Eficiência agronômica de nova formulação de inoculante rizobiano para feijão-caupi

O objetivo deste trabalho foi avaliar a eficiência agronômica da formulação polimérica IPC 2.2 como veículo de inoculação para feijão-caupi. Foi avaliada a sobrevivência de células aos 180 dias de armazenamento. Em experimento de campo, comparou-se a formulação polimérica com a turfosa e a líquida e com adubação nitrogenada de 50 e 80 kg ha-¹ de N e um controle absoluto. A formulação IPC 2.2 manteve concentração de células superior a 109 g-1 após 180 dias e, em campo, proporcionou produtividade de grãos superior à do controle absoluto e igual à dos tratamentos nitrogenados e veículos turfoso e líquido

Congenital Zika Virus Infection: Beyond Neonatal Microcephaly

Recent studies have reported an increase in the number of fetuses and neonates with microcephaly whose mothers were infected with the Zika virus (ZIKV) during pregnancy. To our knowledge, most reports to date have focused on select aspects of the maternal or fetal infection and fetal effects. OBJECTIVE To describe the prenatal evolution and perinatal outcomes of 11 neonates who had developmental abnormalities and neurological damage associated with ZIKV infection in Brazil. DESIGN, SETTING, AND PARTICIPANTS We observed 11 infants with congenital ZIKV infection from gestation to 6 months in the state of Paraíba, Brazil. Ten of 11 women included in this study presented with symptoms of ZIKV infection during the first half of pregnancy, and all 11 had laboratory evidence of the infection in several tissues by serology or polymerase chain reaction. Brain damage was confirmed through intrauterine ultrasonography and was complemented by magnetic resonance imaging. Histopathological analysis was performed on the placenta and brain tissue from infants who died. The ZIKV genome was investigated in several tissues and sequenced for further phylogenetic analysis. MAIN OUTCOMES AND MEASURES Description of the major lesions caused by ZIKV congenital infection. RESULTS Of the 11 infants, 7 (63.6%) were female, and the median (SD) maternal age at delivery was 25 (6) years. Three of 11 neonates died, giving a perinatal mortality rate of 27.3%. The median (SD) cephalic perimeter at birth was 31 (3) cm, a value lower than the limit to consider a microcephaly case. In all patients, neurological impairments were identified, including microcephaly, a reduction in cerebral volume, ventriculomegaly, cerebellar hypoplasia, lissencephaly with hydrocephalus, and fetal akinesia deformation sequence (ie, arthrogryposis). Results of limited testing for other causes of microcephaly, such as genetic disorders and viral and bacterial infections, were negative, and the ZIKV genome was found in both maternal and neonatal tissues (eg, amniotic fluid, cord blood, placenta, and brain). Phylogenetic analyses showed an intrahost virus variation with some polymorphisms in envelope genes associated with different tissues. CONCLUSIONS AND RELEVANCE Combined findings from clinical, laboratory, imaging, and pathological examinations provided a more complete picture of the severe damage and developmental abnormalities caused by ZIKV infection than has been previously reported. The term congenital Zika syndrome is preferable to refer to these cases, as microcephaly is just one of the clinical signs of this congenital malformation disorder.73121407141

Analysis of antidiarrhoeic effect of plants used in popular medicine

People customarily use the extracts of plants known to have antidiarrhoeal effects without any scientific base to explain the action of the extract. For this reason, an investigation was undertaken with a view to determining the efficacy of the effects of the brute aqueous extract (BAE) of the leaves of Psidium guajava (guava), Stachytarpheta cayenensis (bastard vervain), Polygonum punctatum (water. smartweed), Eugenia uniflora (Brazil or Surinam cherry) and Aster squamatus (zé-da-silva) on the intestinal transport of water in rats and on the gastrointestinal propulsion in mice. With the exception of the BAE of S. cayenensis, all other BAE's have increased the absorption of water in one or more intestinal portion in relation to the control group. All tested BAE, except that of P. punctatum, reduced the gastrointestinal propulsion in relation to that of the control group. The results indicate that the BAE of the leaves of P. guajava, S. cayenensis, P. punctatum, E. uniflora and A. squamatus have a potential antidiarrhoeic effect to be confirmed by additional investigations in animals infected with enteropathogenic agents.<br>Para combater a diarréia muitas vezes as pessoas utilizam extratos de plantas conhecidas popularmente como anti-diarréicas, mesmo sem base científica. Em razão disto, verificou-se o efeito do extrato aquoso bruto (EAB) das folhas da Psidium guajava (goiabeira), Stachytarpheta cayenensis (gervão), Polygonum punctatum (polígono ou pimenta d'água), Eugenia uniflora (pitangueira) e Aster squamatus (zé-da-silva) no transporte intestinal de água em ratos e na propulsão gastrointestinal em camundongos. Com exceção do EAB de S. cayenensis, os demais aumentaram a absorção de água em uma ou mais porções do intestino em relação ao grupo-controle. Todos os EAB testados, com exceção do P. punctatum, reduziram o trânsito intestinal em relação ao grupo-controle. Com base nos resultados obtidos conclui-se que os EAB das folhas de P. guayava, S. cayenensis, P. punctatum, E. uniflora e A. squamatus têm potencial ação anti-diarréica, a ser confirmada em novas investigações em animais infectados por agentes enteropatogênicos. Palavras-chave