19 research outputs found

    The Political Use of Islamic Variation in Indonesian Islamic Higher Education

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    The Indonesian State Islamic Higher Education (PTAIN) system was created to encourage a progressive form of Islam to oppose political Islam and to be apolitical. Because PTAIN are the official government form of Islamic higher education, PTAIN faculty members can be important opinion makers in the Indonesian Islamic community. PTAIN are critical to understanding the Indonesian Islamic community because they engage in innovative scholarship on Islamic theology, ethics, law, and practice and in the education of young Muslim leaders in many fields. This article explores some of the ways PTAIN have been politicized to play a role in the debates about the future of Indonesian Islam which is developing (or at least showing) more complex variations. It offers a theoretical model for understanding the variation found in Islam

    Human cerebral malaria and Plasmodium falciparum genotypes in Malawi

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    <p>Abstract</p> <p>Background</p> <p>Cerebral malaria, a severe form of <it>Plasmodium falciparum </it>infection, is an important cause of mortality in sub-Saharan African children. A Taqman 24 Single Nucleotide Polymorphisms (SNP) molecular barcode assay was developed for use in laboratory parasites which estimates genotype number and identifies the predominant genotype.</p> <p>Methods</p> <p>The 24 SNP assay was used to determine predominant genotypes in blood and tissues from autopsy and clinical patients with cerebral malaria.</p> <p>Results</p> <p>Single genotypes were shared between the peripheral blood, the brain, and other tissues of cerebral malaria patients, while malaria-infected patients who died of non-malarial causes had mixed genetic signatures in tissues examined. Children with retinopathy-positive cerebral malaria had significantly less complex infections than those without retinopathy (OR = 3.7, 95% CI [1.51-9.10]).The complexity of infections significantly decreased over the malaria season in retinopathy-positive patients compared to retinopathy-negative patients.</p> <p>Conclusions</p> <p>Cerebral malaria patients harbour a single or small set of predominant parasites; patients with incidental parasitaemia sustain infections involving diverse genotypes. Limited diversity in the peripheral blood of cerebral malaria patients and correlation with tissues supports peripheral blood samples as appropriate for genome-wide association studies of parasite determinants of pathogenicity.</p
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