565 research outputs found

    Some properties of evolution algebras

    Get PDF
    The paper is devoted to the study of finite dimensional complex evolu- tion algebras. The class of evolution algebras isomorphic to evolution algebras with Jordan form matrices is described. For finite dimensional complex evolution algebras the criteria of nilpotency is established in terms of the properties of corresponding matrices. Moreover, it is proved that for nilpotent n−dimensional complex evolution algebras the possible maximal nilpotency index is 1 + 2n−1 . The criteria of planarity for finite graphs is formulated by means of evolution algebras defined by graphs.Junta de Andalucía FQM-14

    Ictiólogos de la Argentina: Norberto Oscar Oldani

    Get PDF
    This series will include all those people who, by means of their contributions, great and small, played a part in the consolidation of ichthyology in Argentina. The general plan of this work consists of individual factsheets containing a list of works by each author, along with reference bibliography and, whenever possible, personal pictures and additional material. The datasheets will be published primarily in chronological order, although this is subject to change by the availability of materials for successive editions. This work represents another approach for the recovery and revalorization of those who set the foundations of Argentine ichthyology while in diverse historical circumstances. I expect this to be the beginning of a major work that achieves the description of such a significant part of the history of natural sciences in Argentina

    Short-term memory, attention, and temporal orientation as predictors of the cognitive impairment in older adults: A cross-sectional observational study

    Get PDF
    Late-life cognitive decline ranges from the mildest cases of normal, age-related change to mild cognitive impairment to severe cases of dementia. Dementia is the largest global burden for the 21st century welfare and healthcare systems. The aim of this study was to analyze the neuropsychological constructs (temporal orientation (TO), spatial orientation (SO), fixation memory (FM), attention (A), calculation (C), short-term memory (STM), language (L), and praxis (P)), semantic fluency, level of functionality, and mood that reveal the greatest deficit in the different stages ranging from normal cognition (NC) to cognitive impairment in older adults in a primary healthcare setting. The study included 337 participants (102 men, 235 women), having a mean age of 74 ± 6 years. According to their scores on the Spanish version of the Mini-Mental State Examination (MEC-35), subjects were divided into 4 groups: no deterioration (ND) (score 32-35), subtle cognitive impairment (SCI) (score 28- 31), level deterioration (LD) (score 24-27) and moderate deterioration (MD) (score 20-23). The ND group revealed significant differences in TO, STM, C, A, L, P, and S-T as compared to the other groups. The MD group (in all the neuropsychological constructs) and the ND and SCI groups showed significant differences on the Yesavage geriatric depression scale (GDS-15). All except the FM neuropsychological construct were part of the MEC-35 prediction model and all of the regression coefficients were significant for these variables in the model. Furthermore, the highest average percentage of relative deterioration occurs between LD and MD and the greatest deterioration is observed in the STM for all groups, including A and TO for the LD and MD groups. Based on our findings, community programs have been implemented that use cognitive stimulation to prevent cognitive decline and to maintain the neuropsychological constructs. © 2021 Gómez-Soria et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

    Solving non-uniqueness in agglomerative hierarchical clustering using multidendrograms

    Full text link
    In agglomerative hierarchical clustering, pair-group methods suffer from a problem of non-uniqueness when two or more distances between different clusters coincide during the amalgamation process. The traditional approach for solving this drawback has been to take any arbitrary criterion in order to break ties between distances, which results in different hierarchical classifications depending on the criterion followed. In this article we propose a variable-group algorithm that consists in grouping more than two clusters at the same time when ties occur. We give a tree representation for the results of the algorithm, which we call a multidendrogram, as well as a generalization of the Lance and Williams' formula which enables the implementation of the algorithm in a recursive way.Comment: Free Software for Agglomerative Hierarchical Clustering using Multidendrograms available at http://deim.urv.cat/~sgomez/multidendrograms.ph

    Oxfordian microbial laminites from La Manga Formation, Neuquén Basin, Argentina: Remarkable nanobacteria preservation

    Get PDF
    Exceptionally preserved stromatolites have been found in the shallow marine carbonate facies of the Callovian-Oxfordian La Manga Formation, in the Neuquén Basin (Argentina). The stromatolites exhibit planar and crinkle lamination, often disrupted by sheet-cracks, mudcracks, and fenestral structures, which indicate periodic subaerial exposure. These and other evidences suggest that these stromatolites grew in low energy upper intertidal to lower supratidal environments. They consist of fine micrite/microsparite crystal fabrics (with a remarkable lack of allochems) that define submillimiter alternations of dense laminae. Extensive SEM examinations of polished samples of the stromatolites reveal exceptional preservation of rod-shaped bacteria, coccoid like microorganisms, and abundant aggregates of framboidal pyrite. The rod-like bacteria consists of a network of irregular distributed filaments, which range from 150 nm to an uncommon 640 nm in length; diameters range from 54 nm to 90 nm. Subspherical bodies range in size between 70 and 89 nm. The presence of abundant framboidal pyrites is interpreted as the result of the metabolic activity of sulfate–reducing bacteria and decay of organic matter.Se describen estromatolitos excepcionalmente preservados en facies carbonáticas marinas someras en la Formación La Manga, de edad Calloviense-Oxfordiense, en la Cuenca de Neuquén (Argentina). Los estromatolitos muestran una laminación tanto planar como ondulada, frecuentemente alterada por estructuras de tipo fenestral, y sheet y mud-crack, que indican etapas de exposición subaérea. Estas y otras características sugieren que estos estromatolitos crecieron en ambientes de baja energía, intermareales altos y supramareales. Están constituidos por una fábrica de micrita-microesparita (con una destacada ausencia de aloquímicos) que constituyen alternancias submilimétricas de laminación densa. Estudios detallados con SEM sobre muestras pulidas revelan una preservación excepcional con morfología alargada, microorganismos tipo cocoide, y abundantes agregados de pirita framboidal. Las bacterias con morfologías alargadas están constituyendo una red irregularmente distribuida de filamentos que oscilan en tamaño desde 150 nm hasta, excepcionalmente, 640 nm en longitud; el diámetro oscila entre 50 nm y 90 nm. Las morfologías subesféricas oscilan entre 70 nm y 89 nm. La presencia de abundantes piritas framboidales es interpretada como resultado de una actividad metabólica de bacterias sulfato-reductoras y la descomposición de materia orgánica

    Systematic Review on the Efficacy of Fexofenadine in Seasonal Allergic Rhinitis: A Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Clinical Trials

    Get PDF
    Rationale: Evidence-based medicine represents the effort to highlight the best intervention for patients, clinicians, and policy makers, each from their respective viewpoint, to solve a particular health condition. According to a recently diffused grading system of evidence and recommendations for medical interventions, efficacy and safety represent 2 of the most important features to consider, and data from meta-analyses of randomized controlled clinical trials (RCTs) is the strongest supporting demonstration. Fexofenadine has been used for its efficacy and safety in the treatment of allergic rhinitis (AR) for many years although no meta-analyses supporting its use currently exist. The aim of this study is to assess for the first time the efficacy and safety of fexofenadine in the treatment of AR by means of a meta-analytic analysis of existing RCTs. Since specific evidence should be provided to address recommendations in a pediatric population, the quality of the estimates of this subgroup analysis is assessed. Methods: All double-blind, placebo-controlled randomized trials assessing the efficacy of fexofenadine in AR were searched for in OVID, Medline, and Embase databases up to December 2007. Outcomes were extracted from original articles; when this information was not available, the authors of each trial were contacted. Some graphics were digitalized. The RevMan 5 program was used to perform the analysis. GradePro 3.2.2 was used to assess the quality of the evidence for a pediatric population. Results: Of 2,152 identified articles, 20 were potentially relevant trials. Eight studies satisfied the inclusion criteria and were included in the meta-analysis. The main reasons for exclusion were: unnatural exposure, strong study limitations, an atypical outcome measurement, a design for other outcomes, and not being a placebo-controlled, single-blind study. Seven trials investigated a mixed population of adults and children, 1 trial investigated only children, and 1 trial only adults. In 1,833 patients receiving fexofenadine (1,699 placebo), a significant reduction of the daily reflective total symptom scores (TSS) (SMD –0.42; 95% CI –0.49 to –0.35, p < 0.00001) was found. Positive results were also found for morning instantaneous TSS and individual nasal symptom scores (sneezing, rhinorrhea, itching, and congestion). The safety analysis did not show a significant difference in reported adverse events (AE) between the active and placebo treatment groups (OR = 1.03; 95% CI 0.87–1.22, p = 0.75). A very low heterogeneity between the studies was detected, so a fixed-effects model was used. The mean quality level of the included trials was medium. Specific information for a pediatric population may be assumed with a moderate quality of evidence from only 1 study and with a low quality of evidence, mainly due to indirectness, from the others. Conclusions: This study has 5 major strengths: it represents the first attempt to evaluate the efficacy and safety of fexofenadine in the treatment of AR by means of a meta-analysis of RCTs; there was consistency between positive results in terms of efficacy in TSS and in individual symptoms; a large population was studied; there was an irrelevant interstudy heterogeneity, and the AE frequency was similar in both groups. All of these values encourage the recommendation of fexofenadine for AR. Further research focused on the benefits and disadvantages for a pediatric population is needed

    14. VIGENCIA DE LOS CONCEPTOS, MÉTODOS, HERRAMIENTAS Y MATRICES DE LA PLANEACIÓN ESTRATÉGICA: UNA REVISIÓN BIBLIOGRÁFICA

    Get PDF
    Las Micro, Pequeñas y Medianas empresas (Mipymes) constituyen gran parte del tejido empresarial a nivel local, esto les asiente una alta influencia en la economía del país debido a la generación de empleo y de riqueza. Cabe destacar que el éxito y la permanencia de estas, obedece entre muchos factores a la planeación estratégica de las mismas. Sin embargo, el desconocimiento de métodos de planeación y la priorización de acciones diarias de la actividad del negocio hace que las empresas no planeen sus acciones y en consecuencia fracasen en el primer y segundo año de su creación. Es por ello, que esta investigación está encaminada a plantear unas bases para el desarrollo de una herramienta tecnológica que le permita a las Mipymes la planificación de sus operaciones estratégicas y tácticas a corto, mediano y largo plazo. El estudio consta de tres fases: estado del arte, desarrollo del aplicativo, y transferencia tecnológica. Para esta primera fase, se realizó una revisión bibliográfica de los últimos 5 años con el fin de identificar conceptos, métodos, herramientas y matrices implementadas por diversas compañías, de los cuales algunos de ellos están plasmados en el presente artículo de revisión bibliográfica. De esta manera se pretende tener el insumo necesario para la propuesta del desarrollo de la herramienta tecnológica objeto de la investigación y con ello lograr contribuir en la actividad misional de las Mipymes
    corecore