Opportunities for faculty-librarian collaboration in an expanded dentistry curriculum.

With the increased emphasis on evidence-based practice, developing information literacy (IL), as well as other literacies (e.g., oral), earlier in programs is becoming widely accepted in medicine and allied fields. However with long-standing programs integration of IL instruction is often unplanned at the programmatic level. This contributes to deficiencies in advanced students and frustrations for students and faculty. The Indiana University School of Dentistry has expanded its Dental Hygiene curriculum from a two-year program to a four-year Bachelor of Science. This expansion provided the opportunity to plan integration of information and oral health literacy instruction and evidence-based practice across the new curriculum. Library and Dental Hygiene faculty collaborated to adapt existing undergraduate and oral health pedagogies and assessments, as well as create new ones which are appropriate for integration into various courses. This expanded curriculum integrates lesson plans, assignments, and assessments that support dental hygiene and other health fields but also complement general education and provide transferrable skills for any major. Courses have heavy librarian integration, both in the classroom and the course management software, as well as asynchronous learning tools, with opportunities for team teaching and robust student assessment, including authentic assessment

THE EFFECT OF ANKLE JOINT TAPING ON THE MOTION OF THE ANKLE JOINT DURING TREADMILL RUNNING

Prophylactic ankle taping is frequently used to restrict joint range of motion and prevent further injury. Most studies on this procedure have used quasi-static measures of joint motion and few intervention studies have controlled the exercise load applied to the taped joint. This study examined the effect of protective ankle joint taping on restricting range of motion of the ankle joint using dynamic measures of joint range and controlled exercise intensity. i.e. treadmill running. Eight subjects were video taped whilst running and a moderate speed on a treadmill for 20 minutes. The results indicated that the tape significantly restricted motion in the frontal and sagittal planes. However, after less than 5 minutes exercise the range of motion returned to normal (i.e. untaped motion)

Free energy of adhesion of lipid bilayers on titania surfaces

The adhesion strength between a flexible membrane and a solid substrate (formally the free energy of adhesion per unit area) is difficult to determine experimentally, yet is a key parameter in determining the extent of the wrapping of a particle by the membrane. Here, we present molecular dynamics simulations designed to estimate this quantity between dimyristoylphosphatidylcholine (DMPC) bilayers and a range of low-energy titanium dioxide cleavage planes for both anatase and rutile polymorphs. The average adhesion strength across the cleavage planes for rutile and anatase is relatively weak ∼-2.0 ± 0.4 mN m-1. However, rutile has two surfaces (100 and 101) displaying relatively strong adhesion (-4 mN m-1), while anatase has only one (110). This suggests a slightly greater tendency for bilayers to wrap rutile particles compared to anatase particles but both would wrap less than amorphous silica. We also estimate the adsorption free energies of isolated DMPC lipids and find that only the rutile 101 surface shows significant adsorption. In addition, we estimate the adhesion enthalpies and infer that the entropic contribution to the adhesion free energy drives adhesion on the rutile surfaces and opposes adhesion on the anatase surfaces

Improving First-Year Student Research And Information Literacy Pedagogy By Integrating Librarians

Presented at the 2016 E. C. Moore SymposiumA faculty member and librarian collaborated to adapt a new programmatic IUPUI Bridge/FYS information literacy curriculum to a highly disciplinary, pre-professional course (Dental Hygiene). Development of information literacy instruction that met all the needs of students in the first year experience was only allowable through the close collaboration and multiple levels of library intervention during curriculum scaffolding

Impact of admission screening for methicillin-resistant Staphylococcus aureus on the length of stay in an emergency department.

Preventing and controlling methicillin-resistant Staphylococcus aureus (MRSA) includes early detection and isolation. In the emergency department (ED), such measures have to be balanced with the requirement to treat patients urgently and transfer quickly to an acute hospital bed. We assessed, in a busy and overcrowded ED, the contribution made to a patient\u27s stay by previous MRSA risk group identification and by selective rescreening of those patients who were previously documented in the research hospital as being MRSA positive. Patients with a previous diagnosis of MRSA colonisation were flagged automatically as \u27risk group\u27 (RG) on their arrival in the ED and were compared with \u27non-risk group\u27 (NRG), i.e. not previously demonstrated in the research hospital to be infected or colonised with MRSA. Over an 18 month period, there were 16 456 admissions via the ED, of which 985 (6%) were RG patients. The expected median times to be admitted following a request for a ward bed for NRG and RG patients were 10.4 and 12.9h, respectively. Female sex, age \u3e65 years, and RG status all independently predicted a statistically significantly longer stay in the ED following a request for a hospital bed. We consider that national and local policies for MRSA need to balance the welfare of patients in the ED with the need to comply with best practice, when there are inadequate ED and inpatient isolation facilities. Patients with MRSA requiring emergency admission must have a bed available for them

Nanoparticle–membrane interactions

Engineered nanomaterials have a wide range of applications and as a result, are increasingly present in the environment. While they offer new technological opportunities, there is also the potential for adverse impact, in particular through possible toxicity. In this review, we discuss the current state of the art in the experimental characterisation of nanoparticle-membrane interactions relevant to the prediction of toxicity arising from disruption of biological systems. One key point of discussion is the urgent need for more quantitative studies of nano-bio interactions in experimental models of lipid system that mimic in vivo membranes

Restricted diet in a vulnerable native turtle, Malaclemys terrapin (Schoepff), on the oceanic islands of Bermuda

Diamondback Terrapins (Malaclemys terrapin) are native to Bermuda, presently inhabiting only four small brackish-water ponds. Their foraging ecology was investigated using direct observation, fecal analysis, and necropsy. They do not have as varied a diet as reported from their North American range. Small gastropods (<3 mm shell height) were found in 66.7% of fecal samples and made up 97.3% of animal material dry mass, thus dominating their diet. Scavenged fish and other vertebrates (19% of samples overall), plus terrestrial arthropods (14.3% of samples) were other common items. Polychaete worms and bivalves each occurred in less than 3% of fecal samples. Pond sediment was found in 74% of the samples, probably incidentally ingested while foraging (by oral dredging) for the gastropods. The distribution and abundance of arthropods and molluscs within the terrapins’ brackish-water environment were assessed in three different habitats; pond benthos, mangrove swamp, and grass-dominated marsh. These indicated that Bermuda’s terrapins do not fully exploit the food resources present. On Bermuda M. terrapin is basically a specialist microphagous molluscivore and mainly forages by deposit-feeding on gastropods living in soft sediments. This dietary restriction has made them particularly vulnerable to environmental contamination

Free energy of adhesion of lipid bilayers on silica surfaces

The free energy of adhesion per unit area (hereafter referred to as the adhesion strength) of lipid arrays on surfaces is a key parameter that determines the nature of the interaction between materials and biological systems. Here we report classical molecular simulations of water and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) lipid bilayers at model silica surfaces with a range of silanol densities and structures. We employ a novel technique that enables us to estimate the adhesion strength of supported lipid bilayers in the presence of water. We find that silanols on the silica surface form hydrogen bonds with water molecules and that the water immersion enthalpy for all surfaces varies linearly with the surface density of these hydrogen bonds. The adhesion strength of lipid bilayers is a linear function of the surface density of hydrogen bonds formed between silanols and the lipid molecules on crystalline surfaces. Approximately 20% of isolated silanols form such bonds but more than 99% of mutually interacting geminal silanols do not engage in hydrogen bonding with water. On amorphous silica, the bilayer displays much stronger adhesion than expected from the crystalline surface data. We discuss the implications of these results for nanoparticle toxicity

Equilibrium Simulation of the Slip Coefficient in Nanoscale Pores

Accurate prediction of interfacial slip in nanoscale channels is required by many microfluidic applications. Existing hydrodynamic solutions based on Maxwellian boundary conditions include an empirical parameter that depends on material properties and pore dimensions. This paper presents a derivation of a new expression for the slip coefficient that is not based on the assumptions concerning the details of solid-fluid collisions and whose parameters are obtainable from \textit{equilibrium} simulation. The results for the slip coefficient and flow rates are in good agreement with non-equilibrium molecular dynamics simulation.Comment: 11 pages, 4 figures, submitted to Phys Rev Let