On the energy leakage of discrete wavelet transform

The energy leakage is an inherent deficiency of discrete wavelet transform (DWT) which is often ignored by researchers and practitioners. In this paper, a systematic investigation into the energy leakage is reported. The DWT is briefly introduced first, and then the energy leakage phenomenon is described using a numerical example as an illustration and its effect on the DWT results is discussed. Focusing on the Daubechies wavelet functions, the band overlap between the quadrature mirror analysis filters was studied and the results reveal that there is an unavoidable tradeoff between the band overlap degree and the time resolution for the DWT. The dependency of the energy leakage to the wavelet function order was studied by using a criterion defined to evaluate the severity of the energy leakage. In addition, a method based on resampling technique was proposed to relieve the effects of the energy leakage. The effectiveness of the proposed method has been validated by numerical simulation study and experimental study

The extreme colliding-wind system Apep : resolved imagery of the central binary and dust plume in the infrared

The recent discovery of a spectacular dust plume in the system 2XMM J160050.7–514245 (referred to as ‘Apep’) suggested a physical origin in a colliding-wind binary by way of the ‘Pinwheel’ mechanism. Observational data pointed to a hierarchical triple-star system, however, several extreme and unexpected physical properties seem to defy the established physics of such objects. Most notably, a stark discrepancy was found in the observed outflow speed of the gas as measured spectroscopically in the line-of-sight direction compared to the proper motion expansion of the dust in the sky plane. This enigmatic behaviour arises at the wind base within the central Wolf–Rayet binary: a system that has so far remained spatially unresolved. Here, we present an updated proper motion study deriving the expansion speed of Apep’s dust plume over a 2-year baseline that is four times slower than the spectroscopic wind speed, confirming and strengthening the previous finding. We also present the results from high angular resolution near-infrared imaging studies of the heart of the system, revealing a close binary with properties matching a Wolf–Rayet colliding-wind system. Based on these new observational constraints, an improved geometric model is presented yielding a close match to the data, constraining the orbital parameters of the Wolf–Rayet binary and lending further support to the anisotropic wind model

Measurement of adsorption of a single component from the liquid phase : modelling investigation and sensitivity analysis

In this work, we consider an alternative approach for the measurement of adsorption from the liquid phase. Consider a mixture consisting of a non-adsorbed component (B) and an adsorbed component (A) present at some low concentration. Initially, a feed of component B only flows through a column packed with an adsorbent. Then, the feed is switched to the mixture of A and B. As soon as the mixture enters the column, there will be a reduction in the outlet flow rate as component A leaves the liquid phase and passes into the adsorbed phase. There are three stages to this work. The first is to develop overall and component balances to show how the amount adsorbed of component A can be determined from the variation in the column outlet flow rate. The second is to determine the actual variation in the column outlet flow rate for both plug flow and axial-dispersed plug flow. The final stage is to consider the suitability of a gravity-fed system to deliver the feed to the column. An analysis of the results shows that the experimental arrangement should be able to accurately monitor adsorption from the liquid phase where the mass fraction of the solute is of the order of 1%: the limiting experimental factor is how constant the volumetric flow rate of the liquid feed can be maintained

A Method for Compiling and Executing Expressive Assertions

Programming with assertions constitutes an effective tool to detect and correct programming errors. The ability of executing formal specifications is essential in order to test automatically a program with respect to its assertions. However, formal specifications may describe recursive models which are difficult to identify so current assertion checkers limit, in a considerable way, the expressivity of the assertion language. In this paper, we are interested in showing how transformational synthesis can help to execute “expressive” assertions of the form ∀x(r(x) ⇔ QyR(x, y)) where x is a set of variables to be instantiated at execution time, Q is an existential or universal quantifier and R a quantifier free formula in the language of a particular first-order theory A we call assertion context. The class of assertion contexts is interesting because it presents a balance between expressiveness for writing assertions and existence of effective methods for executing them by means of synthesized (definite) logic programs

Spin relaxation in (110) and (001) InAs/GaSb superlattices

We report an enhancement of the electron spin relaxation time (T1) in a (110) InAs/GaSb superlattice by more than an order of magnitude (25 times) relative to the corresponding (001) structure. The spin dynamics were measured using polarization sensitive pump probe techniques and a mid-infrared, subpicosecond PPLN OPO. Longer T1 times in (110) superlattices are attributed to the suppression of the native interface asymmetry and bulk inversion asymmetry contributions to the precessional D'yakonov Perel spin relaxation process. Calculations using a nonperturbative 14-band nanostructure model give good agreement with experiment and indicate that possible structural inversion asymmetry contributions to T1 associated with compositional mixing at the superlattice interfaces may limit the observed spin lifetime in (110) superlattices. Our findings have implications for potential spintronics applications using InAs/GaSb heterostructures.Comment: 4 pages, 2 figure

The behavior of cold-formed steel and Belian hardwood self-tapping screw connections

Cold-formed steel has been widely used to retrofit and restore buildings, especially timber buildings. This is because the material is readily available, flexible, and lightweight. However, limited research is available with little assessment concerning cold-formed steel and hardwood connection performance. This paper experimentally studies the behavior of connections composed of self-tapping screws, cold-formed steel, and Belian hardwood. Five connection configurations were investigated, where the ultimate load-carrying capacity of the connection was determined through a sequence of shear and tension tests. The results showed that the connection failed by screw withdrawal under tension load. However, when loaded in shear, the failure mode of the connection changed from screw failure when the screw head was at the Belian side to screw rotation when the screw head was at the cold-formed steel side. The performance of current design guidance in Eurocode 5 was assessed by comparing the strengths obtained from the experiments. The comparison results showed that Eurocode 5 is conservative in predicting the performance of self-tapping screw connection composed of cold-formed steel and Belian hardwood in tension. However, it was overly conservative in predicting the shear strength of the connection as the design strengths are overestimated by around 60%

ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations

Defective FUS metabolism is strongly associated with amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD), but the mechanisms linking FUS to disease are not properly understood. However, many of the functions disrupted in ALS/FTD are regulated by signalling between the endoplasmic reticulum (ER) and mitochondria. This signalling is facilitated by close physical associations between the two organelles that are mediated by binding of the integral ER protein VAPB to the outer mitochondrial membrane protein PTPIP51, which act as molecular scaffolds to tether the two organelles. Here, we show that FUS disrupts the VAPB–PTPIP51 interaction and ER–mitochondria associations. These disruptions are accompanied by perturbation of Ca2+ uptake by mitochondria following its release from ER stores, which is a physiological read‐out of ER–mitochondria contacts. We also demonstrate that mitochondrial ATP production is impaired in FUS‐expressing cells; mitochondrial ATP production is linked to Ca2+ levels. Finally, we demonstrate that the FUS‐induced reductions to ER–mitochondria associations and are linked to activation of glycogen synthase kinase‐3β (GSK‐3β), a kinase already strongly associated with ALS/FTD

Intrusive memories of trauma: A target for research bridging cognitive science and its clinical application.

Intrusive memories of a traumatic event can be distressing and disruptive, and comprise a core clinical feature of post-traumatic stress disorder (PTSD). Intrusive memories involve mental imagery-based impressions that intrude into mind involuntarily, and are emotional. Here we consider how recent advances in cognitive science have fueled our understanding of the development and possible treatment of intrusive memories of trauma. We conducted a systematic literature search in PubMed, selecting articles published from 2008 to 2018 that used the terms "trauma" AND ("intrusive memories" OR "involuntary memories") in their abstract or title. First, we discuss studies that investigated internal (neural, hormonal, psychophysiological, and cognitive) processes that contribute to intrusive memory development. Second, we discuss studies that targeted these processes using behavioural/pharmacological interventions to reduce intrusive memories. Third, we consider possible clinical implications of this work and highlight some emerging research avenues for treatment and prevention, supplemented by new data to examine some unanswered questions. In conclusion, we raise the possibility that intrusive memories comprise an alternative, possibly more focused, target in translational research endeavours, rather than only targeting overall symptoms of disorders such as PTSD. If so, relatively simple approaches could help to address the need for easy-to-deliver, widely-scalable trauma interventions