241 research outputs found
MASCC recommendations on the management of constipation in patients with advanced cancer
PURPOSE: The Palliative Care Study Group of the Multinational Association for Supportive Care in Cancer formed a subgroup to develop evidence-based recommendations on the management of constipation in patients with advanced cancer. METHODS: These recommendations were developed in accordance with the MASCC Guidelines Policy. A search strategy for Medline was developed, and the Cochrane Database of Systematic Reviews and the Cochrane Central Register of Controlled Trials were explored for relevant reviews/trials respectively. The recommendations were categorised by the level of evidence and a "category of guideline" based on the level of evidence (i.e. "recommendation", "suggestion", or "no guideline possible"). RESULTS: The group produced 15 recommendations, with varying levels of evidence and so varying categories of guideline. The recommendations relate to the assessment, the treatment, and the re-assessment of constipation. CONCLUSIONS: These recommendations provide a framework for the management of constipation in advanced cancer, although every patient needs individualised management
A 1 m Gas Time Projection Chamber with Optical Readout for Directional Dark Matter Searches: the CYGNO Experiment
The aim of the CYGNO project is the construction and operation of a 1~m
gas TPC for directional dark matter searches and coherent neutrino scattering
measurements, as a prototype toward the 100-1000~m (0.15-1.5 tons) CYGNUS
network of underground experiments. In such a TPC, electrons produced by
dark-matter- or neutrino-induced nuclear recoils will drift toward and will be
multiplied by a three-layer GEM structure, and the light produced in the
avalanche processes will be readout by a sCMOS camera, providing a 2D image of
the event with a resolution of a few hundred micrometers. Photomultipliers will
also provide a simultaneous fast readout of the time profile of the light
production, giving information about the third coordinate and hence allowing a
3D reconstruction of the event, from which the direction of the nuclear recoil
and consequently the direction of the incoming particle can be inferred. Such a
detailed reconstruction of the event topology will also allow a pure and
efficient signal to background discrimination. These two features are the key
to reach and overcome the solar neutrino background that will ultimately limit
non-directional dark matter searches.Comment: 5 page, 7 figures, contribution to the Conference Records of 2018
IEEE NSS/MI
Gas Analysis and Monitoring Systems for the RPC Detector of CMS at LHC
The Resistive Plate Chambers (RPC) detector of the CMS experiment at the LHC
proton collider (CERN, Switzerland) will employ an online gas analysis and
monitoring system of the freon-based gas mixture used. We give an overview of
the CMS RPC gas system, describe the project parameters and first results on
gas-chromatograph analysis. Finally, we report on preliminary results for a set
of monitor RPC.Comment: 9 pages, 8 figures. Presented by Stefano Bianco (Laboratori Nazionali
di Frascati dell'INFN) at the IEEE NSS, San Diego (USA), October 200
Production of H and H with the (K,) reaction
The production of neutron rich -hypernuclei via the
(,) reaction has been studied using data collected with the
FINUDA spectrometer at the DANE -factory (LNF). The analysis of the
inclusive momentum spectra is presented and an upper limit for the
production of H and H from Li and Li, is
assessed for the first time.Comment: 11 pages, 3 figures. Accepted for publication in PL
Correlated pairs from the reaction
Correlated pairs emitted after the absorption of negative kaons
at rest in light nuclei and are
studied. -hyperons and deuterons are found to be preferentially
emitted in opposite directions. The invariant mass spectrum of
shows a bump whose mass is 32516 MeV/c. The bump mass (binding
energy), width and yield are reported. The appearance of a bump is discussed in
the realm of the [] clustering process in nuclei. The experiment was
performed with the FINUDA spectrometer at DANE (LNF).Comment: 13 pages, 5 figures, accepted for publication in Phys. Lett.
A multi-parametric wearable system to monitor neck movements and respiratory frequency of computer workers
Musculoskeletal disorders are the most common form of occupational ill-health. Neck pain is one of the most prevalent musculoskeletal disorders experienced by computer workers. Wrong postural habits and non-compliance of the workstation to ergonomics guidelines are the leading causes of neck pain. These factors may also alter respiratory functions. Health and safety interventions can reduce neck pain and, more generally, the symptoms of musculoskeletal disorders and reduce the consequent economic burden. In this work, a multi-parametric wearable system based on two fiber Bragg grating sensors is proposed for monitoring neck movements and breathing activity of computer workers. The sensing elements were positioned on the neck, in the frontal and sagittal planes, to monitor: (i) flexion-extension and axial rotation repetitions, and (ii) respiratory frequency. In this pilot study, five volunteers were enrolled and performed five repetitions of both flexion-extension and axial rotation, and ten breaths of both quite breathing and tachypnea. Results showed the good performances of the proposed system in monitoring the aforementioned parameters when compared to optical reference systems. The wearable system is able to well-match the trend in time of the neck movements (both flexion-extension and axial rotation) and to estimate mean and breath-by-breath respiratory frequency values with percentage errors ≤6.09% and ≤1.90%, during quiet breathing and tachypnea, respectively
Operational experience with the GEM detector assembly lines for the CMS forward muon upgrade
The CMS Collaboration has been developing large-area triple-gas electron multiplier (GEM) detectors to be installed in the muon Endcap regions of the CMS experiment in 2019 to maintain forward muon trigger and tracking performance at the High-Luminosity upgrade of the Large Hadron Collider (LHC); 10 preproduction detectors were built at CERN to commission the first assembly line and the quality controls (QCs). These were installed in the CMS detector in early 2017 and participated in the 2017 LHC run. The collaboration has prepared several additional assembly and QC lines for distributed mass production of 160 GEM detectors at various sites worldwide. In 2017, these additional production sites have optimized construction techniques and QC procedures and validated them against common specifications by constructing additional preproduction detectors. Using the specific experience from one production site as an example, we discuss how the QCs make use of independent hardware and trained personnel to ensure fast and reliable production. Preliminary results on the construction status of CMS GEM detectors are presented with details of the assembly sites involvement
Performance of a Large-Area GEM Detector Prototype for the Upgrade of the CMS Muon Endcap System
Gas Electron Multiplier (GEM) technology is being considered for the forward
muon upgrade of the CMS experiment in Phase 2 of the CERN LHC. Its first
implementation is planned for the GE1/1 system in the region of the muon endcap mainly to control muon level-1 trigger rates
after the second long LHC shutdown. A GE1/1 triple-GEM detector is read out by
3,072 radial strips with 455 rad pitch arranged in eight -sectors.
We assembled a full-size GE1/1 prototype of 1m length at Florida Tech and
tested it in 20-120 GeV hadron beams at Fermilab using Ar/CO 70:30 and
the RD51 scalable readout system. Four small GEM detectors with 2-D readout and
an average measured azimuthal resolution of 36 rad provided precise
reference tracks. Construction of this largest GEM detector built to-date is
described. Strip cluster parameters, detection efficiency, and spatial
resolution are studied with position and high voltage scans. The plateau
detection efficiency is [97.1 0.2 (stat)]\%. The azimuthal resolution is
found to be [123.5 1.6 (stat)] rad when operating in the center of
the efficiency plateau and using full pulse height information. The resolution
can be slightly improved by 10 rad when correcting for the bias due
to discrete readout strips. The CMS upgrade design calls for readout
electronics with binary hit output. When strip clusters are formed
correspondingly without charge-weighting and with fixed hit thresholds, a
position resolution of [136.8 2.5 stat] rad is measured, consistent
with the expected resolution of strip-pitch/ = 131.3 rad. Other
-sectors of the detector show similar response and performance.Comment: 8 pages, 32 figures, submitted to Proc. 2014 IEEE Nucl. Sci.
Symposium, Seattle, WA, reference adde
A novel application of Fiber Bragg Grating (FBG) sensors in MPGD
We present a novel application of Fiber Bragg Grating (FBG) sensors in the
construction and characterisation of Micro Pattern Gaseous Detector (MPGD),
with particular attention to the realisation of the largest triple (Gas
electron Multiplier) GEM chambers so far operated, the GE1/1 chambers of the
CMS experiment at LHC. The GE1/1 CMS project consists of 144 GEM chambers of
about 0.5 m2 active area each, employing three GEM foils per chamber, to be
installed in the forward region of the CMS endcap during the long shutdown of
LHC in 2108-2019. The large active area of each GE1/1 chamber consists of GEM
foils that are mechanically stretched in order to secure their flatness and the
consequent uniform performance of the GE1/1 chamber across its whole active
surface. So far FBGs have been used in high energy physics mainly as high
precision positioning and re-positioning sensors and as low cost, easy to
mount, low space consuming temperature sensors. FBGs are also commonly used for
very precise strain measurements in material studies. In this work we present a
novel use of FBGs as flatness and mechanical tensioning sensors applied to the
wide GEM foils of the GE1/1 chambers. A network of FBG sensors have been used
to determine the optimal mechanical tension applied and to characterise the
mechanical tension that should be applied to the foils. We discuss the results
of the test done on a full-sized GE1/1 final prototype, the studies done to
fully characterise the GEM material, how this information was used to define a
standard assembly procedure and possible future developments.Comment: 4 pages, 4 figures, presented by Luigi Benussi at MPGD 2015 (Trieste,
Italy). arXiv admin note: text overlap with arXiv:1512.0848
- …