1,122 research outputs found

    Two-field cosmological models and large-scale cosmic magnetic fields

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    We consider two different toy cosmological models based on two fields (one normal scalar and one phantom) realizing the same evolution of the Bang-to-Rip type. One of the fields (pseudoscalar) interacts with the magnetic field breaking the conformal invariance of the latter. The effects of the amplification of cosmic magnetic fields are studied and it is shown that the presence of such effects can discriminate between different cosmological models realizing the same global evolution of the universe.Comment: 12 pages, 3 figure

    Kinin-B1 receptors in ischaemia-induced pancreatitis: Functional importance and cellular localisation

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    In this study we compare the role of kininB1 and B2 receptors during ischaemia/reperfusion of rat pancreas. Our investigations were prompted by the observation that infusion of a kininB2 receptor antagonist produced significant improvement in acute experimental pancreatitis. In an acute model with two hours of ischaemia/two hours of reperfusion, application of the kininB1 receptor antagonist (CP-0298) alone, or in combination with kininB2 receptor antagonist (CP-0597), significantly reduced the number of adherent leukocytes in postcapillary venules. In a chronic model with five days of reperfusion, the continuous application of kininB1 receptor antagonist or a combination of kininB1 and B2 receptor antagonists markedly reduced the survival rate. In kininreceptor binding studies kininB1 receptor showed a 22-fold increase in expression during the time of ischaemia/ reperfusion. Carboxypeptidase M activity was upregulated 10-fold following two hours of ischaemia and two hours of reperfusion, provided the appropriate specific ligand, desArg10-kallidin and/or desArg9-bradykinin, was used. The occurrence of kininB1 receptor binding sites on acinar cell membranes was demonstrated by microautoradiography. With a specific antibody, the localisation of kininB1 receptor protein was confirmed at the same sites. In conclusion, we have demonstrated the upregulation of the pancreatic acinar cell kininB1 receptors during ischaemia/reperfusion. The novel functional finding was that antagonism of the kininB1 receptors decreased the survival rate in an experimental model of pancreatitis

    On knottings in the physical Hilbert space of LQG as given by the EPRL model

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    We consider the EPRL spin foam amplitude for arbitrary embedded two-complexes. Choosing a definition of the face- and edge amplitudes which lead to spin foam amplitudes invariant under trivial subdivisions, we investigate invariance properties of the amplitude under consistent deformations, which are deformations of the embedded two-complex where faces are allowed to pass through each other in a controlled way. Using this surprising invariance, we are able to show that in the physical Hilbert space as defined by the sum over all spin foams contains no knotting classes of graphs anymore.Comment: 22 pages, 14 figure
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