Impact of advanced inverter functions on low-voltage power grids

In today's power grid, a great number of inverter-based distributed energy resources (DERs) are connected and are mainly designed to supply power without considering the voltage and frequency deviations of the grid. Therefore, distribution system operators (DSOs) are challenged with an increase in grid events because of the random implementation of DERs. Voltage levels can vary beyond predefined limits at the point of connection and are currently not evaluated by DSOs. Summarized here is the development of a simulation model for evaluating the impact of support functions integrated in inverter-based DERs. The model aims to help grid operators simulate voltage and frequency events and study the impact of DERs to the grid with respect to different settings of integrated support functions. A model is developed in MATLAB/Simulink conforming to European standards and regulations. Grid dynamics can be evaluated by imitating voltage and frequency deviations. Support functions can be either adjusted according to the situation or turned off. Together with adjustable settings according to DSO request, this model offers flexibility and insight in the capabilities of DERs to solve voltage and frequency issues. Case studies show that the model corresponds to expected behaviour and can be used for further development

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32)

The BCR-ABL1 fusion kinase is frequently associated with chronic myeloid leukemia and B-cell acute lymphoblastic leukemia but is rare in T-cell acute lymphoblastic leukemia (T-ALL). We recently identified NUP214-ABL1 as a variant ABL1 fusion gene in 6% of T-ALL patients. Here we describe the identification of another ABL1 fusion, EML1-ABL1, in a T-ALL patient with a cryptic t(9;14)(q34;q32) associated with deletion of CDKN2A (p16) and expression of TLX1 (HOX11). Echinoderm microtubule-associated protein-like 1-Abelson 1 (EML1-ABL1) is a constitutively phosphorylated tyrosine kinase that transforms Ba/F3 cells to growth factor-independent growth through activation of survival and proliferation pathways, including extracellular signal-related kinase 1/2 (Erk1/2), signal transducers and activators of transcription 5 (Stat5), and Lyn kinase. Deletion of the coiled-coil domain of EML1 abrogated the transforming properties of the fusion kinase. EML1-ABL1 and breakpoint cluster region (BCR)-ABL1 were equally sensitive to the tyrosine kinase inhibitor imatinib. These data further demonstrate the involvement of ABL1 fusions in the pathogenesis of T-ALL and identify EML1-ABL1 as a novel therapeutic target of imatinib

Safe Design Suggestions for Vegetated Roofs

Rooftop vegetation is becoming increasingly popular because of its environmental benefits and its ability to earn green-building certification credits. With the exception of one international guideline, there is little mention of worker safety and health in vegetated-roof codes and literature. Observations and field investigations of 19 vegetated roofs in the United States revealed unsafe access for workers and equipment, a lack of fall-protection measures, and other site-specific hazards. Design for safety strategies and the integration of life-cycle safety thinking with green-building credits systems are the preferred methods to reduce risk to workers on vegetated roofs. Design suggestions have been developed to add to the body of knowledge. The findings complement several National Institute for Occupational Safety and Health (NIOSH) construction and prevention through design (PtD) goals and are congruent with NIOSH’s Safe Green Jobs initiative. Organizations that install and maintain vegetated roofs can utilize the findings to understand hazards, take precautions, and incorporate safety into their bids The published version of this article is available here: 10.1061/(ASCE)CO.1943-7862.0000500Support from the the Virginia Tech Occupational Safety and Health Research Center through the Kevin P. Granata Pilot Program funded by the Institute for Critical Technology and Applied Sciences

Contesting longstanding conceptualisations of urban green space

Ever since the Victorian era saw the creation of “parks for the people,” health and wellbeing benefits have been considered a primary benefit of urban parks and green spaces. Today, public health remains a policy priority, with illnesses and conditions such as diabetes, obesity and depression a mounting concern, notably in increasingly urbanised environments. Urban green space often is portrayed as a nature-based solution for addressing such health concerns. In this chapter, Meredith Whitten investigates how the health and wellbeing benefits these spaces provide are limited by a narrow perspective of urban green space. Whitten explores how our understandings of urban green space remain rooted in Victorian ideals and calls into question how fit for purpose they are in twenty-first-century cities. Calling on empirical evidence collected in three boroughs in London with changing and increasing demographic populations, she challenges the long-held cultural underpinnings that lead to urban green space being portrayed “as a panacea to urban problems, yet treating it as a ‘cosmetic afterthought’” (Whitten, M, Reconceptualising green space: planning for urban green space in the contemporary city. Doctoral thesis, London School of Economics and Political Science, London, U.K. http://etheses.lse.ac.uk/. Accessed 12 Jun 2019, 2019b, p 18)

Biophilic architecture: a review of the rationale and outcomes

Contemporary cities have high stress levels, mental health issues, high crime levels and ill health, while the built environment shows increasing problems with urban heat island effects and air and water pollution. Emerging from these concerns is a new set of design principles and practices where nature needs to play a bigger part called “biophilic architecture”. This design approach asserts that humans have an innate connection with nature that can assist to make buildings and cities more effective human abodes. This paper examines the evidence for this innate human psychological and physiological link to nature and then assesses the emerging research supporting the multiple social, environmental and economic benefits of biophilic architecture

NimbleAI: towards neuromorphic sensing-processing 3D-integrated chips

Computer Systems, Imagery and Medi

Area-optimized montgomery multiplication on IGLOO 2 FPGAs

Contains fulltext : 178481.pdf (Publisher’s version ) (Open Access)FPL 2017: 27th International Conference on Field Programmable Logic and Applications (FPL) September 4-6, 2017 Gent, Belgiu