33 research outputs found

    The Iowa Homemaker vol.4, no.1

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    Table of Contents The Why of College Training for Motherhood by Lula R. Lancaster, page 3 Does Your Education Stop When You See a French Menu Card? by Katherine Goeppinger, page 4 April Showers by Ada Hayden, page 5 Better Homes by James Ford, page 6 All Is Not Silk That Rustles by Hazel B. McKibben, page 6 Make Your Own Bias Tape by Helen M. Green, page 7 Rejuvenating Our Homes by Lulu Robinson, page 8 Moronitis by H. B. Hawthorn, page 9 Unit Kitchens by Florence Busse, page 10 The Physically Fit Family by Grace Heidbreder, page 11 Early Spring Markets by Marvel Secor, page 11 Who’s There and Where by Dryden Quist, page 12 Editorial, page 13 The Eternal Question, page 14 Homemaker as Citizen, page 15 That Something Different by Rhea Fern Shultz, page 1

    The Iowa Homemaker vol.3, no.12

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    Table of Contents A Greeting to Iowa Homemakers by Dr. Louise Stanley, page 3 A New Book on “Meal Planning and Table Service” by Florence E. Busse, page 4 A Bill of Rights for the Child by Lulu R. Lancaster, page 4 Shrubs as a Garden Background by Juanita Beard, page 5 ‘Tis Egg Time Again by Beth Bailey McLean, page 6 The New Domestic System by Claude L. Benner, page 7 A Time Budget for the Homemaker by Ruth M. Lindquist, page 8 Figures That Do Not Lie by Mae L. Kelley, page 9 The Cooking of Meats by P. Mabel Nelson, page 10 The Psychology of Clothing by Eveleth Pedersen, page 11 Iowa State Women in Rural Schools by W. H. Lancelot, page 12 A Yarn about Yarns by Irene Christian, page 13 Tea Room Accounting by George M. Fuller, page 14 Who’s There and Where by Dryden Quist, page 15 Editorial, page 16 Homemaker as Citizen, page 17 The Eternal Question, page 18 Mrs. Purchaser Chooses Upholstery by Lucile Barta, page 1

    COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

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    Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≀ 18 years: 69, 48, 23; 85%), older adults (≄ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

    Polymorphism: an evaluation of the potential risk to the quality of drug products from the FarmĂĄcia Popular Rede PrĂłpria

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    Crystallization of organic molecules onto functionalized surfaces

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    Crystallization of molecules is a well-known phenomenon and it plays an important role in various industrial domains, including pharmaceutical, yet it remains poorly understood. A particular problem which remains to be solved is the control of polymorphism. We took the approach of surface templated crystallization in order to get an increased understanding of selective polymorph growth processes. Three main parameters were chosen for investigation: the type of interactions between molecules in solution and interfaces, SAM packing and the introduction of a step within the SAM. To that end, a series of crystallization experiments were conducted on three types of interfaces: mono-component, bridged mono-component and bi-component. Introduction of the bridge allowed for modulation of the packing of molecules within the SAMs and insertion of a second component (phenylacetylene) with different backbone and size induced mismatch in interactions as well as formation of a step. Crystallization of two polymorphic model compound, octadecanol and 4-hydroxybiphenyl which present features commonly found in drug molecules, was first studied. Mono-component, bridged mono-component and bi-component SAMs that presented complementary features to the crystallizing molecule were constructed following an acid-base hydrolytic chemistry procedure previously developed in our lab. Characterization of the SAMs was done using ellipsometry, contact angle goniometry, FTIR-ATR and XPS. Presence of complementary features within the SAMs was found to promote crystal growth. For octadecanol, differences in SAM packing and composition were found to greatly influence crystallization outcome. In the case of 4-hydroxybiphenyl, crystallization experiments conducted on a bridged mono-component SAM induced the formation of a new monoclinic polymorph. Principles found in the study of model compounds were then applied to the crystallization of twLa cristallisation des molĂ©cules est un phĂ©nomĂšne trĂšs connu et joue un rĂŽle important dans une grande variĂ©tĂ© de domaines industriels et notamment le domaine pharmaceutique. Ce phĂ©nomĂšne demeure malheureusement fort peu compris. Un point particulier qui reste Ă  Ă©lucider est celui du polymorphisme et surtout de son contrĂŽle. Afin de mieux comprendre les mĂ©canismes de sĂ©lection des polymorphes, nous avons utilisĂ© des surfaces comme patrons lors d'expĂ©riences de cristallisation. Trois paramĂštres furent testĂ©s : l'importance du type d'interactions entre les molĂ©cules en solution et celles de l'interface, l'influence paquetage des monocouches auto-assemblĂ©es ainsi que l'introduction d'une aspĂ©ritĂ© dans la monocouche. Trois types de monocouches furent donc construits : des monocouches mono-composĂ©es, des monocouches mono-composĂ©es pontĂ©es ainsi que des monocouches bi-composĂ©es. L'introduction d'un pont lors de la formation de la monocouche a permis de moduler le paquetage de cette derniĂšre et l'insertion d'un deuxiĂšme composĂ© (le phĂ©nylacĂ©tylĂšne) ne possĂ©dant pas la mĂȘme ossature ni la mĂȘme taille a permis d'induire un dĂ©calage dans les interactions ainsi que d'introduire une aspĂ©ritĂ© Ă  la surface. La cristallisation de deux composĂ©s modĂšles, l'octadĂ©canol et le 4-hydroxybiphenyl, a d'abord Ă©tĂ© rĂ©alisĂ©e. Ces deux composĂ©s ont Ă©tĂ© choisis car ils prĂ©sentent des caractĂ©ristiques frĂ©quemment retrouvĂ©es dans les molĂ©cules pharmaceutiques. Les trois types de monocouches prĂ©sentant des caractĂ©ristiques complĂ©mentaires dĂ©crits prĂ©cĂ©demment ont Ă©tĂ© construits suivant une procĂ©dure impliquant une chimie acido-basique dĂ©veloppĂ©e au sein de notre laboratoire. Ces monocouches ont Ă©tĂ© caractĂ©risĂ©es par ellipsomĂ©trie, par mesure d'angle de contact, par spectroscopie FTIR-ATR et par XPS. Il a Ă©tĂ© observĂ© que la prĂ©sence de caractĂ©ristiques complĂ©me

    Organic Semiconductors Alignment in a Thermal Gradient

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    Organic Semiconductors Alignment in a Thermal Gradient

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    Organic Semiconductors Alignment in a Thermal Gradient

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    Homeotropic and Planar Alignment of Discotic Liquid Crystals: The Role of the Columnar Mesophase

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    Blends of two metal-free phthalocyanine mesogens exhibiting different mesophases (Colr phase from room temperature to isotropization for the first one, and Colr at room temperature then Colh from around 60 °C to isotropization for the second one) have been studied in order to determine the relationship between the type of mesophase and the alignment behavior. The phase diagram of this system has been built and evidence of full solid-state miscibility of the two pure constituents in all proportions and temperatures is presented. Investigation of phase alternation at room temperature as a function of composition revealed that border compositions exhibit Colr phases similar to the pure constituents, whereas Colh mesophase was stabilized for intermediate compositions. Combined polarized optical microscopy observations and X-ray diffraction measurements showed that homeotropic alignment is adopted only for mixed samples exhibiting Colh mesophase, thus demonstrating that the presence of a Colh mesophase is a necessary condition for homeotropic alignment.info:eu-repo/semantics/publishe

    Push-pull chromophores comprising benzothiazolium acceptor and thiophene auxiliary donor moieties: Synthesis, structure, linear and quadratic non-linear optical properties

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    Novel, push-pull chromophores combining a cationic benzothiazolium acceptor moiety and either one or two thiophene rings as a part of the conjugated π-system between the donor and the acceptor moieties have been synthesized and characterized. The chromophores displayed pronounced quadratic NLO activity with their first molecular hyper polarizabilities in agreement with their linear spectral properties. © 2008 Elsevier Ltd. All rights reserved.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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