736 research outputs found
Transport and diffusion in the embedding map
We study the transport properties of passive inertial particles in a
incompressible flows. Here the particle dynamics is represented by the
dissipative embedding map of area-preserving standard map which models
the incompressible flow. The system is a model for impurity dynamics in a fluid
and is characterized by two parameters, the inertia parameter , and the
dissipation parameter . We obtain the statistical characterisers of
transport for this system in these dynamical regimes. These are, the recurrence
time statistics, the diffusion constant, and the distribution of jump lengths.
The recurrence time distribution shows a power law tail in the dynamical
regimes where there is preferential concentration of particles in sticky
regions of the phase space, and an exponential decay in mixing regimes. The
diffusion constant shows behaviour of three types - normal, subdiffusive and
superdiffusive, depending on the parameter regimes. Phase diagrams of the
system are constructed to differentiate different types of diffusion behaviour,
as well as the behaviour of the absolute drift. We correlate the dynamical
regimes seen for the system at different parameter values with the transport
properties observed at these regimes, and in the behaviour of the transients.
This system also shows the existence of a crisis and unstable dimension
variability at certain parameter values. The signature of the unstable
dimension variability is seen in the statistical characterisers of transport.
We discuss the implications of our results for realistic systems.Comment: 28 pages, 14 figures, To Appear in Phys. Rev. E; Vol. 79 (2009
An Ayurvedic approach to the management of Shushkakshipaka w.s.r. to Dry Eye Syndrome - A Case Report
Introduction: Sushkakshipaka is one among the Sarvagata, Sadhya Netrarogas described in in classical Ayurveda texts. A feature of Shushkakshipaka includes hard and dry eye lids, found drooping; blurred vision and difficulty to open the eyes with irritation and foreign body sensation. The Lakshanas of Shushkakshipaka can be equated with the signs and symptoms of Dry Eye Syndrome. Dry eye is a multifactorial ocular surface disease characterized by symptoms of discomfort, irritation, and visual disturbance. Here the patient presenting with signs and symptoms of dry eye disease was treated according to the treatment principles of Shushkakshipaka as explained in Ayurvedic classics. Erandamoola Kheera Seka and Shatavari Ghrita was selected for the treatment and the same has been presented in the article. Materials and Methods: The subject who approached Shalakya Tantra OPD of Sri Jayachamarajendra Institute of Indian Medicine Hospital, Bengaluru, with signs and symptoms of dry eye disease was thoroughly examined and systematically reviewed. Treatment was planned based on the Chikitsasutra of Shushkakshipaka. Result: The patient showed considerable improvement subjectively and objectively. Improvement in Schirmer’s reading, visual acuity improvement was observed in both eyes. Conclusion: The maintenance of stability of tear film is the main challenge in this pandemic time due to the increased screen time. This can be achieved up to an extend by proper administration of treatment techniques described in classical Ayurveda texts along with Pathyasevana
Exploratory advancement in the optimal utilization of bio-wastes for ZnO nanoparticle synthesis in antimicrobial applications
The wealth out of Waste (WoW) concept progressively developed for the industrial revolution in recent years. So, bio-waste mediated synthesis of nanoparticles has emerged as a promising approach, leveraging the unique properties of bio-wastes and agricultural wastes. In this study, extracts from Eggshell, Peanut husk, and Orange peels were used to synthesize zinc oxide nanoparticles. The structural, vibration, and morphological properties of the synthesized ZnO nanoparticles were investigated and reported. It reveals that the distinct vibration peaks with strong existence of Zn-O bands from FT-IR spectra. Overall, this study highlights the incomparable structural and morphological properties of bio-waste extracts and their impact on the synthesis and functionality of zinc oxide nanoparticles, paving the way for future research in antimicrobial and targeted drug delivery applications
Resource-Efficient Quantum Circuits for Molecular Simulations: A Case Study of Umbrella Inversion in Ammonia
We conducted a thorough evaluation of various state-of-the-art strategies to
prepare the ground state wavefunction of a system on a quantum computer,
specifically within the framework of variational quantum eigensolver (VQE).
Despite the advantages of VQE and its variants, the current quantum
computational chemistry calculations often provide inaccurate results for
larger molecules, mainly due to the polynomial growth in the depth of quantum
circuits and the number of two-qubit gates, such as CNOT gates. To alleviate
this problem, we aim to design efficient quantum circuits that would outperform
the existing ones on the current noisy quantum devices. In this study, we
designed a novel quantum circuit that reduces the required circuit depth and
number of two-qubit entangling gates by about 60%, while retaining the accuracy
of the ground state energies close to the chemical accuracy. Moreover, even in
the presence of device noise, these novel shallower circuits yielded
substantially low error rates than the existing approaches for predicting the
ground state energies of molecules. By considering the umbrella inversion
process in ammonia molecule as an example, we demonstrated the advantages of
this new approach and estimated the energy barrier for the inversion process.Comment: 7 pages, 8 figure
Compact Planar One-Shot Circular Spark Gap Switch
The fabrication and characterisation of micro spark gap switch for single shot firing applications are given in detailed . A circular switch with triggering electrode is realised on alumina substrate and can be integratable easily with the electronics for ignition applications. Circular switch is realised on 25 mil alumina substrate within substrate diameter of 10 mm. The switch measurement shows having repeatable performance of pulse peak current of around 2000 A and less than 100 ns rise time. This article details the design, development including fabrication aspects of spark switch with trigger capabilities along with characterisation of switch on alumina substrates.
Drug utilization study and prescribing patterns in psychiatry patients at a tertiary care hospital
Background: The Drug utilization research (DUR) compares drug use between different countries and regions and is used to assess the rationality of prescribing pattern of the drug therapy. With this background we decided to evaluate antipsychotic drugs prescribing pattern in the psychiatric patients in a tertiary care hospital.Methods:Â The study was carried out at Department of Psychiatry, DSMCH. It was open label, cross - sectional, prescribed Documents based study. Duration of the study was one month (May-2017). Out-Patient number, age, sex, diagnosis, prescribed generic name, brand name, dose, route of administration, duration of therapy obtained from the Prescription register of Out - Patient Department of the Psychiatry.Results: The clinical experiences of the Psychiatrist I, II and III were 17 years, 35 years and 10 years respectively. The Psychiatrist I, II and III prescribed treatment for 36 (31.9%), 61 (54%) and 16 (14.2%) patients respectively. Among overall (n=113) patients (average age 38.9 years), male n=56 (49.6%) and female=57 (50.4%) were treated by all the three psychiatrists. The percentage of prescription of various drugs used were: Escitalopram (15.7%), Clonazepam (14.6%), Sertraline (8.7%), Risperidone (7.5%), Propranolol (6.7%), Olanzapine (6.3%), Quetiapine (5.9%), Trihexyphenidyl (5.5%), Amitriptyline (5.1%) and Other prescribed drugs, were between (0.4 to 2.8%).Conclusions: From this study, it can conclude that rational usage of drugs were followed in this study. All three prescribers (Psychiatrist I, II, and III) prescriptions were found to be rationale
Multi-phonon Raman scattering in semiconductor nanocrystals: importance of non-adiabatic transitions
Multi-phonon Raman scattering in semiconductor nanocrystals is treated taking
into account both adiabatic and non-adiabatic phonon-assisted optical
transitions. Because phonons of various symmetries are involved in scattering
processes, there is a considerable enhancement of intensities of multi-phonon
peaks in nanocrystal Raman spectra. Cases of strong and weak band mixing are
considered in detail. In the first case, fundamental scattering takes place via
internal electron-hole states and is participated by s- and d-phonons, while in
the second case, when the intensity of the one-phonon Raman peak is strongly
influenced by the interaction of an electron and of a hole with interface
imperfections (e. g., with trapped charge), p-phonons are most active.
Calculations of Raman scattering spectra for CdSe and PbS nanocrystals give a
good quantitative agreement with recent experimental results.Comment: 16 pages, 2 figures, E-mail addresses: [email protected],
[email protected], [email protected], accepted for publication in
Physical Review
Plant microbiome-dependent immune enhancing action of Echinacea purpurea is enhanced by soil organic matter content
© 2019 The Authors Anthemis austriaca Jacq. flowers are traditionally used to alleviate abdominal pain, hemorrhoids, ovary diseases and pneumonia. This study aimed to investigate the effects of A. austriaca flowers, which are frequently used in gynecological disorders, on the rat endometriosis model. The rat endometriosis model was used to evaluate the potential activity of the plant in endometriosis. The dried plant material was extracted with n-hexane, ethyl acetate (EtOAc), and methanol (MeOH), successively. The obtained extracts from A. austriaca flowers were applied to the rats. The adhesion scores, endometrial foci areas, and cytokine levels of the peritoneal fluids were measured on surgical induction of endometriosis in rats. The adhesion scores, endometriotic volume, and cytokine levels of the peritoneal fluids were reduced in the EtOAc, MeOH, and buserelin acetate-treated (reference) groups. The MeOH extract reduced the adhesion scores and endometrial foci areas from 3.1 to 1.1 (p \u3c 0.01) and from 86.4 to 40.5 (p \u3c 0.01), respectively and also the MeOH extract reduced tumor necrosis factor (TNF)-α, vascular endothelial growth factor (VEGF), and interleukin (IL)-6 levels of the peritoneal fluids from 13.7 to 3.8 (p \u3c 0.01), from 28.4 to 16.3 (p \u3c 0.05) and from 50.2 to 24.3 (p \u3c 0.01), respectively. Therefore, isolation studies were conducted on the EtOAc and MeOH extracts. After the MeOH extract was fractionated using RP-18 column, the obtained subfractions were evaluated again on the endometriosis rat model. Subfractions A and C of the MeOH extract displayed statistically significant activity on the endometriosis rat model. Phytochemical investigation resulted in the isolation of 4-β-D-glucopyranosyloxy-6-methyl-2H-pyran-2-one (1) from Fr. A and quercetin (2), apigenin-7-O-(3″-O-acetyl)-β-D-glucopyranoside (3), apigenin-7-O-(6″-O-acetyl)-β-D-glucopyranoside (4), apigenin-7-O-β-D-glucopyranoside (5), quercetin-7-O-β-D-glucopyranoside (6) from Fr. C. Moreover, β-sitosterol-3-O-β-D-glucopyranoside (7) was isolated from the EtOAc extract. As a conclusion, the MeOH extract obtained from A. austriaca flowers contributed to the regression of endometriosis. In addition, flavonoids and sterols of the plant were detected as the possible compounds responsible for the activity
Photoluminescent diamond nanoparticles for cell labeling: study of the uptake mechanism in mammalian cells
Diamond nanoparticles (nanodiamonds) have been recently proposed as new
labels for cellular imaging. For small nanodiamonds (size <40 nm) resonant
laser scattering and Raman scattering cross-sections are too small to allow
single nanoparticle observation. Nanodiamonds can however be rendered
photoluminescent with a perfect photostability at room temperature. Such a
remarkable property allows easier single-particle tracking over long
time-scales. In this work we use photoluminescent nanodiamonds of size <50 nm
for intracellular labeling and investigate the mechanism of their uptake by
living cells . By blocking selectively different uptake processes we show that
nanodiamonds enter cells mainly by endocytosis and converging data indicate
that it is clathrin mediated. We also examine nanodiamonds intracellular
localization in endocytic vesicles using immunofluorescence and transmission
electron microscopy. We find a high degree of colocalization between vesicles
and the biggest nanoparticles or aggregates, while the smallest particles
appear free in the cytosol. Our results pave the way for the use of
photoluminescent nanodiamonds in targeted intracellular labeling or biomolecule
deliver
Unraveling trait relationships in maize inbred lines
An experiment was carried out during Kharif 2020 at wetland farm of Sri Venkateswara Agricultural College, Tirupati using 30 inbred lines of maize to assess the trait association for 16 yield and yield attributes. It revealed that ear length, number of kernels per row, plant height, ear girth, SPAD chlorophyll meter reading, 100 kernel weight, number of kernel rows per ear, specific leaf area, harvest index and tassel length had notable positive correlation with kernel yield per plant suggesting that selecting these characters simultaneously lead to an increase in kernel yield per plant. Path analysis revealed a significant and positive direct influence of ear length on the kernel yield per plant. Hence, ear length could be considered during selection in maize for improving kernel yield
- …