187 research outputs found

    Public survey instruments for business administration using social network analysis and big data

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    Purpose: The subject matter of this research is closely intertwined with the scientific discussion about the necessity of developing and implementing practice-oriented means of measuring social well-being taking into account the intensity of contacts between individuals. The aim of the research is to test the toolkit for analyzing social networks and to develop a research algorithm to identify sources of consolidation of public opinion and key agents of influence. The research methodology is based on postulates of sociology, graph theory, social network analysis and cluster analysis. Design/Methodology/Approach: The basis for the empirical research was provided by the data representing the reflection of social media users on the existing image of Russia and its activities in the Arctic, chosen as a model case. Findings: The algorithm allows to estimate the density and intensity of connections between actors, to trace the main channels of formation of public opinion and key agents of influence, to identify implicit patterns and trends, to relate information flows and events with current information causes and news stories for the subsequent formation of a "cleansed" image of the object under study and the key actors with whom this object is associated. Practical Implications: The work contributes to filling the existing gap in the scientific literature, caused by insufficient elaboration of the issues of applying the social network analysis to solve sociological problems. Originality/Value: The work contributes to filling the existing gap in the scientific literature formed as a result of insufficient development of practical issues of using analysis of social networks to solve sociological problems.peer-reviewe

    Стальные плечи -пространство крепче

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    The workenglobes voluminous subject. The author describes organization methods to achieve comprehensive state of Russian society. Modern conflicts are revealed as a result of incompetence of management systems focused on technocratic approach, while humanitarian approaches are mostly ignored. A suggested model supposes introduction of civilitarian order that includes social justice, reasonable sufficiency, equal weightiness. The author argues thatcivilism together with railway development can renew the role of a human for the well-being of the country.Книга, вышедшая в серии «Научная мысль», посвящена исследованию проблем жизнестойкости социальных пространств, роли транспорта (и прежде всего железных дорог) в развитии, обустройстве среды обитания, производственной деятельности человека, освоении новых перспективных территорий, имеющих высокий природный и промышленный потенциал. С этой точки зрения автором особое внимание уделено концепциям ценности жизни на планете, зарождению сервисного пространства как альтернативы современным конфликтным ситуациям на основе модели цивилитарного порядка, критериев равной весомости, разумной достаточности, социальной справедливости. Приводится план возрождения малых железнодорожных станций для сохранения и расширения полузаброшенных в кризисные (переходные) годы малых поселений

    Use of Technogenic Silica Fume and Brown Coal Semi-Coke in the Technology of Silicon Carbide

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    The paper describes thermodynamic experiments to determine the optimal temperature and time modes for the carbide production process from the briquette charge comprising silica fume and brown coal semi-coke, conditions for chemical enriching of silicon carbide, its phase, chemical and granulometric compositions and particle morphology

    E-learning as a modern resource of education

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    E-learning is becoming increasingly popular today. It is being widely implemented not only in educational institutions but in business and industrial enterprises demanding the fastest and the cheapest means of information exchange and communication. This article is dedicated to eliciting of the background factors of successful implementation and favourable environment to develop e-learning programs. It analyses the e-learning teaching process and methods practiced in several countries, including Russia, and empathizes the major issues and problems the national systems of education have had to face recentl

    Features of microbiological diagnosis and choice of selective antibiotic therapy in patients with acute cholecystitis

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    The objective: to improve the results of destructive forms of acute cholecystitis (AC) surgery by the development of antibiotic therapy algorithm and taking into account the severity of the disease according to Tokyo guidelines (2013). Materials and methods: 266 patients having been operated on for AC made up a treatment group and 203 patients - the control one. In 234 treatment group patients microflora’s bacteriological study was carried out and its selective sensitivity to antibiotics was determined. Results and discussion. The AC treatment group patients (n=266) were arranged according to Tokyo guidelines (2013) into 3 grades. Mild course (grade I) consisted of 29 patients (11%), microbiological studies were not conducted. Antibiotic prophylaxis with beta-lactam antibiotics was used. At moderately severe AC (grade II, n = 200, 75%) escalation antibiotic therapy was carried out. At severe disease (grade III, n = 37, 14%) de-escalation antibiotic therapy was performed. Bacteriological studies were conducted in 237 patients with destructive forms of AC, at that 531 microflora isolates were cultured. Intestinal group microorganisms were the most frequently cultured. Beta-lactam antibiotics’ sensitivity was prevailing and constituted 83.3%. The number of suppurations in the treatment group decreased from 9.8% to 4.3%, and mortality rate decreased from 1.48% to 0.75% (

    Government Social Responsibility: Its Essense And Forms

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    The paper presents a socio-philosophical analysis of government social responsibility of the authorities. It contains the explication of this phenomenon from the position of the system approach: the structure of the responsibility of power as a system is disclosed, its elements are described. The social responsibility of power is presented as a construct that presents certain powerful messages, influences the evaluation of political reality by the object of power. A level model of social responsibility is presented in terms of the degree of activity of the subject of power. The criteria for the social responsibility of the authorities within the framework of the power process are presented. The subject of this study is the social responsibility of the authorities as an open system. The work contains an analysis of the mechanisms for realization the construct of social responsibility of the authorities from the standpoint of achieving national interests. The purpose of this work is to explicate the social responsibility of the authorities, to investigate the mechanisms for implementing the construct of responsibility. There is an attempt to determine the content of government social responsibility in different political environments

    Use of Technogenic Silica Fume and Brown Coal Semi-Coke in the Technology of Silicon Carbide

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    The paper describes thermodynamic experiments to determine the optimal temperature and time modes for the carbide production process from the briquette charge comprising silica fume and brown coal semi-coke, conditions for chemical enriching of silicon carbide, its phase, chemical and granulometric compositions and particle morphology

    Late Antiquity: the regional specific nature of intellectual tradition

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    The primary purpose of the study is to investigate the specifics of the intellectual tradition prevailing in some regions of the Late Antique world. For the purpose of a comprehensive review of the problem, the authors focus on wellknown intellectuals of the 5th-6th centuries, representing Gaul (Ausonius, Sidonius, Ennodius et al.), Alexandria (John Philoponus, Hypatia, Sinesius of Cyrene et al.), Africa (Fulgentius, Priscian, Corippus), Isauria (Candidus Isaurus

    Evaluation of the influence of Inosine pranobex on the matrix protein system in patients with chronic viral cervicitis

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    The reproductive potential of both women and men is declining every year. Many factors contribute to the violation of the reproductive function – chemical, physical, mechanical, psychogenic, however, biological factors have the most pronounced effect on reproduction. Chronic viral cervicitis can be not only the cause of infertility and reproductive losses, but also the development of intraepithelial dysplasia, as well as cervical cancer. PVI, as a monoinfection, is quite rare along with HPV. Other UGIs (urogenital infections) act as common routes of transmission and entry gates. The most common association with PVI is herpesvirus infection. An increase in MMP, both systemically and at the local level, may indicate a violation of cell modeling processes, which contributes to the development of autoimmune inflammation with further destruction of the tissues of the reproductive tract. Activation of MMP promotes the release of HSV from the nerve ganglia and reactivation of the infection. Therapy for HPV and HVI (herpes virus infections) are debatable. There is no single standard of treatment, but there are a number of drugs that have antiviral and immunomodulatory effects. Currently, there are no studies on the dynamics of the effect of HPV and HSV infection on the state of MMPs and TIMPs during Inosine pranobex therapy. Objective: to evaluate changes in matrix metalloproteinases 2 and 9 and their tissue inhibitors types 1 and 2 in patients with human papillomavirus and herpes infections after Inosine pranobex therapy. 6 patients with papillomavirus and herpetic infections were examined and treated with drugs containing the active ingredient Inosine pranobex. The levels of MMP-2, MMP-9 and TIMP-1, TIMP-2 in blood serum were determined using specific reagents from R&D Diagnostics Inc. (USA). The dynamics of indicators in the blood serum of patients with PVI showed a decrease in the level of MMP-2, MMP-9, TIMP-1 with a simultaneous increase in TIMP-2 relative to the values before therapy. In patients with PVI and HVI, Inosine pranobex therapy showed a decrease in MMP-2 and MMP-9 levels, no changes in the content of TIMP-1, but an increase in the serum content of TIMP-2. Prior to the use of therapy, an increase in the ratio in the main groups in comparison with the control group was found, however, the largest increase was found in the group with the association of infections. After therapy, positive dynamics was established in the main groups. Thus, the ratio in group I decreased and became equal to the control values. In the II group of patients, the ratio, despite the decrease, remained higher than the control values and higher in comparison with the I group of women

    Indicators of the cytokine system in practically healthy women of different ages and interrelation with the emotional state

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    Numerous studies show the role of the cytokine network in the pathogenesis of anxiety and depression. However, at present, studies of the correlation between the levels of pro-inflammatory and antiinflammatory cytokines and the level of emotional stress are rather few. The aim of the study was to analyze the serum levels of pro-inflammatory and anti-inflammatory cytokines and the emotional state in apparently healthy women depending on age. Serum levels were tested IL-1β, IL-6, IL-17, IFNγ, IL-10 and IL-4 in 100 apparently healthy women, who were divided into 3 groups depending on age (WHO): 18-44 (young age) 30 people, 45-59 (middle age) 40 people, 60-74 (old age) 30 people (sandwich variant of enzyme-linked immunosorbent assay, pg/mL). To assess the emotional component of health, all the subjects passed the questionnaire SF-36 “Assessment of the quality of life”. Statistical processing of the obtained data was carried out using the analytical software IBM SPSS Statistics, 22.0. In practically healthy women, an increase in the values of IL-1β and IL-6 was found in the elderly group (p < 0.05), while no differences were found between the groups of young and middle age. The level of IFNγ in all age groups of women did not differ significantly. At the same time, in the elderly group, the levels of IFNγ in 40% ranged from 1.04 to 8.76 pg/mL, and in 60% of women – from 24.85 to 28.5 pg/mL. IL-17 was also high (p < 0.05-0.01) in the group of women aged 60-74. In the anti-inflammatory link, the opposite picture was observed, for example, in young and middle-aged women, the levels of IL-10 and IL-4 were higher than in the elderly group. Thus, the analysis made it possible to state that the parameters of the cytokine profile and emotional state in women are associated with age
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