Postural control is not systematically related to reading skills:implications for the assessment of balance as a risk factor for developmental dyslexia

Impaired postural control has been associated with poor reading skills, as well as with lower performance on measures of attention and motor control variables that frequently co-occur with reading difficulties. Measures of balance and motor control have been incorporated into several screening batteries for developmental dyslexia, but it is unclear whether the relationship between such skills and reading manifests as a behavioural continuum across the range of abilities or is restricted to groups of individuals with specific disorder phenotypes. Here were obtained measures of postural control alongside measures of reading, attention and general cognitive skills in a large sample of young adults (n = 100). Postural control was assessed using centre of pressure (CoP) measurements, obtained over 5 different task conditions. Our results indicate an absence of strong statistical relationships between balance measures with either reading, cognitive or attention measures across the sample as a whole. © 2014 Loras et al

WHO 2010 Guidelines for Prevention of Mother-to-Child HIV Transmission in Zimbabwe: Modeling Clinical Outcomes in Infants and Mothers

The Zimbabwean national prevention of mother-to-child HIV transmission (PMTCT) program provided primarily single-dose nevirapine (sdNVP) from 2002-2009 and is currently replacing sdNVP with more effective antiretroviral (ARV) regimens.Published HIV and PMTCT models, with local trial and programmatic data, were used to simulate a cohort of HIV-infected, pregnant/breastfeeding women in Zimbabwe (mean age 24.0 years, mean CD4 451 cells/µL). We compared five PMTCT regimens at a fixed level of PMTCT medication uptake: 1) no antenatal ARVs (comparator); 2) sdNVP; 3) WHO 2010 guidelines using "Option A" (zidovudine during pregnancy/infant NVP during breastfeeding for women without advanced HIV disease; lifelong 3-drug antiretroviral therapy (ART) for women with advanced disease); 4) WHO "Option B" (ART during pregnancy/breastfeeding without advanced disease; lifelong ART with advanced disease); and 5) "Option B+:" lifelong ART for all pregnant/breastfeeding, HIV-infected women. Pediatric (4-6 week and 18-month infection risk, 2-year survival) and maternal (2- and 5-year survival, life expectancy from delivery) outcomes were projected.Eighteen-month pediatric infection risks ranged from 25.8% (no antenatal ARVs) to 10.9% (Options B/B+). Although maternal short-term outcomes (2- and 5-year survival) varied only slightly by regimen, maternal life expectancy was reduced after receipt of sdNVP (13.8 years) or Option B (13.9 years) compared to no antenatal ARVs (14.0 years), Option A (14.0 years), or Option B+ (14.5 years).Replacement of sdNVP with currently recommended regimens for PMTCT (WHO Options A, B, or B+) is necessary to reduce infant HIV infection risk in Zimbabwe. The planned transition to Option A may also improve both pediatric and maternal outcomes

Youth soccer players, 11-14 years: Maturity, size, function, skill and goal orientation

Background: Participants in many youth sports are commonly combined into age groups spanning 2 years. Aim: The study compared variation in size, function, sport-specific skill and goal orientation associated with differences in biological maturity status of youth soccer players within two competitive age groups. Methods: The sample included 159 male soccer players in two competitive age groups, 11-12 years (n=87) and 13-14 years (n=72). Weight, height, sitting height and four skinfolds, four functional capacities, four soccer skills and goal orientation were measured. Skeletal maturity was assessed using the Fels method. Each player was classified as late, on time or early maturing based on the difference between skeletal and chronological ages. ANOVA was used to compare characteristics of players across maturity groups. Results: Late, on time and early maturing boys are represented among 11-12-year-olds, but late maturing boys are under-represented among 13-14-year-olds. Players in each age group advanced in maturity are taller and heavier than those on time and late in skeletal maturity, but players of contrasting maturity status do not differ, with few exceptions, in functional capacities, soccer-specific skills and goal orientation. Conclusion: Variation in body size associated with maturity status in youth soccer players is similar to that for adolescent males in general, but soccer players who vary in maturity status do not differ in functional capacities, soccer-specific skills and goal orientation