45 research outputs found
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Customized design of hearing aids using statistical shape learning
3D shape modeling is a crucial component of rapid prototyping systems
that customize shapes of implants and prosthetic devices to a patient’s
anatomy. In this paper, we present a solution to the problem of customized 3D
shape modeling using a statistical shape analysis framework. We design a novel
method to learn the relationship between two classes of shapes, which are related
by certain operations or transformation. The two associated shape classes are
represented in a lower dimensional manifold, and the reduced set of parameters
obtained in this subspace is utilized in an estimation, which is exemplified by a
multivariate regression in this paper.We demonstrate our method with a felicitous
application to estimation of customized hearing aid devices
Multilinear maps and tensor norms on operator systems
AbstractWe extend work of Christensen and Sinclair on completely bounded multilinear forms to the case of subspaces of C∗ algebras, and obtain a representation theorem and a Hahn-Banach extension theorem for such maps. In the second part of the paper the Haagerup norms on tensor products are investigated, and we obtain new characterizations of these quantities
SERUM LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE IN NORMAL CHILDREN AND PATIENTS WITH VARIOUS CLINICAL DISORDERS
Serum concentrations of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were determined in 329 normal children and 185 individuals with endocrinological abnormalities or variations of development. A significant increase of gonadotrophins is noted at the onset of puberty among the boys and at menarche for girls. The values are compared with serum concentrations of LH and FSH in children with abnormalities of sexual development, pituitary malfunction as well as other clinical abnormalities. Comparable levels for age and stage of development were found for premature thelarche, premature adrenarche, cryptorchidism, male pseudohermaphroditism and pubertal gynaecomastia. Hypogonadal individuals (Klinefelter's and Turner's syndrome, pure ovarian dysgenesis and testicular dysgenesis) have markedly elevated values while those with pituitary hypofunction had low values. Patients with sexual prococity tended to have elevated concentrations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73601/1/j.1365-2265.1973.tb00427.x.pd
Adsorption of mono- and multivalent cat- and anions on DNA molecules
Adsorption of monovalent and multivalent cat- and anions on a deoxyribose
nucleic acid (DNA) molecule from a salt solution is investigated by computer
simulation. The ions are modelled as charged hard spheres, the DNA molecule as
a point charge pattern following the double-helical phosphate strands. The
geometrical shape of the DNA molecules is modelled on different levels ranging
from a simple cylindrical shape to structured models which include the major
and minor grooves between the phosphate strands. The densities of the ions
adsorbed on the phosphate strands, in the major and in the minor grooves are
calculated. First, we find that the adsorption pattern on the DNA surface
depends strongly on its geometrical shape: counterions adsorb preferentially
along the phosphate strands for a cylindrical model shape, but in the minor
groove for a geometrically structured model. Second, we find that an addition
of monovalent salt ions results in an increase of the charge density in the
minor groove while the total charge density of ions adsorbed in the major
groove stays unchanged. The adsorbed ion densities are highly structured along
the minor groove while they are almost smeared along the major groove.
Furthermore, for a fixed amount of added salt, the major groove cationic charge
is independent on the counterion valency. For increasing salt concentration the
major groove is neutralized while the total charge adsorbed in the minor groove
is constant. DNA overcharging is detected for multivalent salt. Simulations for
a larger ion radii, which mimic the effect of the ion hydration, indicate an
increased adsorbtion of cations in the major groove.Comment: 34 pages with 14 figure
Markov Random Field Restoration of Point Correspondences for Active Shape Modelling
International audienceno abstrac