The Electronic Controls Used in a Search For Fractional Charges in Mercury Drops

At San Francisco State University, we have developed an Automatic Millikan Device (AMI)) for measuring the charge on small drops of Mercury. The device uses a standard atomic physics laboratory Millikan chamber, a piezoelectric driven ink-jet glass dropper, and a laser-photomultiplier system for tracking the motion of the drop. This paper describes the electronic control and error detection system used with the AMO. Signals from this system are sent to a microprocessor which controls the experiment. To this date (Dec 7, 1981), we have measured 175 micrograms of Hg and found no fractional charges in 1.05 x 1020 nucleons

Nurses\u27 Alumnae Association Bulletin, May 1957

Alumnae Notes Committee Reports Digest of Alumnae Meetings Graduation Awards - 1956 Letter from Hong Kong Leukemia Marriages Necrology New Arrivals Physical Advances at Jefferson President\u27s Message School of Nursing Report Two Year Programs in Nursing White Haven Repor

Nurses\u27 Alumnae Association Bulletin, April 1961

Alumnae Meetings 1960 Social Committee Clara Melville Scholarship Fund Bulletin Committee Private Duty Nurse\u27s Section Report of the School of Nursing and Nursing Service Staff Nurses Association Student Activities Personal Items of Interest Expansion of Jefferson Artificial Kidney Unit Medical Work in the Congo Marriages New Arrivals Necrology Annual Giving Fun

Pelaksanaan Kebijaksanaan Pelayanan Kesehatan Gratis Bagi Keluarga Miskin (Gakin) di Rumah Sakit Pemerintahan Provinsi Nusa Tenggara Timur (NTT): Studi Kasus di RSUD Prof Dr Wz Johannes Kupang dan RSUD Kabupaten Timor Tengah Selatan

In accordance to the prompt 100 days Program of the "Kabinet Bersatu" government as to improve the quantity and quality of medical staffs, to develop health insurance for poor families, and to improve basic health services; this study aimed to determme free health services for poor families at class 3 public hospitals. It was a survei conducted in 2 public hospitals, Province Hospital Prof. Dr WZ Johannes in Kupang District and District Hospital of Timor Tengah Selatan (TTS) District in SoE in Nusa Tenggara Timur (NTT) Province. Data were collected by interview to poor and non poor families who ever or bemg seeking treatment to and poor families who never seeking treatment to the public hospttals and also by depth interview to the director and staffs of the hospitals. Depth interview on health or poor cards were done in two health centers in Kupang and TTS Districts, respectively. Results showed that there were still lack of medical doctors, no difference satisfaction for class III patients either who used poor or non poor facilities in both public hospitals, budget for free services in the hospitals was largely deficit so the medic and paramedic staffs did not receive medical fees, and also presence poor families who did not know the advantages of healthy cards to receive free health services at class III public hospitals. For optimal services, it is a need to develop new policy on recruitment and placement of medic and paramedic staffs, including to determine district capabilities in providing insentives, and also community demands for health staffs. And it is a need to provide medical fees for service to poor families to maintain quality of health services in long period

Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.

Background Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus CE in extensive-stage disease small cell lung cancer (ED-SCLC). Methods This exploratory analysis of a phase II study evaluated CXCR4 expression in baseline tumor tissue and peripheral blood CTCs and in post-treatment CTCs. Optimum cutoff values were determined for CTC counts and CXCR4 expression in tumors and CTCs as predictors of survival outcome. Kaplan-Meier estimates and hazard ratios were used to determine biomarker prognostic and predictive values. Results There was weak positive correlation at baseline between CXCR4 expression in tumor tissue and CTCs. Optimum cutoff values were H-score ≥ 210 for CXCR4+ tumor, ≥7% CTCs with CXCR4 expression (CXCR4+ CTCs), and ≥6 CTCs/7.5 mL blood. Baseline H-score for CXCR4+ tumor was not prognostic of progression-free survival (PFS) or overall survival (OS). Baseline CXCR4+ CTCs ≥7% was prognostic of shorter PFS. CTCs ≥6 at baseline and cycle 2, day 1 were prognostic of shorter PFS and OS. None of the biomarkers at their respective optimum cutoffs was predictive of treatment response of LY2510924 plus CE versus CE. Conclusions In patients with ED-SCLC, baseline CXCR4 expression in tumor tissue was not prognostic of survival or predictive of LY2510924 treatment response. Baseline CXCR4+ CTCs ≥7% was prognostic of shorter PFS. CTC count ≥6 at baseline and after 1 cycle of treatment were prognostic of shorter PFS and OS

Arkansas Range Extensions of the Eastern Small-Footed Bat (Myotis leibii) and Northern Long-Eared Bat (Myotisseptentrionalis) and Additional County Records for the Silver-Haired Bat (Lasionycteris noctivagans), Hoary Bat (Lasiurus cinereus), Southeastern Bat (Myotis austroriparius), and Rafinesque\u27s Big-Eared Bat (Plecotus rafinesquii)

We continued field studies of bats in non-cave regions of Arkansas from 1989 to present and utilized specimens submitted to the Arkansas Department of Health Rabies Laboratory to establish Arkansas range extensions for the eastern smallfooted bat (Myotis leibii) and northern long-eared bat (Myotisseptentrionalis). In addition, we documented additional county records for the silver-haired bat (Lasionycteris noctivagans), hoary bat (Lasiurus cinereus), southeastern bat (Myotis austroriparius), and Rafinesque\u27s big-eared bat (Plecotus rafinesquii)

Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children

AbstractBackgroundPreterm (PT) children show early cognitive and language deficits and display altered cortical connectivity for language compared to term (T) children. Developmentally, functional connectivity networks become more segregated and integrated, through the weakening of short-range and strengthening of long-range connections.MethodsLongitudinal intrinsic connectivity distribution (ICD) values were assessed in PT (n=13) compared to T children (n=12) at ages 8 vs. 16 using a Linear Mixed Effects model. Connectivity values in regions generated by the group×age interaction analysis were then correlated to scores on full IQ (FSIQ), verbal IQ (VIQ), verbal comprehension IQ (VCIQ), performance IQ (PIQ), Peabody picture vocabulary test—revised (PPVT­R), and Rapid Naming Composite (RDRL_Cmp).ResultsNine regions were generated by the group×age interaction analysis. PT connectivity significantly increased over time in all but two regions, and they ultimately displayed greater relative connectivity at age 16 than Ts in all areas except the left occipito-temporal cortex (OTC). PTs underwent significant connectivity reductions in the left OTC, which corresponded with worse performance on FSIQ, VIQ, and PIQ. These findings differed from Ts, who did not undergo any significant changes in connectivity over time.ConclusionsThese findings suggest that the developmental alterations in connectivity in PT children at adolescence are both pervasive and widespread. The persistent and worsening cognitive and language deficits noted in the PT subjects may be attributed to the loss of connections in the left OTC

Nurses\u27 Alumnae Association Bulletin, June 1964

President\u27s Message Officers and Committee Chairmen Financial Report Hospital and School of Nursing Report Student Activities Jefferson Expansion Program Resume of Alumnae Meetings Staff Nurses Private Duty Social Committee Reports Program Scholarship Bulletin Committee Report Annual Luncheon Notes Membership and Dues Units in Jefferson Expansion Program Center Annual Giving Drive 1963 Report of Ways and Means Committee Jefferson Building Fund Contributions Annual Giving Contributions 1964 Jefferson Building Fund Report Help the Building Fund Committee! Vital Statistics Class News Notice

METHODS FOR APPLYING TRANSMISSION AND /eta/-vs-E CORRECTIONS IN THE DETERMINATION OF /eta/sub2200sub 2200 BY THE MACKLIN-deSAUSSURE EXPERIMENT

A careful determination of /sub 2200/ from results of the Macklin- deSaussure manganese-bath experiment involves corrections for (1) the weak but nonzero transmission of subcadmium neutrons through the uranium or plutonium foils and (2) the small variation of with energy in the subcadmium region. The derivation of a single general expression for applying both these corrections is presented, and two lBM 704 codes (MTC and GTC) which were written especially to facilitate the numerical evaluation of this combined correction factor are described. (auth

The Use of Antiepileptic Drugs (AEDs) for the Treatment of Pediatric Aggression and Mood Disorders

Aggressive symptomatology presents across multiple psychiatric, developmental, neurological and behavioral disorders, complicating the diagnosis and treatment of the underlying pathology. Anti-Epileptic Drugs (AEDs) have become an appealing alternative in the treatment of aggression, mood lability and impulsivity in adult and pediatric populations, although few controlled trials have explored their efficacy in treating pediatric populations. This review of the literature synthesizes the available data on ten AEDs—valproate, carbamazepine, oxcarbazepine, phenytoin, lamotrigine, topiramate, levetiracetam, zonisamide, gabapentin and tiagabine—in an attempt to assess evidence for the efficacy of AEDs in the treatment of aggression in pediatric populations. Our review revealed modest evidence that some of the AEDs produced improvement in pediatric aggression, but controlled trials in pediatric bipolar disorder have not been promising. Valproate is the best supported AED for aggression and should be considered as a first line of treatment. When monotherapy is insufficient, combining an AED with either lithium or an atypical anti-psychotic can result in better efficacy. Additionally, our review indicates that medications with predominately GABA-ergic mechanisms of action are not effective in treating aggression, and medications which decrease glutaminergic transmission tended to have more cognitive adverse effects. Agents with multiple mechanisms of action may be more effective