3,574 research outputs found

    Museum pieces? The role and value of national museum libraries in the digital age

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    This thesis examines how national museum libraries are planning to respond over the next decade to the strategic challenges and opportunities they are facing as a result of socio-technological changes that are occurring during the digital age. The study adopts a pragmatic philosophical approach and uses an explanatory sequential mixed-methods research design. The research consists of a two round Delphi survey, which was distributed to two hundred national museum libraries across forty countries, and seven case studies, which were undertaken across five countries. The case studies are comprised of semi-structured interviews with library managers and users, and document analysis of library strategies and policies. The results are presented as thematic conclusions and possible future scenarios. The research shows that many library managers have a clearly defined sense of their libraries' roles, values, and future strategic priorities. However, there is a lack of consensus concerning strategic positioning, with some seeking to augment internal museum support and others aiming to increase public engagement. Collection development is set to remain predominantly print focused, with acquisition of electronic resources likely to develop gradually. This position contrasts with libraries in other sectors, notably academic libraries, where the print to digital change process is typically occurring more rapidly. Similarly, utilisation of digital technologies that support service provision and content delivery will take place in a highly selective and planned manner. Most library users have a positive outlook about their national museum libraries. They particularly value the specialist nature of the collections, the subject knowledge of library staff, and opportunities for scholarly collaboration. However, there are concerns about collection discoverability and library communication. The research findings point towards three possible future scenarios for national museum libraries - internally focused consolidation, externally focused commercialisation, and mixed economy contradistinction. Each offers plausible options for strategic planning over the next decade

    The Ethics of Internet Research

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    Abstract Research conducted on the internet is a cost effective form of recruitment, data collection, and analysis. Researchers can access individuals worldwide for studies in remote areas where there is a lack of or inability to conduct research. With this opportunity come ethical concerns such as determining a safe environment to take a survey, research in a virtual environment, data security, confidentiality, and performing secondary analysis on archived support group information. Researchers should be aware of laws regarding minors and respect the core ethical principles of beneficence, respect for persons and justice. Institutional Review Boards at institutions conducting this type of research need specific guidelines for researchers to follow in order to maintain the integrity of research. It is important for future nurse researchers to incorporate new therapeutic models and specific steps to protect the public when participating in internet research

    Comets, historical records and vedic literature

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    A verse in book I of Rigveda mentions a cosmic tree with rope-like aerial roots held up in the sky. Such an imagery might have ensued from the appearance of a comet having `tree stem' like tail, with branched out portions resembling aerial roots. Interestingly enough, a comet referred to as `heavenly tree' was seen in 162 BC, as reported by old Chinese records. Because of weak surface gravity, cometary appendages may possibly assume strange shapes depending on factors like rotation, structure and composition of the comet as well as solar wind pattern. Varahamihira and Ballala Sena listed several comets having strange forms as reported originally by ancient seers such as Parashara, Vriddha Garga, Narada and Garga. Mahabharata speaks of a mortal king Nahusha who ruled the heavens when Indra, king of gods, went into hiding. Nahusha became luminous and egoistic after absorbing radiance from gods and seers. When he kicked Agastya (southern star Canopus), the latter cursed him to become a serpent and fall from the sky. We posit arguments to surmise that this Mahabharata lore is a mythical recounting of a cometary event wherein a comet crossed Ursa Major, moved southwards with an elongated tail in the direction of Canopus and eventually went out of sight. In order to check whether such a conjecture is feasible, a preliminary list of comets (that could have or did come close to Canopus) drawn from various historical records is presented and discussed.Comment: This work was presented in the International Conference on Oriental Astronomy held at IISER, Pune (India) during November, 201

    An evaluation of seasonal variations in footwear worn by adults with inflammatory arthritis: a cross-sectional observational study using a web-based survey

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    Background: Foot problems are common in adults with inflammatory arthritis and therapeutic footwear can be effective in managing arthritic foot problems. Accessing appropriate footwear has been identified as a major barrier, resulting in poor adherence to treatment plans involving footwear. Indeed, previous New Zealand based studies found that many people with rheumatoid arthritis and gout wore inappropriate footwear. However, these studies were conducted in a single teaching hospital during the New Zealand summer therefore the findings may not be representative of footwear styles worn elsewhere in New Zealand, or reflect the potential influence of seasonal climate changes. The aim of the study was to evaluate seasonal variations in footwear habits of people with inflammatory arthritic conditions in New Zealand. Methods: A cross-sectional study design using a web-based survey. The survey questions were designed to elicit demographic and clinical information, features of importance when choosing footwear and seasonal footwear habits, including questions related to the provision of therapeutic footwear/orthoses and footwear experiences. Results: One-hundred and ninety-seven participants responded who were predominantly women of European descent, aged between 46–65 years old, from the North Island of New Zealand. The majority of participants identified with having either rheumatoid arthritis (35%) and/or osteoarthritis (57%) and 68% reported established disease (>5 years duration). 18% of participants had been issued with therapeutic footwear. Walking and athletic shoes were the most frequently reported footwear type worn regardless of the time of year. In the summer, 42% reported wearing sandals most often. Comfort, fit and support were reported most frequently as the footwear features of greatest importance. Many participants reported difficulties with footwear (63%), getting hot feet in the summer (63%) and the need for a sandal which could accommodate a supportive insole (73%). Conclusions: Athletic and walking shoes were the most popular style of footwear reported regardless of seasonal variation. During the summer season people with inflammatory arthritis may wear sandals more frequently in order to accommodate disease-related foot deformity. Healthcare professionals and researchers should consider seasonal variation when recommending appropriate footwear, or conducting footwear studies in people with inflammatory arthritis, to reduce non-adherence to prescribed footwear

    In silico-guided optimisation of oxygen gradients in hepatic spheroids

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    One of the key advantages of assessing the hepatotoxic potential of xenobiotics in spheroids rather than monolayer cell culture is the existence of a more physiologically relevant testing environment. Three-dimensional cultures support spatial gradients in nutrients such as oxygen that can be exploited to better represent in vivo gradients that exist along a fundamental sub-unit of liver microarchitecture, the liver sinusoid. The physical and physiological processes that result in the establishment of such gradients can be described mathematically. Quantification of the rates governing these processes and optimisation of cell culture conditions can be performed in silico to better inform experimental design. In this study, we take into account cell line-specific physiological properties, spheroid size and the impact of experimental equipment geometries in order to demonstrate how mathematical models can be optimised to achieve specific in vivo-like features in different scenarios. Furthermore, the sensitivity of such optimised gradients is analysed with respect to culture conditions and considerations are given to prevent the emergence of hypoxic regions in the spheroid. The methodology presented provides an enhanced understanding of the mechanisms of the system within this simulated in vitro framework such that experimental design can be more carefully calibrated when conducting experiments using hepatic spheroids. © 2019 Elsevier B.V
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