280 research outputs found
Heat transfer characteristics of hydrid microjet-microchannel cooling module
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.The paper presents the experimental investigation of heat transfer intensification in a microjetmicrochannel
cooling module. Applied technology takes benefits from two very attractive heat removal
techniques. When jets are impinging on the surface, they have a very high kinetic energy at the stagnation
point, also in microchannels boundary layer is very thin allowing to obtain very high heat fluxes.
Main objective of this paper was to experimentally investigate the performance of a microjet-microchannel
cooling module. Intense heat transfer in the test section has been examined and described with precise
measurements of thermal and flow conditions. Reported tests were conducted under steady state conditions
for single phase liquid cooling.
Obtained database of experimental data were compared to standard cooling techniques, and compared with
superposed semi-empirical models for minichannels and microjet cooling, Mikielewicz and Muszynski
(2009). Gathered data with analytical solutions and numerical computer simulation allows the rational design
and calculation of hybrid modules and optimum performance of these modules for various industrial
applications
Fordism at Work in Canadian Coffee Shops
Although many areas of work today are characterized by post-Fordist principles, there are still significant numbers of workplaces that have adapted and continue to operate using a Fordist model, and in particular, low-paying service industries that rely on a largely female an d part-time labour force. This paper explores how the Fordist model has been adapted and extended within the Canadian coffee shop franchise industry. Qualitative interviews were conducted with staff and managers in selected coffee shops to gain a better understanding of how work is organized and managed in this industry
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity
Transfusion of red cell concentrates (RCCs) is associated with increased risk of adverse outcomes that may be affected by different blood manufacturing methods and the presence of extracellular vesicles (EVs). We investigated the effect of different manufacturing methods on hemolysis, residual cells, cell-derived EVs, and immunomodulatory effects on monocyte activity. Thirty-two RCC units produced using whole blood filtration (WBF), red cell filtration (RCF), apheresis-derived (AD), and whole blood-derived (WBD) methods were examined (n = 8 per method). Residual platelet and white blood cells (WBCs) and the concentration, cell of origin, and characterization of EVs in RCC supernatants were assessed in fresh and stored supernatants. Immunomodulatory activity of RCC supernatants was assessed by quantifying monocyte cytokine production capacity in an in vitro transfusion model. RCF units yielded the lowest number of platelet and WBC-derived EVs, whereas the highest number of platelet EVs was in AD (day 5) and in WBD (day 42). The number of small EVs (<200 nm) was greater than large EVs (≥200 nm) in all tested supernatants, and the highest level of small EVs were in AD units. Immunomodulatory activity was mixed, with evidence of both inflammatory and immunosuppressive effects. Monocytes produced more inflammatory interleukin-8 after exposure to fresh WBF or expired WBD supernatants. Exposure to supernatants from AD and WBD RCC suppressed monocyte lipopolysaccharide-induced cytokine production. Manufacturing methods significantly affect RCC unit EV characteristics and are associated with an immunomodulatory effect of RCC supernatants, which may affect the quality and safety of RCCs
Multimodal Affect and Aesthetic Experience
The term “aesthetic experience” corresponds to the inner state of
a person exposed to form and content of artistic objects.
Exploring certain aesthetic values of artistic objects, as well as
interpreting the aesthetic experience of people when exposed to
art can contribute towards understanding (a) art and (b) people’s
affective reactions to artwork. Focusing on different types of
artistic content, such as movies, music, urban art and other
artwork, the goal of this workshop is to enhance the
interdisciplinary collaboration between affective computing and
aesthetics researchers
Using Tactile Pressure Sensors to Measure Lateral Spreading Induced Earth Pressures Against a Large, Rigid Foundation
Two centrifuge tests were performed at the NEES facility at Rensselaer Polytechnic Institute (RPI) to observe lateral earth pressures mobilized against a rigid foundation element during liquefaction-induced lateral spreading, as part of a larger NEESR study aimed at developing novel approaches to mitigate the effects of seismically-induced ground failures on large, rigid foundation elements. Models were constructed in a laminar box to allow unimpeded downslope soil displacement, and the sand in the model was liquefied during the centrifuge test. Lateral pressures prior to, during, and after shaking and liquefaction were directly measured using a novel device: tactile pressure sensors. Prior to testing the production models, several 1g and centrifuge experiments were conducted to determine whether the tactile pressure sensors would accurately measure pressures. Using the tactile pressure sensor and configuration described in this paper, geostatic pressures measured prior to the shaking agreed well with the anticipated theoretical at-rest earth pressures. In this paper, we describe these initial tests, the challenges that were encountered, methods employed to overcome these challenges, and the production centrifuge tests
Ground Autonomy for an Aging Spacecraft
As it approaches the sixteenth of a 5 year prime mission, NASA's Solar Radiation and Climate Experiment (SORCE) mission continues to meet and exceed all science requirements while operating with severely degraded batteries. By 2013, the batteries had degraded such that the On Board Computer (OBC) could not be powered through eclipse. This prevents science data collection in eclipse and erases over 99% of all stored science and engineering telemetry. To mitigate these problems, the Flight Operations Team (FOT) at the Laboratory for Atmospheric and Space Physics (LASP) adopted a new operations scheme. "Daylight Only Operations" (DO-OP) transitions the spacecraft from safemode to science mode every orbit. This involved heavily automating the transition process using ground autonomy to improve spacecraft recovery time to 6 minutes - down from 3 orbits of manual commanding. While highly successful, this method of operations poses daily challenges that must be overcome using increasingly complex ground software
Identification and characterization of the maize arogenate dehydrogenase gene family
In plants, the amino acids tyrosine and phenylalanine are synthesized from arogenate by arogenate dehydrogenase and arogenate dehydratase, respectively, with the relative flux to each being tightly controlled. Here the characterization of a maize opaque endosperm mutant (mto140), which also shows retarded vegetative growth, is described The opaque phenotype co-segregates with a Mutator transposon insertion in an arogenate dehydrogenase gene (zmAroDH-1) and this led to the characterization of the four-member family of maize arogenate dehydrogenase genes (zmAroDH-1–zmAroDH-4) which share highly similar sequences. A Mutator insertion at an equivalent position in AroDH-3, the most closely related family member to AroDH-1, is also associated with opaque endosperm and stunted vegetative growth phenotypes. Overlapping but differential expression patterns as well as subtle mutant effects on the accumulation of tyrosine and phenylalanine in endosperm, embryo, and leaf tissues suggest that the functional redundancy of this gene family provides metabolic plasticity for the synthesis of these important amino acids. mto140/arodh-1 seeds shows a general reduction in zein storage protein accumulation and an elevated lysine phenotype typical of other opaque endosperm mutants, but it is distinct because it does not result from quantitative or qualitative defects in the accumulation of specific zeins but rather from a disruption in amino acid biosynthesis
Biocompatibility of Graphene Oxide
Herein, we report the effects of graphene oxides on human fibroblast cells and mice with the aim of investigating graphene oxides' biocompatibility. The graphene oxides were prepared by the modified Hummers method and characterized by high-resolution transmission electron microscope and atomic force microscopy. The human fibroblast cells were cultured with different doses of graphene oxides for day 1 to day 5. Thirty mice divided into three test groups (low, middle, high dose) and one control group were injected with 0.1, 0.25, and 0.4 mg graphene oxides, respectively, and were raised for 1 day, 7 days, and 30 days, respectively. Results showed that the water-soluble graphene oxides were successfully prepared; graphene oxides with dose less than 20 μg/mL did not exhibit toxicity to human fibroblast cells, and the dose of more than 50 μg/mL exhibits obvious cytotoxicity such as decreasing cell adhesion, inducing cell apoptosis, entering into lysosomes, mitochondrion, endoplasm, and cell nucleus. Graphene oxides under low dose (0.1 mg) and middle dose (0.25 mg) did not exhibit obvious toxicity to mice and under high dose (0.4 mg) exhibited chronic toxicity, such as 4/9 mice death and lung granuloma formation, mainly located in lung, liver, spleen, and kidney, almost could not be cleaned by kidney. In conclusion, graphene oxides exhibit dose-dependent toxicity to cells and animals, such as inducing cell apoptosis and lung granuloma formation, and cannot be cleaned by kidney. When graphene oxides are explored for in vivo applications in animal or human body, its biocompatibility must be considered
Atmospheric River Tracking Method Intercomparison Project (ARTMIP): project goals and experimental design
The Atmospheric River Tracking Method Intercomparison Project
(ARTMIP) is an international collaborative effort to understand and quantify
the uncertainties in atmospheric river (AR) science based on detection
algorithm alone. Currently, there are many AR identification and tracking
algorithms in the literature with a wide range of techniques and conclusions.
ARTMIP strives to provide the community with information on different
methodologies and provide guidance on the most appropriate algorithm for a
given science question or region of interest. All ARTMIP participants will
implement their detection algorithms on a specified common dataset for a
defined period of time. The project is divided into two phases: Tier 1 will
utilize the Modern-Era Retrospective analysis for Research and Applications,
version 2 (MERRA-2) reanalysis from January 1980 to June 2017 and will be
used as a baseline for all subsequent comparisons. Participation in Tier 1 is
required. Tier 2 will be optional and include sensitivity studies designed
around specific science questions, such as reanalysis uncertainty and climate
change. High-resolution reanalysis and/or model output will be used wherever
possible. Proposed metrics include AR frequency, duration, intensity, and
precipitation attributable to ARs. Here, we present the ARTMIP experimental
design, timeline, project requirements, and a brief description of the
variety of methodologies in the current literature. We also present results
from our 1-month proof-of-concept trial run designed to illustrate the
utility and feasibility of the ARTMIP project
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