634 research outputs found

    Signal Processing

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    Contains reports on one research project.Clarence J. LeBel Fun

    Lean interfaces for integrated catchment management models: rapid development using ICMS

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    A move towards the development of lean, issue-focused interfaces is being explored to provide a rapid delivery mechanism to transfer catchment science to managers and custodians. This approach is a move away from development of large decision support systems which attempt to anticipate a myriad of management questions. It relies on having a modelling system which supports the rapid building and integration of catchment models, and is independent of the interface. ICMS (Interactive Component Modelling System) is a PC-based software tool which has been developed with this in mind. The kernel of the ICMS system, ICMSBuilder, provides the modeller’s view of the world, on top of which can be built any number of interfaces which provide the targetted audience’s view of the world. This paper presents an ICMS prototype to demonstrate the power and flexibility of such an approach. It describes an ICMS project - a suite of linked models which explore the relationships between hydrology, water allocation and extraction rules, and on-farm decision making; and an ICMS View - an interface for that project tailored to address specific management scenarios. Interestingly, the ability to interact with parts of the models through the View gave managers the confidence to delve into the underlying models and data, something often denied to them by traditional decision support systems

    Mobile Market: A Healthy Here Initiative: 2015 Pilot Season Evaluation Report

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    Introduction to Special Issue: Dementia and Music

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    This special issue follows two previous special issues on music and neurological disorders (April 2008, Volume 23/Issue 4 and April 2010, Volume 25/Issue 4). Like its predecessors, the issue presents studies employing a patient-based approach to music perception, cognition, and emotion. Whereas the earlier issues dealt with acquired and congenital disorders and impairments, the present issue focuses on dementia, primarily on its most common form, Alzheimer\u27s disease (AD)

    Healthy Here Mobile Market: improving equitable access to local, organically grown fruits and vegetables.

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    Presented at: 2016 Annual Conference of the New Mexico Public Health Association; April 12-13, 2016; Las Cruces, NM.https://digitalrepository.unm.edu/prc-posters-presentations/1019/thumbnail.jp

    Skeletal Muscle Metabolic Gene Response to Carbohydrate Feeding During Exercise in the Heat

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    Background: Heat stress down-regulates mitochondrial function, while carbohydrate supplementation attenuates the exercise induced stimulation of mitochondrial biogenesis in humans. The effects of exogenous carbohydrate during exercise in the heat on metabolic mRNA have not been investigated in humans. The purpose of this study was to determine the impact of exercise with and without carbohydrate supplementation on skeletal muscle metabolic response in the heat. Methods: Eight recreationally active males (4.05 ± 0.2 L.min-1) completed 2 trials which included 1 hr of cycling at 70% workload max and 3 hr recovery in a hot environment. Both trials were conducted in a climate controlled environmental chamber (38°C and 40% RH). The trials differed by the consumption of either a 6% carbohydrate (CHO) containing beverage (8 ml.kg-1.hr-1) or placebo (P) during exercise in random order. Muscle biopsies were obtained from the vastus lateralis before exercise, immediately post-exercise and at the end of the 3 hr recovery period. Muscle was analyzed for muscle glycogen and mRNA related to metabolic and mitochondrial development (MFN2, PGC-1α, GLUT4, UCP3). Expired gases were measured to determine whole body substrate use during exercise. Results: Carbohydrate oxidation and muscle glycogen utilization did not differ between trials, whereas fat oxidation was elevated during exercise in P. Exercise caused an increase in PGC-1α, and GLUT4 (P \u3c 0.05) independent of exogenous carbohydrate provision. Carbohydrate consumption attenuated the mRNA response in UCP3 (P \u3c 0.05). Conclusions: This study indicates that the provision of exogenous carbohydrate attenuates the stimulation of mRNA expression of UCP3 following exercise in the heat

    Analysis of the Fuel Economy Benefit of Drivetrain Hybridization

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    Parallel- and series-configured hybrid vehicles likely feasible in next decade arc defined and evaluated using NREL's flexible ADvanced VehIcle SimulatOR ADVISOR. Fuel economics of these two diesel-powered hybrid vehicles are compared to a comparable-technology diesel- powered internal-combustion-engine vehicle. Sensitivities of these fuel economies to various vehicle and component parameters are determined and differences among them are explained. The fuel economy of the parallel hybrid defined here is 24% better than the internal- combustion-engine vehicle and 4% better than the series hybrid

    Substrate Use and Biochemical Response to a 3,211-km Bicycle Tour in Trained Cyclists

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    The purpose of this study was to assess the physiological adaptations in physically fit individuals to a period of intensified training. Ten trained males cycled outdoors ~170 km day−1 on 19 out of 21 days. Expired gas was collected on days 1 and 21 during maximal graded exercise and used for the determination of gross efficiency and whole body substrate use. Muscle biopsies were obtained before and after exercise on days 2 and 22 for the determination of mtDNA/gDNA ratio, gene expression, metabolic enzyme activity and glycogen use. Muscle glycogen before and after exercise, fat oxidation, and gross efficiency increased, carbohydrate oxidation decreased (p \u3c 0.05), and VO2max did not change over the 21 days of training. Citrate synthase (CS), β-hydroxyacyl CoA dehydrogenase (β-HAD) and cytochrome c oxidase (COX) enzyme activity did not change with training. CS and β-HAD mRNA did not change with acute exercise or training. COX (subunit IV) mRNA increased with acute exercise (p \u3c 0.05) but did not change over the 21 days. PGC-1α mRNA increased with acute exercise, but did not increase to the same degree on day 22 as it did on day 2 (p \u3c 0.05). UCP3 mRNA decreased with training (p \u3c 0.05). Acute exercise caused an increase in mitofusin2 (MFN2) mRNA (p \u3c 0.05) and a trend for an increase in mtDNA/gDNA ratio (p = 0.057). However, training did not affect MFN2 mRNA or mtDNA/gDNA ratio. In response to 3,211 km of cycling, changes in substrate use and gross efficiency appear to be more profound than mitochondrial adaptations in trained individuals

    Metabolic Profile of the Ironman World Championships: A Case Study

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    Purpose: The purpose of this study was to determine the metabolic profile during the 2006 Ironman World Championship in Kailua-Kona, Hawaii. Methods: One recreational male triathlete completed the race in 10:40:16. Before the race, linear regression models were established from both laboratory and field measures to estimate energy expenditure and substrate utilization. The subject was provided with an oral dose of (2)H(2)(18)O approximately 64 h before the race to calculate total energy expenditure (TEE) and water turnover with the doubly labeled water (DLW) technique. Body weight, blood sodium and hematocrit, and muscle glycogen (via muscle biopsy) were analyzed pre- and postrace. Results: The TEE from DLW and indirect calorimetry was similar: 37.3 MJ (8,926 kcal) and 37.8 MJ (9,029 kcal), respectively. Total body water turnover was 16.6 L. and body weight decreased 5.9 kg. Hematocrit increased from 46 to 51% PCV. Muscle glycogen decreased from 152 to 48 mmoL/kg wet weight pre- to postrace. Conclusion: These data demonstrate the unique physiological demands of the Ironman World Championship and should be considered by athletes and coaches to prepare sufficient nutritional and hydration plans
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