Interrogation of fibre Bragg grating sensors using an arrayed waveguide grating

We experimentally investigate the use of an arrayed waveguide grating (AWG) to interrogate fibre Bragg grating (FBG) sensors. A broadband light source is used to illuminate the FBG sensors. Reflected spectral information is directed to the AWG containing integral photodetectors providing 40 electrical outputs. Three methods are described to interrogate FBG sensors. The first technique makes use of the wavelength-dependent transmission profile of an AWG channel passband, giving a usable range of 500 με and a dynamic strain resolution of 96 nε Hz-1/2 at 13 Hz. The second approach utilizes wide gratings larger than the channel spacing of the AWG; by monitoring the intensity present in several neighbouring AWG channels an improved range of 1890 με was achieved. The third method improves the dynamic range by utilizing a heterodyne approach based on interferometric wavelength shift detection, providing an improved dynamic strain resolution of 17 nε Hz -1/2 at 30 Hz. © 2005 IOP Publishing Ltd

Interrogation of fibre Bragg grating sensors using an arrayed waveguide grating

We experimentally investigate the use of an arrayed waveguide grating (AWG) to interrogate fibre Bragg grating (FBG) sensors. A broadband light source is used to illuminate the FBG sensors. Reflected spectral information is directed to the AWG containing integral photodetectors providing 40 electrical outputs. Three methods are described to interrogate FBG sensors. The first technique makes use of the wavelength-dependent transmission profile of an AWG channel passband, giving a usable range of 500 με and a dynamic strain resolution of 96 nε Hz-1/2 at 13 Hz. The second approach utilizes wide gratings larger than the channel spacing of the AWG; by monitoring the intensity present in several neighbouring AWG channels an improved range of 1890 με was achieved. The third method improves the dynamic range by utilizing a heterodyne approach based on interferometric wavelength shift detection, providing an improved dynamic strain resolution of 17 nε Hz -1/2 at 30 Hz. © 2005 IOP Publishing Ltd

Quasars and their host galaxies

This review attempts to describe developments in the fields of quasar and quasar host galaxies in the past five. In this time period, the Sloan and 2dF quasar surveys have added several tens of thousands of quasars, with Sloan quasars being found to z>6. Obscured, or partially obscured quasars have begun to be found in significant numbers. Black hole mass estimates for quasars, and our confidence in them, have improved significantly, allowing a start on relating quasar properties such as radio jet power to fundamental parameters of the quasar such as black hole mass and accretion rate. Quasar host galaxy studies have allowed us to find and characterize the host galaxies of quasars to z>2. Despite these developments, many questions remain unresolved, in particular the origin of the close relationship between black hole mass and galaxy bulge mass/velocity dispersion seen in local galaxies.Comment: Review article, to appear in Astrophysics Update

The Fueling and Evolution of AGN: Internal and External Triggers

In this chapter, I review the fueling and evolution of active galactic nuclei (AGN) under the influence of internal and external triggers, namely intrinsic properties of host galaxies (morphological or Hubble type, color, presence of bars and other non-axisymmetric features, etc) and external factors such as environment and interactions. The most daunting challenge in fueling AGN is arguably the angular momentum problem as even matter located at a radius of a few hundred pc must lose more than 99.99 % of its specific angular momentum before it is fit for consumption by a BH. I review mass accretion rates, angular momentum requirements, the effectiveness of different fueling mechanisms, and the growth and mass density of black BHs at different epochs. I discuss connections between the nuclear and larger-scale properties of AGN, both locally and at intermediate redshifts, outlining some recent results from the GEMS and GOODS HST surveys.Comment: Invited Review Chapter to appear in LNP Volume on "AGN Physics on All Scales", Chapter 6, in press. 40 pages, 12 figures. Typo in Eq 5 correcte

Fecal microbiota transplantation influences procarcinogenic Escherichia coli in recipient recurrent Clostridioides difficile patients

BACKGROUND & AIMS: Patients with multiple recurrent Clostridioides difficile infection (rCDI) have a disturbed gut microbiota that can be restored by fecal microbiota trans-plantation (FMT). Despite extensive screening, healthy feces donors may carry bacteria in their intestinal tract that could have long-term health effects, such as potentially procarci-nogenic polyketide synthase-positive (pks+) Escherichia coli. Here, we aim to determine whether the pks abundance and persistence of pks+ E coli is influenced by pks status of the donor feces. METHODS: In a cohort of 49 patients with rCDI treated with FMT and matching donor samples-the largest cohort of its kind, to our knowledge-we retrospectively screened fecal metagenomes for pks+ E coli and compared the presence of pks in patients before and after treatment and to their respective donors. RESULTS: The pks island was more prevalent (P = .026) and abundant (P < .001) in patients with rCDI (pre-FMT, 27 of 49 [55%]; median, 0.46 reads per kilobase per million [RPKM] pks) than in healthy donors (3 of 8 donors [37.5%], 11 of 38 samples [29%]; median, 0.01 RPKM pks). The pks status of patients post-FMT depended on the pks status of the donor suspension with which the patient was treated (P = .046). Particularly, persistence (8 of 9 cases) or clearance (13 of 18) of pks+ E coli in pks+ patients was correlated to pks in the donor (P = .004). CONCLUSIONS: We conclude that FMT contrib-utes to pks+ E coli persistence or eradication in patients with rCDI but that donor-to-patient transmission of pks+ E coli is unlikely.Cellular mechanisms in basic and clinical gastroenterology and hepatolog

Magnetic Fields, Relativistic Particles, and Shock Waves in Cluster Outskirts

It is only now, with low-frequency radio telescopes, long exposures with high-resolution X-ray satellites and gamma-ray telescopes, that we are beginning to learn about the physics in the periphery of galaxy clusters. In the coming years, Sunyaev-Zeldovich telescopes are going to deliver further great insights into the plasma physics of these special regions in the Universe. The last years have already shown tremendous progress with detections of shocks, estimates of magnetic field strengths and constraints on the particle acceleration efficiency. X-ray observations have revealed shock fronts in cluster outskirts which have allowed inferences about the microphysical structure of shocks fronts in such extreme environments. The best indications for magnetic fields and relativistic particles in cluster outskirts come from observations of so-called radio relics, which are megaparsec-sized regions of radio emission from the edges of galaxy clusters. As these are difficult to detect due to their low surface brightness, only few of these objects are known. But they have provided unprecedented evidence for the acceleration of relativistic particles at shock fronts and the existence of muG strength fields as far out as the virial radius of clusters. In this review we summarise the observational and theoretical state of our knowledge of magnetic fields, relativistic particles and shocks in cluster outskirts.Comment: 34 pages, to be published in Space Science Review

Effect of Oral Alendronate on Bone Mineral Density and the Incidence of Fractures in Postmenopausal Osteoporosis

BACKGROUND Postmenopausal osteoporosis is a serious health problem, and additional treatments are needed. METHODS We studied the effects of oral alendronate, an aminobisphosphonate, on bone mineral density and the incidence of fractures and height loss in 994 women with postmenopausal osteoporosis. The women were treated with placebo or alendronate (5 or 10 mg daily for three years, or 20 mg for two years followed by 5 mg for one year); all the women received 500 mg of calcium daily. Bone mineral density was measured by dual-energy x-ray absorptiometry. The occurrence of new vertebral fractures and the progression of vertebral deformities were determined by an analysis of digitized radiographs, and loss of height was determined by sequential height measurements. RESULTS The women receiving alendronate had significant, progressive increases in bone mineral density at all skeletal sites, whereas those receiving placebo had decreases in bone mineral density. At three years, the mean (±SE) differences in bone mineral density between the women receiving 10 mg of alendronate daily and those receiving placebo were 8.8±0.4 percent in the spine, 5.9±0.5 percent in the femoral neck, 7.8±0.6 percent in the trochanter, and 2.5±0.3 percent in the total body (P CONCLUSIONS Daily treatment with alendronate progressively increases the bone mass in the spine, hip, and total body and reduces the incidence of vertebral fractures, the progression of vertebral deformities, and height loss in postmenopausal women with osteoporosis

Evidence of Color Coherence Effects in W+jets Events from ppbar Collisions at sqrt(s) = 1.8 TeV

We report the results of a study of color coherence effects in ppbar collisions based on data collected by the D0 detector during the 1994-1995 run of the Fermilab Tevatron Collider, at a center of mass energy sqrt(s) = 1.8 TeV. Initial-to-final state color interference effects are studied by examining particle distribution patterns in events with a W boson and at least one jet. The data are compared to Monte Carlo simulations with different color coherence implementations and to an analytic modified-leading-logarithm perturbative calculation based on the local parton-hadron duality hypothesis.Comment: 13 pages, 6 figures. Submitted to Physics Letters

Formation of stars and planets: the role of magnetic fields

Star formation is thought to be triggered by gravitational collapse of the dense cores of molecular clouds. Angular momentum conservation during the collapse results in the progressive increase of the centrifugal force, which eventually halts the inflow of material and leads to the development of a central mass surrounded by a disc. In the presence of an angular momentum transport mechanism, mass accretion onto the central object proceeds through this disc, and it is believed that this is how stars typically gain most of their mass. However, the mechanisms responsible for this transport of angular momentum are not well understood. Although the gravitational field of a companion star or even gravitational instabilities (particularly in massive discs) may play a role, the most general mechanisms are turbulence viscosity driven by the magnetorotational instability (MRI), and outflows accelerated centrifugally from the surfaces of the disc. Both processes are powered by the action of magnetic fields and are, in turn, likely to strongly affect the structure, dynamics, evolutionary path and planet-forming capabilities of their host discs. The weak ionisation of protostellar discs, however, may prevent the magnetic field from effectively coupling to the gas and shear and driving these processes. Here I examine the viability and properties of these magnetically-driven processes in protostellar discs. The results indicate that, despite the weak ionisation, the magnetic field is able to couple to the gas and shear for fluid conditions thought to be satisfied over a wide range of radii in these discs.Comment: Invited Review. 11 figures and 1 table. Accepted for publication in Astrophysics & Space Scienc