421 research outputs found
Time reversal symmetry in optics
The utilization of time reversal symmetry in designing and implementing
(quantum) optical experiments has become more and more frequent over the past
years. We review the basic idea underlying time reversal methods, illustrate it
with several examples and discuss a number of implications.Comment: 5 pages, 3 figures, typeset with revte
Placemaking in action: Factors that support or obstruct the development of urban community gardens
The paper examines factors that support or obstruct the development of urban community garden projects. It combines a systematic scholarly literature review with empirical research from case studies located in New Zealand and Germany. The findings are discussed against the backdrop of placemaking processes: urban community gardens are valuable platforms to observe space-to-place transformations. Following a social-constructionist approach, literature-informed enablers and barriers for the development of urban community gardens are analysed against perceived notions informed by local interviewees with regard to their biophysical and technical, socio-cultural and economic, and political and administrative dimensions. These dimensions are incorporated into a systematic and comprehensive category system. This approach helps observe how the essential biophysical-material base of the projects is overlaid with socio-cultural factors and shaped by governmental or administrative regulations. Perceptual differences become evident and are discussed through the lens of different actors
Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord
To obtain a thorough understanding of chronic pain, large-scale molecular mapping of the pain axis at the protein level is necessary, but has not yet been achieved. We applied quantitative proteome profiling to build a comprehensive protein compendium of three regions of the pain neuraxis in mice: the sciatic nerve (SN), the dorsal root ganglia (DRG), and the spinal cord (SC). Furthermore, extensive bioinformatics analysis enabled us to reveal unique protein subsets which are specifically enriched in the peripheral nervous system (PNS) and SC. The immense value of these datasets for the scientific community is highlighted by validation experiments, where we monitored protein network dynamics during neuropathic pain. Here, we resolved profound region-specific differences and distinct changes of PNS-enriched proteins under pathological conditions. Overall, we provide a unique and validated systems biology proteome resource (summarized in our online database painproteome.em.mpg.de), which facilitates mechanistic insights into somatosensory biology and chronic pain—a prerequisite for the identification of novel therapeutic targets
Diagnostic accuracy of CT angiography and CT perfusion imaging for detecting distal medium vessel occlusions: Protocol for a systematic review and meta-analysis
Background: Distal medium vessel occlusions (DMVOs) represent 25-40% of all acute ischemic strokes (AIS). DMVO clinical syndromes are heterogenous, but as eloquent brain regions are frequently involved, they are often disabling. Since current intravenous fibrinolytic therapies may fail to recanalize up to two-thirds of DMVOs, endovascular treatment is progressively being considered in this setting. Nevertheless, the optimal imaging method for diagnosis remains to be defined. Stroke centers that use computed tomography as a routine stroke imaging approach rely on either isolated computed tomography angiography (CTA) or combined perfusion (CTP) studies. Despite a simplified non-CTP-dependent approach seeming reasonable for large vessel occlusion AIS diagnosis, CTP may still hold advantages for DMVOs workup. Therefore, this systematic review aims to compare the diagnostic performance of CTA and CTP in detecting DMVOs.
Methods: We will perform a systematic search in PubMed, EMBASE, Web of Science Core Collection, and Cochrane Central Register of Controlled Trials. In addition, grey literature and ClinicalTrials.gov will be scanned. We will include any type of study that presents data on the diagnostic accuracy of CTA and/or CTP for detecting DMVOs. Two authors will independently review retrieved studies, and any discrepancies will be resolved by consensus or with a third reviewer. Reviewers will extract the data and assess the risk of bias in the selected studies. Data will be combined in a quantitative meta-analysis following the guidelines provided by the Cochrane Handbook for Systematic Reviews of Interventions. We will assess cumulative evidence using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
Discussion: This will be the first systematic review and meta-analysis that compares two different imaging approaches for detecting DMVOs. This study may help to define optimal acute ischemic stroke imaging work-up.
Trial registration: PROSPERO registration: CRD42022344006.info:eu-repo/semantics/publishedVersio
Unusual light spectra from a two-level atom in squeezed vacuum
We investigate the interaction of an atom with a multi-channel squeezed
vacuum. It turns out that the light coming out in a particular channel can have
anomalous spectral properties, among them asymmetry of the spectrum, absence of
the central peak as well as central hole burning for particular parameters. As
an example plane-wave squeezing is considered. In this case the above phenomena
can occur for the light spectra in certain directions. In the total spectrum
these phenomena are washed out.Comment: 16 pages, LaTeX, 3 figures (included via epsf
Influence of biological activity on 65Zn and 109Cd removal from tidal water by chronically-polluted mangrove sediments
The biological activity influence on the mangrove sediment capacity to remove 65Zn and 109Cd from tidal water was evaluated in a site chronically polluted. Benthic Activity Indexes (BAI), corresponding to relative estimates of biological impact on radiotracer accumulation, were higher for 109Cd (~ 38%) than for 65Zn (~ 10%) in the top centimetre of sediment. However, BAI exceeded 96% for deeper sediment layers. This apparent decrease in radiotracer diffusion into deep sediments through biological activity inhibition is stronger than reported for much less polluted mangrove nearby, suggesting that benthic organisms tolerant of chronic metal pollution may affect metal sorption mechanisms.info:eu-repo/semantics/publishedVersio
Stochastic wave function approach to the calculation of multitime correlation functions of open quantum systems
Within the framework of probability distributions on projective Hilbert space
a scheme for the calculation of multitime correlation functions is developed.
The starting point is the Markovian stochastic wave function description of an
open quantum system coupled to an environment consisting of an ensemble of
harmonic oscillators in arbitrary pure or mixed states. It is shown that matrix
elements of reduced Heisenberg picture operators and general time-ordered
correlation functions can be expressed by time-symmetric expectation values of
extended operators in a doubled Hilbert space. This representation allows the
construction of a stochastic process in the doubled Hilbert space which enables
the determination of arbitrary matrix elements and correlation functions. The
numerical efficiency of the resulting stochastic simulation algorithm is
investigated and compared with an alternative Monte Carlo wave function method
proposed first by Dalibard et al. [Phys. Rev. Lett. {\bf 68}, 580 (1992)]. By
means of a standard example the suggested algorithm is shown to be more
efficient numerically and to converge faster. Finally, some specific examples
from quantum optics are presented in order to illustrate the proposed method,
such as the coupling of a system to a vacuum, a squeezed vacuum within a finite
solid angle, and a thermal mixture of coherent states.Comment: RevTex, 19 pages, 3 figures, uses multico
Generation of a wave packet tailored to efficient free space excitation of a single atom
We demonstrate the generation of an optical dipole wave suitable for the
process of efficiently coupling single quanta of light and matter in free
space. We employ a parabolic mirror for the conversion of a transverse beam
mode to a focused dipole wave and show the required spatial and temporal
shaping of the mode incident onto the mirror. The results include a proof of
principle correction of the parabolic mirror's aberrations. For the application
of exciting an atom with a single photon pulse we demonstrate the creation of a
suitable temporal pulse envelope. We infer coupling strengths of 89% and
success probabilities of up to 87% for the application of exciting a single
atom for the current experimental parameters.Comment: to be published in Europ. Phys. J.
Heralded single photon absorption by a single atom
The emission and absorption of single photons by single atomic particles is a
fundamental limit of matter-light interaction, manifesting its quantum
mechanical nature. At the same time, as a controlled process it is a key
enabling tool for quantum technologies, such as quantum optical information
technology [1, 2] and quantum metrology [3, 4, 5, 6]. Controlling both emission
and absorption will allow implementing quantum networking scenarios [1, 7, 8,
9], where photonic communication of quantum information is interfaced with its
local processing in atoms. In studies of single-photon emission, recent
progress includes control of the shape, bandwidth, frequency, and polarization
of single-photon sources [10, 11, 12, 13, 14, 15, 16, 17], and the
demonstration of atom-photon entanglement [18, 19, 20]. Controlled absorption
of a single photon by a single atom is much less investigated; proposals exist
but only very preliminary steps have been taken experimentally such as
detecting the attenuation and phase shift of a weak laser beam by a single atom
[21, 22], and designing an optical system that covers a large fraction of the
full solid angle [23, 24, 25]. Here we report the interaction of single
heralded photons with a single trapped atom. We find strong correlations of the
detection of a heralding photon with a change in the quantum state of the atom
marking absorption of the quantum-correlated heralded photon. In coupling a
single absorber with a quantum light source, our experiment demonstrates
previously unexplored matter-light interaction, while opening up new avenues
towards photon-atom entanglement conversion in quantum technology.Comment: 10 pages, 4 figure
Mathematical utility theory and the representability of demand by continuous homogeneous functions
The resort to utility-theoretical issues will permit us to propose a constructive procedure for deriving a homogeneous of degree one continuous function that gives raise to a primitive demand function under suitably mild conditions. This constitutes the first self-contained and elementary proof of a necessary and sufficient condition for an integrability problem to have a solution by continuous (subjective utility) functions.info:eu-repo/semantics/publishedVersio
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