Coupled neutronic/thermal-hydraulic hot channel analysis of high power density civil marine SMR cores

Core average power density of standard small modular reactors (SMR) are generally limited to 60–65 MW/m3, which is 40% lower than for a standard civil PWR in order to accommodate better thermal margins. While designing a SMR core for civil marine propulsion systems, it is required to increase its power density to make more attractive for future deployment. However, there are obvious thermal-hydraulic (TH) concerns regarding a high power density (HPD) core, which needs to be satisfied in order to ensure safe operation through accurate prediction of the TH parameters. This paper presents a coupled neutronic/thermal-hydraulic (TH) hot channel analysis of a HPD 375 MWth soluble-boron-free PWR core using 19.25% 235U enriched micro- heterogeneous ThO2-UO2 duplex fuel and 16% 235U enriched homogeneously mixed all-UO2 fuel with a 15 effective full-power-years (EFPY) core life. To perform this analysis the hybrid Monte Carlo reactor physics code MONK is coupled with sub-channel analysis TH code COBRA-EN. This approach is used to investigate the feasibility of different HPD marine PWR concepts and to identify the main TH challenges characterising these designs. To design HPD cores of between 82 and 111 MW/m3, three cases were chosen by optimizing the fuel pin diameter, pin pitch and pitch-to-diameter ratio. These cases have been studied to determine whether TH safety limits are satisfied by evaluating key parameters, such as minimum departure from nucleate boiling ratio, surface heat flux, critical heat flux, cladding inner surface and fuel centreline temperatures, and pressure drop. The results show that it is possible to achieve a core power density of 100 MW/m3 for both the candidate fuels, a ∼50% improvement on the reference design (63 MW/m3), while meeting the target core lifetime of 15 EFPY and remaining within TH limits. The size of the pressure vessel can therefore be reduced substantially and the economic competitiveness of the proposed civil marine PWR reactor core significantly improved

HUBUNGAN DUKUNGAN SUAMI DENGAN PENGGUNAAN KONTRASEPSI IUD PADA WANITA USIA SUBURDI PUSKESMAS KALIREJO KABUPATENPESAWARANTAHUN 2016

Cakupan KB aktif di Propinsi Lampung tahun 2015 proporsi peserta KB yang terbanyak adalah Suntik (39,24%), Pil (31,28%), Implan (13,22%), IUD (10,75%), Kondom (3,41%), MOP (1,05%), dan MOW (0,91%). Study pendahuluan berdasarkan Buku Register KIA Puskesmas Kalirejo peserta KB aktif berjumlah 163, menggunakan KB suntik 72 (44,31%), IUD 33 (19,84%) , pil 30 (18,31%), kondom 17 (10,43%) MOW 7 (4,47%), implan 4 (2,64%) akseptor (Register KIA Puskesmas Kalirejo Pesawaran, 2015). Tujuan penelitian diketahui hubungan dukungan suami dengan penggunaan kontrasepsi IUD pada Wanita Usia Subur di Puskesmas Kalirejo Kabupaten Pesawaran Tahun 2016. Desain penelitian analitik dengan pendekatan cross sectional (potong lintang). Populasi penelitian seluruh Pasangan Usia Subur yang menjadi akseptor KB menurut catatan Rekam Medik KIA Puskesmas Kalirejo Pesawaran bulan Maret 2016 sebanyak 186 orang. Tehnik Sampling menggunakan Simple Random Samplingsebanyak 127 orang. Analisa data untuk menguji hubungan dua variabel kategori digunakan uji statistik “chi kuadrat” (Chi square). Hasil penelitian sebagian besar responden mendapatkan dukungan suami tidak baiksebanyak 72 orang (56,7%).Sebagian besar responden menggunakan alat kontrasepsi Non IUD sebanyak 68 orang (53,5%).Ada hubungan yang signifikan antara dukungan suami dengan penggunaan kontrasepsi IUD pada Wanita Usia Subur di Puskesmas Kalirejo Kabupaten Pesawaran Tahun 2016 (p-value = 0,000, dan OR 4,037). Saran perlu peningkatan penyuluhan kepada para suami tentang keuntungan, kerugian, efektifitas dan kemudahan penggunaan alat kontrasepsi IUD agar para suami mendapatkan informasi yang benar tentang kontrasepsi IUD sehingga PUS memiliki referensi yang cukup dalam menentukan alat kontrasepsi yang cocok dan sesuai dengan kebutuhannya.. Kata Kunci:Dukungan Suami, Penggunaan Kontrasepsi IUD, PU

The Noncommutative Harmonic Oscillator based in Simplectic Representation of Galilei Group

In this work we study symplectic unitary representations for the Galilei group. As a consequence the Schr\"odinger equation is derived in phase space. The formalism is based on the non-commutative structure of the star-product, and using the group theory approach as a guide a physical consistent theory in phase space is constructed. The state is described by a quasi-probability amplitude that is in association with the Wigner function. The 3D harmonic oscillator and the noncommutative oscillator are studied in phase space as an application, and the Wigner function associated to both cases are determined.Comment: 7 pages,no figure

Towards sustainability by aligning operational programmes and sustainable performance measures

© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. In the last decades, sustainable concerns have increasingly gained importance to organizational survival, and Lean/Six Sigma approaches are becoming more and more outstanding in order to improve sustainability performance. This article aims to evaluate the degree of importance of sustainable performance measures of Brazilian organizations and to propose guidelines to achieve sustainability by aligning these measures with operational improvement programmes. Multiple data collection methods were applied as theoretical literature review, questionnaire survey and semi-structured interviews with industry professionals and academic researchers. The findings show that it is the corporate responsibility to focus their efforts on both operational improvement programmes and sustainable initiatives in order to achieve better environmental protection, corporate reputation, quality management, cost performance and suppliers relations, as they are considered to be more important on organizational sustainability

Centro virtual de coordinación del conocimiento en VIH / Sida: experiencia de gestión del conocimiento en políticas en salud

Knowledge management helps to capture and disseminate existing knowledge, creating new knowledge, communication and collaboration between people who have it. Many organizations in Peru which are committed in the fight against HIV-AIDS have contributed to improving society's response to the epidemic; To do this, they have developed various activities and the way they have learned many lessons. However, these had not been systematized much less shared. Network Knowledge Management (RGC) in HIV-AIDS emerges as a community of practice composed of organizations and governmental and non-governmental seeking systematize their best practices effectively and efficiently achieving a collective learning about the achievements and failures in the topic of interest. These experiences are presented on the platform called "Virtual Knowledge Coordination Centre in HIV-AIDS (HIV CVCC)". The National Institute of Health (NIH) in order to meet one of its priorities and research agenda, results of the Concerted Health and contribute to the national policy of modernization of public administration Plan, assumes responsibility for the joint administration and management Peru AIDS Network RGC and HIV CVCC

HIGHLIGHTING INTRACRANIAL-PRESSURE MONITORING IN PATIENTS WITH SEVERE ACUTE BRAIN TRAUMA

Intrcranial pressure (ICP) monitoring was carried out in 100 patients with severe acute brain trauma, primarily by means of a subarachnoid catheter. Statistical associations were evaluated between maximum ICP values and: 1) Glasgow Coma Scale (GCS) scores; 2) findings on computed tomography (CT) scans of the head; and 3) mortality. A significant association was found between low GCS scores (3 to 5) and high ICP levels, as well as between focal lesions on CT scans and elevated ICP. Mortality was significantly higher in patients with ICP > 40 mm Hg than in those;vith ICP less than or equal to 20 mm Hg.533A39039

The role of bisphosphonates in breast cancer: Development of bisphosphonates

Bisphosphonates are synthetic compounds characterized by a P–C–P group, and are thus analogs of inorganic pyrophosphate. They are used in medicine mainly to inhibit bone resorption in diseases like osteoporosis, Paget's disease and tumor bone disease. They have been used for over a century in industry, and only in 1968 was it shown that bisphosphonates have biological effects. These effects consist mainly of an inhibition of bone resorption and, when given in large amounts, an inhibition of ectopic and normal calcification. While the latter effect is the consequence of a physical-chemical inhibition of calcium phosphate crystal formation, the former is due to a cellular effect involving both apoptosis of the osteoclasts and a destruction of the osteoclastic cytoskeleton, inducing a decrease in osteoclast activity. The biochemical basis of these effects for the nitrogen-containing compounds is an inhibition of the mevalonate pathway caused by the inhibition of farnesylpyrophosphate synthase, which leads to a decrease of the formation of isoprenoid lipids such as farnesylpyrophosphate and geranylgeranylpyrophosphate. The other bisphosphonates are incorporated into the phosphate chain of ATP-containing compounds so that they become non-hydrolyzable. The new P–C–P-containing ATP analogs inhibit cell function and may lead to apoptosis and death of osteoclasts

Centro virtual de coordinación del conocimiento en VIH / Sida: experiencia de gestión del conocimiento en políticas en salud

Knowledge management helps to capture and disseminate existing knowledge, creating new knowledge, communication and collaboration between people who have it. Many organizations in Peru which are committed in the fight against HIV-AIDS have contributed to improving society's response to the epidemic; To do this, they have developed various activities and the way they have learned many lessons. However, these had not been systematized much less shared. Network Knowledge Management (RGC) in HIV-AIDS emerges as a community of practice composed of organizations and governmental and non-governmental seeking systematize their best practices effectively and efficiently achieving a collective learning about the achievements and failures in the topic of interest. These experiences are presented on the platform called "Virtual Knowledge Coordination Centre in HIV-AIDS (HIV CVCC)". The National Institute of Health (NIH) in order to meet one of its priorities and research agenda, results of the Concerted Health and contribute to the national policy of modernization of public administration Plan, assumes responsibility for the joint administration and management Peru AIDS Network RGC and HIV CVCC