1,639 research outputs found

    Haunting in the historical biopic : Lincoln

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    Lincoln features several key moments in which the conventional, realist coordinates of the historical biopic open to a deeper sense of time and place, evoked in the film's references to clairvoyance, haunting, and ‘bad dreams’ – aspects of Lincoln's interior life that are well known but seldom expressed in film. The theme of haunting in Lincoln is rendered directly, but it is also suggested in the film's multiple references to the medium of photography, and in scenes that recall the flicker effect of early film. The film's complex understanding of time underlines the uncanny nature of the historical biopic, and the strange, almost phantasmatic wish at its core – the wish to impersonate and revivify the dead – a wish that is especially visible in films that take Abraham Lincoln as their subject.PostprintPeer reviewe

    Conjugacy classes in linear groups

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    AbstractLet G belong to one of the three families of complex classical linear groups or to one of the seven families of corresponding real forms. Let L denote its Lie algebra. We give a simple and effective method for finding all conjugacy classes of G and all orbits of G in L. We also describe the splitting of classes and orbits when G is replaced by a normal subgroup. We discuss the situation for other fields

    Posttranslational modifications of alpha-tubulin: acetylated and detyrosinated forms in axons of rat cerebellum.

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    The distribution of acetylated alpha-tubulin in rat cerebellum was examined and compared with that of total alpha-tubulin and tyrosinated alpha-tubulin. From immunoperoxidase-stained vibratome sections of rat cerebellum it was found that acetylated alpha-tubulin, detectable with monoclonal 6-11B-1, was preferentially enriched in axons compared with dendrites. Parallel fiber axons, in particular, were labeled with 6-11B-1 yet unstained by an antibody recognizing tyrosinated alpha-tubulin, indicating that parallel fibers contain alpha-tubulin that is acetylated and detyrosinated. Axonal microtubules are known to be highly stable and the distribution of acetylated alpha-tubulin in other classes of stable microtubules suggests that acetylation and possibly detyrosination may play a role in the maintenance of stable populations of microtubules

    trans-Dichloridobis[dicyclo­hex­yl(phen­yl)phosphane-κP]palladium(II)

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    The title compound, [PdCl2{P(C6H11)2(C6H5)}2], forms a monomeric complex with a trans-square-planar geometry. The Pd—P bond lengths are 2.3343 (5) Å, as the Pd atom lies on an inversion centre, while the Pd—Cl bond lengths are 2.3017 (4) Å. The observed structure was found to be closely related to [PdCl2{P(C6H11)3}2] [Grushin et al. (1994 ▶). Inorg. Chem. 33, 4804–4806], [PdBr2{P(C6H11)3}2] [Clarke et al. (2003 ▶). Dalton Trans. pp. 4393–4394] and [PdCl2P(C6H11)2(C7H7)}2] [Vuoti et al. (2008 ▶). Eur. J. Inorg. Chem. pp. 397–407] (C6H11 is cyclo­hexyl and C7H7 is o-tol­yl). One of the cyclo­hexyl rings is disordered with the phenyl ring in a 0.587 (9):413 (9) ratio. Five long-range C—H⋯Cl inter­actions were observed within the structure

    Learning Timbre Analogies from Unlabelled Data by Multivariate Tree Regression

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    This is the Author's Original Manuscript of an article whose final and definitive form, the Version of Record, has been published in the Journal of New Music Research, November 2011, copyright Taylor & Francis. The published article is available online at http://www.tandfonline.com/10.1080/09298215.2011.596938

    Development, synthesis and anticancer evaluation of trinuclear Platinum Group Metal organometallic complexes

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    Over the past few decades metals in medicine have played to play a significant role, especially after the discovery of the anticancer properties of cisplatin. However, acquired and intrinsic resistance, toxicity and a host of side-effects have encouraged the research for new metal based anticancer agents. Organometallic complexes have proved to be successful anticancer agents and several have commenced clinical trials. The aim of this study was to prepare and characterize trinuclear platinum group organometallic complexes and investigate their in vitro activity. The first series of ester containing complexes were prepared. The ligands were generated by the preparation of Schiff base ligands obtained from the condensation of 4-aminophenylmethanol and either benzaldehyde, 2-pyridinecarboxaldehyde or salicylaldehyde. Trimeric ester ligands were prepared from these monomeric ligands by reaction with trimesoyl chloride

    Triethyl­ammonium hexa-μ2-acetato-κ12 O:O′-diacetato-κ2 O-aqua-μ3-oxido-triferrate(III) toluene monosolvate

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    The title compound, (C6H16N)[Fe3(CH3CO2)8O(H2O)]·C7H8, was serendipitously crystallized from a reaction of disilanol with iron(II) acetate. The trinuclear acetatoferrate(III) anion has a triethyl­ammonium cation as the counterion. The three Fe atoms lie on the vertices of a regular triangle and are octa­hedrally coordinated. The complete coordination of the anion includes shared ligands among the three metal ions: a central tribridging O atom and six bidentate bridging acetyl groups. The six-coordinations of two of the metal ions are completed by a monodentate acetate ligand, whereas that of the third metal ion is completed by a water mol­ecule. The uncoordinated triethyl­ammonium cation is involved in N—H⋯O hydrogen bonding to a singly coordinated acetyl group. The coordinated aqua mol­ecule is involved in bifurcated O—H⋯O hydrogen bonding. C—H⋯O inter­actions are also observed. The toluene solvent molecule is disordered over two sets of sites in a 0.609 (11):0.391 (11) ratio

    Calcium transients in single adrenal chromaffin cells detected with aequorin

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    AbstractThe effect of 55 mM K+ and nicotine on intracellular free calcium was monitored in bovine adrenal chromaffin cells microinjected with aequorin. In contrast to results with quin 2, which suggested that stimulation of chromaffin cells resulted in sustained rises in free calcium, aequorin measurements showed that 55 mM K+ and nicotine resulted in a transient (60–90 s) elevation of free calcium. The peak free calcium and duration of the transient elicited by nicotine were dose-dependent. The concentration of nicotine (10 μM) giving a maximal secretory response gave a peak rise in free calcium of up to 1 μM. 55 mM K+ which only releases 30% of the catecholamine released by 10 μM nicotine generated a calcium transient indistinguishable from that due to 10 μM nicotine. These results support the idea that nicotinic agonists generate an alternative second messenger in addition to the rise in free calcium
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