Lifetime of Excitations in Atomic and Molecular Bose-Einstein Condensates

Recent experimental progress has produced Molecular Superfluids (MSF) in thermal equilibrium; this opens the door to a new class of experiments investigating the associated thermodynamic and dynamical responses. We review the theoretical picture of the phase diagram and quasiparticle spectrum in the Atomic Superfluid (ASF) and MSF phases. We further compute the parametric dependence of the quasiparticle lifetimes at one-loop order. In the MSF phase, the $U(1)$ particle number symmetry breaks to $\mathbb{Z}_2$ and the spectrum exhibits a gapless Goldstone mode in addition to a gapped $\mathbb{Z}_2$-protected atom-like mode. In the ASF phase, the $U(1)$ symmetry breaks completely, leaving behind a Goldstone mode and an unprotected gapped mode. In both phases, the Goldstone mode decays with a rate given by the celebrated Belyaev result, as in a single component condensate. In the MSF phase, the gapped mode is sharp up to a critical Cherenkov momentum beyond which it emits phonons. In the ASF phase, the gapped mode decays with a constant rate even at small momenta. These decay rates govern the spectral response in microtrap tunneling experiments and lead to sharp features in the transmission spectrum of atoms fired through molecular clouds

Tendencia de la electrónica en productos de consumo : oportunidad de innovación para el diseñador industrial

Ponencia en VIII Jornadas de Investigación y II Jornadas de Investigación de Becarios y Doctorandos Encuentro y Reflexión : investigación + transferencia + desarrolloEl siguiente trabajo presenta un estudio que tiene como finalidad, establecer qué relación existe entre el diseño industrial, la electrónica y el un perfil de egresado de la FAUD UNC que pudiera ser demandado en la actualidad. Se busca determinar, si lo hubiera, la oportunidad de innovación que permita el conocimiento, manejo y/o dominio de la electrónica en la carrera de grado de diseño Industrial. La creciente incorporacién de sistemas electrénicos en los productos de consumo destinados al hogar, oficina y/o comercio ha producido un aumentosignificativo de los requerimientos de los mismos en lo quese refiere al consumo racional de energia, facilidad de uso, automatizacién y confort. En consecuencia dichas tendencias constituyen un factor de competitividad en el mercado y en algunos casos son potenciales incorporaciones para superar la obsolescencia del producto. En este contexto corresponde reflexionar sobre el rol del disefo industrial en esta coyuntura contrastada con la formacion del disefador hoy.Fil: Bellitti, Eduardo. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Bellitti, Carlos R. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Villafañez, Blanca Gabriela. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Maurer, Laura Lucía. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Duca, Claudio. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Dovis, Sebastián. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Modesti, Mario. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Da Andrea, Emiliano. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Anastasia, Julio. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Martellotto, Carolina. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Peralta, Agustín A. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; Argentin

Alteration of the translational readthrough isoform AQP4ex induces redistribution and downregulation of AQP4 in human glioblastoma

Glioblastoma multiforme (GBM) is characterized by a remarkable cellular and molecular heterogeneity that make the behavior of this tumor highly variable and resistant to therapy. In addition, the most serious clinical complication of GBM and other brain tumors is the development of vasogenic edema which dramatically increase the intracranial pressure. In the present study we evaluate the expression, supramolecular organization and spatial distribution of AQP4 and AQP4ex, the new readthrough isoform of AQP4, in relationship with the degree of vasogenic brain edema and tumor progression. To this purpose, tissue samples from regions of tumor core, peritumoral and non-infiltrated tissues of each GBM patient (n = 31) were analyzed. Immunofluorescence experiments revealed that the expression of AQP4ex was almost absent in tumoral regions while the canonical AQP4 isoforms appear mostly delocalized. In peritumoral tissues, AQP4 expression was found altered in those perivascular astrocyte processes where AQP4ex appeared reduced and partially delocalized. Protein expression levels measured by immunoblot showed that global AQP4 was reduced mainly in the tumor core. Notably, the relative amount of AQP4ex was more severely reduced starting from the peritumoral region. BN-PAGE experiments showed that the supramolecular organization of AQP4 is only partially affected in GBM. Edema assessment by magnetic resonance imaging revealed that the level of AQP4ex downregulation correlated with edema severity. Finally, the degree of BBB alteration, measured with sodium fluorescein content in GBM biopsies, correlated with the edema index and AQP4ex downregulation. Altogether these data suggest that the AQP4ex isoform is critical in the triggering event of progressive downregulation and mislocalization of AQP4 in GBM, which may affect the integrity of the BBB and contributes to accumulation of edema in the peritumoral tissue. Thus, AQP4ex could be considered as a potential early biomarker of GBM progression

Glut1, glut3 expression and 18fdg-pet/ct in human malignant melanoma: What relationship exists? new insights and perspectives

Background: Malignant melanoma is the most aggressive of skin cancers and the 19th most common cancer worldwide, with an estimated age-standardized incidence rate of 2.8–3.1 per 100,000; although there have been clear advances in therapeutic treatment, the prognosis of MM patients with Breslow thickness greater than 1 mm is still quite poor today. The study of how melanoma cells manage to survive and proliferate by consuming glucose has been partially addressed in the literature, but some rather interesting results are starting to be present. Methods: A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and a search of PubMed and Web of Sciences (WoS) databases was performed until 27 September 2021 using the terms: glucose transporter 1 and 3 and GLUT1/3 in combination with each of the following: melanoma, neoplasm and immunohistochemistry. Results: In total, 46 records were initially identified in the literature search, of which six were duplicates. After screening for eligibility and inclusion criteria, 16 publications were ultimately included. Conclusions: the results discussed regarding the role and expression of GLUT are still far from definitive, but further steps toward understanding and stopping this mechanism have, at least in part, been taken. New studies and new discoveries should lead to further clarification of some aspects since the various mechanisms of glucose uptake by neoplastic cells are not limited to the transporters of the GLUT family alone

Efficacy of weekly docetaxel in locally advanced cardiac angiosarcoma

Background: Primary cardiac angiosarcoma is extremely aggressive; however, it is often misdiagnosed because of its rarity. For locally advanced tumors, doxorubicin-based chemotherapy regimens are the standard of treatment, even if the gain in term of progression-free survival is limited and is no longer than 5 months. Case presentation: We report the case of a Caucasian 23-year-old man with locally advanced cardiac angiosarcoma who underwent radical surgical resection after a prolonged response to weekly docetaxel and complementary radiotherapy. Conclusion: Combined treatment with weekly docetaxel and radiotherapy may be a valid alternative for the treat-ment of locally advanced cardiac angiosarcoma; the combination can lead to radical surgical resections, avoiding the cumulative cardiotoxicity of antracycline-based regimens

Imaging of the Ageing Spine

Purpose of Review: The purpose of this review was to desccribe the main processes related to the ageing spine, studied through different imaging methods. Recent Findings: Degenerative changes in the spine represent a progressive and irreversible involutionary process. They are constantly growing in relation to the increase in the average age of the population; therefore, they constitute an important health problem with enormous socio-economic significance. Summary: The role of the radiologist is fundamental in the evaluation of degenerative processes affecting the bone and intervertebral discs and in the diagnosis of complications