289 research outputs found
Far Infrared Slab Lensing and Subwavelength Imaging in Crystal Quartz
We examine the possibility of using negative refraction stemming from the
phonon response in an anisotropic crystal to create a simple slab lens with
plane parallel sides, and show that imaging from such a lens should be possible
at room temperature despite the effects of absorption that are inevitably
present due to phonon damping. In particular, we consider the case of crystal
quartz, a system for which experimental measurements consistent with all-angle
negative refraction have already been demonstrated. Furthermore, we investigate
the possibility of subwavelength imaging from such materials, and show that it
should be possible for certain configurations.Comment: 12 pages, 10 figure
Single standard calibration and data processing in flow injection titration based on concentration gradients
This paper describes use of gradients of concentration generated in
flow injection (FI) systems to perform determinations based on points where the concentration of titrant and analyte are at stoichiometric ratio. Two procedures were developed. In one procedure the titrant is injected in a FI manifold and merges with
the sample which is continuously pumped towards the detector. In the other procedure the sample is injected and merged with the titrant which is continuously pumped. Both techniques make use of concentration gradients of the sample or titrant generated in FI
manifolds that contain a mixing chamber. This gradient is calibrated employing only one standard solution (usually the titrant) in order to convert any detector signal, obtained in the
elapsed time after injection, to instantaneous concentration values. The flow system is microcomputer controlled and data are treated to locate points where the concentration of titrant and analyte are at the stoichiometric ratio. These points are found in abrupt changes
of the signal × concentration curves obtained in the presence of the reaction. The method has been evaluated for determination of Fe(II) and acetic acid by spectrophotometric and conductimetric detection, respectively. Results show a mean relative standard deviation lower than 1%, an average accuracy of 1% and a high
sampling processing capability (40 to 60 samples per hour)
THE TRANSPULMONARY GRADIENT BUT NOT THE SYSTOLIC OR MEAN PULMONARY ARTERIAL PRESSURE CORRELATES WITH THE WALL THICKNESS OF PERIPHERAL PULMONARY ARTERIES AND VEINS IN PATIENTS WITH CHRONIC HEART FAILURE
Congenital Destructive Hemispheric Lesions And Epilepsy: Clinical Features And Relevance Of Associated Hippocampal Atrophy.
We studied the clinical, EEG and MRI findings in 19 patients with epilepsy secondary to congenital destructive hemispheric insults. Patients were divided in two groups: 10 with cystic lesions (group 1), and 9 with atrophic lesions (group 2). Seizure and EEG features, as well as developmental sequelae were similar between the two groups, except for the finding that patients of group 2 more commonly presented seizures with more than one semiological type. MRI showed hyperintense T2 signal extending beyond the lesion in almost all patients of both groups, and it was more diffuse in group 2. Associated hippocampal atrophy (HA) was observed in 70% of group 1 patients and 77.7% of group 2, and it was not correlated with duration of epilepsy or seizure frequency. There was a good concordance between HA and electroclinical localization. The high prevalence of associated HA in both groups suggests a common pathogenesis with the more obvious lesion. Our findings indicate that in some of these patients with extensive destructive lesions, there may be a more circumscribed epileptogenic area, particularly in those with cystic lesions and HA, leading to a potential rationale for effective surgical treatment.58990-100
A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients
The benefit of postoperative adjuvant chemotherapy in patients with Dukes' B colorectal cancer is still uncertain and its routine use is not recommended. The five-year relapse rate is approximately 25-40% and the identification of patients at high risk of recurrence would represent an important strategy for the use of adjuvant chemotherapy. We retrospectively analyzed gene expression profiles in frozen tumor specimens from patients with Dukes' B colorectal cancer by using high density oligonucleotide microarrays. Our results show a subset of 48 genes differentially expressed with an associated probability <0.001 in the t-test. Another statistical procedure based on the Fisher criterion resulted in 11 genes able to separate both groups. We selected the 8 genes present in both subsets. The differential expression of five genes (CHD2, RPS5, ZNF148, BRI3 and MGC23401) in colon cancer progression was confirmed by real-time PCR in an independent set of patients of Dukes' B and C stages
Construção de novas linhagens de Saccharomyces cerevisiae capazes de utilizar xilose para a produção de bioetanol.
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