Modeling Emotional Mutation and Evolvement Using Genetic Algorithm in Agency

Human mind has the ability to generate emotions based on internal and external environment. These emotions are based on past experiences and the current situation. Mutation of emotions in human is the change in the intensity of emotion and the more intense the emotion is, it has more chances of existence. In mutative state two emotions are crossover and from the new emotions only the fittest and strongest emotion survive. Emotional mutation and evolvement helps human mind in decision making and in generating response. In agency the phenomenon of emotional modeling can be accomplished by Mutation and Evolvement for generating output. Genetic algorithm is computational model that is inspired by evolution of biological population and by using mutation and crossover of Genetic Algorithm the agency is able to generate output.This paper presents the algorithmic approach for emotional Mutation and Evolvement using Genetic Algorithm for generating output in agency

LI-HE’S MODIFIED HOMOTOPY PERTURBATION METHOD FOR DOUBLY-CLAMPED ELECTRICALLY ACTUATED MICROBEAMS-BASED MICROELECTROMECHANICAL SYSTEM

This paper highlights Li-He’s approach in which the enhanced perturbation method is linked with the parameter expansion technology in order to obtain frequency amplitude formulation of electrically actuated microbeams-based microelectromechanical system (MEMS). The governing equation is a second-order nonlinear ordinary differential equation. The obtained results are compared with the solution achieved numerically by the Runge-Kutta (RK) method that shows the effectiveness of this variation in the homotopy perturbation method (HPM)

Effects Of Phototherapy On Serum Calcium Level In Neonates With Hyperbilirubinemia

Objective: To study the frequency of hypocalcemia in neonates receiving phototherapy with indirect hyperbilirubinemia Materials and Methods: Descriptive case series study was conducted from September 5, 2018, to March 5, 2019, in the NICU of the Paediatric Department Benazir Bhutto Hospital, Rawalpindi. Approval was sought from the hospital’s ethical committee. Neonates fulfilling inclusion criteria were enrolled in the study after obtaining informed consent from the parents. Before giving phototherapy, serum calcium levels were checked. Phototherapy was given for 48 hours. Serum calcium levels were reassessed after 48 hours of phototherapy. Data was entered on a structured proforma and statistical analysis of data was performed. Results: Out of 150 patients enrolled in the study 83(55.33%) were male and 67(44.67%) were female. The mean age of patients was 52.52 hours with minimum and maximum ages of 26 hours and 80 hours. The mean Indirect serum bilirubin level was 15.59 ± 2.36. A total of 50(33.33%) cases had hypocalcemia after 48 hours of phototherapy, all of these neonates had normal calcium levels before phototherapy. When hypocalcaemia was stratified for gestational age, birth weight and serum bilirubin levels at baseline, there was no significant difference in the frequency of hypocalcaemia concerning these effect modifiers. Conclusion: It is concluded that the frequency of hypocalcemia is higher in neonates with indirect hyperbilirubinemia after receiving phototherapy. One needs to be vigilant in dealing with neonates in this context, while serial measurements of calcium levels and monitoring for complications of hypocalcaemia should be included in every institution’s polic

Controllability of Impulsive Neutral Fractional Stochastic Systems

The study of dynamic systems appears in various aspects of dynamical structures such as decomposition, decoupling, observability, and controllability. In the present research, we study the controllability of fractional stochastic systems (FSF) and examine the Poisson jumps in finite dimensional space where the fractional impulsive neutral stochastic system is controllable. Sufficient conditions are demonstrated with the aid of fixed point theory. The Mittag-Leffler (ML) matrix function defines the controllability of the Grammian matrix (GM). The relation to symmetry is clear since the controllability Grammian is a hermitian matrix (since the integrand in its definition is hermitian) and this is the complex version of a symmetric matrix. In fact, such a Grammian becomes a symmetric matrix in the specific scenario where the controllability Grammian is a real matrix. Some examples are provided to demonstrate the feasibility of the present theory.This research is funded by the Basque Government through Grant IT1155-22

MEDICINAL EFFICACY OF ANTIHYPERTENSIVE AGENTS FOR ACUTE INFLAMMATION; AN ASSOCIATED RISK FACTOR OF HYPERTENSION

Hypertension is a lasting therapeutic complaint which can be kept in control by changing one’s dietary and lifestyle habits. Present study is based on identification of risk of acute pancreatitis which may occur with different doses of atenolol in Pakistani population. About 50% of our study population was administered with β-blockers. The β- blockers significantly decreased the levels of CRP (C- Reactive Protein) of test population. This observation strongly depicts high potential of beta blockers in stabilization of CRP levels and decreasing inflammatory response. In our study the patients were administered with many combinations with beta-blocker and their results showed that these combinations lower the CRP level in hypertensive patients. We conclude that antihypertensive also minimize the inflammation associated hypertension but not completely, as inflammation was reversed only in 67.5% population who were using beta-blocker. When treating hypertension, anti-inflammatory medicine treatment needs to be endorsed to successfully treat complaints and increase the communal and psychosomatic status of the patient

Optimal variational iteration method for parametric boundary value problem

Mathematical applications in engineering have a long history. One of the most well-known analytical techniques, the optimal variational iteration method (OVIM), is utilized to construct a quick and accurate algorithm for a special fourth-order ordinary initial value problem. Many researchers have discussed the problem involving a parameter c. We solve the parametric boundary value problem that can't be addressed using conventional analytical methods for greater values of c using a new method and a convergence control parameter h. We achieve a convergent solution no matter how huge c is. For the approximation of the convergence control parameter h, two strategies have been discussed. The advantages of one technique over another have been demonstrated. Optimal variational iteration method can be seen as an effective technique to solve parametric boundary value problem

Comparison of Frequency of Recurrence after Burr Hole Evacuation of Chronic Subdural Hematoma with or without Subdural Drain.

Chronic subdural hematoma (CSDH) is known to have a significant recurrence rate. The rate of recurrence of chronic subdural hematoma after surgery ranges from roughly 5% to 30%.  Burr hole evacuation without drainage is performed as a first line of treatment for CSDH. As there is controversy in literature regarding the use of drainage after burr hole evacuation, the results of my study may be helpful for selecting a proper treatment modality as a first line of treatment for CSDH in terms of recurrence. The objective of this study was to compare the frequency of recurrence after burr hole evacuation of CSDH with and without subdural drain. It was a randomized controlled trial conducted in Department of Neurosurgery, Allied hospital, Faisalabad form Aug 2016 to Aug 2018 RESULTS:In our study, out of 130 cases(65 in each group). 84.62%(n=55) in Group-A and 76.92%(n=50) in Group-B were between above 40 years of age whereas 15.38%(n=10) in Group-A and 23.08%(n=15) were between 18-40 years of age, mean+sd was calculated as  64.03+7.61 years in Group-A and 62.28+7.83 years in Group-B, 78.46%(n=51) in Group-A and 72.31%(n=47) in Group-B were male while 21.54%(n=14) in Group-A and 27.69%(n=18) in Group-B were females, comparison of frequency of recurrence after burr hole evacuation of CSDH with and without subdural drain shows 10.77%(n=7) in Group-A and 27.69%(n=18) in Group-B, p value was 0.01 showing a significant difference. CONCLUSION: We concluded that the frequency of recurrence after burrhole evacuation of CSDH is significantly lower with drain when compared without subdural drain

Comparing Mean Post-Operative Back Pain Score between Hemilaminectomy and Conventional Laminectomy in Patients of Lumbar Stenosis

Objective:  To observe the comparative mean post-operative back-pain score between hemilaminectomy and conventional laminectomy in patients of lumbar stenosis. Material and Methods:  The randomized controlled study was carried out in Neurosurgery Unit, Allied Hospital, Faisalabad, Pakistan. A total of 60 patients were distributed equally in two groups. Group A underwent hemilaminectomy while group B underwent conventional laminectomy. A linear median fascial incision was made on the side with more pain or symptoms. Only in the hemilaminectomy group, ipsilateral decompression was performed. It involves partial resection of adjacent parts of the hemi laminae of the superior and inferior vertebrae using operative loupes or neurosurgical microscope. Mean ±SD was calculated for quantitative data including back pain score. Results:  Mean age was 46.2 ± 6.94 years in hemi group and 46.3 ± 6.74 years in the conventional group. We observed that in hemi group, the back pain score was 2.23 ± 0.73 and it was 2.7 ± 0.65 in the conventional group (p-value was 0.011). Significant differences (p value<0.050) existed in these age ranges with respect to the back pain score in both surgery groups. A significant difference (p value < 0.0001) observed only in male patients between two surgery groups for the back pain scores. Conclusion:  Mean post-operative back pain score is significantly reduced in hemilaminectomy cases when compared with conventional laminectomy in patients of lumbar stenosis

Comparison of Surgical versus Conservative Management of Borderline Traumatic Extradural Hematomas Without Neurological Deficit

Objective:  To compare the outcome of surgical versus conservative treatment of traumatic extradural hematoma in the supratentorial regin. Material and Methods:  It was a prospective randomized controlled trial conducted in Departments of Neurosurgery, Allied Hospitals, Faisalabad between December 2019 to November, 2020. A total of 100 patients Supratentorial EDH; fulfilling the selection criteria were enrolled. All patients underwent clinical and radiological assessment of EDH volume by the same neurosurgical team. The patients were then divided randomly into two groups by using the lottery methods. Group A patients were conservatively managed. Group B underwent surgery. All surgeries were done by the same surgical team. Glasgow outcome scale was noted in 5 days after admission or surgery in both groups. Results:  The patients average age was 29.96 years, male to female ratio was 1.7:1. The mean volume of hematoma was 24.68 and 27.56 in group A (conservative group) and Group B (operated group) respectively. The favorable outcome was noted in all the patients and no mortality occurred in any patients. Conclusion:  Both surgical and conservative treatments are equally effective in terms of a favorable outcome and mortality occurrence in management of traumatic EDH <30ml without neurological deficit. The conservative treatment is safe and cost-effective in borderline patients