242 research outputs found
Influence of carrier-carrier and carrier-phonon correlations on optical absorption and gain in quantum-dot systems
A microscopic theory is used to study the optical properties of semiconductor
quantum dots. The dephasing of a coherent excitation and line-shifts of the
interband transitions due to carrier-carrier Coulomb interaction and
carrier-phonon interaction are determined from a quantum kinetic treatment of
correlation processes. We investigate the density dependence of both mechanisms
and clarify the importance of various dephasing channels involving the
localized and delocalized states of the system.Comment: 12 pages, 10 figure
Repetitive proteins from the flagellar cytoskeleton of African trypanosomes are diagnostically useful antigens
Trypanosome infection of mammalian hosts leads, within days, to a strong early response against a small, distinct number of parasite proteins. One of these proteins is the variable surface glycoprotein (VSG). Most of the others are apparently non-variable, intracellular trypanosome proteins. Two of these antigens I2 and I17 are now characterized at the molecular level. Both exhibit a highly repetitive amino acid sequence organization, but they show no sequence similarity either to each other or to any other proteins known to date. Preliminary serological analyses indicate that both allow the early, sensitive and specific detection of infections with different species of trypanosomatids, making them interesting candidates for the development of diagnostic tools for trypanosomiasis detectio
Repetitive proteins from the flagellar cytoskeleton of African trypanosomes are diagnostically useful antigens
Trypanosome infection of mammalian hosts leads, within days, to a strong early response against a small, distinct number of parasite proteins. One of these proteins is the variable surface glycoprotein (VSG). Most of the others are apparently non-variable, intracellular trypanosome proteins. Two of these antigens I2 and I17 are now characterized at the molecular level. Both exhibit a highly repetitive amino acid sequence organization, but they show no sequence similarity either to each other or to any other proteins known to date. Preliminary serological analyses indicate that both allow the early, sensitive and specific detection of infections with different species of trypanosomatids, making them interesting candidates for the development of diagnostic tools for trypanosomiasis detection
Spin-dependent thermoelectric transport in HgTe/CdTe quantum wells
We analyze thermally induced spin and charge transport in HgTe/CdTe quantum
wells on the basis of the numerical non-equilibrium Green's function technique
in the linear response regime. In the topologically non-trivial regime, we find
a clear signature of the gap of the edge states due to their finite overlap
from opposite sample boundaries -- both in the charge Seebeck and spin Nernst
signal. We are able to fully understand the physical origin of the
thermoelectric transport signatures of edge and bulk states based on simple
analytical models. Interestingly, we derive that the spin Nernst signal is
related to the spin Hall conductance by a Mott-like relation which is exact to
all orders in the temperature difference between the warm and the cold
reservoir.Comment: 11 pages, 13 figures, submitted to PR
Identification and characterization of two repetitive non-variable antigens from African trypanosomes which are recognized early during infection
The present paper describes two repetitive proteins representing common antigens of African trypanosomes which are non-variant and which are recognized early in infection by the host immune system. These antigens were identified by their ability to immunoreact with bovine serum taken during the early phase of a cyclic trypanosomal infection. Screening of a cDNA library from T. b. gambiense with such early infection serum identified a protein which contains a repetitive motif consisting of 68 amino acid repeat units (GM6). Immunofluorescence and immunogold electron microscopy revealed that GM6 is located on fibres which connect the microtubules of the membrane skeleton with the flagellum. A second repetitive antigen detected by this serum is MARP1 (microtubule-associated repetitive protein 1), a protein previously characterized in this laboratory as a high-molecular weight component of the membrane skeleton, which consists of more than 50 tandemly repeated, near-identical 38 amino acid repeat units. Beta-galactosidase fusion products of both proteins demonstrated a strong immunoreactivity with sera from T. b. brucei and T. congolense-infected cattle. The result from this preliminary immunological evaluation indicates a high immunodiagnostic sensititivy (90%) of the two recombinant antigens which make them interesting candidates for immunodiagnosis of trypanosomiasis in cattl
Identification and characterization of two repetitive non-variable antigens from African trypanosomes which are recognized early during infection
The present paper describes two repetitive proteins representing common antigens of African trypanosomes which are non-variant and which are recognized early in infection by the host immune system. These antigens were identified by their ability to immunoreact with bovine serum taken during the early phase of a cyclic trypanosomal infection. Screening of a cDNA library from T. b. gambiense with such early infection serum identified a protein which contains a repetitive motif consisting of 68 amino acid repeat units (GM6). Immunofluorescence and immunogold electron microscopy revealed that GM6 is located on fibres which connect the microtubules of the membrane skeleton with the flagellum. A second repetitive antigen detected by this serum is MARP1 (microtubule-associated repetitive protein 1), a protein previously characterized in this laboratory as a high-molecular weight component of the membrane skeleton, which consists of more than 50 tandemly repeated, near-identical 38 amino acid repeat units. Beta-galactosidase fusion products of both proteins demonstrated a strong immunoreactivity with sera from T. b. brucei and T. congolense-infected cattle. The result from this preliminary immunological evaluation indicates a high immunodiagnostic sensititivy (90%) of the two recombinant antigens which make them interesting candidates for immunodiagnosis of trypanosomiasis in cattle
Nonlinear Dynamics of the Perceived Pitch of Complex Sounds
We apply results from nonlinear dynamics to an old problem in acoustical
physics: the mechanism of the perception of the pitch of sounds, especially the
sounds known as complex tones that are important for music and speech
intelligibility
Reconnaissance Basement Geology and Tectonics of South Zealandia
We report new U‐Pb zircon ages, geochemical and isotopic data for Mesozoic igneous rocks, and new seismic interpretations of mostly submerged South Zealandia (1.5 Mkm2). We use these data, along with existing geological and geophysical data sets, to refine the extent and nature of geological units. Our new 1:25 M geological map of South Zealandia provides a regional framework to investigate the rifting and breakup that formed Zealandia, Earth's most submerged continent. Samples of prerift (pre‐100 Ma) plutonic rocks can be matched with on‐land New Zealand igneous suites and indicate an east‐west strike for the subduction‐related 260 to 105‐Ma Median Batholith across the Campbell Plateau. The plutonic chronology of formerly contiguous plutonic rocks in West Antarctica reveals similar pulses and lulls to the Median Batholith. Contrary to previous interpretations, the Median Batholith does not coincide with the 1,600‐km‐long Campbell Magnetic Anomaly System. Instead we interpret the continental magnetic anomalies to represent a mainly mafic igneous unit, whose shape and extent is controlled by synrift structures related to Gondwana breakup. Correlatives of some of these unsampled igneous rocks may be exposed as circa 85 Ma alkalic volcanic rocks on the Chatham Islands. Extension directions varied by up to 65° from 100 to 80 Ma, and we suggest this allowed this large area to thin considerably before final rupture to form new oceanic crust. Synrift (90–80 Ma) structures cut the oroclinal bend in southern South Island and support a pre‐early Late Cretaceous age of orocline formation.The work was supported by Core Research Funding to GNS Science by the New Zealand Government Ministry of Business, Employment and Innovation
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