RNASET2 as a tumor antagonizing gene in a melanoma cancer model

The RNASET2 gene, mapped in 6q27, was previously found to exert control of tumorigenesis in an ovarian cancer system. We present here results indicating a similar control in a melanoma cancer model. Thus, this gene is most likely involved in a common general pathway of tumorigenesis. Moreover, its antitumorigenic activity is manifested in vivo but not in vitro, suggesting that this gene belongs to the growing category of tumor antagonizing/malignancy suppressor genes. A possible role of RNASET2 in the activation of a senescence program, whose responsible locus was mapped in the same chromosomal 6q27 region, seems to be inconsistent with our data

Attenuation of Peak Ground Acceleration with Distance of the June 15, 1999, Tehuacán, México, Earthquake

A seismic event of moment magnitude 7.0 struck the central region of Mexico on June 15, 1999 at 15:41 hrs (local time) between the states of Puebla and Oaxaca. The epicenter of the earthquake was located approximately 20 km to the south-southeast of the town of Tehuacán, Puebla and 55 km to the northeast of Huajuapan de León, Oaxaca. A reconnaissance team consisting of a group of researchers from the University of California at Berkeley (UCB) and the Autonomous University of Mexico (UNAM) visited the area and gathered some preliminary information on the geotechnical aspects of this earthquake. This paper briefly presents some key geotechnical observations and then focuses on the attenuation of peak ground acceleration with distance. A total of 29 strong-motion recordings over a variety of geologic site conditions were compiled and used to develop the observed attenuation of the peak ground acceleration (PGA) with distance for the main event. The results obtained were compared with estimations of PGA using North American attenuation relationships

Near-UV optical-cavities n Ga_2O_3 nanowires

In this Letter, we report optical confinement in the near-ultraviolet (near-UV) range in Ga2O3 nanowires (NWs) by distributed Bragg reflector (DBR) nanopatterned cavities. High-contrast DBRs, which act as the end mirrors of the cavities of the desired length, are designed and fabricated by focused ion beam etching. The resonant modes of the cavities are analyzed by micro-photoluminescence measurements, analytical models, and simulations, which show very good agreement between each other. Experimental reflectivities up to 50% are obtained over the 350-410 nm region for the resonances in this wavelength range. Therefore, Ga2O3 NW optical cavities are shown as good candidates for single-material-based near-UV light emitters

SNL evaluation of Gigabit Passive Optical Networks (GPON).

Gigabit Passive Optical Networks (GPON) is a networking technology which offers the potential to provide significant cost savings to Sandia National Laboratories in the area of network operations. However, a large scale GPON deployment requires a significant investment in equipment and infrastructure. Before a large scale GPON system was acquired and built, a small GPON system manufactured by Motorola was acquired and tested. The testing performed was to determine the suitability of GPON for use at SNL. This report documents that testing. This report presents test results of GPON system consisting of Motorola and Juniper equipment. The GPON system was tested in areas of data throughput, video conferencing, VOIP, security, and operations and management. The GPON system performed well in almost all areas. GPON will not meet the needs of the low percentage of users requiring a true 1-10 Gbps network connection. GPON will also most likely not meet the need of some servers requiring dedicated throughput of 1-10 Gbps. Because of that, there will be some legacy network connections that must remain. If these legacy network connections can not be reduced to a bare minimum and possibly consolidated to a few locations, any cost savings gained by switching to GPON will be negated by maintaining two networks. A contract has been recently awarded for new GPON equipment with larger buffers. This equipment should improve performance and further reduce the need for legacy network connections. Because GPON has fewer components than a typical hierarchical network, it should be easier to manage. For the system tested, the management was performed by using the AXSVison client. Access to the client must be tightly controlled, because if client/server communications are compromised, security will be an issue. As with any network, the reliability of individual components will determine overall system reliability. There were no failures with the routers, OLT, or Sun Workstation Management platform. There were however four ONTs that failed. Because of the small sample size of 64, and the fact that some of the ONTs were used units, no conclusions can be made. However, ONT reliability is an area of concern. Access to the fiber plant that GPON requires must be tightly controlled and all changes documented. The undocumented changes that were performed in the GPON test lab demonstrated the need for tight control and documentation. In summary, GPON should be able to meet the needs of most network users at Sandia National Laboratories. Because it supports voice, video, and data, it positions Sandia National Laboratories to deploy these services to the desktop. For the majority of corporate network users at Sandia National Laboratories GPON should be a suitable replacement for the legacy network

Perancangan Game Mobile Bergenre Edukasi Menggunakan Unity

Game berbasis android terus berkembang dari waktu ke waktu, begitu juga dengan game edukasi. Game edukasi bukan hanya sekedar game yang membuang-buang waktu pemain, tetapi dapat menjadi media alternatif dalam kegiatan pembelajaran. Bahkan game edukasi lebih interaktif dan partisipatif dengan memanfaatkan perangkat smartphone. Tujuan dari penelitian ini adalah untuk menghasilkan sebuah mobile game edukasi menggunakan Unity 3D sebagai enginenya dan menggunakan metode Game Development Lyfe Cycle (GDLC) dalam membuat game. Penelitian ini telah menghasilkan rancangan game edukasi pecah balon yang sangat interaktif dan mampu memberikan manfaatkan bagi pemain, baik itu dari sisi rancangannya maupun dari sisi ketersediaan fiturnya. Game edukasi ini memang masih dikategorikan sederhana dan oleh karenanya perlu mempertimbangkan untuk menerapkan teknologi Augmented-Reality (AR) pada game tersebut agar dapat menjadi salah satu media pembelajaran yang interaktif serta dari sisi fitur perlu menambahkan kuis dan materi