105 research outputs found

    Collaborative dynamic decision making: a case study from B2B supplier selection

    Get PDF
    The problem of supplier selection can be easily modeled as a multiple-criteria decision making (MCDM) problem: businesses express their preferences with respect to suppliers, which can then be ranked and selected. This approach has two major pitfalls: first, it does not consider a dynamic scenario, in which suppliers and their ratings are constantly changing; second, it only addressed the problem from the point of view of a single business, and cannot be easily applied when considering more than one business. To overcome these problems, we introduce a method for supplier selection that builds upon the dynamic MCDM framework of Campanella and Ribeiro [1] and, by means of a linear programming model, can be used in the case of multiple collaborating businesses plan- ning their next batch of orders together.Fundação para a Ciência e a Tecnologia, Portugal, under contract CONT DOUT/49/UNINOVA/0/5902/1/200

    PatchPerPixMatch for automated 3d search of neuronal morphologies in light microscopy

    Get PDF
    Studies of individual neurons in the Drosophila nervous system are facilitated by transgenic lines that sparsely and repeatably label respective neurons of interest. Sparsity can be enhanced by means of intersectional approaches like the split-GAL4 system, which labels the positive intersection of the expression patterns of two (denser) GAL4 lines. To this end, two GAL4 lines have to be identified as labelling a neuron of interest. Current approaches to tackling this task include visual inspection, as well as automated search in 2d projection images, of single cell multi-color flip-out (MCFO) acquisitions of GAL4 expression patterns. There is to date no automated method available that performs full 3d search in MCFO imagery of GAL4 lines, nor one that leverages automated reconstructions of the labelled neuron morphologies. To close this gap, we propose PatchPerPixMatch, a fully automated approach for finding a given neuron morphology in MCFO acquisitions of Gen1 GAL4 lines. PatchPerPixMatch performs automated instance segmentation of MCFO acquisitions, and subsequently searches for a target neuron morphology by minimizing an objective that aims at covering the target with a set of well-fitting segmentation fragments. PatchPerPixMatch is computationally efficient albeit being full 3d, while also highly robust to inaccuracies in the automated neuron instance segmentation. We are releasing PatchPerPixMatch search results for ~30,000 neuron morphologies from the Drosophila hemibrain in ~20,000 MCFO acquisitions of ~3,500 Gen1 GAL4 lines

    Nitrate stable isotopes and major ions in snow and ice samples from four Svalbard sites

    Get PDF
    Increasing reactive nitrogen (N-r) deposition in the Arctic may adversely impact N-limited ecosystems. To investigate atmospheric transport of N-r to Svalbard, Norwegian Arctic, snow and firn samples were collected from glaciers and analysed to define spatial and temporal variations (1 10 years) in major ion concentrations and the stable isotope composition (delta N-15 and delta O-18) of nitrate (NO3-) across the archipelago. The delta N-15(NO3-) and delta O-18(NO3-) averaged -4 parts per thousand and 67 parts per thousand in seasonal snow (2010-11) and -9 parts per thousand and 74 parts per thousand in firn accumulated over the decade 2001-2011. East-west zonal gradients were observed across the archipelago for some major ions (non-sea salt sulphate and magnesium) and also for delta N-15(NO3-) and delta O-18(NO3-) in snow, which suggests a different origin for air masses arriving in different sectors of Svalbard. We propose that snowfall associated with long-distance air mass transport over the Arctic Ocean inherits relatively low delta N-15(NO3-) due to in-transport N isotope fractionation. In contrast, faster air mass transport from the north-west Atlantic or northern Europe results in snowfall with higher delta N-15(NO3-) because in-transport fractionation of N is then time-limited

    Molecular biology of baculovirus and its use in biological control in Brazil

    Full text link

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

    Get PDF
    Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Influences de la sylviculture sur le risque de dégâts biotiques et abiotiques dans les peuplements forestiers

    Full text link

    Long-term changes in the hydrography of the European shelf seas since 1905, and the effects of these upon the distribution and abundance of various marine organisms

    No full text
    SIGLEAvailable from British Library Document Supply Centre- DSC:D76378 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Modelling the timing of plankton production and its effect on recruitment of cod (Gadus morhua)

    No full text
    The match–mismatch hypothesis, which relates timing of plankton production to recruitment of fish, is difficult to test for a number of reasons, not least of which is lack of adequately resolved spatial and seasonal data for matching information on fish larvae and their food. Spatial, seasonal, and interannual variability of water-column stratification, primary production, and copepod egg production can be modelled, but do such models adequately represent features of interannual variability that affect survival of fish larvae? Information on the timing and location of cod larvae in the Irish Sea and at Iceland is used to identify target areas for which long-term hindcasts of plankton production are made using a one-dimensional model of water-column stratification and production of chlorophyll and copepod eggs, driven by hourly meteorological data. Hindcast spring chlorophyll and nitrate values for Faxa Bay (Iceland) in 1966 correspond well with observations. Hindcast interannual variability in Calanus egg production appears to have a significant effect on cod recruitment in the Irish Sea and at Iceland. While the conclusions from such a limited study must be tentative, they suggest that local meteorological forcing, in areas where cod larvae occur, exerts an effect on their survival, owing to the match between plankton production and larval feeding
    corecore