2-Ethyl-6-(2-pyrid­yl)-5,6,6a,11b-tetra­hydro-7H-indeno[2,1-c]quinoline

The title compound, C23H22N2, was obtained using the three-component imino Diels–Alder reaction via a one-pot condensation between anilines, α-pyridine­carboxy­aldehyde and indene using BF3·OEt2 as the catalyst. The mol­ecular structure reveals the cis-form as the unique diastereoisomer. The crystal structure comprises one-dimensional zigzag ribbons connected via N—H⋯N hydrogen bonds. C—H⋯π inter­actions also occur

Scavenger Activity Evaluation of the Clove Bud Essential Oil (Eugenia caryophyllus) and Eugenol Derivatives Employing ABTS+• Decolorization

The essential oil (EO) of clove bud dried fruits from Eugenia caryophyllus was obtained by a conventional hydrodistillation process in an excellent yield (11.7 %). Its chemical composition was analyzed by GC-MS, identifying eugenol as a main constituent (60.5%). Four eugenol-like molecules, γ-diisoeugenol, hydroxymethyleugenol, dihydroeugenol and 1,3-dioxanylphenol, were synthesized using eugenol or isoeugenol as initial precursors under green chemistry protocols. To evaluate the possible antioxidant capacity of eugenol compounds including the clove bud EO, the Trolox® Equivalent Antioxidant Capacity value, obtained by the ABTS+• radical-cation discoloration method, was employed. The methodology was performed in a UV-Vis reader of 96-well microplates (dilution methodology), using well-known antioxidant agents (BHA, BHT and vitamin E) as reference compounds. It was found that the prepared eugenol derivatives had a more potent free radical scavenger activity than the reference compounds. In particular, the most active molecules, γ-diisoeugenol and 1,3-dioxanylphenol, were ca. 3-fold more potent than vitamin E

Half-Periodic Josephson Effect in an s-Wave Superconductor - Normal Metal -d-Wave Superconductor Junction

We predict that the Josephson current in a clean s-wave superconductor-normal metal-d-wave superconductor junction is periodic in superconducting phase difference $\phi$ with period $\pi$ instead of $2\pi$. The frequency of non-stationary Josephson effect is correspondingly $2\omega_J = 4eV.$ The effect is due to coexistence in the normal layer of current carrying Andreev levels with phase differences $\phi$ and $\phi+\pi.$Comment: 4 pages, REVTeX, 3 figure

Time reversal symmetry breaking superconductivity

We study time reversal symmetry breaking superconductivity with $\Delta_k = \Delta_{x^2-y^2} (k) +e^{i\theta} \Delta_{\alpha}$ ($\alpha = s$ or $d_{xy}$) symmetries. It is shown that the behavior of such superconductors could be {\em qualitatively} different depending on the minor components ($\alpha$) and its phase at lower temperatures. It is argued that such {\em qualitatively different} behaviors in thermal as well as in angular dependencies could be a {\em source} of consequences in transport and Josephson physics. Orthorhombicity is found to be a strong mechanism for mixed phase (in case of $\alpha = s$). We show that due to electron correlation the order parameter is more like a pure $d_{x^2-y^2}$ symmetry near optimum doping.Comment: 5 pages, 5 figures (attached), to be published in Physical Review

Precise Measurement of Sigma Beam Asymmetry for Positive Pion Photoproduction on the Proton from 800 to 1500 Mev

The Sigma beam asymmetry for positive pion photoproduction on the proton has been measured over an angular range of 40-170 deg at photon energies from 0.8 to 1.5 GeV. The resulting data set includes 237 accurate points, 136 of these belonging to an almost unexplored domain above 1.05 GeV. Data of such high precision provide severe constraints for partial wave analyses. The influence of this experiment on the GW multipole analysis is demonstrated. Significant changes are found in multipoles connected to the S31(1620) and P13(1720) resonances. Comparisons using the MAID analysis are also presented.Comment: 11 pages, 4 eps figures. to be published in Physics Letters

A bottom-up emission estimate for the 2022 Nord Stream gas leak: derivation, simulations, and evaluation

A major release of methane from the Nord Stream pipelines occurred in the Baltic Sea on 26 September 2022. Elevated levels of methane were recorded at many observational sites in northern Europe. While it is relatively straightforward to estimate the total emitted amount from the incidents (around 330 kt of methane), the detailed vertical and temporal distributions of the releases are needed for numerical simulations of the incident. Based on information from public media and basic physical concepts, we reconstructed vertical profiles and temporal evolution of the methane releases from the broken pipes and simulated subsequent transport of the released methane in the atmosphere. The parameterization for the initial rise of the buoyant methane plume has been validated with a set of large-eddy simulations by means of the UCLALES model. The estimated emission source was used to simulate the dispersion of the gas plume with the SILAM chemistry transport model. The simulated fields of the excess methane led to a noticeable increase in concentrations at several carbon-monitoring stations in the Baltic Sea region. Comparison of the simulated and observed time series indicated an agreement within a couple of hours between the timing of the plume arrival/departure at the stations with observed methane peaks. Comparison of absolute levels was quite uncertain. At most of the stations the magnitude of the observed and modeled peaks was comparable with the natural variability of methane concentrations. The magnitude of peaks at a few stations close to the release was well above natural variability; however, the magnitude of the peaks was very sensitive to minor uncertainties in the emission vertical profile and in the meteorology used to drive SILAM. The obtained emission inventory and the simulation results can be used for further analysis of the incident and its climate impact. They can also be used as a test case for atmospheric dispersion models.</p

Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera: Noctuidae) larvae infesting maize in Colombia

The anti-acetylcholinesterase, larvicidal, antifeedant activities and general toxicity of 15 semisynthetic eugenol derivatives based on clove oil (including the own oil), were evaluated against the maize armyworm, Spodoptera frugiperda (J.E. Smith). Therefore, promising eugenol molecules were classified with larvicidal, anti-acetylcholinesterase and antifeedant activities for controlling this pest. During structure–activity relationship studies and physicochemical profile analysis, it was found that among tested molecules 1-15, eugenol 1, prenyl eugenol 4, isoeugenol 8 and isoeugenol acetate 11 exhibited lethal effects LD50 at concentrations < 1 mg/g of insect. On the other hand, eugenol 1, metallyl eugenol 3, isoeugenol 8 and isoeugenol acetate 11 showed a good antifeedant activity (CE50 =158-209 µg/mL) with a high antifeedant index (70-78 %) at concentration 1000 µg/mL, possessing a weak antiacetylcholinesterase activity (IC50 = 21-31 g/mL). According to their ecotoxicological profiles (LC50 = 2033.1-6303.8 µg/mL on Artemia salina larvae), isoeugenol 8 and its acetate derivative 11 could be potential used in control of the growth, feeding, or reproduction of S. frugiperda larvae, acting as moderate insecticidal acetylcholinesterase inhibitors and/or antifeedant molecules. Such structure–activity relationship studies could stimulate the identification of lead structures from natural sources for the development of larvicidal and deterrent products against S. frugiperda and related insect pests.Fil: Vargas Méndez, Leonor Y.. Universidad Santo Tomás; ColombiaFil: Sanabria Flórez, Pedro L.. Universidad Santo Tomás; ColombiaFil: Saavedra Reyes, Laura Marcela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Santo Tomás; ColombiaFil: Merchan Arenas, Diego R.. Universidad Industrial Santander; ColombiaFil: Kouznetsov, Vladimir V.. Universidad Industrial Santander; Colombi

Josephson scanning tunneling microscopy

We propose a set of scanning tunneling microscopy experiments in which the surface of superconductor is scanned by a superconducting tip. Potential capabilities of such experimental setup are discussed. Most important anticipated results of such an experiment include the position-resolved measurement of the superconducting order parameter and the possibility to determine the nature of the secondary component of the order parameter at the surface. The theoretical description based on the tunneling Hamiltonian formalism is presented.Comment: 6 pages, 7 figures, submitted to Phys. Rev.

Uncertainty of eddy covariance flux measurements over an urban area based on two towers

The eddy covariance (EC) technique is the most direct method for measuring the exchange between the surface and the atmosphere in different ecosystems. Thus, it is commonly used to get information on air pollutant and greenhouse gas emissions, and on turbulent heat transfer. Typically an ecosystem is monitored by only one single EC measurement station at a time, making the ecosystem-level flux values subject to random and systematic uncertainties. Furthermore, in urban ecosystems we often have no choice but to conduct the single-point measurements in non-ideal locations such as close to buildings and/or in the roughness sub-layer, bringing further complications to data analysis and flux estimations. In order to tackle the question of how representative a single EC measurement point in an urban area can be, two identical EC systems - measuring momentum, sensible and latent heat, and carbon dioxide fluxes - were installed on each side of the same building structure in central Helsinki, Finland, during July 2013-September 2015. The main interests were to understand the sensitivity of the vertical fluxes on the single measurement point and to estimate the systematic uncertainty in annual cumulative values due to missing data if certain, relatively wide, flow-distorted wind sectors are disregarded. The momentum and measured scalar fluxes respond very differently to the distortion caused by the building structure. The momentum flux is the most sensitive to the measurement location, whereas scalar fluxes are less impacted. The flow distortion areas of the two EC systems (40-150 and 230-340 degrees) are best detected from the mean-wind-normalised turbulent kinetic energy, and outside these areas the median relative random uncertainties of the studied fluxes measured by one system are between 12 % and 28 %. Different gap-filling methods with which to yield annual cumulative fluxes show how using data from a single EC measurement point can cause up to a 12 % (480 g C m(-2)) underestimation in the cumulative carbon fluxes as compared to combined data from the two systems. Combining the data from two EC systems also increases the fraction of usable half-hourly carbon fluxes from 45 % to 69 % at the annual level. For sensible and latent heat, the respective underestimations are up to 5 % and 8 % (0.094 and 0.069 TJ m(-2)). The obtained random and systematic uncertainties are in the same range as observed in vegetated ecosystems. We also show how the commonly used data flagging criteria in natural ecosystems, kurtosis and skewness, are not necessarily suitable for filtering out data in a densely built urban environment. The results show how the single measurement system can be used to derive representative flux values for central Helsinki, but the addition of second system to other side of the building structure decreases the systematic uncertainties. Comparable results can be expected in similarly dense city locations where no large directional deviations in the source area are seen. In general, the obtained results will aid the scientific community by providing information about the sensitivity of EC measurements and their quality flagging in urban areas.Peer reviewe