Influence of preparation procedures on the phenolic content, antioxidant and antidiabetic activities of green and black teas

The influence of common tea preparation procedures (temperature, infusion time, consumption time interval and tea bag/loose-leaf) and the type of water used, on the total phenolic content (TPC), the radical scavenging activity and the alpha-glucosidase inhibitory activity were assessed. Higher TPC and antioxidant activity were obtained when using lower mineralized waters. Tea bags also evidenced higher antioxidant activity than loose-leaf samples. Under the same conditions (90 degrees C and five minutes of infusion time) green tea contains almost twice the quantity of polyphenols and the free radical scavenging ability of black tea. In the alpha-glucosidase assay all infusions were active (97-100 %). Furthermore, HPLC allowed to identify some of the polyphenols present in both teas and to monitor their composition change with time. After twenty-four hours, the antioxidant activity was maintained without significant changes, but a small decrease in enzyme inhibition was observed, although this activity was still very high.info:eu-repo/semantics/publishedVersio

Multi-lingual agents through multi-headed neural networks

This paper considers cooperative Multi-Agent Reinforcement Learning, focusing on emergent communication in settings where multiple pairs of independent learners interact at varying frequencies. In this context, multiple distinct and incompatible languages can emerge. When an agent encounters a speaker of an alternative language, there is a requirement for a period of adaptation before they can efficiently converse. This adaptation results in the emergence of a new language and the forgetting of the previous language. In principle, this is an example of the Catastrophic Forgetting problem which can be mitigated by enabling the agents to learn and maintain multiple languages. We take inspiration from the Continual Learning literature and equip our agents with multi-headed neural networks which enable our agents to be multi-lingual. Our method is empirically validated within a referential MNIST based communication game and is shown to be able to maintain multiple languages where existing approaches cannot.Comment: Cooperative AI workshop NeurIPS 202

Caracterización de la variabilidad intra-racial en los parámetros productivos de añojos cebados en el sur de España

publishedTomo I . Sección: Sistemas Ganaderos-Economía y Gestión. Sesión: Vacuno carne II. Ponencia nº

Precise OBS location at the sea bottom in active seismic profiles using the air gun shot records

The Norcaribe campaign, in November – December 2013, funded by Spanish Ministry of Innovation and Science (Norcaribe Project CGL2010-17715), was performed on board of the Spanish research vessel “Sarmiento de Gamboa” around the Hispaniola island, also with the participation of the Dominic Republic Navy patrol vessels and several Haiti and Dominic Republic institutions. During the campaign, a 200 km long, wide-amgle refraction seismic profile was carried out crossing the Beata ridge. The air gun signal (5100 ci) was recorded by 15 OBSs deployed along the seismic line in water depths between 2.300 meters and 4.320 meters. To obtain the section records, the OBS position is needed, usually the deployment location is used, but the OBS can drift while is sinking due to the deep oceanic currents. The recovery locations at surface could provide information about the drift, assuming a constant sea current since the deployment to the recovery, but it is imprecise. In this work we show a method to obtain a precise location of the OBS at the sea bottom using a high-resolution bathymetry and the OBS record of the closest air gun shots of the profile. Also, the preliminary results for the Norcaribe campaign (Beata ridge profile) are shown.Peer Reviewe

Heart Rate Variability and Exceptional Longevity

Centenarians are the paradigm of human extreme longevity and healthy aging, because they have postponed, if not avoided, mayor age-related diseases. The purpose of this study was to investigate potential differences in resting heart rate variability (HRV) between young adults, octogenarians, and centenarians and assess whether HRV variables are predictors of all-cause mortality in centenarians. To this end, three groups of participants: young adults (N = 20; 20.6 ± 2.3 years), octogenarians (N = 18; 84.1 ± 2.6 years), and centenarians (N = 17; 101.9 ± 1.9 years) were monitored for 15 min at rest (seated, without moving or talking) to measure RR intervals, from which HRV was evaluated. Our results showed a clear decrease with age in the main parasympathetic HRV variables, as well as in the standard deviation (SD) of the RR series [SD of normal-to-normal interval (SDNN)] and in low frequency (LF) heart rate (HR) oscillations, although differences between octogenarians and centenarians did not reach statistical significance. In 14 centenarians followed until death, only SDNN showed significant correlation (¿ = 0.536; p = 0.048) with survival prognosis. Additionally, SDNN <19 ms was associated with early mortality (=1 year) in centenarians (Hazard Ratio = 5.72). In conclusion, HRV indices reflecting parasympathetic outflow as well as SDNN and LF all present an age-related reduction, which could be representative of a natural exhaustion of allostatic systems related to age. Moreover, low SDNN values (<19 ms) could be associated with early mortality in centenarians. HRV seems to play a role in exceptional longevity, which could be accounted for by centenarians’ exposome

Clustering Main Concepts from e-Mails

E–mail is one of the most common ways to communicate, assuming, in some cases, up to 75% of a company’s communication, in which every employee spends about 90 minutes a day in e–mail tasks such as filing and deleting. This paper deals with the generation of clusters of relevant words from E–mail texts. Our approach consists of the application of text mining techniques and, later, data mining techniques, to obtain related concepts extracted from sent and received messages. We have developed a new clustering algorithm based on neighborhood, which takes into account similarity values among words obtained in the text mining phase. The potential of these applications is enormous and only a few companies, mainly large organizations, have invested in this project so far, taking advantage of employees’s knowledge in future decisions

Magnetism in nanometer-thick magnetite

The oldest known magnetic material, magnetite, is of current interest for use in spintronics as a thin film. An open question is how thin can magnetite films be and still retain the robust ferrimagnetism required for many applications. We have grown one-nanometer-thick magnetite crystals and characterized them in situ by electron and photoelectron microscopies including selected-area x-ray circular dichroism. Well-defined magnetic patterns are observed in individual nano-crystals up to at least 520 K, establishing the retention of ferrimagnetism in magnetite two-unit-cells thick.Comment: 5 pages, 4 figure

Development of barley and yeast β-glucan aerogels for drug delivery by supercritical fluids

Polysaccharide aerogels are a good alternative as carriers for drug delivery, since they allow high loading of the active compounds in matrices that are non-toxic, biocompatible and from a renewable feedstock. In this work, barley and yeast β-glucans aerogels were produced by gelation in aqueous solution, followed by solvent exchange and drying with supercritical CO2. First, viscoelastic properties and melting profile of the hydrogels were determined. Then, the obtained aerogels were analyzed regarding morphology, mechanical properties and behavior in physiological fluid. Both in the hydrogels and in the aerogels, big differences were observed between barley and yeast β-glucans due to their different chain structure and gelation behavior. Finally, impregnation of acetylsalicylic acid was performed at the same time as the drying of the alcogels with supercritical CO2. The release profile of the drug in PBS was analyzed in order to determine the mechanism governing the release from the β-glucan matrix.Authors acknowledge Ministerio de Economía y Competitividad (MINECO) through project CTQ2013-44143-R and project PIP 063/ 147181 from Fundación General of the University of Valladolid for fi- nancial support. M. Salgado thanks to Ministerio de Educación, Ciencia y Deporte (MECD) for her FPU and mobility grants. S. Rodríguez-Rojo acknowledges to MINECO and UVa for her Juan de la Cierva fellowship (JCI-2012-14992). The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement number REGPOT-CT2012- 316331-POLARIS and from the project “Novel smart and biomimetic materials for innovative regenerative medicine approaches” RL1 − ABMR − NORTE-01-0124-FEDER-000016) co-financed by North Portugal Regional Operational Programme (ON.2–O Novo Norte), under the National Strategic Reference Framework (NSRF), through the European Regional Development Fund (ERDF).info:eu-repo/semantics/publishedVersio