri
- Nadeem Rashid
- Nafees Khalid Mahmood Khan
- Nagashima Michio
- Ng Kangqi
- Ng Louis Xiang Long
- Ng Shin Yi
- Nissar Shaikh
- Noor Zuraini Md
- Omori Koichiro
- Ong Caroline Yu Ming
- Osman Nermin
- other and
- Ouhadian Maryam
- Paiva José Artur
- Palermo Anna Maria
- Park Seung Yong
- Park Sunghoon
- Peije Li
- Pheng Lee See
- Pollock Hamish
- Povoa Pedro
- Qian Chuanyun
- Qin Bingyu
- Qiu Haibo
- Quah Jessica Lishan
- Rahman Hamizah Bt Abdul
- Ramanan Mahesh
- Rashid Nurhikmahtul Aqilah Haji Abd
- Rashidi Mahboobeh
- Regli Adrian
- Rigler Merav
- Rinka Hiroshi
- Ruckly Stéphane
- Saber Ahmed
- Sabetian Golnar
- Saito Hiroki
- Sallam Hend
- Sarode Vineet
- Sarshad Hakimeh
- Savaie Mohsen
- Saxena Manoj
- Seddiki Rachid
- Sellami Walid
- Serghini Issam
- Shigemitsu Hidenobu
- Singer Pierre
- Soar Natalie
- Soltani Farhad
- Sridharan Dhadappa Damodar
- Staiquly Quentin
- Sudhirchandra Shah
- Tabah Alexis
- Tabatabaei Seyed Mohammad Nasirodin
- Taher Ahmed Sa
- Tajvidi Ramin
- Takaki Shunsuke
- Timsit Jean François
- Tong Lee Kok
- Turki Olfa
- Tyler Steven
- Vaidyanathan R.
- Visvalingam Sheshendrasurian
- Wajdi Maazouzi Ahmed
- Walid Haji Adi Muhamad Ibnu
- Walsham James
- Wang Hao
- Wang Jinfeng
- Wang Ruilan
- Wang Yan
- Weeda Elizabeth
- Wei-Hua Lu
- Weifeng Xie
- Wong Siong Ling Danny
- Wongsurakiat Phunsup
- Wusi Qiu
- Xu Lei
- Yamasaki Masaki
- Yan Jing
- Yap Timothy
- Ye Jilu
- Ye Ling
- Yeh Yu Chang
- Yin Chengfen
- Yin Yongjie
- Yoshida Hideki
- Younes Oujidi
- Young Meredith
- Zand Farid
- Zargar Mohammad Amin
- Zeggwagh Amine Ali
- Zhang Min
- Zhao Juan
- Zhao Peng
- Zhen Wang
- Zhou Suming
- Publication venue
- Springer
- Publication date
- 01/02/2023
- Field of study
Purpose: In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated with significant mortality. Granular data are required for optimizing management, and developing guidelines and clinical trials. Methods: We carried out a prospective international cohort study of adult patients (≥ 18 years of age) with HA-BSI treated in intensive care units (ICUs) between June 2019 and February 2021. Results: 2600 patients from 333 ICUs in 52 countries were included. 78% HA-BSI were ICU-acquired. Median Sequential Organ Failure Assessment (SOFA) score was 8 [IQR 5; 11] at HA-BSI diagnosis. Most frequent sources of infection included pneumonia (26.7%) and intravascular catheters (26.4%). Most frequent pathogens were Gram-negative bacteria (59.0%), predominantly Klebsiella spp. (27.9%), Acinetobacter spp. (20.3%), Escherichia coli (15.8%), and Pseudomonas spp. (14.3%). Carbapenem resistance was present in 37.8%, 84.6%, 7.4%, and 33.2%, respectively. Difficult-to-treat resistance (DTR) was present in 23.5% and pan-drug resistance in 1.5%. Antimicrobial therapy was deemed adequate within 24 h for 51.5%. Antimicrobial resistance was associated with longer delays to adequate antimicrobial therapy. Source control was needed in 52.5% but not achieved in 18.2%. Mortality was 37.1%, and only 16.1% had been discharged alive from hospital by day-28. Conclusions: HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes.</p
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aaqil Shah
- Aaron Sanchez
- Abd Almonem Shaikh Ahmad
- Abdelrahman Shehata
- Abdelrahman Shehata
- Abdul Sillah
- Abdulkader Shaar
- AbdulRahman Sari
- Abdurrahman Abba Sheshe
- Abhishek Samuel
- Abhishek Sharma
- Abida K Sattar
- Abigail Sarmiento
- Abigail Semple
- Abrham Shitaw
- Abu Talha Siddiqui
- Adriana Scamporlino
- Agathe Seguin-Givelet
- Ahmad Sayasneh
- Ahmad Shokry
- Ahmed Elshawadfy Sherif
- Ahmed Emad Sayed Hassan
- Ahmed S Sedik
- Ahmed Samir Farahat
- Ahmed Seleim
- Ahmed Shabana
- Ahmed Shaheen
- Ahmed Shehta
- Ahmed Shirazi
- Ahmet Can Sarı
- Ahmet Necati Sanli
- Ailén Sánchez Cruz
- Aina Serra
- Aisulu Sarmenova
- Ajay Savlania
- Alaa Sharabi
- Alasdair Santini
- Alejandro Sanchez Arteaga
- Alejandro Sanchez Pellejero
- Aleksandar Sekulić
- Alexandra Schwartz
- Alexandra Sharpe
- Alexandra Shlomina
- Alexey Shilyaev
- Ali Samkari
- Ali Shafiee
- Aliaa Shamardal
- Alima Satanova
- Alistair Savage
- Alphonse Marie Sibomana
- Alvaro Eduardo Sánchez Hernández
- Alvaro Sanchez Barrueco
- Aly Sanad
- Amaia Sanz Larrainzar
- Amal Shukri
- Aman Sethi
- Amanda Shen
- Amatallah Hadi Shamsan
- Ami Shah
- Amin Siddig
- Amit Sastry
- Amjad Shah
- Amr Shalaby
- Ana Carolina Scintini Herbst
- Ana Maria Simono Charadan
- Ana Sánchez Gollarte
- Ana Sánchez Mozo
- Ana Senent-Boza
- Anand Sanmugam
- Andrea Sangheli
- Andrea Sanz Llorente
- Andrea Schmedding
- Andrea Simic
- Andreas Scheiwiller
- Andreas Schnitzbauer
- Andreea-Madalina Serban
- Andrei Shulgin
- Andrew Schache
- Andrés Sánchez-Gómez
- Aneela Shaheen
- Angelino Sanna
- Aniqa Shahzad
- Ankit Sarin
- Ann Stephany Sanchez Marmolejos
- Anna Sayers
- Anna Sánchez López
- Anneka Shah
- Anshumala Shukla Kulkarni
- Anton H Schwabegger
- Antonia Schulte
- Antonio Luciano Sarni
- Antonio Mario Scanu
- Antonio Sanchís López
- Antonio Santoro
- Anu Sandhya
- Anushka Sieunarine
- Anwar Sadat Seidu
- Anwar Shamandi
- Arjun Shajpal
- Arnaldo Neves Santos Silva
- Arshad Siddiqui
- Arunkumar Sekar
- Ashish Lal Shrestha
- Ashish Sharma
- Ashleigh Sercombe
- Astad Sidhwa
- Athanasios Saratziotis
- Athanasios Saratzis
- Athish Shetty
- Atif Sharif
- Atsushi Sawada
- Atsushi Seichi
- Aurélien Scalabre
- Ayesha Shaukat
- Aymen Shafqat
- Ayten Saracoglu
- Ayushi Shukla
- Azka Shaheen
- Babak Siavashi
- Balasupramaniam Sathesan
- Balqis Shawer
- Barbara Seeliger
- Barış Sevinç
- Bárbara Segura-Méndez
- Benedikt Schäfer
- Benedikt Schmid
- Benjamin Scott
- Berta Serrano
- Bhaskar Satsangi
- Birte Schmidt
- Blagoj Shuntov
- Blanca Santos
- Bonnie Sheu
- Brasil Silva Neto
- Brooke Short
- Bruno Sensi
- Burmaa Sanjaa
- Bushra Sayeh Mohamed Elhabashi
- Camilo Sandoval
- Can Sarica
- Carlos Ferreira Dos Santos
- Carlos San Miguel
- Carlos Sanchez Rodriguez
- Carlos Santacruz
- Carlos Shiraishi Zapata
- Carmen Emanuela Scandura
- Carmen Siebenhofer
- Catherine Sarre
- Catherine Shaw
- Catriona Shenton
- Chabwera Shumba
- Charlie Saunders
- Cherith Semple
- Christian Schauer
- Christian Schineis
- Christie Hok Yung Shum
- Christoph Schäffer
- Christoph Schmolmüller
- Christopher Scott
- Claire Sharpin
- Clarisa Simon Perez
- Claudia Sarrais Polo
- Claudia Scherl
- Codin Saon
- Concepcion Segura
- Cristian Sandu
- Cristina Sanz
- Cristina Sánchez Del Pueblo
- Cristina Sánchez Torralvo
- Dagim Shimelash
- Dainius Simcikas
- Daleen Shehadeh
- Daniel Sanabria
- Daniel Sanchez-Pelaez
- Daniel Schlager
- Daniel Schöni
- Daniel Selvaraj
- Daniel Serralta de Colsa
- Daniel Shaerf
- Darya Shlyk
- David Selwyn
- Deana Shenaq
- Denise Sievers
- Dennis Serrano
- Débora Schalge Campioto
- Diana Santana
- Diego Samudio
- Diego Sasia
- Diego Schaps
- Dima Simona
- Dimiter Shinkov
- Dimitrios Schizas
- Dimitrios Sfoungaris
- Dimple Sapre
- Divya Sarin
- Djayanti Sari
- Dmitry Shkarupa
- Dmitry Shmatov
- Donald Schweitzer
- Dorien Schneidmueller
- Dr Abhishek Sarkar
- Dr Afroz Satpathy
- Dr Ali Shami
- Dr Ashraf Shoma
- Dr Shweta Shetye
- Dr Zamir Ahmad Shah
- Dragan Serghei
- Duaa Sheikh Kadro
- Edgar Sanz
- Edoardo Segalini
- Ehab Shiban
- Ekaterina Semina
- Eleazar Santana
- Elio Fabio Sánchez Cortés
- Elisa Scarnecchia
- Elisa Sebastiani
- Elise Sarjanoja
- Elva Marita Sarte
- Ema Santos
- Emil Schemitsch
- Emily Shih
- Emma-Tina Segall
- Emmanuel Schneck
- Enrico Sartori
- Erdene Sandag
- Eric Shumba
- Erin Scott
- Erin Sergey
- Ernesto Sánchez Castillo
- Esraa Sayed
- Faaiz Ali Shah
- Fabienne Schochter
- Fabrizio Scognamillo
- Fagun Shah
- Farah Shaheen
- Farakh Shahzad
- Fareed Showqi
- Farokh Savaddar
- Farrukh Ozair Shah
- Fateh Sher
- Fatima Sanchez Cabezudo Noguera
- Fatima Serhan
- Fatima Tuz Zahra Shakir
- Fatma Sefi
- Fátima Sánchez Fernández
- Fátima Sena-Ruiz
- Federica Scolari
- Fernando Sevilla
- Filip Sianos
- Francesca Simonelli
- Francesco Selvaggi
- Franck K Sikakulya
- Françoise Schmitt
- Frederique Sauvat
- Gagandeep Sandhu
- Gary Schwartz
- Georg Scheriau
- Gerald Seitinger
- Getachew Shumye
- Ghada Shalaby
- Ghaidaa Sanjuq
- Gianluca Matteo Sampietro
- Gianmarco Saponaro
- Gilbert Samuel
- Giorgio Saraceno
- Giulia Sedda
- Giulio Santoro
- Giuseppe Sammarco
- Giuseppe Sarpietro
- Giuseppe Sica
- Giuseppe Simone
- Goran Šantak
- Gowthanan Santhirakumaran
- Götz Schmidt
- Gregory Senofsky
- Guido Sciaudone
- Guillermo Alberto Sarmiento Ramirez
- Guillermo Sanchez-Villaseñor
- Gursev Sandlas
- Habie Samuel
- Hafiz Saqib Sikandar
- Hafiz Syed Zaigham Ali Shah
- Haleema Siddique
- Hannah Sellars
- Hany Shoreem
- Harriet Shearman
- Harsha Shanthanna
- Haseeb Seriwala
- Hassan Shaukat
- Helena Silveira
- Helmut Alfredo Segovia Lohse
- Hemant Sheth
- Henry Shapiro
- Herald Rene Segovia Lohse
- Herman Sehmbi
- Hernan Sandoval
- Hijab Siddique
- Hiroyuki Seki
- Hoda Sherif
- Hrishikesh Sarkar
- Hugo Santos-Sousa
- Husam Sarayrah
- Hüsnü Şevi K
- Ian Shyaka
- Ian Simel
- Ifeoluwa Shoyombo
- Ikumi Sawada
- Imraan Sardiwalla
- Imtiaz Ahmed Shakir
- Inderpaul Samra
- Inês Isabel Sampaio da Nóvoa Gomes Miguel
- Ingmar Seiwerth
- Ioannis Sarantitis
- Ioannis Siasios
- Ipsit Shah
- Irena Sesar
- Irena Shiderova
- Irène Santos
- Irvita Sharma
- Isabel Sanchez Cuadrado
- Isabel Simal Badiola
- Isabelle Schmit
- Isaie Sibomana
- Ismael Sedano-Portillo
- Ismail Sert
- Jack Sample
- Jan Armelynn Santos
- Jan Schirnhofer
- Janahan Sarveswaran
- Jasem Seba
- Jaspreet Kaur Seehra
- Javier Sanchez Gonzalez
- Javier Serrano González
- Jean Paul Shumbusho
- Jeancarllo Silva
- Jeannie Shen
- Jenardan Sellathurai
- Jerette Schultz
- Jessica Shoemaker
- Jigar Shah
- Joana San Anton
- Joel Jesús Sánchez Estupiñan
- Johannes Sander
- John Ashutosh Santoshi
- John Sandoval
- Jonathon Sheen
- Jonida Selmani
- Jordán Scherñuk
- Jorge Dos Santos Silva
- Jorge Sancho-Muriel
- Jorge Santos
- Jorge Sanz Romera
- Jos É Santos
- Jose Maria Silva Barandiaran
- Josefin Segelman
- Josep M Segur
- Joseph Sferra
- Joseph Shalhoub
- José Antonio Sánchez Martínez
- José Ignacio Sánchez Méndez
- Joud Shiekhoni
- Joudy Shurbatji
- Juan José Segura-Sampedro
- Juan Ramón Sanz
- Julia Siebert
- Julie Sanders
- Julie Sijmons
- Justin Gabriel Schlager
- Justina Seyi-Olajide
- Justina Shikongo
- K T Matthew Seah
- Kai Sheng Saw
- Kaitlyn Sharp
- Kalai Shaw
- Kamilla Schmitz Nunes
- Kanesh Kumaran Seevalingam
- Karim Shenit
- Karishma Shah
- Karl Schwaiger
- Kathryn Schaffer
- Kemal Saracoglu
- Kenji Shigemi
- Ketan Shah
- Khaled Sarraf
- Khursheed Ahmed Samo
- Kibruyisfaw Shumbash
- Kiran Sarfraz
- Kirill Shostka
- Kohila Sigamoney
- Kozo Sato
- Kristián Šimko
- Lars Schröder
- Laura Sandland-Taylor
- Laura Sánchez Blasco
- Leonie Siemen
- Lesley Sheach
- Lilian Schwarz
- Liliana Sequeira
- Liliana Silva-Igua
- Lisa Shea
- Lokesh Sasatti
- Lorenzo Scardina
- Lorna Scullion
- Luc Hervé Samison
- Lucio Selvaggi
- Lucy Scott
- Ludmila Sidorova
- Luigi Simonelli
- Luis Sánchez-Guillén
- Madiha Saqib
- Madiha Shahid
- Mafalda Sampaio-Alves
- Mahmoud Mohamed Mohamed Shalaby
- Mahmoud Shaban
- Majd Sheikh Alganameh
- Malin Simlund
- Mamta Shah
- Manaf Sharabaji
- Manjunath Siddaiah-Subramanya
- Maphios Siamuchembu
- Marc-Olivier Sauvain
- Marcello Schiavo
- Marco Sandoval Vaez
- Marco Santos
- Margaret Shi
- Margherita Serra
- Maria Juliana Sanchez
- Maria Serra Guivernau
- Maria Shemetova
- Marián Sedlák
- Marina Sánchez Robles
- Mario Santinami
- Marisa Domingues Santos
- María José Sangüesa
- María Liz Sánchez
- María Sánchez-Rubio
- María Sol Siliato Robles
- María Victoria Simón Sanz
- Mark Seamon
- Mark Simmons
- Marta Santos Espí
- Marta Seid
- Martijn Schoneveld
- Marwah Shilfeet
- Marwan Shorman
- Maryam Sherwani
- Masaki Shiota
- Masamitsu Sanui
- Mat Salleh Sarif
- Mathilde Sarlabous
- Matteo Santoliquido
- Matteo Serenari
- Matthew Sargent
- Matthew Short
- Mauricio Sandoval Tobar
- Md Abu Sayed
- Mee Hoong See
- Melissa Silva
- Mennatallah Sheta
- Mercedes Sanz
- Mert Mahsuni Sevinc
- Michael Sander
- Michael Sander
- Michael Shaw
- Michael Shinkwin
- Miguel Sanfeliu Giner
- Miguel Sánchez Suárez
- Miguel Semião
- Milena Senica Verbic
- Mishary Shalhoub
- Miski Scerif
- Mogahid Sharfeldein
- Mohamad Sankari
- Mohamad Shareeda
- Mohamed Nafea Shaar
- Mohamed Sawalem
- Mohamed Serour
- Mohamed Shalaby
- Mohamed Shalaby
- Mohamed Sharshar
- Mohamed Shemeis
- Mohamed Sherief
- Mohamed Shetiwy
- Mohamed Shoukry
- Mohammad Nour Shashaa
- Mohammad Salman Siddiqi
- Mohammad Sanwar
- Mohammed Mouaz Shebani
- Mohammed Sbaih
- Mohammed Shahine
- Mohammed Shawqy
- Mohammed Sheriff
- Mohammed Shwin
- Momen Shawk
- Monica Serrano-Navidad
- Monira Sarih
- Moritz Schirren
- Mosa Shibani
- Mosab Shetiwy
- Moses Shodipo
- Mostafa Ahmed Shehata
- Mostafa Shalaby
- Mousa Sifat
- Muhammad Ahsan Iqbal Siddiqui
- Muhammad Assam Sarwar
- Muhammad Ather Siddiqi
- Muhammad Harris Siddique
- Muhammad Shah
- Muhammad Shakeel
- Muhammad Sharif
- Muhammad Sher E Murtaza
- Muhammad Zeeshan Sarwar
- Mujuni Samson
- Mumtaz Sarang
- Munjal Shah
- Murat Şen
- Nada Santrac
- Najat Shaban Ben Hasan
- Narendra Babu Siddaiah
- Nashat Siddiqui
- Naveen Sharma
- Nawras Shaban
- Nazanin Shahrokhi
- Nedal Semreen
- Neha Sethi
- Neil Sharma
- Nele Schmidt
- Nelson Silva
- Nevena Savković
- Nicholas Schembri
- Nicholas Segaren
- Nicolas Schlegel
- Nicoleta Aurelia Sanda
- Nidhal Siddig
- Nikolay Shefer
- Niranjan Sathianathen
- Nis Schlesinger
- Nomaan Sheikh
- Noullet Séverine
- Noura Shujaa
- Nuria Sierra
- Odongo Samuel
- Okazaki Satoshi
- Okello Simon Peter
- Olga Ioulia Semkoglou
- Oliver Lauridsen Siaw
- Oliver Schnell
- Olivia Lumiap Serevina
- Olivier Scatton
- Ondrej Simetka
- Oscar Alejandro Sánchez García
- Oscar Santes Jasso
- Oscar Serrano
- Pablo Scher
- Paolo Sapienza
- Parisah Seyed-Safi
- Patricia Serrano Méndez
- Patricia Shinondo
- Patricio Santillan-Doherty
- Patrick Schuss
- Patrick Schwartz
- Patrícia Santos
- Paulo Santos-Costa
- Pedro Saraiva
- Pedro Serralheiro
- Peter Schemmer
- Philipp Schredl
- Pierpaolo Sileri
- Pilar Santos Cidon
- Pradeep Brijkishor Sharma
- Prakash Shetty
- Prassannah Satasivam
- Predrag Savic
- Premalatha Sharavanan
- Priya Shankar
- Pushp Sankhwar
- Qusai Semrin
- Qutaiba Shah Mardan
- Raahil Shah
- Rabab Shaban Ben Hasan
- Rachel Saunders
- Rachel Savoy
- Rachel Shadbolt
- Radu Razvan Scurtu
- Raffaele Sechi
- Raghuram Sekhar
- Rahul Deo Sharma
- Rahul Saxena
- Raja Khalid Shabbir
- Rakesh Shah
- Ramazan Sarı
- Ramon Sieira-Gil
- Raquel Segura Roselló
- Rasheed Shalabi
- Raza Sayyed
- Rebecca Schembri
- Reem Sayad
- Reham Shehada
- Renato Seracchioli
- Riad Sarkis
- Riaz Hussain Siddiqui
- Ricardo São Pedro
- Riccardo Schiavina
- Richard J Shemin
- Richard Sandkamp
- Richard Schulick
- Richard Shaw
- Rina Sepúlveda
- Rita Sapage
- Rita Silva
- Roberto Santambrogio
- Rohan Shetty
- Rolf Schneider
- Roman Santana Santana
- Romil Shah
- Rosa Sanz-Gonzalez
- Rosa Sánchez
- Rose Seiberth
- Rubem Alves Silva Junior
- Rui Santos
- Rupert Scott
- Ruth Christine Schäfer
- S Ali Raza Shehrazi
- Safdar Sarwar
- Safia Siddiqui
- Said Sharawi
- Sajid Shah
- Saleh Sandoughdaran
- Salem Shaat
- Sally Shepherd
- Salma Selim
- Samantha Siahetiong
- Samar Shalaby
- Sameh Sarsik
- Sameh Shehata
- Samuel Sebastian
- Sana Shagour
- Sana Shaikh Torab
- Sandra Sanz
- Sanjeewa Seneviratne
- Sanket Sadanand Shetty
- Santhosh Kumar Sampengere Annayappa
- Santhosh Shivashankar Chikkanayakanahalli
- Santiago Sánchez-Cabús
- Sara Seegert
- Sarah Shamim
- Sarah Shiels
- Sarah Shream
- Sarbpreet Sarao
- Sari Samman
- Sato Satoshi
- Satyanarayan Sankhwar
- Saurav Sarkar
- Saydash Shamsutdinov
- Sayed Shah Nur Hussein Shah
- Scott Schimpke
- Sean Ezekiel Seow
- Sebastian Shu Yip
- Segun Segun-Busari
- Sena Sefera
- Sera Sarsam
- Seyyed Hossein Shafiei
- Shafaque Shaikh
- Shahila Sheik
- Shahrima Sheefat
- Shahzad Shamim
- Shaikh Sanjid Seraj
- Shaima Sayad
- Shashank Shekhar
- Shayan Shahidi
- Sheena Seewoonarain
- Sherief Shawki
- Shigehito Sawamura
- Shilpa Sharma
- Shivakumar Shankar
- Shomik Sengupta
- Sikachov Sergei
- Silvia Santiago Maniega
- Silvia Segattini
- Sissy-Amelie Schulz
- Sivendran Seevanayagam
- Sílvia Silva
- Smruta Shanbhag
- Sohei Satoi
- Srdjan Saso
- Srujan Sharma
- Stefan Schmidbauer
- Stefano Scabini
- Steffen Seyfried
- Stephanie Savage
- Sudip Sanyal
- Sudip Shakya
- Suliman Shah
- Susannah Shore
- Sushruta Shrivastava
- Suzette Samlalsingh
- Taariq Shaikh
- Taha Ismail Sefrioui
- Taher Sawadi
- Tainá Santos Bezerra
- Takeshi Sasaki
- Tal Shahar
- Tanisha Sharma
- Tanishq Sharma
- Tanveer Shafqat
- Tarik Sammour
- Tariq Azam Siddiqi
- Tatjana Savic Jovanovic
- Teddy Saputra
- Tedesco Silvia
- Thabet Sayed Bakir
- Theodoros Sidiropoulos
- Thiago Henrique Sigoli Pereira
- Thilo Maria Schulte
- Thomas Schroeppel
- Thomas Seisen
- Tin Sein
- Tinashe Shoko
- Tjokorda Gde Agung Senapathi
- Tobias Schaetz
- Tobias Schlesinger
- Tolulope Olayinka Sayomi
- Tomislav Sečan
- Tony Shaju
- Toshiya Shiga
- Ts Shylasree
- Tsuyoshi Sano
- Tunde T Sholadoye
- Ugam Shah
- Umberto Scovazzi
- Ushma Shah
- Usman Siddique
- Valentin Schreiter
- Vanessa Sanchez Torrents
- Vanessa Savopoulos
- Varun Sarodaya
- Vicente Simo
- Victor Santos
- Vijay Sharma
- Vijay Shetty
- Vinay Shah
- Vincenzo Scorcia
- Vinita Sangai
- Vinno Savelli
- Violeta Šetka-Čuljak
- Vlad Silaghi
- Vuk Šćepanović
- Walid Shaban
- Wan Nee Shue
- William Shelker
- Yael Sandler
- Yaron Shargall
- Yashwant Shelke
- Yassmeen Sharafeldin Mohammed
- Yi Th Ng Seow
- Yuri Sekiya
- Zahid Shafiq
- Zain Saqfalhait
- Ziyan Sheng
- Zoe Seymour
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population.The aim of this study was to inform vaccination prioritization by modelling the impact of vaccination on elective inpatient surgery. The study found that patients aged at least 70 years needing elective surgery should be prioritized alongside other high-risk groups during early vaccination programmes. Once vaccines are rolled out to younger populations, prioritizing surgical patients is advantageous
Presentation, management, and outcomes of older compared to younger adults with hospital-acquired bloodstream infections in the intensive care unit: a multicenter cohort study
- Author
- Aalinezhad Fatemeh
- Abdulwahed Eman
- Abed-Maillard S.
- Abello Anton
- Abilama Fayez
- Abousnina Fathi A.
- Abu-Sayf Natalia
- Acevedo José Oscar
- Adeola Fowotade
- Agalar Canan
- Aguilar Candy Garcia
- Ahmadi Fatemeh
- Ahmed Abdullah Khudhur
- Ahmed Samiul
- Akbas Türkay
- Akdogan Ozlem
- Akova Murat
- Aksoy Firdevs
- Aktas Sabahat Cagan
- Akyol Ahmet
- Al-Jadaan Mohammad
- Aldhalia Amer
- Alfandari Serge
- Ali Almajdoub Ali Mohammed
- Ali Fadi
- Ali Saedah
- Aljabbary Ahmed
- Almekhlafi Ghaleb A.
- Almiqlash Bushray
- Almiroudi Mariota Panagiota
- Alsisi Adel
- Altin Nilgün
- Altintas Neriman Defne
- Alves Madalena
- Amerigo Joaquin Amador
- Amiri Fereshteh
- Amro Sarah
- Anderzhanova Anastasia
- Angell Hollie
- Antcliffe David
- Antrolikar Supriya
- Aparicio Christelle
- Apichatbutr Yutthana
- Aqeelah Ahmed
- Arbelot Charlotte
- Argaud Laurent
- Arias Sonia Sousa
- Armestar Fernando
- Arnillas Maria Pilar Gracia
- Artigas Ricard Mellado
- Arvaniti Kostoula
- Asensio M. J.
- Asiyanbi Gabriel
- Aslan Abdullah Tarik
- Athanasa Zoi
- Atobe Kaori
- Attokaran Antony George
- Attwood Ben
- Auchabie Johann
- Awad Ahmed K.
- Awad Maher
- Ayestaran J. Ignacio
- Azman Abd. Hamid
- Åkerlund Joyce
- Babashev Baurzhan
- Baby Sailaja K.
- Badre Gaëtan
- Baghbanian Reza
- Baig Nadia
- Baikady R. Rao
- Bajaj Manan
- Bakr Lubna
- Banach Dorota
- Barbier François
- Baronia Arvind
- Barsoum Mina
- Batirel Ayse
- Battaglini Denise
- Baudry Thomas
- Baumer Tom
- Bayindir Yasar
- Baykam Nurcan
- Bazhykayeva Yelena
- Belkhadir Z.
- Bellina Davide
- Belman Daniel
- Belskiy Vladislav
- Bermudez Rosana Munoz
- Beuzelin M.
- Bhadange Neeraj
- Bilir Yeliz
- Bilkhayr Hala
- Biradar Vishwanath
- Bisanti Alessandra
- Biston Patrick
- Black E.
- Blasco-Navalpotro Miguel Angel
- Bloos Frank
- Bojko Jozef
- Borsi Seyed Hamid
- Bortolotti Perrine
- Bose Payel
- Botelho Isabel
- Bouaziz Mounir
- Bouhuwaish Ahmad
- Boukatta Brahim
- Bourenne Jérémy
- Bourgeois Marc
- Bracht Hendrik
- Brajkovic Ana Vujaklija
- Brewster David
- Broda Hanna
- Bruel Cédric
- Bubenek-Turconi Serban
- Buetti Niccolò
- Buimsaedah Ahmad
- Burma Yaroslava
- Cakmak Rumeysa
- Carelli Simone
- Cartoze Nuno
- Casares Vanessa
- Castanera Jérémy
- Castillo Roberto Alejandro
- Catalan Beatriz
- Centeno Pablo
- Cerman Jaroslav
- Ceyhun Solakoğlu
- Chaaban Mohammad Karam
- Chandran Jagadish
- Chantziara Vasiliki
- Chatzis Marinos
- Chen Xiaomei
- Chiewroongroj Supattra
- Chikungwa Moses
- Chou Nai-Kuan
- Chukina Maria
- Chuv Stephan Jakob
- Cia Cong-Tat
- Cobb Katherine
- Cobilinschi Cristian
- Cole Stephen
- Cortegiani Andrea
- Costa Vasco
- Coupez Elisabeth
- Covotta Marco
- Cowton Amanda
- Cunha Rui Pedro
- Custovic Aida
- Çolak Onur
- Çolak Sait
- da Costa Tito
- Dabiri Gholamreza
- Dahyot-Fizelier Claire
- Daroui Ivan
- Datta Avijatri
- Davalos-Alvarez Adrian
- De Almeida Jose
- De Bus Liesbet
- de Figueiredo António Manuel Pereira
- De Geer Lina
- De La Rica Alejandro Suarez
- De Pascale Gennaro
- De Schryver Nicolas
- De Waele Elisabeth
- De Waele Jan
- Demeret Sophie
- Demiray Emine Kubra Dindar
- Dendane Tarek
- Denys Wouter
- Desalu Ibironke
- Dessap Armand Mekonted
- Di Gravio Valentina
- Di Guardo Andrea
- Diab Adei
- Dimopoulos Georges
- Djanikian Flora
- Dolan Rachael
- Dominguez-Cherit Jose G.
- Dsilva Carol
- Duarte Tiago
- Dubler Simon
- Duburcq Thibault
- Dulac Thierry
- Duprey Matthieu
- Dwivedi Jyotsna
- Edin Alicia
- Efthymiou Anna
- El Houfi Ashraf
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbuzidi Abdurahaman
- Elhadidy Amr
- Elmandouh Omar
- Elrabi Omar
- Elsayed Ahmed
- Ercole Ari
- Erdoğan Cem
- Eremenko Aleksan
- Eroglu Ege
- Erol Çiğdem
- Ersoy Yasemin
- Ersoz Gulden
- Escudier Etienne
- Espina Lorena Forcelledo
- Evik Guliz
- Fares Aya
- Fartoukh Muriel
- Faulkner Maria
- Fernández Rubén
- Fildisis Georgios
- Filipescu Daniela Carmen
- Filipovic-Grcic Ina
- Finnis Mackenzie
- Fiorelli Silvia
- Flores Matias
- Fong Kean Khang
- Foucrier Arnaud
- Fourie Cheryl
- Francois Guy
- Franke Uwe
- Furman Mikhail
- Gaigolnik Denis
- Gainnier Marc
- Gallego Alberto Orejas
- Gamra Marwa
- Garcon Pierre
- Geng Nan
- Georgopoulou Maria
- Ghannam A.
- Ghosh Pralay
- Giacobbe Daniele Roberto
- Goh Ken Junyang
- Goh Qing Yuan
- Goksu Senay
- Gomà Gemma
- Gottschalk Antje
- Goyal Shraddha
- Graham Clive
- Gratarola Angelo
- Grigoras Ioana
- Grintescu Ioana Marina
- Gritsan Alexey
- Guesdon Charlotte
- Gundogan Kursat
- Gurja Mohan
- Guzeldag Seda
- Gürbüz Yunus
- Hachimi Abdelhamid
- Haentjens Lionel
- Haibo Qiu
- Hall Daniel
- Hamid Hytham K. S.
- Haney Michael
- Harara Belal
- Hasan Hayat Ben
- Hasan M. Shahnaz
- Hasan Rabab Shaban Ben
- Hasan Rajib
- Hashimoto Satoru
- Hayashi Yoshiro
- Hdada Aisha Khaled
- Hemead Hanan M.
- Henin Pierre
- Hermosillo Mariana
- Herrera Mara Ocotlan Gonzalez
- Hewer Tayne
- Hoffman Tomer
- Hoheisen Sandra
- Hollevoet Isabelle
- Homaidan Ahmed Gaber Sadik
- Hosokawa Koji
- Housni Brahim
- Hssain Ali Ait
- Hu Chungfang
- Hu Ting-Yu
- Huang Min
- Hugill Keith
- Humphreys Sally K.
- Huq Shihan Mahmud Redwanul
- Husain A.
- Iasonidou Cristina
- Ibrahim Rebecca
- Idowu Olusola
- Iliescu C. C.
- Imzi Nadia
- Ippolito Mariachiara
- Islam Mohammad Motiul
- Jackson Matthew
- Jain Nikhilesh
- Jamaluddin Muhamad Fadhil Hadi
- Janny Sylvie
- Jaramillo C'havala
- Javaherforoosh Fatemeh
- Jayyab Mustafa Abu
- Jeon Kyeongman
- Jhanji S.
- Jianfeng Xie
- Jobran Rania
- Johnson Aimee
- Kagan Ilya
- Kaimakamis Evangelos
- Kalem Ayşe Kaya
- Kalfon Pierre
- Kaligozhin Zhannur
- Kampolis C.
- Kanjaa Nabil
- Kannan Santhana
- Karaali Ridvan
- Karaiskos Ilias
- Karar Ali Adil Ali
- Karic Edin
- Karmakar Saurabh
- Kartal Ahmet Eroglu
- Karumai Toshiyuki
- Kashipazha Davood
- Kato Hideaki
- Kayaaslan Bircan
- Keegan Allison
- Kent Melanie
- Khade Reena
- Kiani Arash
- Kipnis Eric
- Kirdar Lutfi
- Kiwan Mazzeh
- Klouche Kada
- Kocagoz Sesin
- Kogkopoulos Evangelos
- Koksal Iftihar
- Komorowska Irmina Kaptur
- Kothari Nikhil
- Kotkowska Anna
- Kouroulas Vasilios
- Koutsoukou Vasiliki
- Kovacevic Pedja
- Krystopchuk Andriy
- Ku Shih-Chi
- Kuo Li-Kuo
- Kuriyama Akira
- Kurt Ibrahim
- Kusoglu Hulya
- Kutsogiannis Demetrios J.
- Kwa Andrea Lay Hoon
- Lance Marcus
- Larcher Romaric
- Lasic Hrvoje
- Laupland Kevin
- Layos Nathalie
- Le Guennec Loïc
- Le Meur Anthony
- Le Souhaitier Mathieu
- Leal Jesús Nicolás Pantoja
- Ledo Sara
- Ledtischke Anne
- Lee Sang-Min
- Lefrant Jean-Yves
- Lennard James
- Leone Marc
- Lepper Philippe
- Leroy Olivier
- Levin Phillip
- Li Andrew Yunkai
- Lie Sui An
- Liew Mun Thing
- Lim Jia Yan
- Lim Sung Yoon
- Ling Lowell
- Lipman Jeffrey
- Litton Edward
- Lodi Giovanni
- Loftus S.
- Lomeli-Teran Missael Vladimir Espinoza Villafuer
- Longbottom Rebecca
- Lopez Patricia Mabel
- Louis Guillaume
- Lungu Olguta
- Luo Jili
- Macfie Caroline
- Magomedov Marat
- Mahmoodpoor Ata
- Makino Jun
- Malliotakis Polychronis
- Marchalot A.
- Marcu Alexandra
- Margalit Ili
- Margetts Ben
- Marmanidou Kyriaki
- Marouli Diamantina
- Marques Ana Josefina Pinheiro
- Marsden Nicholas
- Martin-Loeches Ignacio
- Martinez Maria
- Maseda Emilio
- Masjedi Mansoor
- Massri Alexandre
- Matei Mariana Kristina
- Mateu Philippe
- Matsuyoshi Takeo
- Mazlan Mohd Zulfakar
- Mc Cree Melanie
- McCoshen Lorena
- Mcguigan Peter
- Mckee Rachel
- Mehraban Zahra
- Mehtap Selcuk
- Meleshkina Yulia
- Mendes António Carvalho
- Mer Mervyn
- Merenkov Yevgeniy
- Mesland Jean-Baptiste
- Metz Carlos
- Meyer Jason
- Mikstacki Adam
- Mingmin Chen
- Mira Jean-Paul
- Mirabella Michele
- Mishima Yuka
- Misra Krushna Chandra
- Misset Benoît
- Moldovan Leora
- Molinos Elena
- Mon Tomas
- Montefiore Pablo
- Montini Luca Maria
- Montravers P.
- Montravers Philippe
- Moorthi P. Dhakshina
- Morris Andrew Conway
- Mostafa Tarek
- Mouhssine Doumiri
- Moura José Pedro
- Mugazov Miras
- Mukherjee Sudipta
- Mulhi Randeep
- Muzaffar Syed Nabeel
- Nadeem Rashid
- Nafees Khalid Mahmood Khan
- Nagashima Michio
- Nasirodin Seyed Mohammad
- Ng Kangqi
- Ng Louis Xiang Long
- Ng Shin Yi
- Nica Alexandru
- Nikolaou Charikleia
- Nikolic Mario
- Nimbolkar Janardan
- Nissar Shaikh
- Noel Cindérella
- Noor Zuraini Md
- Novo Mariana
- Nowakowski Tomasz
- Nuccetelli Yanina
- null null
- Nunes Cristina
- Ñamendys-Silva Silvio A.
- Oikonomou Marina
- Oladimeji Motunrayo
- Olatosi John
- Omori Koichiro
- Ong Caroline Yu Ming
- Opdenacker Godelive
- Opolu Szpital Wojewodzki W.
- Osman Nermin
- Ouhadian Maryam
- Ozair Ahmad
- Ozgen Cansu
- Ozturk Barcin
- Pagani Jl
- Pahuja Madhumati
- Palermo Anna Maria
- Papageorgiou Eirini
- Papanikolaou M.
- Papathanakos Georgios
- Papoti Sofia
- Parcell Benjamin J.
- Park Seung Yong
- Park Sunghoon
- Pascoalinho Dulce
- Pasieka Bastian
- Paskalis Harry
- Patel Jamie
- Patel Mayur
- Patrier Mme Juliette
- Paulet Rémi
- Peichota Mariusz
- Peije Li
- Pelagalli Lorella
- Pelosi Paolo
- Pereira Énio
- Pereira Tiago
- Perez-Nieto Orlando R.
- Perm E. A. Vagner
- Perrigault Pierre-François
- Persec Jasminka
- Petros Sirak
- Pheng Lee See
- Philippart François
- Pietraszek-Grzywaczewska Iwona
- Pinto Ana Rios
- Pollock Hamish
- Popescu Mihai
- Porcile Elisa
- Póvoa Pedro
- Prazak Josef
- Predoi Cornelia Elena
- Prendki Virginie
- Prieto Emilio Garcia
- Psallida Vasiliki
- Qian Chuanyun
- Qin Bingyu
- Quah Jessica Lishan
- Queiró Joana
- Quesada María Dolores
- R Vaidyanathan
- Rabbani Raihan
- Radonic Radovan
- Raguer Laura
- Rahman Hamizah Bt Abdul
- Raj Ashok
- Ramanan Mahesh
- Rashid Nurhikmahtul Aqilah Haji Abd
- Rashidi Mahboobeh
- Rathod Darshana
- Razazi Keyvan
- Regli Adrian
- Renaud Paul Jean
- Renuka M. K.
- Retselas Ioannis
- Reyes Luis Felipe
- Rigler Merav
- Rinka Hiroshi
- Ritzema Jenny
- Rizzo Anna Chiara
- Rocca Ricard Ferrer
- Rocco Monica
- Rodriguez M.
- Roger Claire
- Roig Regina
- Rojo Roceld
- Romanou Vasiliki
- Romero-Gonzalez Juan P.
- Roshdy Ashraf
- Rosman Jérémy
- Routledge Matthew
- Rubina Noor Ahmedi
- Ruckly Stephane
- Ruckly Stéphane
- Ruppe Etienne
- Saber Ahmed
- Sabetian Golnar
- Saidahmed Elfayadh
- Saito Hiroki
- Sakagianni Aikaterini
- Sakan Sanja
- Sakkalis Anastasios
- Sales Gabriele
- Salgado Maria
- Sallam Hend
- Saltoglu Nese
- Samdani Pratit
- Sanderson Amanda
- Santos Emilio Diaz
- Saracoglu Kemal Tolga
- Sari Ali
- Sarode Vineet
- Sarshad Hakimeh
- Sarton Benjamine
- Savaie Mohsen
- Saxena Manoj
- Sánchez-Hurtado Luis
- Schlevenin Maria Grazia
- Schmidt Karsten
- Seddiki Rachid
- Segura Matías
- Sellami Walid
- Serck Nicolas
- Serghini Issam
- Sharma Ankur
- Sharma Priya
- Sheshala Kaladhar
- Shigemitsu Hidenobu
- Siami Shidasp
- Siddiqui Suhail Sarwar
- Silva Stein
- Singer Pierre
- Singh Ritu
- Sjövall Fredrik
- Sligl Wendy
- Smith Tim
- Smonig Roland
- Smyrniotis Dimitrios
- Soar Natalie
- Sokhan Anton
- Soltan Marina
- Soltani Farhad
- Souweine Bertrand
- Spahic Dzana
- Sridharan Dhadappa Damodar
- Sudhirchandra Shah
- Sungurtekin Hulya
- Svensson Carl Johan
- Szakmany Tamas
- Szczesniak Anna
- Tabah Alexis
- Taher Ahmed Sa
- Tajvidi Ramin
- Takaki Shunsuke
- Talan Leyla
- Tamowicz Barbara
- Tatham Kate
- Tejeda-Huezo Brigitte
- Telli Murat
- Temirov Talgat
- Templeton Maie
- Teresa Ana
- Theodorou Vasiliki
- Thomas-Rueddel Daniel
- Thompson Patricia
- Thyrault Martial
- Tilley Rebecca E.
- Timsit Jean-François
- Timuroglu Arif
- Tinaslanidis George
- Tizard Kate
- Tomas Ernesto Deloya
- Tomescu Dana
- Tong Lee Kok
- Torlinski Tomasz
- Torre Valentina Della
- Tran Marc
- Tribulev Maksim
- Tunay Burcu
- Turki Olfa
- Tyler Steven
- Ubeda Alejandro
- Udy Andrew
- Ugwu Euphemia Mgbosoro
- Umbetzhanov Yerlan
- Valeanu Liana
- Vargas Joel
- Vasileiou Maria
- Vera Paula
- Viderman Dmitriy
- Vistovskaya Natala
- Visvalingam Sheshendrasurian
- Voiriot Guillaume
- Wajdi Maazouzi Ahmed
- Walczak-Wieteska Paulina
- Walid Haji Adi Muhamad Ibnu
- Walsham James
- Wang Hao
- Wang Jinfeng
- Wang Ruilan
- Wang Yan
- Wasowska Dominika
- Weeda Elizabeth
- Wei-Hua Lu
- Weifeng Xie
- Weiss Emmanuel
- Wempe Carola
- Wittebole Xavier
- Wong Siong Ling Danny
- Wongsurakiat Phunsup
- Wusi Qiu
- Xu Lei
- Yahav Dafna
- Yakubu Saidu Yusuf
- Yamasaki Masaki
- Yan Jing
- Yap Timothy
- Ye Jilu
- Ye Ling
- Yeh Yu Chang
- Yilmaz Mesut
- Yin Chengfen
- Yin Yongjie
- Yonan Aimee
- Yoshida Hideki
- Younes Oujidi
- Young Meredith
- Zaki Ahmed
- Zand Farid
- Zappela N.
- Zargar Mohammad Amin
- Zeggwagh Amine Ali
- Zhang Min
- Zhao Juan
- Zhao Peng
- Zhen Wang
- Zhou Suming
- Zlojutro Biljana
- Zormpa Artemis
- Zubareva Nadezhda
- Zuccaro Francesco
- Publication venue
- Publication date
- 13/06/2024
- Field of study
Purpose: Older adults admitted to the intensive care unit (ICU) usually have fair baseline functional capacity, yet their age and frailty may compromise their management. We compared the characteristics and management of older (≥ 75 years) versus younger adults hospitalized in ICU with hospital-acquired bloodstream infection (HA-BSI). Methods: Nested cohort study within the EUROBACT-2 database, a multinational prospective cohort study including adults (≥ 18 years) hospitalized in the ICU during 2019-2021. We compared older versus younger adults in terms of infection characteristics (clinical signs and symptoms, source, and microbiological data), management (imaging, source control, antimicrobial therapy), and outcomes (28-day mortality and hospital discharge). Results: Among 2111 individuals hospitalized in 219 ICUs with HA-BSI, 563 (27%) were ≥ 75 years old. Compared to younger patients, these individuals had higher comorbidity score and lower functional capacity; presented more often with a pulmonary, urinary, or unknown HA-BSI source; and had lower heart rate, blood pressure and temperature at presentation. Pathogens and resistance rates were similar in both groups. Differences in management included mainly lower rates of effective source control achievement among aged individuals. Older adults also had significantly higher day-28 mortality (50% versus 34%, p < 0.001), and lower rates of discharge from hospital (12% versus 20%, p < 0.001) by this time. Conclusions: Older adults with HA-BSI hospitalized in ICU have different baseline characteristics and source of infection compared to younger patients. Management of older adults differs mainly by lower probability to achieve source control. This should be targeted to improve outcomes among older ICU patients
The role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections
- Author
- Aalinezhad Fatemeh
- Abdulwahed Eman
- Abed-Maillard S.
- Abello Anton
- Abidi Khalid
- Abillama Fayez
- Abousnina Fathi A.
- Abu-Sayf Natalia
- Acevedo José Oscar
- Adekola Oyebola O.
- Adeola Fowotade
- Agalar Canan
- Aguilar Candy Garcia
- Ahmadi Fatemeh
- Ahmed Abdullah Khudhur
- Ahmed Samiul
- Akdogan Ozlem
- Akova Murat
- Akova Murat
- Aksoy Firdevs
- Aktas Sabahat Cagan
- Akyol Ahmet
- Al-Jadaan Mohammad
- Aldhalia Amer
- Alfandari Serge
- Ali Fadi
- Ali Saedah
- AliAli Almajdoub Mohammed
- Aljabbary Ahmed
- Almekhlafi Ghaleb A.
- Almiqlash Bushray
- Almiroudi Mariota Panagiota
- Alsisi Adel
- Altin Nilgün
- Altintas Neriman Defne
- Alves Madalena
- Amerigo Joaquin Amador
- Amiri Fereshteh
- Amro Sarah
- Anderzhanova Anastasia
- Angell Hollie
- Antcliffe David
- Antrolikar Supriya
- Aparicio Christelle
- Apichatbutr Yutthana
- Aqeelah Ahmed
- Arbelot Charlotte
- Argaud Laurent
- Arias Mario
- Arias Sonia Sousa
- Armestar Fernando
- Arnillas Maria Pilar Gracia
- Artigas Ricard Mellado
- Arvaniti Kostoula
- Arvaniti Kostoula
- Asiyanbi Gabriel
- Aslan Abdullah Tarik
- Aslan Abdullah Tarık
- Athanasa Zoi
- Atobe Kaori
- Attokaran Antony George
- Attwood Ben
- Auchabie Johann
- Awad Ahmed K.
- Awad Maher
- Ayestaran J. Ignacio
- Azman Abd. Hamid
- Åkerlund Joyce
- Babashev Baurzhan
- Baby Sailaja K.
- Badre Gaëtan
- Baghbanian Reza
- Baig Nadia
- Baikady R. Rao
- Bajaj Manan
- Bakr Lubna
- Banach Dorota
- Barbier François
- Barbier François
- Baronia Arvind
- Barsoum Mina
- Bassetti Matteo
- Bassetti Matteo
- Batirel Ayse
- Battaglini Denise
- Baudry Thomas
- Baumer Tom
- Bayindir Yasar
- Baykam Nurcan
- Bazhykayeva Yelena
- Belkhadir Z.
- Bellina Davide
- Belman Daniel
- Belskiy Vladislav
- Bermudez Rosana Munoz
- Beuzelin M.
- Bhadange Neeraj
- Bilir Yeliz
- Bilkhayr Hala
- Biradar Vishwanath
- Bisanti Alessandra
- Biston Patrick
- Black E.
- Blasco-Navalpotro Miguel Angel
- Bloos Frank
- Bojko Jozef
- Borsi Seyed Hamid
- Bortolotti Perrine
- Bose Payel
- Botelho Isabel
- Bouaziz Mounir
- Bouhuwaish Ahmad
- Boukatta Brahim
- Bourenne Jérémy
- Bourgeois Marc
- Bracht Hendrik
- Brajkovic Ana Vujaklija
- Brewster David
- Broda Hanna
- Bruel Cédric
- Bubenek-Turconi Serban
- Buetti Niccolò
- Buetti Niccolò
- Buimsaedah Ahmad
- Burma Yaroslava
- C. Kampolis null
- Cakmak Rumeysa
- Carelli Simone
- Cartoze Nuno
- Casares Vanessa
- Castanera Jérémy
- Castillo Roberto Alejandro
- Catalan Beatriz
- Centeno Pablo
- Cerman Jaroslav
- Ceyhun Solakoğlu
- Chaaban Mohammad Karam
- Chandran Jagadish
- Chantziara Vasiliki
- Chatzis Marinos
- Chen Xiaomei
- Chiewroongroj Supattra
- Chikungwa Moses
- Chou Nai-Kuan
- Chukina Maria
- Cia Cong-Tat
- Cobb Katherine
- Cobilinschi Cristian
- Cole Stephen
- Conway Morris Andrew
- Cortegiani Andrea
- Cortegiani Andrea
- Costa Vasco
- Cotoia Antonella
- Coupez Elisabeth
- Covotta Marco
- Cowton Amanda
- Cunha Rui Pedro
- Custovic Aida
- Çolak Onur
- Çolak Sait
- da Costa Tito
- Dabiri Gholamreza
- Dahyot-Fizelier Claire
- Daroui Ivan
- Datta Avijatri
- Davalos-Alvarez Adrian
- De Bus Liesbet
- De Bus Liesbet
- de Figueiredo António Manuel Pereira
- De Geer Lina
- De La Rica Alejandro Suarez
- De Pascale Gennaro
- De Schryver Nicolas
- De Waele Elisabeth
- De Waele Jan
- De Waele Jan J.
- Demeret Sophie
- Demiray Emine Kubra Dindar
- Dendane Pr Tarek
- Denys Wouter
- Desalu Ibironke
- Dessap Pr Armand Mekonted
- Di Gravio Valentina
- Di Guardo Andrea
- Diab Adei
- Dimopoulos Pr Georges
- Djanikian Flora
- Dolan Rachael
- Dominguez-Cherit Jose G.
- Dsilva Carol
- Duarte Tiago
- Dubler Simon
- Duburcq Thibault
- Dulac Thierry
- Duprey Matthieu
- Dwivedi Jyotsna
- D’herbon Vall
- Edin Alicia
- Efthymiou Anna
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbuzidi Abdurahaman
- Elhadi Muhammed
- Elhadidy Amr
- Elmandouh Omar
- Elrabi Omar
- Elsayed Ahmed
- Ercole Ari
- Erdoğan Cem
- Eremenko Aleksandr
- Eroglu Ahmet
- Eroglu Ege
- Erol Çiğdem
- Ersoy Yasemin
- Ersoz Gulden
- Escudier Etienne
- Espina Lorena Forcelledo
- Evik Guliz
- Fares Aya
- Fartoukh Muriel
- Faulkner Maria
- Fernández Rubén
- Ferrer Ricard
- Fildisis Georgios
- Filipescu Daniela Carmen
- Filipovic-Grcic Ina
- Finnis Mackenzie
- Fiorelli Silvia
- Flores Matias
- Fong Kean Khang
- Foucrier Arnaud
- Fourie Cheryl
- Francois Guy
- Franke Uwe
- Fujitani Shigeki
- Furman Mikhail
- Gaigolnik Denis
- Gainnier Marc
- Gallego Alberto Orejas
- Gamra Marwa
- Garcon Pierre
- Geng Nan
- Georgopoulou Maria
- Ghannam A.
- Ghosh Pralay
- Giacobbe Daniele
- Giacobbe Daniele Roberto
- Goh Ken Junyang
- Goh Qing Yuan
- Goksu Senay
- Gomà Gemma
- Gottschalk Antje
- Goyal Shraddha
- Graham Clive
- Gratarola Angelo
- Grigoras Ioana
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Alexey
- Guesdon Charlotte
- Guimarães Nádia
- Gundogan Kursat
- Gurjar Mohan
- Gurjar Mohan
- Guzeldag Seda
- Gürbüz Yunus
- Hachimi Abdelhamid
- Haentjens Lionel
- Haibo Qiu
- Hall Daniel
- Hamid Hytham K. S.
- Haney Michael
- Harara Belal
- Hasan Hayat Ben
- Hasan M. Shahnaz
- Hasan Rabab Shaban Ben
- Hasan Rajib
- Hashimoto Satoru
- Hayashi Yoshiro
- Hdada Aisha Khaled
- Hemead Hanan M.
- Henin Pierre
- Hermosillo Mariana
- Hernandez Aaron Mark
- Herrera Mara Ocotlan Gonzalez
- Hewer Tayne
- Hoheisen Sandra
- Hollevoet Isabelle
- Homaidan Ahmed Gaber Sadik
- Hosokawa Koji
- Houfi Ashraf El
- Housni Brahim
- Hssain Ali Ait
- Hu Chungfang
- Hu Ting-Yu
- Huang Min
- Hugill Keith
- Humphreys Miss Sally K.
- Huq Shihan Mahmud Redwanul
- Husain A.
- Iasonidou Cristina
- Ibrahim Rebecca
- Idowu Olusola
- Iliescu C. C.
- Imzi Nadia
- Ippolito Mariachiara
- Islam Mohammad Motiul
- Jackson Matthew
- Jain Nikhilesh
- Jakob Stephan
- Jamaluddin Muhamad Fadhil Hadi
- Janny Sylvie
- Jaramillo C’havala
- Javaherforoosh Fatemeh
- Jayyab Mustafa Abu
- Jeon Kyeongman
- Jhanji S.
- Jobran Rania
- Johnson Aimee
- Kagan Ilya
- Kaimakamis Evangelos
- Kalem Ayşe Kaya
- Kalfon Pierre
- Kaligozhin Zhannur
- Kanjaa Nabil
- Kannan Santhana
- Karaali Ridvan
- Karaiskos Ilias
- Karar Ali Adil Ali
- Karic Edin
- Karmakar Saurabh
- Karumai Toshiyuki
- Kashipazha Davood
- Kato Hideaki
- Kayaaslan Bircan
- Kayaaslan Bircan
- Keegan Allison
- Kent Melanie
- Khade Reena
- Kiani Arash
- Kipnis Eric
- Klouche Kada
- Kocagoz Sesin
- Kogkopoulos Evangelos
- Koksal Iftihar
- Komorowska Irmina Kaptur
- Kothari Nikhil
- Kotkowska Anna
- Kouroulas Pr Vasilios
- Koutsoukou Vasiliki
- Kovacevic Pedja
- Krystopchuk Andriy
- Ku Shih-Chi
- Kuo Li-Kuo
- Kuriyama Akira
- Kurt Ibrahim
- Kusoglu Hulya
- Kutsogiannis Demetrios J.
- Kwa Andrea Lay Hoon
- Lance Marcus
- Larcher Romaric
- Lasic Hrvoje
- Laupland Kevin
- Layos Nathalie
- Le Guennec Loïc
- Le Meur Anthony
- Le Souhaitier Mathieu
- Leal Jesús Nicolás Pantoja
- Ledo Sara
- Ledtischke Anne
- Lee Sang-Min
- Lefrant Jean-Yves
- Lennard James
- Leone Marc
- Leone Pr Marc
- Lepper Philippe
- Leroy Olivier
- Levin Phillip
- Li Andrew Yunkai
- Lie Sui An
- Liew Mun Thing
- Lim Jia Yan
- Lim Sung Yoon
- Ling Lowell
- Lipman Jeffrey
- Litton Edward
- Lodi Giovanni
- Loftus S.
- Lomeli-Teran Manuel
- Longbottom Rebecca
- Lopez Patricia Mabel
- Louis Guillaume
- Lungu Olguta
- Luo Jili
- Macfie Caroline
- Magomedov Marat
- Mahmoodpoor Ata
- Makino Jun
- Malliotakis Polychronis
- Marchalot A.
- Marcu Alexandra
- Margetts Ben
- Marmanidou Kyriaki
- Marouli Diamantina
- Marques Ana Josefina Pinheiro
- Marsden Nicholas
- Martin-Loeches Ignacio
- Martinez Maria
- Maseda Emilio
- Masjedi Mansoor
- Massri Alexandre
- Matei Mariana Kristina
- Mateu Philippe
- Matsuyoshi Takeo
- Mazlan Mohd Zulfakar
- Mc Cree Melanie
- McCoshen Lorena
- Mcguigan Peter
- Mckee Rachel
- Mehraban Zahra
- Mehtap Selcuk
- Meleshkina Yulia
- Mendes António Carvalho
- Mer Mervyn
- Merenkov Yevgeniy
- Mesland Jean-Baptiste
- Metz Carlos
- Meyer Jason
- Mikstacki Adam
- Mingmin Chen
- Mira Jean-Paul
- Mirabella Michele
- Mishima Yuka
- Misra Krushna Chandra
- Misset Benoît
- Moldovan Leora
- Molinos Elena
- Mon Tomas
- Montefiore Pablo
- Montini Luca Maria
- Montravers Philippe
- Montravers Pr P.
- Montrucchio Giorgia
- Montrucchio Giorgia
- Moorthi Dhakshina
- Morris Andrew Conway
- Morris Andrew Conway
- Morvillo Lic Natalia
- Mostafa Tarek
- Mouhssine Doumiri
- Moura José Pedro
- Mugazov Miras
- Mukherjee Sudipta
- Mulhi Randeep
- Muzaffar Syed Nabeel
- N. Zappela null
- Nadeem Rashid
- Nafees Khalid Mahmood Khan
- Nagashima Michio
- Ng Kangqi
- Ng Louis Xiang Long
- Ng Shin Yi
- Nica Alexandru
- Nikolaou Charikleia
- Nikolic Mario
- Nissar Shaikh
- Noel Cindérella
- Noor Zuraini Md
- Novo Mariana
- Nowakowski Tomasz
- Nuccetelli Yanina
- null null
- Nunes Cristina
- Ñamendys-Silva Silvio A.
- Oikonomou Marina
- Oladimeji Motunrayo
- Olatosi John
- Omori Koichiro
- Ong Caroline Yu Ming
- Opdenacker Godelive
- Osman Nermin
- Ouhadian Maryam
- Ozair Ahmad
- Ozgen Cansu
- Ozturk Barcin
- Pagani Jl
- Pahuja Madhumati
- Paiva José Artur
- Paiva José-Artur
- Palermo Anna Maria
- Papageorgiou Eirini
- Papanikolaou M.
- Papathanakos A. /Pr Georgios
- Papoti Sofia
- Parcell Benjamin J.
- Park Seung Yong
- Park Sunghoon
- Pascoalinho Dulce
- Pasieka Bastian
- Paskalis Harry
- Patel Jamie
- Patel Mayur
- Patrier Juliette
- Paulet Rémi
- Peichota Mariusz
- Peije Li
- Pelagalli Lorella
- Pelosi Paolo
- Pereira Énio
- Pereira Tiago
- Perez-Nieto Orlando R.
- Perrigault Pierre-François
- Persec Jasminka
- Petros Sirak
- Pheng Lee See
- Philippart François
- Pietraszek-Grzywaczewska Iwona
- Pinto Ana Rios
- Pollock Hamish
- Popescu Mihai
- Porcile Elisa
- Póvoa Pedro
- Prazak Josef
- Predoi Cornelia Elena
- Prieto Emilio Garcia
- Psallida Vasiliki
- Qian Chuanyun
- Qin Bingyu
- Qiu Haibo
- Quah Jessica Lishan
- Queiró Joana
- Quesada María Dolores
- Rabbani Raihan
- Rabbani Raihan
- Radonic Radovan
- Raguer Laura
- Rahman Hamizah Bt Abdul
- Raj Ashok
- Ramanan Mahesh
- Rashid Nurhikmahtul Aqilah Haji Abd
- Rashidi Mahboobeh
- Rathod Darshana
- Razazi Keyvan
- Regli Adrian
- Renaud Paul Jean
- Renta Foteini
- Renuka M. K.
- Retselas Ioannis
- Reyes Luis Felipe
- Rigler Merav
- Rinka Hiroshi
- Ritzema Jenny
- Rizzo Anna Chiara
- Rocca Ricard Ferrer
- Rocca Ricard Ferrer
- Rocco Monica
- Roger Claire
- Roig Regina
- Rojo Roceld
- Romanou Vasiliki
- Romero-Gonzalez Juan P.
- Roshdy Ashraf
- Rosman Jérémy
- Routledge Matthew
- Rubina Noor Ahmedi
- Ruckly Stephane
- Ruckly Stéphane
- Ruppe Etienne
- Saber Ahmed
- Sabetian Golnar
- Saidahmed Elfayadh
- Saito Hiroki
- Sakagianni Aikaterini
- Sakan Sanja
- Sakkalis Anastasios
- Sales Gabriele
- Salgado Dra Maria
- Sallam Hend
- Saltoglu Nese
- Samdani Pratit
- Sanderson Amanda
- Sanousi Bashir El
- Santos Emilio Diaz
- Saracoglu Kemal Tolga
- Sari Ali
- Sarode Vineet
- Sarshad Hakimeh
- Sarton Benjamine
- Savaie Mohsen
- Saxena Manoj
- Sánchez-Hurtado Luis
- Schlevenin Maria Grazia
- Schmidt Karsten
- Seddiki Pr Rachid
- Segura Matías
- Sellami Pr Walid
- Serck Nicolas
- Serghini Issam
- Setti Nour
- Sharma Ankur
- Sharma Priya
- Shekhar Saurav
- Sheshala Kaladhar
- Shigemitsu Hidenobu
- Siami Shidasp
- Siddiqui Suhail Sarwar
- Silva Stein
- Singer Pierre
- Singh Ritu
- Sjovall Fredrik
- Sligl Wendy
- Sligl Wendy
- Sligl Wendy
- Smith Tim
- Smonig Roland
- Smyrniotis Dimitrios
- Soar Natalie
- Sokhan Anton
- Soltan Marina
- Soltani Farhad
- Soulountsi Vasiliki
- Souweine Bertrand
- Spahic Dzana
- Sridharan Dhadappa Damodar
- Sudhirchandra Shah
- Sulaiman Helmi
- Sungurtekin Hulya
- Svensson Carl Johan
- Szakmany Tamas
- Szczesniak Anna
- Tabah Alexis
- Tabah Alexis
- Tabatabaei Seyed Mohammad Nasirodin
- Taher Ahmed Sa
- Tajvidi Ramin
- Takaki Shunsuke
- Talan Leyla
- Tamowicz Barbara
- Tatham Kate
- Tejeda-Huezo Brigitte
- Telli Murat
- Temirov Talgat
- Templeton Maie
- Teresa Ana
- Theodorou Vasiliki
- Thomas-Rueddel Daniel
- Thompson Patricia
- Thyrault Martial
- Tilley Rebecca E.
- Timsit Jean-François
- Timsit Jean-François
- Timuroglu Arif
- Tinaslanidis George
- Tizard Kate
- Tomas Ernesto Deloya
- Tomescu Dana
- Tong Lee Kok
- Torlinski Tomasz
- Torre Valentina Della
- Tran Marc
- Tribulev Maksim
- Tunay Burcu
- Turki Olfa
- Tyler Steven
- Ubeda Alejandro
- Udy Andrew
- Ugwu Euphemia Mgbosoro
- Vaidyanathan R.
- Valeanu C. C. IliescuLiana
- Valeanu Liana
- Vanderhaeghen Sofie F. M.
- Vargas Joel
- Vasileiou Maria
- Vera Paula
- Vidal Gabriela
- Viderman Dmitriy
- Villafuerte Missael Vladimir Espinoza
- Vistovskaya Natala
- Visvalingam Sheshendrasurian
- Voiriot Guillaume
- Wajdi Maazouzi Ahmed
- Walczak-Wieteska Paulina
- Walid Haji Adi Muhamad Ibnu
- Walsham James
- Wang Hao
- Wang Jinfeng
- Wang Ruilan
- Wang Yan
- Wasowska Dominika
- Weeda. Elizabeth
- Wei-Hua Lu
- Weifeng Xie
- Weiss Emmanuel
- Wempe Carola
- Wittebole Xavier
- Wong Siong Ling Danny
- Wongsurakiat Phunsup
- Wusi Qiu
- Xie Jianfeng
- Xu Lei
- Yakubu Saidu Yusuf
- Yamasaki Masaki
- Yan Jing
- Yap Timothy
- Ye Jilu
- Ye Ling
- Yeh Tony Yu-Chang
- Yilmaz Mesut
- Yin Chengfen
- Yin Yongjie
- Ymbetzhanov Yerlan
- Yonan Aimee
- Yoshida Hideki
- Younes Oujidi
- Young Meredith
- Zaki Ahmed
- Zand Farid
- Zargar Mohammad Amin
- Zeggwagh Pr Amine Ali
- Zhang Min
- Zhao Juan
- Zhao Peng
- Zhen Wang
- Zhou Suming
- Zlojutro Biljana
- Zormpa Artemis
- Zubareva Nadezhda
- Zuccaro Francesco
- Publication venue
- Publication date
- 18/03/2024
- Field of study
Purpose: The primary objective of this study was to evaluate the associations between centre/country-based factors and two important process and outcome indicators in patients with hospital-acquired bloodstream infections (HABSI). Methods: We used data on HABSI from the prospective EUROBACT-2 study to evaluate the associations between centre/country factors on a process or an outcome indicator: adequacy of antimicrobial therapy within the first 24 h or 28-day mortality, respectively. Mixed logistical models with clustering by centre identified factors associated with both indicators. Results: Two thousand two hundred nine patients from two hundred one intensive care units (ICUs) were included in forty-seven countries. Overall, 51% (n = 1128) of patients received an adequate antimicrobial therapy and the 28-day mortality was 38% (n = 839). The availability of therapeutic drug monitoring (TDM) for aminoglycosides everyday [odds ratio (OR) 1.48, 95% confidence interval (CI) 1.03-2.14] or within a few hours (OR 1.79, 95% CI 1.34-2.38), surveillance cultures for multidrug-resistant organism carriage performed weekly (OR 1.45, 95% CI 1.09-1.93), and increasing Human Development Index (HDI) values were associated with adequate antimicrobial therapy. The presence of intermediate care beds (OR 0.63, 95% CI 0.47-0.84), TDM for aminoglycoside available everyday (OR 0.66, 95% CI 0.44-1.00) or within a few hours (OR 0.51, 95% CI 0.37-0.70), 24/7 consultation of clinical pharmacists (OR 0.67, 95% CI 0.47-0.95), percentage of vancomycin-resistant enterococci (VRE) between 10% and 25% in the ICU (OR 1.67, 95% CI 1.00-2.80), and decreasing HDI values were associated with 28-day mortality. Conclusion: Centre/country factors should be targeted for future interventions to improve management strategies and outcome of HABSI in ICU patients
Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study
- Author
- Aalinezhad Fatemeh
- Abdulwahed Eman
- Abed-Maillard S.
- Abidi Khalid
- Abilama Fayez
- Abousnina Fathi A.
- Abu-Sayf Natalia
- Acevedo José Oscar
- Adeola Fowotade
- Agalar Canan
- Aguilar Candy Garcia
- Ahmadi Fatemeh
- Ahmed Abdullah Khudhur
- Ahmed Samiul
- Akbas Türkay
- Akdogan Ozlem O.
- Akova Murat
- Akova Murat
- Aksoy Firdevs
- Aktas Sabahat Cagan
- Akyol Ahmet
- Al-Jadaan Mohammad
- Aldhalia Amer
- Alfandari Serge
- Ali Fadi
- Ali Saedah
- AliAli Almajdoub Mohammed
- Aljabbary Ahmed
- Almekhlafi Ghaleb A.
- Almiqlash Bushray
- Almiroudi Mariota Panagiota
- Alonzo Microbiologa Irene
- Alsisi Adel
- Alsisi Adel
- Altin Nilgün
- Altintas Neriman Defne
- Alves Madalena
- Amerigo Joaquin Amador
- Amiri Fereshteh
- Amro Sarah
- Anderzhanova Anastasia
- Angell Hollie
- Antcliffe David
- Antrolikar Supriya
- Aparicio Christelle
- Aparicio Dra Marta
- Apichatbutr Yutthana
- Aqeelah Ahmed
- Arbelot Charlotte
- Argaud Laurent
- Arias Sonia Sousa
- Armestar Fernando
- Arnillas Maria Pilar Gracia
- Arvaniti Kostoula
- Arvaniti Kostoula
- Asensio Dra Mj
- Asiyanbi Gabriel
- Aslan Abdullah Tarik
- Aslan Abdullah Tarik
- Athanasa Zoi
- Atobe Kaori
- Attokaran Antony George
- Attwood Ben
- Auchabie Johann
- Awad Ahmed K.
- Awad Maher
- Ayestaran J. Ignacio
- Azman Abd. Hamid
- Babashev Baurzhan
- Baby Sailaja K.
- Badre Gaëtan
- Baghbanian Reza
- Baig Nadia
- Baikady R. Rao
- Bajaj Manan
- Bakr Lubna
- Banach Dorota
- Barbier François
- Barbier François
- Baronia Arvind
- Barsoum Mina
- Bassetti Matteo
- Batirel Ayse
- Battaglini Denise
- Baudry Thomas
- Baumer Tom
- Bayindir Yasar
- Baykam Nurcan N.
- Bazhykayeva Yelena
- Belkhadir Z.
- Bellina Davide
- Belman Daniel
- Belskiy Vladislav
- Bermudez Rosana Munoz
- Beuzelin M.
- Bhadange Neeraj
- Bilir Yeliz
- Bilkhayr Hala
- Biradar Vishwanath
- Bisanti Alessandra
- Biston Patrick
- Black E.
- Blasco-Navalpotro Miguel Angel
- Bloos Frank
- Bojko Jozef
- Borsi Seyed Hamid
- Bortolotti Perrine
- Bose Payel
- Botelho Isabel
- Bouaziz Mounir
- Bouhuwaish Ahmad
- Boukatta Brahim
- Bourenne Jérémy
- Bourgeois Marc
- Bracht Hendrik
- Bracht Hendrik
- Brajkovic Ana Vujaklija
- Brewster David
- Broda Hanna
- Bruel Cédric
- Bubenek-Turconi Serban
- Buetti Niccolò
- Buimsaedah Ahmad
- Burma Yaroslava
- Cakmak Rumeysa
- Carelli Simone
- Cartoze Nuno
- Casares Vanessa
- Castanera Jérémy
- Castillo Roberto Alejandro
- Catalan Beatriz
- Centeno Pablo
- Cerman Jaroslav
- Ceyhun Solako?lu
- Chaaban Mohammad Karam
- Chandran Jagadish
- Chantziara Vasiliki
- Chatzis Marinos
- Chen Xiaomei
- Chiewroongroj Supattra
- Chikungwa Moses
- Chou Nai-Kuan
- Chukina Maria
- Cia Cong-Tat
- Cobb Katherine
- Cobilinschi Cristian
- Cole Stephen
- Conway Morris Andrew
- Cortegiani Andrea
- Costa Vasco
- Cotoia Antonella
- Coupez Elisabeth
- Covotta Marco
- Cowton Amanda
- Cunha Rui Pedro
- Custovic Aida
- da Costa Tito
- Dabiri Gholamreza
- Dahyot-Fizelier Claire
- Daroui Ivan
- Datta Avijatri
- Davalos-Alvarez Adrian
- De Bus Liesbet
- De Bus Liesbet
- de Figueiredo António Manuel Pereira
- De Geer Lina
- De La Rica Alejandro Suarez
- De Pascale Gennaro
- De Schryver Nicolas
- De Waele Elisabeth
- De Waele Jan
- De Waele Jan
- Demeret Sophie
- Demiray Emine Kubra Dindar
- Dendane Tarek
- Denys Wouter
- Desalu Ibironke
- Dessap Armand Mekonted
- Di Gravio Valentina
- Di Guardo Andrea
- Diab Adei
- Dimopoulos Georges
- Djanikian Flora
- Dolan Rachael
- Dominguez-Cherit Jose G.
- Dsilva Carol
- Duarte Tiago
- Dubler Simon
- Duburcq Thibault
- Dulac Thierry
- Duprey Matthieu
- Dwivedi Jyotsna
- Edin Alicia
- Efthymiou Anna
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbuzidi Abdurahaman
- Elhadi Muhammed
- Elhadidy Amr
- Elmandouh Omar
- Elrabi Omar
- Elsayed Ahmed
- Ercole Ari
- Erdo?an Cem
- Eremenko Aleksandr
- Eroglu Ahmet
- Eroglu Ege
- Erol Çi?dem
- Ersoy Yasemin
- Ersoz Gulden
- Escudier Etienne
- Espina Lorena Forcelledo
- Evik Guliz
- Fares Aya
- Fartoukh Muriel
- Faulkner Maria
- Fernández Rubén
- Ferrer Ricard
- Fildisis Georgios
- Filipescu Daniela Carmen
- Filipovic-Grcic Ina
- Finnis Mackenzie
- Finnis Mackenzie
- Fiorelli Silvia
- Flores Matias
- Fong Kean Khang
- Foucrier Arnaud
- Fourie Cheryl
- Franke Uwe
- Fujitani Shigeki
- Furman Mikhail
- Gaigolnik Denis
- Gainnier Marc
- Gallego Alberto Orejas
- Gamra Marwa
- Garcon Pierre
- Geng Nan
- Georgopoulou Maria
- Ghannam A.
- Ghosh Pralay
- Giacobbe Daniele Roberto
- Goh Ken Junyang
- Goh Qing Yuan
- Goksu Senay
- Gomà Gemma
- Gottschalk Antje
- Goyal Shraddha
- Graham Clive
- Gratarola Angelo
- Grigoras Ioana
- Grintescu Ioana Marina
- Gritsan Alexey
- Guesdon Charlotte
- Guimarães Nádia
- Gundogan Kursat
- Gurjar Mohan
- Gurjar Mohan
- Guzeldag Seda
- Gürbüz Yunus
- Hachimi Abdelhamid
- Haentjens Lionel
- Haibo Qiu
- Hall Daniel
- Hamid Hytham K. S.
- Haney Michael
- Harara Belal
- Hasan Hayat Ben
- Hasan M. Shahnaz
- Hasan Rabab Shaban Ben
- Hasan Rajib
- Hashimoto Satoru
- Hayashi Yoshiro
- Hayashi Yoshiro
- Hdada Aisha Khaled
- Hemead Hanan M.
- Henin Pierre
- Hermosillo Mariana
- Herrera Mara Ocotlan Gonzalez
- Hewer Tayne
- Hoheisen Sandra
- Hollevoet Isabelle
- Homaidan Ahmed Gaber Sadik
- Hosokawa Koji
- Houfi Ashraf El
- Housni Brahim
- Hssain Ali Ait
- Hu Chungfang
- Hu Ting-Yu
- Huang Min
- Hugill Keith
- Humphreys Miss Sally K.
- Huq Shihan Mahmud Redwanul
- Husain A.
- Iasonidou Cristina
- Ibrahim Rebecca
- Idowu Olusola
- Imzi Nadia
- Ippolito Mariachiara
- Islam Mohammad Motiul
- Jackson Matthew
- Jain Nikhilesh
- Jakob Stephan
- Jamaluddin Muhamad Fadhil Hadi
- Janny Sylvie
- Jaramillo CFhavala
- Javaherforoosh Fatemeh
- Jayyab Mustafa Abu
- Jeon Kyeongman
- Jeon Kyeongman
- Jhanji S.
- Jianfeng Xie
- Jobran Rania
- Johnson Aimee
- Kagan Ilya
- Kaimakamis Evangelos
- Kalem Ay?e Kaya
- Kalfon Pierre
- Kaligozhin Zhannur
- Kampolis C.
- Kanjaa Nabil
- Kannan Santhana
- Karaali Ridvan
- Karaiskos Ilias
- Karar Ali Adil Ali
- Karic Edin
- Karmakar Saurabh
- Karumai Toshiyuki
- Kashipazha Davood
- Kato Hideaki
- Kayaaslan Bircan
- Keegan Allison
- Kent Melanie
- Khade Reena
- Kiani Arash
- Kipnis Eric
- Klouche Kada
- Kocagoz Sesin
- Kogkopoulos Evangelos
- Koksal Iftihar
- Komorowska Irmina Kaptur
- Kothari Nikhil
- Kotkowska Anna
- Kouroulas Vasilios
- Koutsoukou Vasiliki
- Kovacevic Pedja
- Krystopchuk Andriy
- Ku Shih-Chi
- Kuo Li-Kuo
- Kuriyama Akira
- Kurt Ibrahim
- Kusoglu Hulya
- Kutsogiannis Demetrios J.
- Kwa Andrea Lay Hoon
- Lance Marcus
- Larcher Romaric
- Lasic Hrvoje
- Laupland Kevin
- Layos Nathalie
- Le Guennec Loïc
- Le Meur Anthony
- Le Souhaitier Mathieu
- Leal Jesús Nicolás Pantoja
- Ledo Sara
- Ledtischke Anne
- Ledtischke Anne
- Lee Sang-Min
- Lefrant Jean-Yves
- Lennard James
- Leone Marc
- Leone Marc
- Lepper Philippe
- Leroy Olivier
- Levin Phillip
- Li Andrew Yunkai
- Lie Sui An
- Liew Mun Thing
- Lim Jia Yan
- Lim Sung Yoon
- Lipman Jeffrey
- Litton Edward
- Lodi Giovanni
- Loftus S.
- Lomeli-Teran Manuel
- Longbottom Rebecca
- Lopez Patricia Mabel
- Louis Guillaume
- Lungu Olguta
- Luo Jili
- Macfie Caroline
- Magomedov Marat
- Mahmoodpoor Ata
- Makino Jun
- Malliotakis Polychronis
- Marchalot A.
- Marcu Alexandra
- Margetts Ben
- Marmanidou Kyriaki
- Marouli Diamantina
- Marques Ana Josefina Pinheiro
- Marsden Nicholas
- Martin-Loeches Ignacio
- Martinez Maria
- Maseda Emilio
- Masjedi Mansoor
- Massri Alexandre
- Matei Mariana Kristina
- Mateu Philippe
- Matsuyoshi Takeo
- Mazlan Mohd Zulfakar
- Mc Cree Melanie
- McCoshen Lorena
- Mcguigan Peter
- Mckee Rachel
- Mehraban Zahra
- Mehtap Selcuk
- Meleshkina Yulia
- Mendes António Carvalho
- Merenkov Yevgeniy
- Mesland Jean-Baptiste
- Metz Carlos
- Meyer Jason
- Mikstacki Adam
- Mingmin Chen
- Mira Jean-Paul
- Mirabella Michele
- Mishima Yuka
- Misra Krushna Chandra
- Misset Benoît
- Moldovan Leora
- Molinos Elena
- Mon Tomas
- Montefiore Pablo
- Montini Luca Maria
- Montravers P.
- Montrucchio Giorgia
- Moorthi P. Dhakshina
- Morris Andrew Conway
- Morris Andrew Conway
- Morvillo Lic Natalia
- Mostafa Tarek
- Mouhssine Doumiri
- Moura José Pedro
- Mugazov Miras
- Mukherjee Sudipta
- Mulhi Randeep
- Muzaffar Syed Nabeel
- Nadeem Rashid
- Nafees Khalid Mahmood Khan
- Nagashima Michio
- Ng Kangqi
- Ng Louis Xiang Long
- Ng Shin Yi
- Nica Alexandru
- Nikolaou Charikleia
- Nikolic Mario
- Nimbolkar Janardan
- Nissar Shaikh
- Noel Cindérella
- Noor Zuraini Md
- Novo Mariana
- Nowakowski Tomasz
- Nuccetelli Yanina
- Nunes Cristina
- Oikonomou Marina
- Oladimeji Motunrayo
- Olatosi John O.
- Omori Koichiro
- Ong Caroline Yu Ming
- Opdenacker Godelive
- Osman Nermin
- Ouhadian Maryam
- Ozair Ahmad
- Ozgen Cansu
- Ozturk Barcin
- Pagani Jl
- Pahuja Madhumati
- Paiva José-Artur
- Palermo Anna Maria
- Papageorgiou Eirini
- Papanikolaou M.
- Papathanakos Georgios
- Papoti Sofia
- Parcell Benjamin J.
- Park Seung Yong
- Park Sunghoon
- Pascoalinho Dulce
- Pasieka Bastian
- Paskalis Harry
- Patel Jamie
- Patel Mayur
- Patrier Juliette
- Paulet Rémi
- Peichota Mariusz
- Peije Li
- Pelagalli Lorella
- Pelosi Paolo
- Pereira Tiago
- Pereira Énio
- Perez-Nieto Orlando R.
- Perrigault Pierre-François
- Persec Jasminka
- Petros Sirak
- Pheng Lee See
- Philippart François
- Pietraszek-Grzywaczewska Iwona
- Pinto Ana Rios
- Pollock Hamish
- Popescu Mihai
- Porcile Elisa
- Povoa Pedro
- Prazak Josef
- Predoi Cornelia Elena
- Prieto Emilio Garcia
- Psallida Vasiliki
- Qian Chuanyun
- Qin Bingyu
- Qiu Haibo
- Quah Jessica Lishan
- Queiró Joana
- Quesada María Dolores
- Rabbani Raihan
- Radonic Radovan
- Raguer Laura
- Rahman Hamizah Bt Abdul
- Raj Ashok
- Ramanan Mahesh
- Rashid Nurhikmahtul Aqilah Haji Abd
- Rashidi Mahboobeh
- Rathod Darshana
- Razazi Keyvan
- Regli Adrian
- Renaud Paul Jean
- Renta Foteini
- Renuka M. K.
- Retselas Ioannis
- Reyes Luis Felipe
- Reyes Luis Felipe
- Rigler Merav
- Rinka Hiroshi
- Ritzema Jenny
- Rizzo Anna Chiara
- Rocca Ricard Ferrer
- Rocco Monica
- Rodriguez Dra M.
- Roger Claire
- Roig Regina
- Rojo Roceld
- Romanou Vasiliki
- Romero-Gonzalez Juan P.
- Roshdy Ashraf
- Rosman Jérémy
- Routledge Matthew
- Rubina Noor Ahmedi
- Ruckly Stéphane
- Saber Ahmed
- Sabetian Golnar
- Saidahmed Elfayadh
- Saito Hiroki
- Sakagianni Aikaterini
- Sakan Sanja
- Sakkalis Anastasios
- Sales Gabriele
- Salgado Dra Maria
- Sallam Hend
- Saltoglu Nese
- Samdani Pratit
- Sanderson Amanda
- Santos Emilio Diaz
- Saracoglu Kemal Tolga
- Sari Ali
- Sarode Vineet
- Sarshad Hakimeh
- Sarton Benjamine
- Savaie Mohsen
- Saxena Manoj
- Schlevenin Maria Grazia
- Schmidt Karsten
- Seddiki Rachid
- Segura Matías
- Sellami Walid
- Serck Nicolas
- Serghini Issam
- Sharma Ankur
- Sharma Priya
- Shekhar Saurav
- Sheshala Kaladhar
- Shigemitsu Hidenobu
- Siami Shidasp
- Siddiqui Suhail Sarwar
- Silva Stein
- Singer Pierre
- Singh Ritu
- Sjövall Fredrik
- Sligl Wendy
- Sligl Wendy
- Smith Tim
- Smonig Roland
- Smyrniotis Dimitrios
- Soar Natalie
- Sokhan Anton
- Soltan Marina
- Soltani Farhad
- Soulountsi Vasiliki
- Souweine Bertrand
- Spahic Dzana
- Sridharan Dhadappa Damodar
- Staiquly Quentin
- Sudhirchandra Shah
- Sungurtekin Hulya
- Svensson Carl Johan
- Szakmany Tamas
- Szczesniak Anna
- Sánchez-Hurtado Luis
- Tabah Alexis
- Tabah Alexis
- Tabatabaei Seyed Mohammad Nasirodin
- Taher Ahmed Sa
- Tajvidi Ramin
- Takaki Shunsuke
- Talan Leyla
- Tamowicz Barbara
- Tatham Kate
- Tejeda-Huezo Brigitte
- Telli Murat
- Temirov Talgat
- Templeton Maie
- Teresa Ana
- Theodorou Vasiliki
- Thomas-Rueddel Daniel
- Thompson Patricia
- Thyrault Martial
- Tilley Rebecca E.
- Timsit Jean-François
- Timsit Jean-François
- Timuroglu Arif
- Tinaslanidis George
- Tizard Kate
- Tomas Ernesto Deloya
- Tomescu Dana
- Tong Lee Kok
- Torlinski Tomasz
- Torre Valentina Della
- Tran Marc
- Tribulev Maksim
- Tunay Burcu
- Turki Olfa
- Tyler Steven
- Ubeda Alejandro
- Ugwu Euphemia Mgbosoro
- Vaidyanathan R.
- Valeanu Liana
- Vanderhaeghen Sofie F. M.
- Vargas Joel
- Vasileiou Maria
- Vera Paula
- Viderman Dmitriy
- Villafuerte Missael Vladimir Espinoza
- Vistovskaya Natala
- Visvalingam Sheshendrasurian
- Voiriot Guillaume
- Wajdi Maazouzi Ahmed
- Walczak-Wieteska Paulina
- Walid Haji Adi Muhamad Ibnu
- Walsham James
- Wang Hao
- Wang Jinfeng
- Wang Ruilan
- Wang Yan
- Wasowska Dominika
- Weeda Elizabeth
- Wei-Hua Lu
- Weifeng Xie
- Weiss Emmanuel
- Wempe Carola
- Wittebole Xavier
- Wong Siong Ling Danny
- Wongsurakiat Phunsup
- Wusi Qiu
- Xu Lei
- Yakubu Saidu Yusuf
- Yamasaki Masaki
- Yan Jing
- Yap Timothy
- Ye Jilu
- Ye Ling
- Yeh Yu Chang
- Yilmaz Mesut
- Yin Chengfen
- Yin Yongjie
- Ymbetzhanov Yerlan
- Yonan Aimee
- Yoshida Hideki
- Younes Oujidi
- Young Meredith
- Zaki Ahmed
- Zand Farid
- Zand Farid
- Zappela N.
- Zargar Mohammad Amin
- Zeggwagh Amine Ali
- Zhang Min
- Zhao Juan
- Zhao Peng
- Zhen Wang
- Zhou Suming
- Zlojutro Biljana
- Zormpa Artemis
- Zubareva Nadezhda
- Zuccaro Francesco
- Åkerlund Joyce
- Çolak Onur
- Çolak Sait
- Ñamendys-Silva Silvio A.
- Ñamendys-Silva Silvio A.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2023
- Field of study
Purpose
In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated with significant mortality. Granular data are required for optimizing management, and developing guidelines and clinical trials.
Methods
We carried out a prospective international cohort study of adult patients (≥ 18 years of age) with HA-BSI treated in intensive care units (ICUs) between June 2019 and February 2021.
Results
2600 patients from 333 ICUs in 52 countries were included. 78% HA-BSI were ICU-acquired. Median Sequential Organ Failure Assessment (SOFA) score was 8 [IQR 5; 11] at HA-BSI diagnosis. Most frequent sources of infection included pneumonia (26.7%) and intravascular catheters (26.4%). Most frequent pathogens were Gram-negative bacteria (59.0%), predominantly Klebsiella spp. (27.9%), Acinetobacter spp. (20.3%), Escherichia coli (15.8%), and Pseudomonas spp. (14.3%). Carbapenem resistance was present in 37.8%, 84.6%, 7.4%, and 33.2%, respectively. Difficult-to-treat resistance (DTR) was present in 23.5% and pan-drug resistance in 1.5%. Antimicrobial therapy was deemed adequate within 24 h for 51.5%. Antimicrobial resistance was associated with longer delays to adequate antimicrobial therapy. Source control was needed in 52.5% but not achieved in 18.2%. Mortality was 37.1%, and only 16.1% had been discharged alive from hospital by day-28.
Conclusions
HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes