255 research outputs found

    Suplai Dosis P dan K Terhadap Laju Pertumbuhan dan Produksi Tanaman Ubi Jalar (Ipomea batatas L.) Varietas Antin 3

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    Pemupukan merupakan salah satu faktor penting dalam budidaya tanaman. Tanaman ubi jalar diketahui sangat respon terhadap pemupukan. Penelitian ini telah dilaksanakan di lahan penelitian Politeknik Negeri Jember pada bulan April sampai Agustus 2017. Tujuan penelitian ini adalah mengetahui pengaruh dosis pupuk P dan K serta interaksinya terhadap laju pertumbuhan dan produksi tanaman ubi jalar varietas Antin 3. Rancangan percobaan yang digunakan adalah Rancangan Acak Kelompok faktorial dengan 3 kali ulangan. Faktor pertama dosis pupuk TSP (P) terdiri dari 3 taraf yaitu : P1 (78 kg/ha), P2 (117 kg/ha) dan P3 (157 kg/ha). Faktor kedua dosis pupuk KCL (K) terdiri dari 3 taraf yaitu : K1 (150 kg/ha), K2 (300 kg/ha) dan K3 (450 kg/ha). Data hasil penelitian dianalisis secara statistik menurut uji F dan uji lanjut DMRT. Faktor tunggal dosis P dan K serta interaksinya memberikan pengaruh yang tidak nyata terhadap parameter jumlah cabang. Faktor tunggal dosis P memberikan pengaruh nyata terhadap parameter laju pertumbuhan tanaman, jumlah umbi per tanaman, panjang umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu P3 dengan dosis TSP 157 kg/ha. Faktor tunggal dosis K memberikan pengaruh nyata terhadap parameter laju pertumbuhan, jumlah umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu K3 dengan dosis 450kg/ha. Interaksi dosis P dan K memberikan pengaruh nyata terhadap parameter bobot umbi total per bedeng. Perlakuan P3K3 yaitu dosis TSP 157 kg/ha + KCl 450 kg/ ha memberikan hasil tertinggi yaitu 7,2 kg/ bedengPemupukan merupakan salah satu faktor penting dalam budidaya tanaman. Tanaman ubi jalar diketahui sangat respon terhadap pemupukan. Penelitian ini telah dilaksanakan di lahan penelitian Politeknik Negeri Jember pada bulan April sampai Agustus 2017. Tujuan penelitian ini adalah mengetahui pengaruh dosis pupuk P dan K serta interaksinya terhadap laju pertumbuhan dan produksi tanaman ubi jalar varietas Antin 3. Rancangan percobaan yang digunakan adalah Rancangan Acak Kelompok faktorial dengan 3 kali ulangan. Faktor pertama dosis pupuk TSP (P) terdiri dari 3 taraf yaitu : P1 (78 kg/ha), P2 (117 kg/ha) dan P3 (157 kg/ha). Faktor kedua dosis pupuk KCL (K) terdiri dari 3 taraf yaitu : K1 (150 kg/ha), K2 (300 kg/ha) dan K3 (450 kg/ha). Data hasil penelitian dianalisis secara statistik menurut uji F dan uji lanjut DMRT. Faktor tunggal dosis P dan K serta interaksinya memberikan pengaruh yang tidak nyata terhadap parameter jumlah cabang. Faktor tunggal dosis P memberikan pengaruh nyata terhadap parameter laju pertumbuhan tanaman, jumlah umbi per tanaman, panjang umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu P3 dengan dosis TSP 157 kg/ha. Faktor tunggal dosis K memberikan pengaruh nyata terhadap parameter laju pertumbuhan, jumlah umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu K3 dengan dosis 450kg/ha. Interaksi dosis P dan K memberikan pengaruh nyata terhadap parameter bobot umbi total per bedeng. Perlakuan P3K3 yaitu dosis TSP 157 kg/ha + KCl 450 kg/ ha memberikan hasil tertinggi yaitu 7,2 kg/ beden

    OPTIMIZATION ROUGHNESS LEVEL OF TURNING FROM ALUMINUM SCRAP SMELTING RESULT USING SAND CASTING METHOD

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    The Production Machinery Workshop at the Sriwijaya State Polytechnic are producing a lot of aluminum scrap left over from turning, where this waste is still thrown away. This will cause pollution to the environment and will be detrimental to the Sriwijaya State Polytechnic workshop. Casting is one way to deal with aluminum scrap, scrap be melted and then reshaped into a practical material that can be reused. The use of sand as a printing medium in recycling scrolls is not recommended because it is less effective and efficient in terms of long-term use. After research has been carried out, the resulting aluminum shaving waste can be reused as practical material provided that the shavings must be separated from other waste such as iron and steel. In the optimization process, the best value is obtained at the spindle speed factor of 900 rpm (A1), then the feeding depth at 0.5 mm (B1), and the feeding speed at 0.08 mm/put.  The Production Machinery Workshop at the Sriwijaya State Polytechnic are producing a lot of aluminum scrap left over from turning, where this waste is still thrown away. This will cause pollution to the environment and will be detrimental to the Sriwijaya State Polytechnic workshop. Casting is one way to deal with aluminum scrap, scrap be melted and then reshaped into a practical material that can be reused. The use of sand as a printing medium in recycling scrolls is not recommended because it is less effective and efficient in terms of long-term use. After research has been carried out, the resulting aluminum shaving waste can be reused as practical material provided that the shavings must be separated from other waste such as iron and steel. In the optimization process, the best value is obtained at the spindle speed factor of 900 rpm (A1), then the feeding depth at 0.5 mm (B1), and the feeding speed at 0.08 mm/put

    The remnants of galaxy formation from a panoramic survey of the region around M31

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    In hierarchical cosmological models, galaxies grow in mass through the continual accretion of smaller ones. The tidal disruption of these systems is expected to result in loosely bound stars surrounding the galaxy, at distances that reach 1010010 - 100 times the radius of the central disk. The number, luminosity and morphology of the relics of this process provide significant clues to galaxy formation history, but obtaining a comprehensive survey of these components is difficult because of their intrinsic faintness and vast extent. Here we report a panoramic survey of the Andromeda galaxy (M31). We detect stars and coherent structures that are almost certainly remnants of dwarf galaxies destroyed by the tidal field of M31. An improved census of their surviving counterparts implies that three-quarters of M31's satellites brighter than MV<6M_V < -6 await discovery. The brightest companion, Triangulum (M33), is surrounded by a stellar structure that provides persuasive evidence for a recent encounter with M31. This panorama of galaxy structure directly confirms the basic tenets of the hierarchical galaxy formation model and reveals the shared history of M31 and M33 in the unceasing build-up of galaxies.Comment: Published in Nature. Supplementary movie available at https://www.astrosci.ca/users/alan/PANDAS/Latest%20news%3A%20movie%20of%20orbit.htm

    Patterns of alcohol drinking and its association with obesity: data from the third national health and nutrition examination survey, 1988–1994

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    BACKGROUND: Recent reports suggest that alcohol use may have a protective effect on obesity. This study explores association between obesity and alcohol consumption in the non-smoking U.S. adult population. METHODS: We analyzed data on a total of 8,236 respondents who participated in the Third National Health and Nutrition Examination Survey. Body mass index (weight-kg/height-m(2)) was derived from measured height and weight data and categorized into: normal weight, overweight, and obese. Alcohol consumption was measured using following measures: history of drinking, binge drinking, quantity of drinks/day, frequency of drinking, and average volume of drinks/week. RESULTS: Mean body mass index in this sample of non-smokers was 26.4 (95% CI: 26.1, 26.7). Approximately 46% of respondents were classified as current drinkers. Current drinkers had lower odds of obesity (Adjusted odds ratio = 0.73, 95% CI: 0.55, 0.97) as compared to non-drinkers. The odds of overweight and obesity were significantly greater among binge drinkers and those consuming four or more drinks/day. However, those who reported drinking one or two drinks per day had 0.46 (95% CI: 0.34, 0.62) and 0.59 (95% CI: 0.41, 0.86) times the odds of obesity, respectively. Similarly, the odds of obesity were significantly lower among those who reported drinking frequently and consuming less than five drinks per week. The association between overweight and other alcohol measures was less pronounced. CONCLUSION: The results suggest further exploring the possible role of moderate alcohol drinking in controlling body weight in adults

    Electrostatic Origins of CO2-Increased Hydrophilicity in Carbonate Reservoirs

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    Injecting CO2 into oil reservoirs appears to be cost-effective and environmentally friendly due to decreasing the use of chemicals and cutting back on the greenhouse gas emission released. However, there is a pressing need for new algorithms to characterize oil/brine/rock system wettability, thus better predict and manage CO2 geological storage and enhanced oil recovery in oil reservoirs. We coupled surface complexation/CO2 and calcite dissolution model, and accurately predicted measured oil-on-calcite contact angles in NaCl and CaCl2 solutions with and without CO2. Contact angles decreased in carbonated water indicating increased hydrophilicity under carbonation. Lowered salinity increased hydrophilicity as did Ca2+. Hydrophilicity correlates with independently calculated oil-calcite electrostatic bridging. The link between the two may be used to better implement CO2 EOR in fields

    Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library

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    Oxygen is a vital requirement for multi-cellular organisms to generate energy and cells have developed multiple compensatory mechanisms to adapt to stressful hypoxic conditions. Such adaptive mechanisms are intricately interconnected with other signaling pathways that regulate cellular functions such as cell growth. However, our understanding of the overall system governing the cellular response to the availability of oxygen remains limited. To identify new genes involved in the response to hypoxic stress, we have performed a genome-wide gene knockdown analysis in human lung carcinoma PC8 cells using an shRNA library carried by a lentiviral vector. The knockdown analysis was performed under both normoxic and hypoxic conditions to identify shRNA sequences enriched or lost in the resulting selected cell populations. Consequently, we identified 56 candidate genes that might contribute to the cellular response to hypoxia. Subsequent individual knockdown of each gene demonstrated that 13 of these have a significant effect upon oxygen-sensitive cell growth. The identification of BCL2L1, which encodes a Bcl-2 family protein that plays a role in cell survival by preventing apoptosis, validates the successful design of our screen. The other selected genes have not previously been directly implicated in the cellular response to hypoxia. Interestingly, hypoxia did not directly enhance the expression of any of the identified genes, suggesting that we have identified a new class of genes that have been missed by conventional gene expression analyses to identify hypoxia response genes. Thus, our genetic screening method using a genome-wide shRNA library and the newly-identified genes represent useful tools to analyze the cellular systems that respond to hypoxic stress

    Is being overweight associated with engagement in self-injurious behaviours in adolescence, or do psychological factors have more “weight”?

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    Introduction The purpose of this study was to examine the prevalence of non-suicidal self-injurious behaviours (NSSI) among healthy weight and overweight adolescents and to examine the role of age, gender, weight status, treatment condition for weight control, and psychological variables (psychopathological symptoms and emotional skills) in the prediction of NSSI. Methods The study had a cross-sectional design, and participants (n = 370) were aged 14-19 years and were divided in three groups: 205 adolescents with normal weight, 82 adolescents from the community with overweight/obesity, and 83 adolescents with overweight/obesity and in outpatient treatment for weight control. Results The prevalence of these behaviours in the overweight community group (25.6 %) and in the overweight clinical group (14.5 %) was similar to their healthy weight peers (19 %). Not attending an outpatient treatment for weight control, higher psychopathology and less ability to regulate emotions predict the presence of NSSI. Conclusion Being overweight is not associated with NSSI, but psychosocial variables such as psychopathology, emotional deregulation and the absence of medical care predict these behaviours.info:eu-repo/semantics/publishedVersio

    Factors affecting recruitment and retention of community health workers in a newborn care intervention in Bangladesh

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    <p>Abstract</p> <p>Background</p> <p>Well-trained and highly motivated community health workers (CHWs) are critical for delivery of many community-based newborn care interventions. High rates of CHW attrition undermine programme effectiveness and potential for implementation at scale. We investigated reasons for high rates of CHW attrition in Sylhet District in north-eastern Bangladesh.</p> <p>Methods</p> <p>Sixty-nine semi-structured questionnaires were administered to CHWs currently working with the project, as well as to those who had left. Process documentation was also carried out to identify project strengths and weaknesses, which included in-depth interviews, focus group discussions, review of project records (i.e. recruitment and resignation), and informal discussion with key project personnel.</p> <p>Results</p> <p>Motivation for becoming a CHW appeared to stem primarily from the desire for self-development, to improve community health, and for utilization of free time. The most common factors cited for continuing as a CHW were financial incentive, feeling needed by the community, and the value of the CHW position in securing future career advancement. Factors contributing to attrition included heavy workload, night visits, working outside of one's home area, familial opposition and dissatisfaction with pay.</p> <p>Conclusions</p> <p>The framework presented illustrates the decision making process women go through when deciding to become, or continue as, a CHW. Factors such as job satisfaction, community valuation of CHW work, and fulfilment of pre-hire expectations all need to be addressed systematically by programs to reduce rates of CHW attrition.</p

    Regulation of Cathepsin G Reduces the Activation of Proinsulin-Reactive T Cells from Type 1 Diabetes Patients

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    Autoantigenic peptides resulting from self-proteins such as proinsulin are important players in the development of type 1 diabetes mellitus (T1D). Self-proteins can be processed by cathepsins (Cats) within endocytic compartments and loaded to major histocompatibility complex (MHC) class II molecules for CD4+ T cell inspection. However, the processing and presentation of proinsulin by antigen-presenting cells (APC) in humans is only partially understood. Here we demonstrate that the processing of proinsulin by B cell or myeloid dendritic cell (mDC1)-derived lysosomal cathepsins resulted in several proinsulin-derived intermediates. These intermediates were similar to those obtained using purified CatG and, to a lesser extent, CatD, S, and V in vitro. Some of these intermediates polarized T cell activation in peripheral blood mononuclear cells (PBMC) from T1D patients indicative for naturally processed T cell epitopes. Furthermore, CatG activity was found to be elevated in PBMC from T1D patients and abrogation of CatG activity resulted in functional inhibition of proinsulin-reactive T cells. Our data suggested the notion that CatG plays a critical role in proinsulin processing and is important in the activation process of diabetogenic T cells

    Multimodal microscopy for automated histologic analysis of prostate cancer

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    <p>Abstract</p> <p>Background</p> <p>Prostate cancer is the single most prevalent cancer in US men whose gold standard of diagnosis is histologic assessment of biopsies. Manual assessment of stained tissue of all biopsies limits speed and accuracy in clinical practice and research of prostate cancer diagnosis. We sought to develop a fully-automated multimodal microscopy method to distinguish cancerous from non-cancerous tissue samples.</p> <p>Methods</p> <p>We recorded chemical data from an unstained tissue microarray (TMA) using Fourier transform infrared (FT-IR) spectroscopic imaging. Using pattern recognition, we identified epithelial cells without user input. We fused the cell type information with the corresponding stained images commonly used in clinical practice. Extracted morphological features, optimized by two-stage feature selection method using a minimum-redundancy-maximal-relevance (mRMR) criterion and sequential floating forward selection (SFFS), were applied to classify tissue samples as cancer or non-cancer.</p> <p>Results</p> <p>We achieved high accuracy (area under ROC curve (AUC) >0.97) in cross-validations on each of two data sets that were stained under different conditions. When the classifier was trained on one data set and tested on the other data set, an AUC value of ~0.95 was observed. In the absence of IR data, the performance of the same classification system dropped for both data sets and between data sets.</p> <p>Conclusions</p> <p>We were able to achieve very effective fusion of the information from two different images that provide very different types of data with different characteristics. The method is entirely transparent to a user and does not involve any adjustment or decision-making based on spectral data. By combining the IR and optical data, we achieved high accurate classification.</p
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