Age and origin of enigmatic megaherbs from the subantarctic islands

Biogeographic relationships in the southern hemisphere have puzzled biologists for the last two centuries. Once joined to form the supercontinent Gondwana, Africa, Antarctica, Australia, New Zealand and South America are widely separated by the Pacific and Indian oceans. Sir Joseph Hooker was the first to suggest that Antarctica served as a corridor for plant migration not unlike the land-bridges in the northern hemisphere. While the Antarctic flora was largely erased by glaciation during the Pleistocene, at least some of these Antarctic plant communities found refuge on the subantarctic islands. Here we provide support for the hypothesis that giant herbs persisted in the subantactic islands prior to the onset of Pleistocene glaciation, then dispersed northward in response to glacial advance. Our findings provide further evidence that Antarctica has played a pivotal role in shaping southern hemisphere biogeography

Self-force via a Green's function decomposition

The gravitational field of a particle of small mass \mu moving through curved spacetime is naturally decomposed into two parts each of which satisfies the perturbed Einstein equations through O(\mu). One part is an inhomogeneous field which, near the particle, looks like the \mu/r field distorted by the local Riemann tensor; it does not depend on the behavior of the source in either the infinite past or future. The other part is a homogeneous field and includes the ``tail term''; it completely determines the self force effects of the particle interacting with its own gravitational field, including radiation reaction. Self force effects for scalar, electromagnetic and gravitational fields are all described in this manner.Comment: PRD, in press. Enhanced emphasis on the equivalence principl

Crowding-induced hybridization of single DNA hairpins

It is clear that a crowded environment influences the structure, dynamics, and interactions of biological molecules, but the complexity of this phenomenon demands the development of new experimental and theoretical approaches. Here we use two complementary single-molecule FRET techniques to show that the kinetics of DNA base pairing and unpairing, which are fundamental to both the biological role of DNA and its technological applications, are strongly modulated by a crowded environment. We directly observed single DNA hairpins, which are excellent model systems for studying hybridization, either freely diffusing in solution or immobilized on a surface under crowding conditions. The hairpins followed two-state folding dynamics with a closing rate increasing by 4-fold and the opening rate decreasing 2-fold, for only modest concentrations of crowder [10% (w/w) polyethylene glycol (PEG)]. These experiments serve both to unambiguously highlight the impact of a crowded environment on a fundamental biological process, DNA base pairing, and to illustrate the benefits of single-molecule approaches to probing the structure and dynamics of complex biomolecular systems

Proposing a Metacurriculum for Occupational Therapy Education in 2025 and Beyond

The American healthcare system has undergone significant changes in the past few years due to government and corporate-level changes. As healthcare requirements continue to shift, occupational therapists must continue to assert their role or risk losing relevancy. Therefore, educational programs must prepare students to meet the populations’ shifting healthcare needs through agile curricula which focus less on isolated skills and more on broad areas of impact. To determine essential content comprising a ‘metacurriculum’ for occupational therapy education of the future, nine articles were analyzed using Bloom’s Taxonomy (revised) to code each document into knowledge, skills, and behaviors. Major themes were identified across all documents. Through the coding analysis eleven themes were identified: population health, developing life-long learners, advocacy (at government and individual level), interprofessional collaboration, generation of evidence and translational science, diversity and inclusion, psychosocial concerns, aging, wellbeing and preventative care, contemporary issues and informatics. The themes can serve as an outline for academic programs to continue to evolve their curricula to ensure that practitioners are fully prepared to address the global issues that will manifest during their careers in occupational therapy

Mangrove system dynamics in Southeast Asia: linking livelihoods and ecosystem services in Vietnam

Across Southeast Asia, human activity has caused rapid mangrove system degradation and loss. In Vietnam, a country undergoing economic transition, mangrove systems are vital to the livelihoods of coastal rural communities. This paper studies three mangrove system-dependent communities on Vietnam’s northern coast. Guided by the sustainable livelihood framework, the paper adopts a mixed methods approach. It presents current uses of mangrove system goods and the factors shaping past livelihood responses to mangrove system change, using livelihood trajectory analysis. Findings demonstrate that communities depend on mangrove systems to different degrees for income, subsistence and to respond to change. However, the rapid development of aquaculture is associated with a significantly reduced and degraded mangrove system commons necessary to support the livelihoods of low-income households. Three distinct livelihood trajectories are identified: consolidator groups able to use their access to a wide range of resources, locked into resilient trajectories; accumulator groups able to use their access to limited resources to move from vulnerable to more resilient trajectories; and marginalised groups facing increasingly reduced access to resources locked into vulnerable trajectories. Vietnam faces challenges in reconciling a more market-orientated economy with the maintenance of mangrove system functions and processes that shape the vulnerability and resilience of livelihood trajectories. Policies and projects promoting the sustainable management of mangrove systems should acknowledge the substantial contribution and multiple uses of mangrove systems in livelihoods, particularly of the poor, and the impact of aquaculture on income equality and livelihood diversity that shapes household resilience and vulnerability

Correlation of Crystal Quality and Extreme Magnetoresistance of WTe2_2

High quality single crystals of WTe$_2$ were grown using a Te flux followed by a cleaning step involving self-vapor transport. The method is reproducible and yields consistently higher quality single crystals than are typically obtained via halide assisted vapor transport methods. Magnetoresistance (MR)values at 9 Tesla and 2 Kelvin as high as 1.75 million \%, nearly an order of magnitude higher than previously reported for this material, were obtained on crystals with residual resistivity ratio (RRR) of approximately 1250. The MR follows a near B$^2$ law (B = 1.95(1)) and, assuming a semiclassical model, the average carrier mobility for the highest quality crystal was found to be ~167,000 cm$^2$/Vs at 2 K. A correlation of RRR, MR ratio and average carrier mobility ($\mu_{avg}$) is found with the cooling rate during the flux growth.Comment: 7 pages, 3 figures, 1 tabl

Recovery from disturbance requires resynchronization of ecosystem nutrient cycles

Nitrogen (N) and phosphorus (P) are tightly cycled in most terrestrial ecosystems, with plant uptake more than 10 times higher than the rate of supply from deposition and weathering. This near-total dependence on recycled nutrients and the stoichiometric constraints on resource use by plants and microbes mean that the two cycles have to be synchronized such that the ratio of N:P in plant uptake, litterfall, and net mineralization are nearly the same. Disturbance can disrupt this synchronization if there is a disproportionate loss of one nutrient relative to the other. We model the resynchronization of N and P cycles following harvest of a northern hardwood forest. In our simulations, nutrient loss in the harvest is small relative to postharvest losses. The low N:P ratio of harvest residue results in a preferential release of P and retention of N. The P release is in excess of plant requirements and P is lost from the active ecosystem cycle through secondary mineral formation and leaching early in succession. Because external P inputs are small, the resynchronization of the N and P cycles later in succession is achieved by a commensurate loss of N. Through succession, the ecosystem undergoes alternating periods of N limitation, then P limitation, and eventually co-limitation as the two cycles resynchronize. However, our simulations indicate that the overall rate and extent of recovery is limited by P unless a mechanism exists either to prevent the P loss early in succession (e.g., P sequestration not stoichiometrically constrained by N) or to increase the P supply to the ecosystem later in succession (e.g., biologically enhanced weathering). Our model provides a heuristic perspective from which to assess the resynchronization among tightly cycled nutrients and the effect of that resynchronization on recovery of ecosystems from disturbance

Extraction and Quantification of Sinapinic Acid from Irish Rapeseed Meal and Assessment of Angiotensin-I Converting Enzyme (ACE-I) Inhibitory Activity

Phenolic compounds, including phenolic acids, are known to play a protective role against the development of cardiovascular disease. The aim of this work was to generate a phenolic acid extract from Irish rapeseed meal, to determine the quantity of sinapinic acid (SA) in this fraction and to assess the ability of this fraction to inhibit the enzyme angiotensin-I converting enzyme (ACE-I; EC 3.4.15.1). A crude phenolic extract (fraction 1), free phenolic acid containing extract (fraction 2), and an extract containing phenolic acids liberated from esters (fraction 3) were generated from Irish rapeseed meal using a methanol:acetone:water solvent mixture (7:7:6). The total phenolic content (TPC) of each extract was determined and proximate analysis performed to determine the fat, moisture, and protein content of these extracts. Nuclear magnetic resonance (1H NMR) spectroscopy was used to quantify the level of SA in extract 3, which inhibited ACE-I by 91% ± 0.08 when assayed at a concentration of 1 mg/mL, compared to the control, captopril, which inhibited ACE by 97% ± 0.01 when assayed at a concentration of 1 mg/mL

Surface Charge Control of Quantum Dot Blinking

A characteristic property of colloidal semiconductor nanocrystal quantum dots (QDs) is their emission intermittency. Although a unifying theory of QD photoprocesses remains elusive, the importance of charged states is clear. We now report a new approach to directly study the role of surface charge on QD emission by adding metal ions to individual, core-only QDs immobilized in aqueous solution in an agarose gel. The CdTe QDs show very stable emission in the absence of metal ions but a dramatic and reversible increase in blinking due to the presence of trivalent metal ions. Our results support a charge-separation model, in which the major blinking pathway is the surface trapping of electrons; transiently bound metal ions close to the QD surface enhance this process