4,289 research outputs found
Evaporation induced flow inside circular wells
Flow field and height averaged radial velocity inside a droplet evaporating
in an open circular well were calculated for different modes of liquid
evaporation.Comment: 5 page, 3 figures, submitted to European Physical Journal
Halfvortices in flat nanomagnets
We discuss a new type of topological defect in XY systems where the O(2)
symmetry is broken in the presence of a boundary. Of particular interest is the
appearance of such defects in nanomagnets with a planar geometry. They are
manifested as kinks of magnetization along the edge and can be viewed as
halfvortices with winding numbers \pm 1/2. We argue that halfvortices play a
role equally important to that of ordinary vortices in the statics and dynamics
of flat nanomagnets. Domain walls found in experiments and numerical
simulations are composite objects containing two or more of these elementary
defects. We also discuss a closely related system: the two-dimensional smectic
liquid crystal films with planar boundary condition.Comment: 7 pages, 8 figures, To appear as a chapter in Les Houches summer
school on Quantum Magnetis
Synchronized dynamics of cortical neurons with time-delay feedback
The dynamics of three mutually coupled cortical neurons with time delays in
the coupling are explored numerically and analytically. The neurons are coupled
in a line, with the middle neuron sending a somewhat stronger projection to the
outer neurons than the feedback it receives, to model for instance the relay of
a signal from primary to higher cortical areas. For a given coupling
architecture, the delays introduce correlations in the time series at the
time-scale of the delay. It was found that the middle neuron leads the outer
ones by the delay time, while the outer neurons are synchronized with zero lag
times. Synchronization is found to be highly dependent on the synaptic time
constant, with faster synapses increasing both the degree of synchronization
and the firing rate. Analysis shows that presynaptic input during the
interspike interval stabilizes the synchronous state, even for arbitrarily weak
coupling, and independent of the initial phase. The finding may be of
significance to synchronization of large groups of cells in the cortex that are
spatially distanced from each other.Comment: 21 pages, 11 figure
Position paper on the use of mandibular advancement devices in adults with sleep-related breathing disorders: A position paper of the German Society of Dental Sleep Medicine (Deutsche Gesellschaft Zahnaerztliche Schlafmedizin, DGZS)
Custom-made mandibular advancement devices are an effective treatment option for snoring, upper airway resistance syndrome, and obstructive sleep apnea (OSA). Evidence-based data indicates their efficacy, and international sleep societies recommend oral appliance (OA) therapy for patients with sleep-related breathing disorders. The following position paper by the German Society of Dental Sleep Medicine (DGZS) is to guide the interdisciplinary team (sleep physician and sleep disorder dentist) in detail when to prescribe oral appliances. This position paper supports the responsible use of OA as an effective treatment option for patients with sleep-related breathing disorders. The paper advises of proper indication regarding OSA severity, body mass index (BMI), and dentition. It emphasizes the interdisciplinary approach of oral appliance therapy and suggests treatment under the guidance of dentists trained in dental sleep medicine
Boundaries of Disk-like Self-affine Tiles
Let be a disk-like self-affine tile generated by an
integral expanding matrix and a consecutive collinear digit set , and let be the characteristic polynomial of . In the
paper, we identify the boundary with a sofic system by
constructing a neighbor graph and derive equivalent conditions for the pair
to be a number system. Moreover, by using the graph-directed
construction and a device of pseudo-norm , we find the generalized
Hausdorff dimension where
is the spectral radius of certain contact matrix . Especially,
when is a similarity, we obtain the standard Hausdorff dimension where is the largest positive zero of
the cubic polynomial , which is simpler than
the known result.Comment: 26 pages, 11 figure
On mean and seasonal currents and transports at the western boundary of the equatorial Atlantic
Current measurements from two consecutive yearlong deployments of three moored stations at the western end of the equator in the Atlantic, along 44°W, are used to determine the northwestward flow of warm water in the upper several 100 m and of the southeastward counterflow of North Atlantic Deep Water (NADW). Measurements from three acoustic Doppler current profilers (ADCPs) looking upward from 300 m toward the surface allowed calculation of a time series of upper layer transports over 1 year. Mean transport through the array for the upper 300 m is 23.8 Sv with an annual cycle of only ±3 Sv that has its maximum in June-August and minimum in northern spring. Estimated additional mean northwestward transport in the range 300–600 m is 6.7 Sv, based on moored data and shipboard Pegasus and lowered ADCP profiling. In the depth range 1400–3100 m a current core with maximum annual mean southeastward speed of 30 cm s−1 is found along the continental slope that carries an estimated upper NADW transport of 14.2–17.3 Sv, depending on the extrapolation used between the mooring in the core and the continental slope. This transport is higher than off-equatorial estimates and suggests near-equatorial recirculation at the upper NADW level, in agreement with northwestward mean flow found about 140 km offshore. Below 3100 m and above the 1.8°C isotherm, only a small core of lower NADW flow with speeds of 10–15 cm s−1 is found over the flat part of the basin near 1.5°N, clearly separated from the continental slope by a zone of near-zero mean speeds. Estimated transport of that small current core is about 4.5 Sv, which is significantly below other estimates of near-equatorial transport of lower NADW and suggests that a major fraction of lower NADW may cross the 44°W meridian north of the Ceara Rise. Intraseasonal variability is large, although smaller than observed at 8°N near the western boundary. It occurs at a period of about 1 month when it is dominant in the near-surface records and corresponds to earlier observations in the equatorial zones of all oceans and at a period of about 2 months when it is dominant at the NADW level and could be imported either from the north along the boundary or from the east along the equator. The existence of an annual cycle in the deep currents of a few centimeters per second amplitude, as suggested by high-resolution numerical model results, could neither be proven nor disproven because of the high amount of shorter-period variability
S-COL: A Copernican turn for the development of flexibly reusable collaboration scripts
Collaboration scripts are usually implemented as parts of a particular collaborative-learning platform. Therefore, scripts of demonstrated effectiveness are hardly used with learning platforms at other sites, and replication studies are rare. The approach of a platform-independent description language for scripts that allows for easy implementation of the same script on different platforms has not succeeded yet in making the transfer of scripts feasible. We present an alternative solution that treats the problem as a special case of providing support on top of diverse Web pages: In this case, the challenge is to trigger support based on the recognition of a Web page as belonging to a specific type of functionally equivalent pages such as the search query form or the results page of a search engine. The solution suggested has been implemented by means of a tool called S-COL (Scripting for Collaborative Online Learning) and allows for the sustainable development of scripts and scaffolds that can be used with a broad variety of content and platforms. The tool’s functions are described. In order to demonstrate the feasibility and ease of script reuse with S-COL, we describe the flexible re-implementation of a collaboration script for argumentation in S-COL and its adaptation to different learning platforms. To demonstrate that a collaboration script implemented in S-COL can actually foster learning, an empirical study about the effects of a specific script for collaborative online search on learning activities is presented. The further potentials and the limitations of the S-COL approach are discussed
Evaluation of a Bayesian inference network for ligand-based virtual screening
Background
Bayesian inference networks enable the computation of the probability that an event will occur. They have been used previously to rank textual documents in order of decreasing relevance to a user-defined query. Here, we modify the approach to enable a Bayesian inference network to be used for chemical similarity searching, where a database is ranked in order of decreasing probability of bioactivity.
Results
Bayesian inference networks were implemented using two different types of network and four different types of belief function. Experiments with the MDDR and WOMBAT databases show that a Bayesian inference network can be used to provide effective ligand-based screening, especially when the active molecules being sought have a high degree of structural homogeneity; in such cases, the network substantially out-performs a conventional, Tanimoto-based similarity searching system. However, the effectiveness of the network is much less when structurally heterogeneous sets of actives are being sought.
Conclusion
A Bayesian inference network provides an interesting alternative to existing tools for ligand-based virtual screening
Functional renormalization group with a compactly supported smooth regulator function
The functional renormalization group equation with a compactly supported
smooth (CSS) regulator function is considered. It is demonstrated that in an
appropriate limit the CSS regulator recovers the optimized one and it has
derivatives of all orders. The more generalized form of the CSS regulator is
shown to reduce to all major type of regulator functions (exponential,
power-law) in appropriate limits. The CSS regulator function is tested by
studying the critical behavior of the bosonized two-dimensional quantum
electrodynamics in the local potential approximation and the sine-Gordon scalar
theory for d<2 dimensions beyond the local potential approximation. It is shown
that a similar smoothing problem in nuclear physics has already been solved by
introducing the so called Salamon-Vertse potential which can be related to the
CSS regulator.Comment: JHEP style, 11 pages, 2 figures, proofs corrected, accepted for
publication by JHE
- …