1,062 research outputs found

    Selection of a Realistic Viscous Vortex Tangential Velocity Profile for Computer Simulation of Vortex-Structure Interaction

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    Structure loading by vortices is a relevant phenomenon in numerous fields of engineering significance. Computer modelling is a powerful tool that can be used to study the loading produced on structures by impacting vortices. Realistic simulation of vortex-loading of structures necessitates the use of a realistic vortex tangential velocity profile (TVP). The present study compiles measured TVPs from various types of experimentally-produced vortices as well as real-world tornado and hurricane vortices. The measured TVPs are compared with commonly-used, analytical TVPs. Analytical TVPs that realistically represent the range of measured TVPs are identified and selected for use in future computer simulation studies

    Oxalate-Induced and Cell-Cycle-Dependent Expression of Nuclear Pore Complex Oxalate Binding Protein gp210

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    The effect of oxalate, a constituent of renal stone, on the expression of nuclear pore complex oxalate binding protein (gp210) in Vero monkey kidney cells was examined. The expression of this protein was found to increase more in mitotic phase than in S phase, suggesting cell cycle dependency. Exposure of cells to oxalate-containing growth medium resulted in a relative increase in nuclear pore complex oxalate binding protein in each stage of cell cycle. The concentration of this protein was found to increase six times in the telophase stage of the cells exposed to high concentrations of oxalate in the growth medium, though slight reduction in cell density was observed. Structural analogues of oxalate did not show any stimulatory effect on expression of this oxalate binding protein. Hence, the expression of the nuclear pore complex oxalate binding protein gp210 was specific to oxalate and is cell cycle dependent

    An Dynamic Voltage Regulator For HVDC System On Low Power DC Line With Series Active Power Filter And Reducing Repulsion To The Transmitting Station

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    Harmonics in HVDC power systems, which are caused by highly non-linear devices, affect its performance. Therefore, the main concern of power engineers in power system design and operation have been controlling and eliminating such repulsion. In respect of this, HVDC power system repulsion analysis is, therefore, imperative in power system planning, control and operation. It is worthy of note that, different alternatives of filter design should be considered before making final decision on filter Configuration. In this paper the reduction of harmonics in the HVDC power transmission system by implementing the active power filter. Also the power factor is increased drastically by reducing the current harmonics in the load side. The solar PV output can be presented and analyzed with help of boost converter in order to proof that the solar output voltage can be increased by the boost converter. The series active power filter appears to be a viable solution for eliminating repulsion currents and current transient condition. Shunt active power filter compensates current by injecting equal voltage compensation is created by nonlinear loads

    Long Term use of Cell Phone in Business Community causing Hearing Loss

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    INTRODUCTION: As civilization has progressed, the noise in man‘s environment has increased. The adverse effect of noise is widespread with respect to human physiology and produce changes in many bio systems other than ear. It is however the ear which concerns us here. Noise has been shown to have many effects on people such as, decrease in working efficiency, annoyance, physiological changes in blood pressure and heart rate and psychological distress. The direct auditory effects are interference with speech communication, produced due to the masking background noise, and the primary auditory effect, the capacity of noise to produce hearing loss. AIM OF THE STUDY: Noise induced hearing loss is a preventable hearing disorder. It affects people of all ages and demographic. When increased intensity is transmitted into and through the auditory system noise induced hearing loss results. MATERIALS AND METHODOLOGY: Cross sectional study. N=90, Age group: 18-50 years. Year of study: 2010-2012. Inclusion criteria: 1. 18 – 50 years of age, 2. Healthy male vegetable traders, 3. Any type of mobile phones, 4. Normal intact tympanic membrane. Exclusion criteria: 1. Any history of any other co morbid illness like hypertension, diabetes mellitus, cardiac illness. 2. Any ear disease which have hearing loss 3. Any surgery to the ear with no improvement of hearing after surgery. 4. Any intake of ototoxic medications. SUMMARY: The cross sectional study was conducted from a period of November 2010 to October 2012, to study the effects of cellphone usage over the human auditory system. Total number of subjects – 90 healthy males. All the subjects were in the age group of 18 to 50 years. 37.78% (34 / 90) of subjects had ear warmth. 34.44% (31 / 90) of subjects had ear fullness. 8.88% (8 / 90) of subjects had tinnitus. Pure tone audiometry done periodically at the interval of one year from the baseline audiogram showing threshold changes in one or two frequencies in the follow up audiogram in 10% of the subjects. These candidates must be followed up regularly, for a long term to derive a final conclusion. CONCLUSION: In this study, on following up of 90 candidates for 3 years with pure tone audiometry, no significant hearing loss was observed, except some threshold changes in one or two frequencies in the final follow up audiogram. It is also observed, that the ear symptoms like ear warmth and ear fullness was observed in approximately 30% of subjects and there was no relation between the ear symptoms and threshold changes. Mild cochlear changes can be revealed in Distortion product otoacoustic emissions and auditory brainstem response. However this is a small cross sectional study, a large sample and long term follow up will be required to derive definite conclusions

    Computer Modeling of Tornado Forces on a Cubic Building Using Large Eddy Simulation

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    A tornado changes its wind speed and direction rapidly; therefore, it is difficult to study the effects of a tornado on buildings in a wind tunnel. The status of the tornado-structure interaction and various models of the tornado wind field found in literature are surveyed. Three dimensional computer modeling work using the turbulence model based on large eddy simulation is presented. The effect of a tornado on a cubic building is considered for this study. The Navier-Stokes (NS) equations are approximated by the finite difference method and solved by an implicit procedure. The force coefficients are plotted in time to study the effect of Rankine combined vortex model. The tornado is made to translate at a 0° and 45° angle, and the grid resolution is refined. Some flow visualizations are also reported to enhance understanding of the flow behavior around the cube

    BIOCHEMICAL EVALUATION OF ANTIDIABETIC PROPERTIES OF SWERTIAMARIN, A SECOIRIDOID GLYCOSIDE OF ENICOSTEMMA LITTORALE LEAVES, STUDIED IN HIGH-FAT DIET–FED LOW-DOSE STREPTOZOTOCIN-INDUCED TYPE 2 DIABETIC RATS

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    Objective: Swertiamarin, a secoiridoid glycoside present in the leaves of Enicostemma littorale, is reported to be responsible for its pharmacological and beneficial properties. The present study was aimed to biochemically evaluate the antidiabetic properties of Swertiamarin in high fat diet fed - low dose streptozotocin (STZ)-treated diabetic rats.Methods: High-fat diet-fed low-dose STZ was used to induce experimental type 2 diabetes in rats. Diabetic rats were orally treated with swertiamarin (50 mg/kg b.w./rat/day) for 30 days. The physiological criterions such as food and fluid intake were recorded. Oral glucose tolerance test was performed. The levels of fasting blood glucose, plasma insulin, glycosylated hemoglobin A1c (HbA1c), hemoglobin, and homeostasis model assessment of insulin resistance (HOMA-IR) values were estimated. The activities of key enzymes involved in carbohydrate and glycogen metabolism in the liver and kidney tissues were assayed. The glycogen content in liver tissue was estimated.Result: Oral administration of swertiamarin to diabetic rats established a significant decline in the levels of fasting blood glucose, HbA1c as well as HOMA-IR values and an increase in plasma insulin and hemoglobin levels. The altered activities of key enzymes of carbohydrate and glycogen metabolism in liver and kidney tissues of diabetic rats were restored to near normalcy by swertiamarin treatment.Conclusion: Swertiamarin treatment maintains normoglycemia in diabetic rats by modulating the activities of key carbohydrate and glycogen metabolizing enzymes in the hepatic and renal tissues

    Static Stability and Dynamic Analysis of Barge Foaters for An Offshore Wind Turbine

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    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

    Adverse Drug Reaction Monitoring of Anticancer Drugs in Hematology Department

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    Background: Cancer is among the leading causes of mortality in India. Studies have reported antineoplastic agents as the common class of drugs causing Adverse Drug Reactions (ADRs). The present study aimed to conduct active surveillance of ADRs of anticancer drugs in the hematology department.Methods: A prospective observational study was conducted in 136 patients with cancer and the incidence and frequency of ADRs were assessed. The study was conducted in 6 months in a multispecialty hospital.Results: Among 136 cancer patients, All was more prevalent (39.70%); CLL, Non- Hodgkin’s Lymphoma were less prevalent (0.73%). ADRs were more prevalent in the Pediatrics department, i.e., 18.53% of ADRs were observed in patients aged <10 years. ADRs in male patients constituted 54.39%, whereas it was 45.60% in female patients. Cytarabine caused the highest number of ADRs (34.48%). The most prevalent ADR was anemia (25.60%).Conclusion: Multiple ADRs were detected in cancer patients. We found that hematological ADRs were more prevalent. Most of the ADRs were possible reactions according to Naranjo and the World Health Organization (WHO) scales

    Stability of Modified Host-Parasitoid Model with Allee Effect

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    This paper deals with a host-parasitoid model subject to Allee effect and its dynamical behavior. Steady state points of the proposed host-parasitoid model are computed. Stability properties are analyzed with eigen values of Jacobian matrix which are determined at the steady states. Theoretical findings are supported by numerical illustrations and enhanced by pictorial representations such as bifurcation diagrams, phase portraits and local amplifications for different parameter values. Existence of chaotic behavior in the system is established via bifurcation and sensitivity analysis of the system at the initial conditions. Various phase portraits are simulated for a better understanding of the qualitative behavior of the considered model

    Extrapolation of post-harvest soil test values in barnyard millet-based cropping sequence through multivariate analysis

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    The soil test value is based on the soil test-based fertilizer prescription/ recommendation equation. Each crop harvesting after the next crop is necessary to analyze the soil. Therefore, it is necessary to develop an alternative technique to predict postharvest soil tests after the harvest of every crop. For that a study was conducted in mixed black calcareous soils at Tamil Nadu agricultural University, Coimbatore to develop the post-harvest prediction equations for available nitrogen, phosphorus and potassium in barnyard millet cropping sequence based on a multiple regression model by considering post-harvest soil test value as the dependent variable and initial available nutrients, fertilizer doses and crop yield or crop nutrient uptake as an independent variables. The developed model was validated by computing R2 value, RMSE (root means square error), RE (relative error), and the ratio of performance to deviation (RPD) and the developed model was found to be valid.  Using the validated model, post-harvest soil test values were predicted. A fertilizer recommendation was made for blackgram based on predicted post-harvest soil test values in the barnyard millet-blackgram cropping sequence. The predicted soil test values were compared with actual soil test values and it revealed that the developed model is fairly accurate and best-fitted with more precision. The predicted post-harvest soil test values of barnyard millet could be used in order to prescribe fertilizer for desired yield targets for subsequent crops
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