104 research outputs found

    Palichnites et muséologie

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    After they had intrigued the inquiring or observant mind for decades, it was realised that certain "natural curiosities" were tracks of extinct creatures, related to gigantic birds or other antediluvian animals. At the beginning of the XIXth century a new science, ichnology, came into being and developed, thanks to the collection, preservation and study of fossil prints. The increasing quantity of evidence thus unearthed reveals the diversity of vertebrate faunas which have trod the earth’s surface and left behind valuable information about their characteristics and behaviour. Like other institutions labouring on behalf of conservation, knowledge of nature and the preservation of our natural heritage, the Nantes Natural History Museum has, for nearly two centuries, collected, conserved, displayed and brought to the attention of the public those valuable pieces of evidence, fossil footprints. Displays of fossil prints are regularly presented during different exhibitions. Examples of them permit one to follow the evolution of our knowledge of these prints and illustrate how the information yielded by these prints has been transmitted

    CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders

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    Contactin genes CNTN5 and CNTN6 code for neuronal cell adhesion molecules that promote neurite outgrowth in sensory-motor neuronal pathways. Mutations of CNTN5 and CNTN6 have previously been reported in individuals with autism spectrum disorders (ASDs), but very little is known on their prevalence and clinical impact. In this study, we identified CNTN5 and CNTN6 deleterious variants in individuals with ASD. Among the carriers, a girl with ASD and attention-deficit/hyperactivity disorder was carrying five copies of CNTN5. For CNTN6, both deletions (6/1534 ASD vs 1/8936 controls; P=0.00006) and private coding sequence variants (18/501 ASD vs 535/33480 controls; P=0.0005) were enriched in individuals with ASD. Among the rare CNTN6 variants, two deletions were transmitted by fathers diagnosed with ASD, one stop mutation CNTN6W923X was transmitted by a mother to her two sons with ASD and one variant CNTN6P770L was found de novo in a boy with ASD. Clinical investigations of the patients carrying CNTN5 or CNTN6 variants showed that they were hypersensitive to sounds (a condition called hyperacusis) and displayed changes in wave latency within the auditory pathway. These results reinforce the hypothesis of abnormal neuronal connectivity in the pathophysiology of ASD and shed new light on the genes that increase risk for abnormal sensory perception in ASD

    Essai sur la résistance des poteries séchées au soleil et notamment des débris argileux préhistoriques

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    Régnault Félix. Essai sur la résistance des poteries séchées au soleil et notamment des débris argileux préhistoriques. In: Bulletin de la Société préhistorique de France, tome 27, n°9, 1930. pp. 441-443

    Le galop dans l'art paléolithique

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    Régnault Félix. Le galop dans l'art paléolithique. In: Bulletin de la Société préhistorique de France, tome 22, n°4, 1925. p. 158

    Comment représenter les figures préhistoriques ?

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    Régnault Félix. Comment représenter les figures préhistoriques ?. In: Bulletin de la Société préhistorique de France, tome 24, n°7-8, 1927. pp. 291-292

    Les Représentations comparées de la Maternité dans l'art grec et la préhistoire

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    Régnault Félix. Les Représentations comparées de la Maternité dans l'art grec et la préhistoire. In: Bulletin de la Société préhistorique de France, tome 24, n°10, 1927. pp. 374-376

    Prises en main des Outils primitifs dans la Préhistoire et en Australie

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    Régnault Félix. Prises en main des Outils primitifs dans la Préhistoire et en Australie. In: Bulletin de la Société préhistorique de France, tome 35, n°1, 1938. pp. 75-80

    Les soi-disant Sacrifices d'enfants au Temple de Tanit Ă  Carthage

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    Régnault Félix. Les soi-disant Sacrifices d'enfants au Temple de Tanit à Carthage. In: Bulletin de la Société préhistorique de France, tome 26, n°5, 1929. pp. 306-307

    La préhistoire au CongrÚs international d'Anthropologie d'Amsterdam

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    Régnault Félix. La préhistoire au CongrÚs international d'Anthropologie d'Amsterdam. In: Bulletin de la Société préhistorique de France, tome 24, n°11, 1927. pp. 412-413
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