153 research outputs found
Relocation and investment in R&D by firms
The literature on foreign direct investment has analyzed corporate location decisions when firms invest in R&D to reduce production costs. Such firms may set up new plants in other developed countries while maintaining their domestic plants. In contrast, we here consider firms that close down their domestic operations and relocate to countries where wage costs are lower. Thus, we assume that firms may reduce their production costs by investing in R&D and likewise by moving their plants abroad. We show that these two mechanisms are complementary. When a firm relocates it invests more in R&D than when it does not change its location and, therefore, its production cost is lower in the first case. As a result, investment in R&D encourages firms to relocate.info:eu-repo/semantics/publishedVersio
Green Criminology Before âGreen Criminologyâ: Amnesia and Absences
Although the first published use of the term âgreen criminologyâ seems to have been made by Lynch (Green criminology. Aldershot, Hampshire, 1990/2006), elements of the analysis and critique represented by the term were established well before this date. There is much criminological engagement with, and analysis of, environmental crime and harm that occurred prior to 1990 that deserves acknowledgement. In this article, we try to illuminate some of the antecedents of green criminology. Proceeding in this way allows us to learn from âabsencesâ, i.e. knowledge that existed but has been forgotten. We conclude by referring to green criminology not as an exclusionary label or barrier but as a symbol that guides and inspires the direction of research
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure information
Background :
Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio case but also when homology information to known structures is available. Structural properties are also routinely used in protein analysis even when homology is available, largely because homology modelling is lower throughput than, say, secondary structure prediction. Nonetheless, predictors of secondary structure and solvent accessibility are virtually always ab initio.
Results:
Here we develop high-throughput machine learning systems for the prediction of protein secondary structure and solvent accessibility that exploit homology to proteins of known structure, where available, in the form of simple structural frequency profiles extracted from sets of PDB templates. We compare these systems to their state-of-the-art ab initio counterparts, and with a number of baselines in which secondary structures and solvent accessibilities are extracted directly from the templates. We show that structural information from templates greatly improves secondary structure and solvent accessibility prediction quality, and that, on average, the systems significantly enrich the information contained in the templates. For sequence similarity exceeding 30%, secondary structure prediction quality is approximately 90%, close to its theoretical maximum, and 2-class solvent accessibility roughly 85%. Gains are robust with respect to template selection noise, and significant for marginal sequence similarity and for short alignments, supporting the claim that these improved predictions may prove beneficial beyond the case in which clear homology is available.
Conclusion:
The predictive system are publicly available at the address http://distill.ucd.ieScience Foundation IrelandIrish Research Council for Science, Engineering and TechnologyHealth Research BoardUCD President's Award 2004au, da, ke, ab, sp - kpw30/11/1
Lâaccompagnement-citoyen en soutien Ă la participation sociale des aĂźnĂ©s ayant un traumatisme craniocĂ©rĂ©bral
Hautement valorisée par les aßnés, la participation sociale a des effets bénéfiques sur leur
santĂ© biopsychosociale. Tous nâont pas cependant les mĂȘmes opportunitĂ©s pour sâinvestir
dans ce type dâactivitĂ©s; particuliĂšrement ceux ayant un traumatisme craniocĂ©rĂ©bral (TCC)
qui sont plus susceptibles dâĂȘtre limitĂ©s dans leurs capacitĂ©s Ă participer Ă la vie de la
communauté. Les initiatives les plus courantes pour aider ces personnes consistent en une
assistance humaine visant à pallierleurs limitations et ne misent pas, en priorité, sur la
promotion de leurs compĂ©tences. Afin dâoptimiser lâaide reçue, un accompagnementcitoyen
personnalisĂ© Ă lâintĂ©gration communautaire (APIC) a Ă©tĂ© dĂ©veloppĂ©, implantĂ© et
Ă©valuĂ©. Cet article documente lâimpact de lâAPIC sur la participation sociale dâaĂźnĂ©s ayant
un TCC. Une analyse de contenu thĂ©matique a Ă©tĂ© rĂ©alisĂ©e sur les donnĂ©es issues dâentrevues
semi-dirigées auprÚs des participants et des journaux de bord des accompagnateurs.
Les rĂ©sultats montrent trois grandes retombĂ©es de lâAPIC : une meilleure assurance et un
plus grand sentiment dâautonomie, un goĂ»t retrouvĂ© de sâinvestir dans des activitĂ©s de
loisirs signifiantes, et une plus grande ouverture vers de nouvelles possibilités de relations.Abstract : Highly valued by seniors, community integration has beneficial effects on their biopsychosocial
health. However, not all of them have the same opportunities to engage in
social participation activities, particularly those with traumatic brain injury (TBI) who are
more likely to be limited in their abilities to participate in the life of the community. The
most common initiatives to help these people consist of human assistance to overcome
their limitations and which do not focus on skills promotion. In order to optimize the
available services and resources, personalized citizen assistance for community integration
(APIC) has been developed, implemented, and evaluated. This article documents the
impact of APIC on the community integration of seniors with TBI. A thematic content
analysis was conducted on data from semi-structured interviews with participants and
from attendant logbooks. The results show three major spin-offs from APIC: better
insurance and a greater sense of autonomy, a renewed taste for investing in meaningful
leisure activities, and greater openness to new relationship opportunities
Constitution de l'univers relationnel dans ses rapports avec les premiers apprentissages d'aprĂšs
Mucchielli R. Constitution de l'univers relationnel dans ses rapports avec les premiers apprentissages d'aprÚs. In: RepÚres pour la rénovation de l'enseignement du français à l'école élémentaire, n°12, 1971. pp. 72-76
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