Optimal Control and Sensitivity Analysis of a Fractional Order TB Model

A Caputo fractional-order mathematical model for the transmission dynamics of tuberculosis (TB) was recently proposed in [Math. Model. Nat. Phenom. 13 (2018), no. 1, Art. 9]. Here, a sensitivity analysis of that model is done, showing the importance of accuracy of parameter values. A fractional optimal control (FOC) problem is then formulated and solved, with the rate of treatment as the control variable. Finally, a cost-effectiveness analysis is performed to assess the cost and the effectiveness of the control measures during the intervention, showing in which conditions FOC is useful with respect to classical (integer-order) optimal control.Comment: This is a preprint of a paper whose final and definite form is with 'Statistics Opt. Inform. Comput.', Vol. 7, No 2 (2019). See [http://www.IAPress.org]. Submitted 09/Sept/2018; Revised 10/Dec/2018; Accepted 11/Dec/2018. arXiv admin note: text overlap with arXiv:1801.09634, arXiv:1810.0690

Analysis of unmitigated large break loss of coolant accidents using MELCOR code

In the framework of severe accident research activity developed by ENEA, a MELCOR nodalization of a generic Pressurized Water Reactor of 900 MWe has been developed. The aim of this paper is to present the analysis of MELCOR code calculations concerning two independent unmitigated large break loss of coolant accident transients, occurring in the cited type of reactor. In particular, the analysis and comparison between the transients initiated by an unmitigated double-ended cold leg rupture and an unmitigated double-ended hot leg rupture in the loop 1 of the primary cooling system is presented herein. This activity has been performed focusing specifically on the in-vessel phenomenology that characterizes this kind of accidents. The analysis of the thermal-hydraulic transient phenomena and the core degradation phenomena is therefore here presented. The analysis of the calculated data shows the capability of the code to reproduce the phenomena typical of these transients and permits their phenomenological study. A first sequence of main events is here presented and shows that the cold leg break transient results faster than the hot leg break transient because of the position of the break. Further analyses are in progress to quantitatively assess the results of the code nodalization for accident management strategy definition and fission product source term evaluation

Room temperature GW bar detector with opto-mechanical readout

We present the full implementation of a room-temperature gravitational wave bar detector equipped with an opto-mechanical readout. The mechanical vibrations are read by a Fabry--Perot interferometer whose length changes are compared with a stable reference optical cavity by means of a resonant laser. The detector performance is completely characterized in terms of spectral sensitivity and statistical properties of the fluctuations in the system output signal. The new kind of readout technique allows for wide-band detection sensitivity and we can accurately test the model of the coupled oscillators for thermal noise. Our results are very promising in view of cryogenic operation and represent an important step towards significant improvements in the performance of massive gravitational wave detectors.Comment: 7 figures, submitted to Phys. Rev.

HST's view of the youngest massive stars in the Magellanic Clouds

Accurate physical parameters of newborn massive stars are essential ingredients to shed light on their formation, which is still an unsolved problem. The rare class of compact H II regions in the Magellanic Clouds (MCs), termed ``high-excitation blobs'' (HEBs), presents a unique opportunity to acquire this information. These objects (~ 4" to 10", ~ 1 to 3 pc, in diameter) harbor the youngest massive stars of the OB association/molecular cloud complexes in the MCs accessible through high-resolution near-IR and optical techniques. We present a brief overview of the results obtained with HST mainly on two HEBs, one in the LMC (N159-5) and the other in the SMC (N81).Comment: 5 pages, to appear in the Proceedings of the 41st ESLAB Symposium "The Impact of HST on European Astronomy", 29 May to 1 June 2007, ESTEC, Noordwijk, Netherlands; eds. Guido De Marchi and Duccio Macchett