Studi Living Qur’an Terhadap Dzikir Asma’ul Husna di MAajelis Ta’lim At-Tadzkir Palembang

This article was inspired by the special way that the congregation did in practicing the dhikr of Asmaul Husna. This study aims to determine the effect of the dhikr of Asmaul Huna for the congregation of the At-Tadzkir Ta'lim Council, as well as the understanding of the congregation of the dhikr. At the same time, to find out the features contained in the dhikr of Asmaul Husna, so that the assembly members are motivated to practice it. This type of research is field research. Sources of data used are primary data sources and secondary data. Primary data are interviews with active worshipers in weekly studies at the at-tadzkir ta'lim assembly. As for secondary data, namely supporting primary data literature, this data relates to other parties or sources such as books, magazines, journals, articles, theses, internet, and research results. Furthermore, the data were analyzed using a qualitative descriptive method.Based on the results of the study, it can be concluded that the dhikr of Asmaul Husna can provide changes for those who practice it. Dhikr Asmaul Husna has been around for a long time, but not many people practice it directly. Therefore, the congregation of the at-tadzkir ta'lim assemblies practice it and tend to never leave it to get the virtue and blessing of the dhikr. &nbsp

An Unusual Cause of Seizure in Clinical Practice

Neurocysticercosis (NCC), the infection caused by the larval stage of the tapeworm Taenia solium, is the most common parasitic disease of the nervous system (NS) in humans, where it is the leading cause of late-onset seizures in the endemic areas. Fortunately it is still rare in Bangladesh due to some religious binding in eating pork. Here we present a young man who came to us with Neurocysticercosis as the cause of recurrent seizure and various neurological manifestations

Predicting Hospital Readmission for Campylobacteriosis from Electronic Health Records: A Machine Learning and Text Mining Perspective

(1) Background: This study investigates influential risk factors for predicting 30-day readmission to hospital for Campylobacter infections (CI). (2) Methods: We linked general practitioner and hospital admission records of 13,006 patients with CI in Wales (1990−2015). An approach called TF-zR (term frequency-zRelevance) technique was presented to evaluates how relevant a clinical term is to a patient in a cohort characterized by coded health records. The zR is a supervised term-weighting metric to assign weight to a term based on relative frequencies of the term across different classes. Cost-sensitive classifier with swarm optimization and weighted subset learning was integrated to identify influential clinical signals as predictors and optimal model for readmission prediction. (3) Results: From a pool of up to 17,506 variables, 33 most predictive factors were identified, including age, gender, Townsend deprivation quintiles, comorbidities, medications, and procedures. The predictive model predicted readmission with 73% sensitivity and 54% specificity. Variables associated with readmission included male gender, recurrent tonsillitis, non-healing open wounds, operation for in-gown toenails. Cystitis, paracetamol/codeine use, age (21−25), and heliclear triple pack use, were associated with a lower risk of readmission. (4) Conclusions: This study gives a profile of clustered variables that are predictive of readmission associated with campylobacteriosis

Outcomes following the surgical management of left ventricular outflow tract obstruction; A systematic review and meta-analysis

BACKGROUND: Left ventricular outflow tract obstruction (LVOTO) causes exertional symptoms in two thirds of patients with hypertrophic cardiomyopathy (HCM). Consensus guidelines recommend surgical intervention in patients with drug refractory symptoms. The primary aim of this study was to perform a systematic review and meta-analysis to determine morbidity and mortality after surgery. METHODS: Study Selection: Studies reporting outcomes following surgical intervention for symptomatic LVOTO in HCM. RESULTS: 85 studies were included in the systematic review and 35 studies in the meta-analysis. Contemporary early (30 days) mortality following septal myectomy were 1.4% (CI 0.8, 2.4) I^{2} 9.0%, p = 0.36 and 0.7% (CI 0.3, 1.2) I^{2} 70.7%, p < 0.05 respectively. Sixty-eight studies (80%) reported perioperative complications. The contemporary rate of a perioperative ventricular septal defect was 1.4% (0.8, 2.3) I^{2} 0%, p < 0.05. Late morbidities including atrial fibrillation, stroke, heart failure and transplant were reported in fewer than 22% of studies and few studies compared mortality and clinical outcomes using different surgical approaches to LVOTO. The incidence rate (IR) of reintervention with a further surgical procedure was 0.3% (CI 0.2, 0.4) I^{2} 52.5%, p < 0.05. CONCLUSIONS: Contemporary surgical management of LVOTO is associated with low operative mortality rates but further studies are needed to investigate the impact of surgical therapy on non-fatal early and late complications

Optimization of physical factors affecting the production of thermo-stable organic solvent-tolerant protease from a newly isolated halo tolerant Bacillus subtilis strain Rand

<p>Abstract</p> <p>Background</p> <p>Many researchers have reported on the optimization of protease production; nevertheless, only a few have reported on the optimization of the production of organic solvent-tolerant proteases. Ironically, none has reported on thermostable organic solvent-tolerant protease to date. The aim of this study was to isolate the thermostable organic solvent-tolerant protease and identify the culture conditions which support its production. The bacteria of genus <it>Bacillus </it>are active producers of extra-cellular proteases, and the thermostability of enzyme production by <it>Bacillus </it>species has been well-studied by a number of researchers. In the present study, the <it>Bacillus subtilis </it>strain Rand was isolated from the contaminated soil found in Port Dickson, Malaysia.</p> <p>Results</p> <p>A thermostable organic solvent-tolerant protease producer had been identified as <it>Bacillus subtilis </it>strain Rand, based on the 16S rRNA analysis conducted, as well as the morphological characteristics and biochemical properties. The production of the thermostable organic solvent-tolerant protease was optimized by varying various physical culture conditions. Inoculation with 5.0% (v/v) of (AB₆₀₀= 0.5) inoculum size, in a culture medium (pH 7.0) and incubated for 24 h at 37°C with 200 rpm shaking, was the best culture condition which resulted in the maximum growth and production of protease (444.7 U/ml; 4042.4 U/mg). The Rand protease was not only stable in the presence of organic solvents, but it also exhibited a higher activity than in the absence of organic solvent, except for pyridine which inhibited the protease activity. The enzyme retained 100, 99 and 80% of its initial activity, after the heat treatment for 30 min at 50, 55, and 60°C, respectively.</p> <p>Conclusion</p> <p>Strain Rand has been found to be able to secrete extra-cellular thermostable organic solvent-tolerant protease into the culture medium. The protease exhibited a remarkable stability towards temperature and organic solvent. This unique property makes it attractive and useful to be used in industrial applications.</p

A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins.

The Na+/H+ exchanger regulatory factor (NHERF) binds to the tail of the beta2-adrenergic receptor and plays a role in adrenergic regulation of Na+/H+ exchange. NHERF contains two PDZ domains, the first of which is required for its interaction with the beta2 receptor. Mutagenesis studies of the beta2 receptor tail revealed that the optimal C-terminal motif for binding to the first PDZ domain of NHERF is D-S/T-x-L, a motif distinct from those recognized by other PDZ domains. The first PDZ domain of NHERF-2, a protein that is 52% identical to NHERF and also known as E3KARP, SIP-1, and TKA-1, exhibits binding preferences very similar to those of the first PDZ domain of NHERF. The delineation of the preferred binding motif for the first PDZ domain of the NHERF family of proteins allows for predictions for other proteins that may interact with NHERF or NHERF-2. For example, as would be predicted from the beta2 receptor tail mutagenesis studies, NHERF binds to the tail of the purinergic P2Y1 receptor, a seven-transmembrane receptor with an intracellular C-terminal tail ending in D-T-S-L. NHERF also binds to the tail of the cystic fibrosis transmembrane conductance regulator, which ends in D-T-R-L. Because the preferred binding motif of the first PDZ domain of the NHERF family of proteins is found at the C termini of a variety of intracellular proteins, NHERF and NHERF-2 may be multifunctional adaptor proteins involved in many previously unsuspected aspects of intracellular signaling

Anterior Cervical Infection: Presentation and Incidence of an Uncommon Postoperative Complication.

STUDY DESIGN: Retrospective multi-institutional case series. OBJECTIVE: The anterior cervical discectomy and fusion (ACDF) affords the surgeon the flexibility to treat a variety of cervical pathologies, with the majority being for degenerative and traumatic indications. Limited data in the literature describe the presentation and true incidence of postoperative surgical site infections. METHODS: A retrospective multicenter case series study was conducted involving 21 high-volume surgical centers from the AOSpine North America Clinical Research Network, selected for their excellence in spine care and clinical research infrastructure and experience. Medical records for 17 625 patients who received cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, inclusive, were reviewed to identify the occurrence of 21 predefined treatment complications. Patients who underwent an ACDF were identified in the database and reviewed for the occurrence of postoperative anterior cervical infections. RESULTS: A total of 8887 patients were identified from a retrospective database analysis of 21 centers providing data for postoperative anterior cervical infections (17/21, 81% response rate). A total of 6 postoperative infections after ACDF were identified for a mean rate of 0.07% (range 0% to 0.39%). The mean age of patients identified was 57.5 (SD = 11.6, 66.7% female). The mean body mass index was 22.02. Of the total infections, half were smokers (n = 3). Two patients presented with myelopathy, and 3 patients presented with radiculopathic-type complaints. The mean length of stay was 4.7 days. All patients were treated aggressively with surgery for management of this complication, with improvement in all patients. There were no mortalities. CONCLUSION: The incidence of postoperative infection in ACDF is exceedingly low. The management has historically been urgent irrigation and debridement of the surgical site. However, due to the rarity of this occurrence, guidance for management is limited to retrospective series

Suplai Dosis P dan K Terhadap Laju Pertumbuhan dan Produksi Tanaman Ubi Jalar (Ipomea batatas L.) Varietas Antin 3

Pemupukan merupakan salah satu faktor penting dalam budidaya tanaman. Tanaman ubi jalar diketahui sangat respon terhadap pemupukan. Penelitian ini telah dilaksanakan di lahan penelitian Politeknik Negeri Jember pada bulan April sampai Agustus 2017. Tujuan penelitian ini adalah mengetahui pengaruh dosis pupuk P dan K serta interaksinya terhadap laju pertumbuhan dan produksi tanaman ubi jalar varietas Antin 3. Rancangan percobaan yang digunakan adalah Rancangan Acak Kelompok faktorial dengan 3 kali ulangan. Faktor pertama dosis pupuk TSP (P) terdiri dari 3 taraf yaitu : P1 (78 kg/ha), P2 (117 kg/ha) dan P3 (157 kg/ha). Faktor kedua dosis pupuk KCL (K) terdiri dari 3 taraf yaitu : K1 (150 kg/ha), K2 (300 kg/ha) dan K3 (450 kg/ha). Data hasil penelitian dianalisis secara statistik menurut uji F dan uji lanjut DMRT. Faktor tunggal dosis P dan K serta interaksinya memberikan pengaruh yang tidak nyata terhadap parameter jumlah cabang. Faktor tunggal dosis P memberikan pengaruh nyata terhadap parameter laju pertumbuhan tanaman, jumlah umbi per tanaman, panjang umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu P3 dengan dosis TSP 157 kg/ha. Faktor tunggal dosis K memberikan pengaruh nyata terhadap parameter laju pertumbuhan, jumlah umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu K3 dengan dosis 450kg/ha. Interaksi dosis P dan K memberikan pengaruh nyata terhadap parameter bobot umbi total per bedeng. Perlakuan P3K3 yaitu dosis TSP 157 kg/ha + KCl 450 kg/ ha memberikan hasil tertinggi yaitu 7,2 kg/ bedengPemupukan merupakan salah satu faktor penting dalam budidaya tanaman. Tanaman ubi jalar diketahui sangat respon terhadap pemupukan. Penelitian ini telah dilaksanakan di lahan penelitian Politeknik Negeri Jember pada bulan April sampai Agustus 2017. Tujuan penelitian ini adalah mengetahui pengaruh dosis pupuk P dan K serta interaksinya terhadap laju pertumbuhan dan produksi tanaman ubi jalar varietas Antin 3. Rancangan percobaan yang digunakan adalah Rancangan Acak Kelompok faktorial dengan 3 kali ulangan. Faktor pertama dosis pupuk TSP (P) terdiri dari 3 taraf yaitu : P1 (78 kg/ha), P2 (117 kg/ha) dan P3 (157 kg/ha). Faktor kedua dosis pupuk KCL (K) terdiri dari 3 taraf yaitu : K1 (150 kg/ha), K2 (300 kg/ha) dan K3 (450 kg/ha). Data hasil penelitian dianalisis secara statistik menurut uji F dan uji lanjut DMRT. Faktor tunggal dosis P dan K serta interaksinya memberikan pengaruh yang tidak nyata terhadap parameter jumlah cabang. Faktor tunggal dosis P memberikan pengaruh nyata terhadap parameter laju pertumbuhan tanaman, jumlah umbi per tanaman, panjang umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu P3 dengan dosis TSP 157 kg/ha. Faktor tunggal dosis K memberikan pengaruh nyata terhadap parameter laju pertumbuhan, jumlah umbi per tanaman dan bobot umbi total per tanaman. Perlakuan terbaik yaitu K3 dengan dosis 450kg/ha. Interaksi dosis P dan K memberikan pengaruh nyata terhadap parameter bobot umbi total per bedeng. Perlakuan P3K3 yaitu dosis TSP 157 kg/ha + KCl 450 kg/ ha memberikan hasil tertinggi yaitu 7,2 kg/ beden

Misplaced Cervical Screws Requiring Reoperation.

STUDY DESIGN: A multicenter, retrospective case series. OBJECTIVE: In the past several years, screw fixation of the cervical spine has become commonplace. For the most part, this is a safe, low-risk procedure. While rare, screw backout or misplaced screws can lead to morbidity and increased costs. We report our experiences with this uncommon complication. METHODS: A multicenter, retrospective case series was undertaken at 23 institutions in the United States. Patients were included who underwent cervical spine surgery from January 1, 2005, to December 31, 2011, and had misplacement of screws requiring reoperation. Institutional review board approval was obtained at all participating institutions, and detailed records were sent to a central data center. RESULTS: A total of 12 903 patients met the inclusion criteria and were analyzed. There were 11 instances of screw backout requiring reoperation, for an incidence of 0.085%. There were 7 posterior procedures. Importantly, there were no changes in the health-related quality-of-life metrics due to this complication. There were no new neurologic deficits; a patient most often presented with pain, and misplacement was diagnosed on plain X-ray or computed tomography scan. The most common location for screw backout was C6 (36%). CONCLUSIONS: This study represents the largest series to tabulate the incidence of misplacement of screws following cervical spine surgery, which led to revision procedures. The data suggest this is a rare event, despite the widespread use of cervical fixation. Patients suffering this complication can require revision, but do not usually suffer neurologic sequelae. These patients have increased cost of care. Meticulous technique and thorough knowledge of the relevant anatomy are the best means of preventing this complication

Permanent biventricular ICD-implantation in a heart failure second re-do-CABG patient: a case report

Biventricular pacing has been suggested in end-stage heart failure. We present a 59-year-old patient undergoing second re-do CABG (coronary artery bypass graft) and carotid artery endarterectomy. Ejection fraction was 15%, QRS-width 175 ms. Following the carotid and CABG procedure, an implanted single-chamber ICD (implantable cardioverter defibrillator) was upgraded to permanent biventricular DDD pacing by implantation of one epicardial left ventricular and one epicardial atrial electrode. At follow-up two months postoperatively ejection fraction had significantly improved to 45%, the patient underwent stress test with adequate load and reported a good quality of life