Endometriosis: A Rare Cause of Large Bowel Obstruction.

Large bowel obstruction can result in significant morbidity and mortality, especially in cases of acute complete obstruction. There are many possible causes, the most common in adults being colorectal cancer. Endometriosis is a benign disease, and the most affected extragenital location is the bowel, especially the rectosigmoid junction. However, transmural involvement and acute occlusion are very rare events. We report an exceptional case of acute large bowel obstruction as the initial presentation of endometriosis. The differential diagnosis of colorectal carcinoma may be challenging, and this case emphasizes the need to consider intestinal endometriosis in females at a fertile age presenting with gastrointestinal symptoms and an intestinal mass causing complete large bowel obstruction.info:eu-repo/semantics/publishedVersio

Complexity-Aware Assignment of Latent Values in Discriminative Models for Accurate Gesture Recognition

Many of the state-of-the-art algorithms for gesture recognition are based on Conditional Random Fields (CRFs). Successful approaches, such as the Latent-Dynamic CRFs, extend the CRF by incorporating latent variables, whose values are mapped to the values of the labels. In this paper we propose a novel methodology to set the latent values according to the gesture complexity. We use an heuristic that iterates through the samples associated with each label value, stimating their complexity. We then use it to assign the latent values to the label values. We evaluate our method on the task of recognizing human gestures from video streams. The experiments were performed in binary datasets, generated by grouping different labels. Our results demonstrate that our approach outperforms the arbitrary one in many cases, increasing the accuracy by up to 10%.Comment: Conference paper published at 2016 29th SIBGRAPI, Conference on Graphics, Patterns and Images (SIBGRAPI). 8 pages, 7 figure

A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations

The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a form of symptomatic cholelithiasis occurring in young adults, characterized by recurrence of symptoms after cholecystectomy and presence of hepatolithiasis. The case refers to a healthy 39-year-old Caucasian male who presented with abdominal pain and jaundice. His blood tests showed conjugated hyperbilirubinemia and elevated liver enzymes (total bilirubin 6.65 mg/dL, γ-glutamyltransferase 699 IU/L) and abdominal computed tomography revealed dilation of common bile duct and left intrahepatic ducts. Magnetic resonance cholangiopancreatography identified choledocholithiasis, retrieved by endoscopic retrograde cholangiopancreatography, after which there was a worsening of jaundice (total bilirubin 23 mg/dL), which persisted for several weeks, possibly due to ciprofloxacin toxicity. After an extensive workup including liver biopsy, the identification of two foci of hepatolithiasis on reevaluation abdominal ultrasound raised the hypothesis of LPAC syndrome and the patient was started on ursodeoxycholic acid, with remarkable improvement. Genetic testing identified the mutation c.1954A>G (p.Arg652Gly) in ABCB4 gene (homozygous) and c.1331T>C (p.Val444Ala) in ABCB11 gene (heterozygous). In conclusion, we describe the unique case of an adult male with choledocholithiasis, hepatolithiasis, and persistent conjugated hyperbilirubinemia after retrieval of stones, fulfilling the criteria for LPAC syndrome and with possible superimposed drug-induced liver injury, in whom ABCB4 and ABCB11 mutations were found, both of which had not been previously described in association with LPAC.info:eu-repo/semantics/publishedVersio

Seasonal and depth-driven changes in rhodolith bed structure and associated macroalgae off Arvoredo island (southeastern Brazil)

Rhodoliths are formed by coralline red algae and can form heterogeneous substrata with high biodiversity. Here we describe a rhodolith bed at the southern limit of the known distribution of this habitat in the western Atlantic. We characterized rhodolith and macroalgal assemblages at 5, 10 and 15. m depth during summer and winter. Lithothamnion crispatum was dominant amongst the six rhodolith-forming species present. Most rhodoliths were spheroidal in shape indicating high mobility due to water movement. Rhodolith density decreased with increasing depth and during winter. Turf-forming seaweeds accounted for 60% of the biomass growing on rhodoliths. Macroalgae increased abundance and richness in the summer, but was similar between 5 and 15. m depth. They were less abundant and diverse than that recorded in rhodolith beds further north in Brazil. Both, season and depth, affected the structure of the macroalgae assemblages. We conclude that Lithothamniom is the most representative genus of Brazilian rhodolith beds. Summer is responsible for increasing the diversity and richness of macroalgae, as well as increasing rhodolith density. © 2013 Elsevier B.V

Fat area and lipid droplet morphology of porcine oocytes during in vitro maturation with trans-10, cis-12 conjugated linoleic acid and forskolin

Lipid droplets (LD) in porcine oocytes form a dark mass reaching almost all cytoplasm. Herein we investigated changes in fat areas, cytoplasmic tone and LD morphology during in vitro maturation (IVM) of porcine oocytes cultured with 100mM trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) or 10mM forskolin at different time periods. Four groups were constituted: control, excipient, t10,c12 CLA and forskolin, with drugs being supplemented during 44 to 48h and the initial 22 to 24h in Experiments 1 and 2, respectively. In Experiment 3, forskolin was supplemented for the first 2 h. Matured oocytes were inseminated with frozen-thawed boar semen and cleavage rate recorded. Before and during IVM, samples of oocytes were evaluated for LD, total and fat areas and fat gray value or for meiotic progression. Results showed that forskolin supplementation during 44 to 48 h or 22 to 24 h inhibits oocyte maturation (exp. 1: forskolin = 5.1±8.0%, control = 72.6±5.0%; exp. 2: forskolin =24.3±7.4%, control =71.6±5.6%) and cleavage (exp. 1: forskolin=0.0±0.0%, control=55.4±4.1%; exp. 2: forskolin=8.3±3.3%, control=54.5±3.0%). Forskolin also reduced oocyte and fat areas. In Experiment 3, forskolin negative effect on oocyte maturation and cleavage disappeared, although minor (P<0.03) LD and oocyte fat areas were identified at 22 to 24 h of IVM. Oocytes supplemented with t10,c12 CLA during 44 to 48h presented a lighter (P<0.04) colour tone cytoplasm than those of control and forskolin. In conclusion, t10,c12 CLA and forskolin were capable of modifying the distribution and morphology of cytoplasmic LD during porcine oocyte maturation, thus reducing its lipid content in a time-dependent manner

Can Latin America Move Forward after a Lost Decade in Technical Change? …Looking at Opportunities for Knowledge-based Change in Times of Increasing Uncertainty

In view of the current global context, which challenges are facing science- and technology-based developments and cooperation in a way to contribute for policies that stimulate localized learning, innovation and endogenous development in Latin America? This broad question has motivated the work behind the Special Issue introduced by this paper, which considers the development of case studies in selected Latin America regions. The analysis lead us to argue that value-based networks have the potential to make both public policies and markets more effective, promoting learning trajectories for the inclusive development of regions. But they require effective public investments to keep attracting and qualifying human resources, together with long-term developments towards technical industries and export capacity for emerging markets worldwide. Our analysis argues about the unique potential for further developing Latin America through strategic international, knowledge-based ventures, exploring the emerging role the internationalization of universities and scientific institutions may play at a global level. Above all, they require the systematic observation of science and technical change in international comparison, as well as a relational infrastructure for collective action, at an international level, in a context much influenced by a dynamic of change and a necessary balance between the creation and diffusion of knowledge towards the endogenous development of all parts involved. The role of Latin America Universities and science policies based on international cooperation are considered to be particularly important in this process.published_or_final_versio

AGN behind the SMC selected from radio and X-ray surveys

The XMM-Newton survey of the Small Magellanic Cloud (SMC) revealed 3053 X-ray sources with the majority expected to be active galactic nuclei (AGN) behind the SMC. However, the high stellar density in this field often does not allow assigning unique optical counterparts and hinders source classification. On the other hand, the association of X-ray point sources with radio emission can be used to select background AGN with high confidence, and to constrain other object classes like pulsar wind nebula. To classify X-ray and radio sources, we use clear correlations of X-ray sources found in the XMM-Newton survey with radio-continuum sources detected with ATCA and MOST. Deep radio-continuum images were searched for correlations with X-ray sources of the XMM-Newton SMC-survey point-source catalogue as well as galaxy clusters seen with extended X-ray emission. Eighty eight discrete radio sources were found in common with the X-ray point-source catalogue in addition to six correlations with extended X-ray sources. One source is identified as a Galactic star and eight as galaxies. Eight radio sources likely originate in AGN that are associated with clusters of galaxies seen in X-rays. One source is a PWN candidate. We obtain 43 new candidates for background sources located behind the SMC. A total of 24 X-ray sources show jet-like radio structures.Comment: 9 pages, 6 figures, accepted for publication in A&

Morfologia e reprodução de Mesophyllum erubescens (Foslie) Me. Lemoine (Corallinales, Rhodophyta) do Sul do Brasil

The genus Mesophyllum Me. Lemoine includes around 147 species, of which only three have been referred to the Brazilian coast. Mesophyllum erubescens was originally described from Fernando de Noronha Archipelago, Brazil (type locality). Here we present the first detailed description of M. erubescens based on Brazilian material. Samplings were made through scuba diving at the Biological Marine Reserve of Arvoredo Island, Santa Catarina. The relations of M. erubescens with other similar species, especially from the American Atlantic studied by W.R. Taylor are discussed.O gênero Mesophyllum Me. Lemoine compreende cerca de 147 espécies, das quais apenas três são referidas para a costa brasileira. Mesophyllum erubescens foi originalmente descrita para o Arquipélago de Fernando de Noronha, Brasil (localidade tipo). Neste trabalho é apresentada a primeira descrição detalhada de M. erubescens baseada em material brasileiro. As amostragens foram realizadas através de mergulho autônomo na Reserva Biológica Marinha do Arvoredo, Santa Catarina. As relações de M. erubescens com outras espécies semelhantes são discutidas, sendo especialmente consideradas espécies do Atlântico Americano estudadas por W.R. Taylor

Sensitive areas under radium/uranium mine drainage - the Picoto mine case study, central Portugal

A zona mineira de Picoto está localizada próximo de Vilar Seco (Viseu, Centro de Portugal). Ocorre numa área de declive suave, altitude variando entre 360-380 m, incluída na bacia do rio Cagavaio, com drenagem dominante NE-SW. A mineralização ocorre em veios de quartzo, que intersectam o granito Varisco, porfiróide de duas micas. Os filões de quartzo preenchem falhas N37°-45°E e N50°-70°E, localmente brechificadas. Estes filões contêm meta-torbernite e uranófano, e alguns minerais portadores de U, como clorite e hidróxidos de Fe e Mn. A exploração ocorreu em duas fases, entre 1917 e 1953. Após cessada a exploração, permaneceram as escombreiras resultantes da exploração e a área nunca foi reabilitada. Neste momento, está ocupada por culturas locais, principalmente vinhas e produtos agrícolas. Vinte amostras de águas superficiais e subterrâneas foram colhidas entre 2008 e 2009. Em geral, as águas apresentam valores de pH entre 4.7 a 6.3 e são pouco mineralizadas (CE = 44-190 μS/cm; TDS = 49-137 mg/L). Contudo, algumas águas estão contaminadas em NO2, Fe, Mn, Cu, As e U, e não devem ser utilizadas para consumo humano nem em atividades agrícolas. A contaminação da água está associada principalmente à antiga mina de rádio/urânio e atividades humanas desenvolvidas.The Picoto mine area is located at Vilar Seco village (Viseu, central Portugal), in a soft slope area with altitudes ranging from 360 to 380 m, included in the Cagavaio river catchment, with a dominant NE-SW drainage. The mineralization occurs mainly in quartz veins, which intersect a Variscan porphyritic two-mica granite. The quartz veins fill N37°-45°E and N50°-70°E faults, locally brecciated. The quartz veins contain meta-torbernite and uranophane, and some U-bearing minerals, such as chlorite and Fe- and Mn-hydroxides. The exploitation was carried out in two stages, between 1917 and 1953. Since closure, the area contains mine rejected materials and has never been restored. Therefore, a local cultivated area, mainly for vines and domestic consumption agricultural products, is now deployed. A total of twenty surface and groundwater samples were collected between 2008 and 2009. In general, the waters yield pH values ranging from 4,4 to 6,3 and are poorly mineralized (EC=44-190 µS/cm; TDS= 49-137 mg/L). However, some waters are contaminated with NO₂, Fe, Mn, Cu, As and U and must not be used neither for human consumption nor in agricultural activities. The water contamination is mainly associated with the old radium/uranium mine and subsequent human activities developed in the area.Este trabalho teve suporte financeiro através do ICT e do projeto UID/GEO/04035/2013.info:eu-repo/semantics/publishedVersio

SIMULATION OF THE ALCOHOL-OIL MIXTURE IN A T-SHAPED MICROCHANNEL USING THE DISSIPATIVE PARTICLE DYNAMICS METHOD ON GPU DEVICES

Multiphase fluid motion in microchannnels involves complicated fluid dynamics and is fundamentally important to diverse practical engineering applications. Among several applications, the alcohol-oil mixture is particularly important due to its application for biodiesel production. In this work, the mixture of immiscible fluids alcohol-oil in a square T-shaped microchannel was investigated using the Dissipative Particle Dynamics (DPD) method available in the HOOMD simulator, which runs on a single graphic processing unit (GPU). The immiscible fluids were achieved by increasing the repulsive force between species. The fluid properties and hydrodynamic behavior were discussed in function of model parameters. The simulation results agree with data published in the literature showing that the DPD is appropriate for simulation of mass transport on complex geometries in microscale on a single GPU