1,271 research outputs found

    Comment on "Quantum linear Boltzmann equation with finite intercollision time"

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    Inconsistencies are pointed out in a recent proposal [L. Diosi, Phys. Rev. A 80, 064104 (2009); arXiv:0905.3908v1] for a quantum version of the classical linear Boltzmann equation.Comment: 3 pages; v3: corresponds to published versio

    Molecular Feshbach dissociation as a source for motionally entangled atoms

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    We describe the dissociation of a diatomic Feshbach molecule due to a time-varying external magnetic field in a realistic trap and guide setting. An analytic expression for the asymptotic state of the two ultracold atoms is derived, which can serve as a basis for the analysis of dissociation protocols to generate motionally entangled states. For instance, the gradual dissociation by sequences of magnetic field pulses may delocalize the atoms into macroscopically distinct wave packets, whose motional entanglement can be addressed interferometrically. The established relation between the applied magnetic field pulse and the generated dissociation state reveals that square-shaped magnetic field pulses minimize the momentum spread of the atoms. This is required to control the detrimental influence of dispersion in a recently proposed experiment to perform a Bell test in the motion of the two atoms [C. Gneiting and K. Hornberger, Phys. Rev. Lett. 101, 260503 (2008)].Comment: 12 pages, 3 figures; corresponds to published versio

    A comparison of magnetic resonance imaging and neuropsychological examination in the diagnostic distinction of Alzheimer’s disease and behavioral variant frontotemporal dementia

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    The clinical distinction between Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD) remains challenging and largely dependent on the experience of the clinician. This study investigates whether objective machine learning algorithms using supportive neuroimaging and neuropsychological clinical features can aid the distinction between both diseases. Retrospective neuroimaging and neuropsychological data of 166 participants (54 AD; 55 bvFTD; 57 healthy controls) was analyzed via a Naïve Bayes classification model. A subgroup of patients (n = 22) had pathologically-confirmed diagnoses. Results show that a combination of gray matter atrophy and neuropsychological features allowed a correct classification of 61.47% of cases at clinical presentation. More importantly, there was a clear dissociation between imaging and neuropsychological features, with the latter having the greater diagnostic accuracy (respectively 51.38 vs. 62.39%). These findings indicate that, at presentation, machine learning classification of bvFTD and AD is mostly based on cognitive and not imaging features. This clearly highlights the urgent need to develop better biomarkers for both diseases, but also emphasizes the value of machine learning in determining the predictive diagnostic features in neurodegeneration

    A Foot in the Door: The Annotated Checklist

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    The role of the reading specialist has traditionally been perceived as broader in some scope than that of just a remedial teacher. Ideally, the reading specialist becomes a resource upon which all classroom teachers can rely. Some recent evidence (IRA, 1976) seems to support the assumption that this ideal is, at least to some degree, a reality at the elementary level

    Testing spontaneous localization theories with matter-wave interferometry

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    We propose to test the theory of continuous spontaneous localization (CSL) in an all-optical time-domain Talbot-Lau interferometer for clusters with masses exceeding 1000000 amu. By assessing the relevant environmental decoherence mechanisms, as well as the growing size of the particles relative to the grating fringes, we argue that it will be feasible to test the quantum superposition principle in a mass range excluded by recent estimates of the CSL effect.Comment: 4 pages, 3 figures; corresponds to published versio

    Analysis of the Effects of Spatiotemporal Demand Data Aggregation Methods on Distance and Volume Errors

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    Purpose — Large/stochastic spatiotemporal demand data sets can prove intractable for location optimization problems, motivating the need for aggregation. However, demand aggregation induces errors. Significant theoretical research has been performed related to the modifiable areal unit problem and the zone definition problem. Minimal research has been accomplished related to the specific issues inherent to spatiotemporal demand data, such as search and rescue (SAR) data. This study provides a quantitative comparison of various aggregation methodologies and their relation to distance and volume based aggregation errors. Design/methodology/approach — This paper introduces and applies a framework for comparing both deterministic and stochastic aggregation methods using distance- and volume-based aggregation error metrics. This paper additionally applies weighted versions of these metrics to account for the reality that demand events are nonhomogeneous. These metrics are applied to a large, highly variable, spatiotemporal demand data set of SAR events in the Pacific Ocean. Comparisons using these metrics are conducted between six quadrat aggregations of varying scales and two zonal distribution models using hierarchical clustering. Findings — As quadrat fidelity increases the distance-based aggregation error decreases, while the two deliberate zonal approaches further reduce this error while using fewer zones. However, the higher fidelity aggregations detrimentally affect volume error. Additionally, by splitting the SAR data set into training and test sets this paper shows the stochastic zonal distribution aggregation method is effective at simulating actual future demands. Originality/value — This study indicates no singular best aggregation method exists, by quantifying trade-offs in aggregation-induced errors practitioners can utilize the method that minimizes errors most relevant to their study. Study also quantifies the ability of a stochastic zonal distribution method to effectively simulate future demand data

    PCN28 REVIEW OF ECONOMIC APPRAISALS OF CHEMOTHERAPY FOR METASTATIC COLORECTAL CANCER

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    Concept of an ionizing time-domain matter-wave interferometer

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    We discuss the concept of an all-optical and ionizing matter-wave interferometer in the time domain. The proposed setup aims at testing the wave nature of highly massive clusters and molecules, and it will enable new precision experiments with a broad class of atoms, using the same laser system. The propagating particles are illuminated by three pulses of a standing ultraviolet laser beam, which detaches an electron via efficient single photon-absorption. Optical gratings may have periods as small as 80 nm, leading to wide diffraction angles for cold atoms and to compact setups even for very massive clusters. Accounting for the coherent and the incoherent parts of the particle-light interaction, we show that the combined effect of phase and amplitude modulation of the matter waves gives rise to a Talbot-Lau-like interference effect with a characteristic dependence on the pulse delay time.Comment: 25 pages, 5 figure
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