998 research outputs found

    Mobile applications for weather and climate information: their use and potential for smallholder farmers

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    Mobile phones are increasingly being used to provide smallholder farmers with agricultural and related information. There is currently great interest in their scope to communicate climate and weather information. Farmers consistently identify demand for weather information and whilst ICTs may be one way of delivering this at scale there are concerns that this should not be seen as a panacea. At a time when there have been a range of initiatives and projects that have been implemented this paper seeks to draw lessons and identify key considerations to inform the development of future mobile applications to provide climate services to smallholder farmers. A literature review, interviews with key informants and experts and 15 case study reviews were conducted. This focused principally on Sub Saharan Africa but included some examples from India. Despite numerous initiatives few have developed fully beyond the pilot stage and few have been evaluated. Some of the provision to date has been of questionable value to farmers. A key observation is that relatively little attention has been paid in design, to the needs for and use of both the information and technology by farmers, and few attempts made to differentiate provision according to gender and other demographic variables. Other factors contributing to success included communications approaches, which are interactive and/or involve trusted intermediaries who can add context to and help interpret more complex information. Providing weather information alongside other services as ‘bundles’ and in conjunction with complementary communications approaches appears to work well. An important challenge is how to meet farmers’ needs for location specific, timely and relevant information in economically sustainable ways. More widely there are challenges in achieving successful business models and potential conflicts between initiatives driven by mobile network operators and public goals. The study identified areas of considerable potential which include: the use of increasingly available mobile data connections to ensure locally relevant content is available to farmers in timely fashion (including both historical climate information and forecasts); development of participatory decision making tools to enable farmers to interpret information for their own contexts and consider implications and management options; use of visual applications and participatory video on mobile devices to enhance learning and advisory services for farmers; the potential for increased feedback between farmers and service providers as well as increased knowledge sharing between farmers provided by the use of social media

    Speckle Statistics in Adaptively Corrected Images

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    (abridged) Imaging observations are generally affected by a fluctuating background of speckles, a particular problem when detecting faint stellar companions at small angular separations. Knowing the distribution of the speckle intensities at a given location in the image plane is important for understanding the noise limits of companion detection. The speckle noise limit in a long-exposure image is characterized by the intensity variance and the speckle lifetime. In this paper we address the former quantity through the distribution function of speckle intensity. Previous theoretical work has predicted a form for this distribution function at a single location in the image plane. We developed a fast readout mode to take short exposures of stellar images corrected by adaptive optics at the ground-based UCO/Lick Observatory, with integration times of 5 ms and a time between successive frames of 14.5 ms (λ=2.2\lambda=2.2 μ\mum). These observations temporally oversample and spatially Nyquist sample the observed speckle patterns. We show, for various locations in the image plane, the observed distribution of speckle intensities is consistent with the predicted form. Additionally, we demonstrate a method by which IcI_c and IsI_s can be mapped over the image plane. As the quantity IcI_c is proportional to the PSF of the telescope free of random atmospheric aberrations, this method can be used for PSF calibration and reconstruction.Comment: 7 pages, 4 figures, ApJ accepte

    Evidence of two viscous relaxation processes in the collective dynamics of liquid lithium

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    New inelastic X-ray scattering experiments have been performed on liquid lithium in a wide wavevector range. With respect to the previous measurements, the instrumental resolution, improved up to 1.5 meV, allows to accurately investigate the dynamical processes determining the observed shape of the the dynamic structure factor, S(Q,ω)S(Q,\omega). A detailed analysis of the lineshapes shows the co-existence of relaxation processes with both a slow and a fast characteristic timescales, and therefore that pictures of the relaxation mechanisms based on a simple viscoelastic model must be abandoned.Comment: 5 pages, 4 .PS figure

    Strong coupling between magnetic and structural order parameters in SrFe2As2

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    X-ray and Neutron diffraction as well as muon spin relaxation and M\"ossbauer experiments performed on SrFe2_2As2_2 polycrystalls confirm a sharp first order transition at T0=205T_0 = 205,K corresponding to an orthorhombic phase distortion and to a columnar antiferromagnetic Fe ordering with a propagation vector (1,0,1), and a larger distortion and larger size of the ordered moment than reported for BaFe2_2As2_2. The structural and the magnetic order parameters present an remarkable similarity in their temperature dependence from T0T_0 down to low temperatures, showing that both phenomena are intimately connected. Accordingly, the size of the ordered Fe moments scale with the lattice distortion when going from SrFe2_2As2_2 to BaFe2_2As2_2. Full-potential band structure calculations confirm that the columnar magnetic order and the orthorhombic lattice distortion are intrinsically tied to each other.Comment: 10 pages, 4 figure

    Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinoma.

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    Background: The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by studying multiple areas of the same liver from patients with HCC. Methods: We compared the gene signature of whole liver tissue (WLT) versus laser capture-microdissected (LCM) hepatocytes along with the intrahepatic expression of HBV. Gene expression profiling was performed on up to 17 WLT specimens obtained at various distances from the tumor center from individual livers of 11 patients with HCC and on selected LCM samples. HBV markers in liver and serum were determined by real-time polymerase chain reaction (PCR)and confocal immunofluorescence. Results: Analysis of 5 areas of the liver showed a sharp change in gene expression between the immediate perilesional area and tumor periphery that correlated with a significant decrease in the intrahepatic expression of HB surface antigen (HBsAg). The tumor was characterized by a large preponderance of down-regulated genes, mostly involved in the metabolism of lipids and fatty acids, glucose, amino acids and drugs, with down-regulation of pathways involved in the activation of PXR/RXR and PPARα/RXRα nuclear receptors, comprising PGC-1α and FOXO1, two key regulators critically involved not only in the metabolic functions of the liver but also in the life cycle of HBV, acting as essential transcription factors for viral gene expression. These findings were confirmed by gene expression of microdissected hepatocytes. Moreover, LCM of malignant hepatocytes also revealed up-regulation of unique genes associated with cancer and signaling Pathways, including two novel HCC-associated cancer testis antigen genes, NUF2 and TTK. Conclusions: Integrated gene expression profiling of whole liver tissue with that of microdissected hepatocytes demonstrated that HBV-associated HCC is characterized by a metabolism switch-off and by a significant reduction in HBsAg. LCM proved to be a critical tool to validate gene signatures associated with HCC and to identify genes that may play a role in hepatocarcinogenesis, opening new perspectives for the discovery of novel diagnostic markers and therapeutic targets

    Variation in the Extraction Efficiency of Estradiol and Progesterone in Moist and Lyophilized Feces of the Black Howler Monkey (Alouatta pigra): Alternative Methods

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    Several fecal steroid extraction techniques have been developed to measure the ovary function in different species of mammals. However, regardless of the method of extraction and the sample type chosen, it has been observed that they can yield results with different percentages of recuperation. The objective of this study was to determine whether the type of substratum, solvent and extraction method used have any influence on the extraction efficiency in the feces of Alouatta pigra (black howler monkey). For this purpose we used two methods: agitation and ebullition. With each method, we utilized moist and lyophilized feces. The validation of radioimmunoassay method was accurate and precise for quantify estradiol and progesterone in lyophilized feces of A. pigra. To both of which ethanol and methanol, absolute and at 80%, were added, besides the hormones 125I-Estradiol and 125I-Progesterone. The extraction efficiency for 125I-Estradiol was from 87.72 ± 3.97 to 41.24 ± 2.67%, and for 125I-Progesterone from 71.15 ± 4.24 to 42.30 ± 1.19% when we used the agitation method. Whereas with the ebullition method, the extraction efficiency for 125I-Estradiol ranged from 86.89 ± 2.66 to 71.68 ± 3.02% and for 125I-Progesterone from 98.31 ± 1.26 to 85.40 ± 1.98%. Due to the differences found in these assays, which depend on the method used, the type of feces employed and the type of solvent added to them, we recommend the ebullition method and the lyophilized feces of A. pigra for extracting the hormones, since in moist feces there may exist variables which might interfere in the quantification of 125I-Estradiol and 125I-Progesterone

    Electrical Material Property Measurements using a Free-Field, Ultra-Wideband System [Dielectric Measurements]

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    We present nondestructive measurements of material properties using TEM horn antennas and an ultra-wideband measurement system. Time-domain gating and genetic algorithms are used to process the data and extract the dielectric properties of the material under test

    Fabrication and assessment of bifunctional electrospun poly(L-lactic acid) scaffolds with bioglass and zinc oxide nanoparticles for bone tissue engineering

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    Electrospun scaffolds based on poly(L-lactic acid) (PLLA) with bioglass (n-BG) and zinc oxide (n-ZnO), and mixture of both, were developed to design bifunctional biomaterials with enhanced bioactive and biocidal properties. The presence of n-BG increased the fiber diameter of the pure PLA from 1.5 ± 0.3 μm to 3.0 ± 0.8 μm for 20 wt%. ZnO and the mixed nanoparticles did not significantly affect the morphology. The mechanical properties decreased with the presence of nanoparticles. Scaffolds based on PLA/n-BG promoted hydroxyapatite (HA) formation in simulated body fluid (SBF) that was inhibited with the presence of ZnO. Notably, mixed particles produced bioactivity although at longer times. The incorporation of n-ZnO produced a biocidal capacity against S. aureus in the polymeric scaffold, reaching a viability reduction of 60 % after 6 h of exposure. When both types of nanoparticles were combined, the bacterial viability reduction was 30 %. Pure PLA scaffolds and the composites with n-BG showed good ST-2 bone marrow-derived cell line viability, scaffolds with n-BG (pure or mixture) presented lower viability. Results validated the use of both n-BG and n-ZnO fillers for the development of novel bifunctional PLA-based scaffolds with both bioactive and biocidal properties for bone tissue engineering applications.P.A. Zapata acknowledge the financial support of Direccion de Investigacion Científica y Tecnologica, Universidad de Santiago de Chile (DICYT) project: 052241ZR_DAS. D. Canales thanks the financial support of FONDECYT under postdoctoral project No. 3210810. Finally, D. Canales is immensely grateful to Katharina Schuhladen, Sonja Kuth, Lena Vogt, Irem Unalam, and Florian Ruther, members of Institute of Biomaterials of University of Erlangen-Nuremberg, for their support in the mechanical and biological analysis

    Density fluctuations and single-particle dynamics in liquid lithium

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    The single-particle and collective dynamical properties of liquid lithium have been evaluated at several thermodynamic states near the triple point. This is performed within the framework of mode-coupling theory, using a self-consistent scheme which, starting from the known static structure of the liquid, allows the theoretical calculation of several dynamical properties. Special attention is devoted to several aspects of the single-particle dynamics, which are discussed as a function of the thermodynamic state. The results are compared with those of Molecular Dynamics simulations and other theoretical approaches.Comment: 31 pages (in preprint format), 14 figures. Submitted to Phys. Rev.
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