998 research outputs found
Mobile applications for weather and climate information: their use and potential for smallholder farmers
Mobile phones are increasingly being used to provide smallholder farmers with agricultural
and related information. There is currently great interest in their scope to communicate
climate and weather information. Farmers consistently identify demand for weather
information and whilst ICTs may be one way of delivering this at scale there are concerns that
this should not be seen as a panacea. At a time when there have been a range of initiatives and
projects that have been implemented this paper seeks to draw lessons and identify key
considerations to inform the development of future mobile applications to provide climate
services to smallholder farmers. A literature review, interviews with key informants and
experts and 15 case study reviews were conducted. This focused principally on Sub Saharan
Africa but included some examples from India.
Despite numerous initiatives few have developed fully beyond the pilot stage and few have
been evaluated. Some of the provision to date has been of questionable value to farmers. A
key observation is that relatively little attention has been paid in design, to the needs for and
use of both the information and technology by farmers, and few attempts made to differentiate
provision according to gender and other demographic variables. Other factors contributing to
success included communications approaches, which are interactive and/or involve trusted
intermediaries who can add context to and help interpret more complex information.
Providing weather information alongside other services as ‘bundles’ and in conjunction with
complementary communications approaches appears to work well. An important challenge is
how to meet farmers’ needs for location specific, timely and relevant information in
economically sustainable ways. More widely there are challenges in achieving successful
business models and potential conflicts between initiatives driven by mobile network
operators and public goals.
The study identified areas of considerable potential which include: the use of increasingly
available mobile data connections to ensure locally relevant content is available to farmers in
timely fashion (including both historical climate information and forecasts); development of
participatory decision making tools to enable farmers to interpret information for their own
contexts and consider implications and management options; use of visual applications and
participatory video on mobile devices to enhance learning and advisory services for farmers; the potential for increased feedback between farmers and service providers as well as
increased knowledge sharing between farmers provided by the use of social media
Speckle Statistics in Adaptively Corrected Images
(abridged) Imaging observations are generally affected by a fluctuating
background of speckles, a particular problem when detecting faint stellar
companions at small angular separations. Knowing the distribution of the
speckle intensities at a given location in the image plane is important for
understanding the noise limits of companion detection. The speckle noise limit
in a long-exposure image is characterized by the intensity variance and the
speckle lifetime. In this paper we address the former quantity through the
distribution function of speckle intensity. Previous theoretical work has
predicted a form for this distribution function at a single location in the
image plane. We developed a fast readout mode to take short exposures of
stellar images corrected by adaptive optics at the ground-based UCO/Lick
Observatory, with integration times of 5 ms and a time between successive
frames of 14.5 ms ( m). These observations temporally
oversample and spatially Nyquist sample the observed speckle patterns. We show,
for various locations in the image plane, the observed distribution of speckle
intensities is consistent with the predicted form. Additionally, we demonstrate
a method by which and can be mapped over the image plane. As the
quantity is proportional to the PSF of the telescope free of random
atmospheric aberrations, this method can be used for PSF calibration and
reconstruction.Comment: 7 pages, 4 figures, ApJ accepte
Evidence of two viscous relaxation processes in the collective dynamics of liquid lithium
New inelastic X-ray scattering experiments have been performed on liquid
lithium in a wide wavevector range. With respect to the previous measurements,
the instrumental resolution, improved up to 1.5 meV, allows to accurately
investigate the dynamical processes determining the observed shape of the the
dynamic structure factor, . A detailed analysis of the lineshapes
shows the co-existence of relaxation processes with both a slow and a fast
characteristic timescales, and therefore that pictures of the relaxation
mechanisms based on a simple viscoelastic model must be abandoned.Comment: 5 pages, 4 .PS figure
Strong coupling between magnetic and structural order parameters in SrFe2As2
X-ray and Neutron diffraction as well as muon spin relaxation and M\"ossbauer
experiments performed on SrFeAs polycrystalls confirm a sharp first
order transition at ,K corresponding to an orthorhombic phase
distortion and to a columnar antiferromagnetic Fe ordering with a propagation
vector (1,0,1), and a larger distortion and larger size of the ordered moment
than reported for BaFeAs. The structural and the magnetic order
parameters present an remarkable similarity in their temperature dependence
from down to low temperatures, showing that both phenomena are intimately
connected. Accordingly, the size of the ordered Fe moments scale with the
lattice distortion when going from SrFeAs to BaFeAs.
Full-potential band structure calculations confirm that the columnar magnetic
order and the orthorhombic lattice distortion are intrinsically tied to each
other.Comment: 10 pages, 4 figure
Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinoma.
Background: The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC)
remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by studying multiple areas of the same liver from patients with HCC.
Methods: We compared the gene signature of whole liver tissue (WLT) versus laser capture-microdissected (LCM)
hepatocytes along with the intrahepatic expression of HBV. Gene expression profiling was performed on up to 17 WLT specimens obtained at various distances from the tumor center from individual livers of 11 patients with HCC and on selected LCM samples. HBV markers in liver and serum were determined by real-time polymerase chain reaction (PCR)and confocal immunofluorescence.
Results: Analysis of 5 areas of the liver showed a sharp change in gene expression between the immediate perilesional area and tumor periphery that correlated with a significant decrease in the intrahepatic expression of HB surface antigen (HBsAg). The tumor was characterized by a large preponderance of down-regulated genes, mostly involved in the
metabolism of lipids and fatty acids, glucose, amino acids and drugs, with down-regulation of pathways involved in the activation of PXR/RXR and PPARα/RXRα nuclear receptors, comprising PGC-1α and FOXO1, two key regulators
critically involved not only in the metabolic functions of the liver but also in the life cycle of HBV, acting as essential transcription factors for viral gene expression. These findings were confirmed by gene expression of microdissected
hepatocytes. Moreover, LCM of malignant hepatocytes also revealed up-regulation of unique genes associated with
cancer and signaling Pathways, including two novel HCC-associated cancer testis antigen genes, NUF2 and TTK.
Conclusions: Integrated gene expression profiling of whole liver tissue with that of microdissected hepatocytes
demonstrated that HBV-associated HCC is characterized by a metabolism switch-off and by a significant reduction in
HBsAg. LCM proved to be a critical tool to validate gene signatures associated with HCC and to identify genes that may play a role in hepatocarcinogenesis, opening new perspectives for the discovery of novel diagnostic markers and therapeutic targets
Variation in the Extraction Efficiency of Estradiol and Progesterone in Moist and Lyophilized Feces of the Black Howler Monkey (Alouatta pigra): Alternative Methods
Several fecal steroid extraction techniques have been developed to measure the ovary function in different species of mammals. However, regardless of the method of extraction and the sample type chosen, it has been observed that they can yield results with different percentages of recuperation. The objective of this study was to determine whether the type of substratum, solvent and extraction method used have any influence on the extraction efficiency in the feces of Alouatta pigra (black howler monkey). For this purpose we used two methods: agitation and ebullition. With each method, we utilized moist and lyophilized feces. The validation of radioimmunoassay method was accurate and precise for quantify estradiol and progesterone in lyophilized feces of A. pigra. To both of which ethanol and methanol, absolute and at 80%, were added, besides the hormones 125I-Estradiol and 125I-Progesterone. The extraction efficiency for 125I-Estradiol was from 87.72 ± 3.97 to 41.24 ± 2.67%, and for 125I-Progesterone from 71.15 ± 4.24 to 42.30 ± 1.19% when we used the agitation method. Whereas with the ebullition method, the extraction efficiency for 125I-Estradiol ranged from 86.89 ± 2.66 to 71.68 ± 3.02% and for 125I-Progesterone from 98.31 ± 1.26 to 85.40 ± 1.98%. Due to the differences found in these assays, which depend on the method used, the type of feces employed and the type of solvent added to them, we recommend the ebullition method and the lyophilized feces of A. pigra for extracting the hormones, since in moist feces there may exist variables which might interfere in the quantification of 125I-Estradiol and 125I-Progesterone
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Architecture of on- and off-axis magma bodies at EPR 9°37–40′N and implications for oceanic crustal accretion
Crustal accretion at fast-spreading mid-ocean ridges is believed to be concentrated in a narrow zone up to a few kilometers wide centered beneath the ridge axis. However, there is increasing evidence for off-axis magmatism occurring beyond this narrow zone. Here, we present 3D multichannel seismic (MCS) images from the East Pacific Rise 9°37–40′N extending to 11 km on the ridge flanks. In the axial region, two offset axial magma bodies underlie a small ridge-axis discontinuity at ∼9°37′N, displaying an overlapping geometry similar to that of the seafloor structures above. On the ridge flanks, a series of off-axis magma lenses (OAML) are imaged: they are located 2–10 km from the ridge axis, at 700 to 1520 ms two-way travel time below seafloor (bsf) (∼1.6 to 4.5 km bsf), with variable areas ranging from 0.5 km2 to 5.2 km2. The largest body is centered 4 km east of the ridge axis and is composed of a large, continuous, flat-topped lens and a series of small, discontinuous, westward-dipping bodies along its western edge. The flat crest of the OAML lies at approximately the same depth beneath layer 2A as the axial magma lens and we infer that this OAML has formed by aggregation of ascending melts that accumulate at the base of the sheeted dike section. A cluster of reflections underlying the OAML at 1260–1510 ms bsf are observed that may be deeper lenses feeding melts to the upper lens. This largest OAML is associated with Moho travel time anomalies of 120–260 ms within a zone that extends up to 2 km from the edge of the OAML, suggesting a lower crust that is partially molten with lower crustal velocities reduced by 8–18% and/or thicker than normal by up to 1 km. Local volcanic edifices are found above two of the three OAMLs imaged in our study area and are inferred to be the eruptive products of the OAMLs. From the volume of these edifices and the Moho travel time anomalies we estimate the potential contribution of off-axis magmatism to the total volume of the crust to be ∼0.01–3%. The OAMLs imaged in our study area are present over roughly the same distance range as the zone of formation of near-axis seamounts. We speculate that OAMLs and the volcanic edifices found above them are small-scale manifestations of the off-axis magmatism that gives rise to near-axis seamounts
Electrical Material Property Measurements using a Free-Field, Ultra-Wideband System [Dielectric Measurements]
We present nondestructive measurements of material properties using TEM horn antennas and an ultra-wideband measurement system. Time-domain gating and genetic algorithms are used to process the data and extract the dielectric properties of the material under test
Fabrication and assessment of bifunctional electrospun poly(L-lactic acid) scaffolds with bioglass and zinc oxide nanoparticles for bone tissue engineering
Electrospun scaffolds based on poly(L-lactic acid) (PLLA) with bioglass (n-BG) and zinc oxide (n-ZnO), and mixture of both, were developed to design bifunctional biomaterials with enhanced bioactive and biocidal properties. The presence of n-BG increased the fiber diameter of the pure PLA from 1.5 ± 0.3 μm to 3.0 ± 0.8 μm for 20 wt%. ZnO and the mixed nanoparticles did not significantly affect the morphology. The mechanical properties decreased with the presence of nanoparticles. Scaffolds based on PLA/n-BG promoted hydroxyapatite (HA) formation in simulated body fluid (SBF) that was inhibited with the presence of ZnO. Notably, mixed particles produced bioactivity although at longer times. The incorporation of n-ZnO produced a biocidal capacity against S. aureus in the polymeric scaffold, reaching a viability reduction of 60 % after 6 h of exposure. When both types of nanoparticles were combined, the bacterial viability reduction was 30 %. Pure PLA scaffolds and the composites with n-BG showed good ST-2 bone marrow-derived cell line viability, scaffolds with n-BG (pure or mixture) presented lower viability. Results validated the use of both n-BG and n-ZnO fillers for the development of novel bifunctional PLA-based scaffolds with both bioactive and biocidal properties for bone tissue engineering applications.P.A. Zapata acknowledge the financial support of Direccion de Investigacion Científica y Tecnologica, Universidad de Santiago de Chile (DICYT) project: 052241ZR_DAS. D. Canales thanks the financial support of FONDECYT under postdoctoral project No. 3210810. Finally, D. Canales is immensely grateful to Katharina Schuhladen, Sonja Kuth, Lena Vogt, Irem Unalam, and Florian Ruther, members of Institute of Biomaterials of University of Erlangen-Nuremberg, for their support in the mechanical and biological analysis
Density fluctuations and single-particle dynamics in liquid lithium
The single-particle and collective dynamical properties of liquid lithium
have been evaluated at several thermodynamic states near the triple point. This
is performed within the framework of mode-coupling theory, using a
self-consistent scheme which, starting from the known static structure of the
liquid, allows the theoretical calculation of several dynamical properties.
Special attention is devoted to several aspects of the single-particle
dynamics, which are discussed as a function of the thermodynamic state. The
results are compared with those of Molecular Dynamics simulations and other
theoretical approaches.Comment: 31 pages (in preprint format), 14 figures. Submitted to Phys. Rev.
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