14 research outputs found
Kyste neurentĂ©rique intra dural extra mĂ©dullaire: Ă propos dâun cas
Le kyste neurentĂ©rique (KNE) est une malformation congĂ©nitale rare du systĂšme nerveux central (SNC) entrant dans le cadre des notochordodysraphies. Nous rapportons un nouveau cas de KNE de localisation intra durale extra mĂ©dullaire chez un patient de 16 ans, admis dans un tableau de compression mĂ©dullaire cervicale haut Ă©voluant depuis 4 mois. Lâimagerie a objectivĂ© une lĂ©sion kystique prĂ© mĂ©dullaire en regardde C1-C2-C3. Le patient a bĂ©nĂ©ficiĂ© dâune Ă©vacuation kystique et lâhistologie avait conclu Ă un kyste neurentĂ©rique. LâĂ©volution Ă©tait marquĂ©e par le dĂ©cĂšs du patient par des complications neurovĂ©gĂ©tatives graves. MalgrĂ© sa bĂ©nignitĂ© histologique, le kyste neurentĂ©rique de localisation cervicale haute peut se compliquer de troubles neurovĂ©gĂ©tatifs parfois imprĂ©visibles pouvant aboutir Ă une Ă©volution dramatique
Traitement peu invasif dâune breche osteo meningee associee a une hypertension intracranienne benigne
Description Lâhypertension intracrĂąnienne bĂ©nigne (HTICB) est une augmentation anormale de la pression intracrĂąnienne non associĂ©e Ă un processus occupant de lâespace intracrĂąnien, une thrombose des veinescĂ©rĂ©brales ou une hydrocĂ©phalie. CaractĂ©risĂ©e par des cĂ©phalĂ©es invalidantes, des acouphĂšnes pulsatiles, elle peut avoir une Ă©volution pĂ©jorative et irrĂ©versible entraĂźnant une cĂ©citĂ©. La survenue dâune rhinorrhĂ©e spontanĂ©e dans un contexte dâHTICB a Ă©tĂ© dĂ©crite dans la littĂ©rature mais demeure peu frĂ©quente. Objectif et cas cliniqueNous rapportons le cas dâune femme obĂšse ĂągĂ©e de 40 ans, qui a Ă©tĂ© admise pour rhinorrhĂ©e droite spontanĂ©e. Les explorations neuroradiologiques ont permis dâĂ©voquer une hypertension intracrĂąnienne bĂ©nigne sur une brĂšche ethmoĂŻdale antĂ©rieure. Le monitoring de la pression a confirmĂ© le diagnostic. Elle abĂ©nĂ©ficiĂ© dâune dĂ©rivation ventriculo pĂ©ritonĂ©ale. LâĂ©volution est favorable (disparition des symptĂŽmes) avec un delai de recul de 16 mois . Conclusion LâHTICB est une pathologie avec des consĂ©quences irrĂ©versibles si le traitement nâest pas adĂ©quat et rapide. En cas de rhinorrhĂ©e isolĂ©e dans le cadre de lâhypertension intracrĂąnienne bĂ©nigne la dĂ©rivation ventriculo pĂ©ritonĂ©ale est une attitude thĂ©rapeutique simple mais efficace
Classification of large-scale environments that drive the formation of mesoscale convective systems over southern West Africa
Mesoscale convective systems (MCSs) are frequently observed over southern West Africa (SWA) throughout most of the year. These MCS events are the dominant rain-bearing systems, contributing over 50â% of annual rainfall over SWA. However, it has not yet been identified what variations in typical large-scale environments of the seasonal cycle of the West African monsoon may favour MCS occurrence in this region. Here, nine distinct synoptic states are identified and are further associated with being a synoptic-circulation type of either
a dry, transition, or monsoon season using self-organizing maps (SOMs) with inputs from reanalysis data. We identified a
pronounced annual cycle of MCS numbers with frequency peaks in April and
October that can be associated with the start of rainfall during the major
rainy season and the maximum rainfall for the minor rainy season across SWA,
respectively. Comparing daily MCS frequencies, MCSs are most likely to
develop during transition conditions featuring a northward-displaced
moisture anomaly (2.8Â MCSs per day), which can be linked to strengthened
low-level westerlies. Considering that these transition conditions occur
predominantly during the pre- and post-monsoon period, these patterns may in
some cases be representative of monsoon onset conditions or a delayed
monsoon retreat. On the other hand, under monsoon conditions, we observe
weakened low-level south-westerlies during MCS days, which reduce moisture
content over the Sahel but introduce more moisture over the coast. Finally,
we find a majority of MCS-day synoptic states exhibiting positive zonal wind
shear anomalies. Seasons with the strongest zonal wind shear anomalies are
associated with the strongest low-level temperature anomalies to the north
of SWA, highlighting that a warmer Sahel can promote MCS-favourable
conditions in SWA. Overall, the SOM-identified synoptic states converge
towards high-moisture and high-shear conditions on MCS days in SWA, where
the frequency at which these conditions occur depends on the synoptic state.</p
A community-based lifestyle and weight loss intervention promoting a Mediterranean-style diet pattern evaluated in the stroke belt of North Carolina: the Heart Healthy Lenoir Project
Abstract
Background
Because residents of the southeastern United States experience disproportionally high rates of cardiovascular disease (CVD), it is important to develop effective lifestyle interventions for this population.
Methods
The primary objective was to develop and evaluate a dietary, physical activity (PA) and weight loss intervention for residents of the southeastern US. The intervention, given in eastern North Carolina, was evaluated in a 2Ă year prospective cohort study with an embedded randomized controlled trial (RCT) of a weight loss maintenance intervention. The intervention included: Phase I (months 1ĂąâŹâ6), individually-tailored intervention promoting a Mediterranean-style dietary pattern and increased walking; Phase II (months 7ĂąâŹâ12), option of a 16-week weight loss intervention for those with BMIĂąâŹâ°Ăąâ°Â„ĂąâŹâ°25Ă kg/m2 offered in 2 formats (16 weekly group sessions or 5 group sessions and 10 phone calls) or a lifestyle maintenance intervention; and Phase III (months 13ĂąâŹâ24), weight loss maintenance RCT for those losingĂąâŹâ°Ăąâ°Â„ĂąâŹâ°8 lb with all other participants receiving a lifestyle maintenance intervention. Change in diet and PA behaviors, CVD risk factors, and weight were assessed at 6, 12, and 24Ă month follow-up.
Results
Baseline characteristics (NĂąâŹâ°=ĂąâŹâ°339) were: 260 (77Ă %) females, 219 (65Ă %) African Americans, mean age 56Ă years, and mean body mass index 36Ă kg/m2. In Phase I, among 251 (74Ă %) that returned for 6Ă month follow-up, there were substantial improvements in diet score (4.3 units [95Ă % CI 3.7 to 5.0]), walking (64Ă min/week [19 to 109]), and systolic blood pressure (ĂąËâ6.4Ă mmHg [ĂąËâ8.7 to ĂąËâ4.1]) that were generally maintained through 24Ă month follow-up. In Phase II, 138 (57 group only, 81 group/phone) chose the weight loss intervention and at 12Ă months, weight change was: ĂąËâ3.1Ă kg (ĂąËâ4.9 to ĂąËâ1.3) for group (NĂąâŹâ°=ĂąâŹâ°50) and ĂąËâ2.1Ă kg (ĂąËâ3.2 to ĂąËâ1.0) for group/phone combination (NĂąâŹâ°=ĂąâŹâ°75). In Phase III, 27 participants took part in the RCT. At 24Ă months, weight loss was ĂąËâ2.1Ă kg (ĂąËâ4.3 to 0.0) for group (NĂąâŹâ°=ĂąâŹâ°51) and ĂąËâ1.1Ă kg (ĂąËâ2.7 to 0.4) for combination (NĂąâŹâ°=ĂąâŹâ°72). Outcomes for African American and whites were similar.
Conclusions
The intervention yielded substantial improvement in diet, PA, and blood pressure, but weight loss was modest.
Trial registration
clinicaltrials.gov Identifier:
NCT0143348
A Rare Case of Adult Medulloblastoma with Spinal Metastasis
Medulloblastoma is a relatively common malignant brain tumor of childhood and relatively rare in adulthood, with a propensity for neuraxial spread via cerebrospinal fluid pathways. Osseous extraneural metastasis is uncommon and when it happens, radiologic findings are of sclerotic (60%), lytic (35%), and mixed patterns (5%) (Algra et al. (1992)). In this paper, we present a case of medulloblastoma metastiaszing to the lumbar spine and describe the magnetic resonance appearance, with emphasis on the image findings mimicking spondylodiscitis
The Grand Popo experiment, Benin
International audienceThe first large nearshore field experiment in the G ulf of Guinea was conducted at Grand Popo Beach, Be nin, in February 2013, on an open wave-dominated micro- to meso-tidal coast, located mid-way between Cotonou and Lome harbours. The overall project aims at understanding at multi-scale (from event to interannual) the causes of the dramatic erosion observed throughout the Bight of Benin, and caused by the interaction of a large littoral drift with human engineering works. Grand Popo 2013 experiment was designed to measure the processes over the short term and to test the ability of an installed video system to monitor the evolution of this stretch of coast over the longer term. The beach, characterized by a low-tide terrace and a high tide reflective part, experiences a long swell (Hs=1.6m, Tp=16 s, oblique incidence ~15-20°). Topographic surveys showed a double beach cusp system interaction and repeated surf-zone drifter runs revealed high flash and swash rip activity driven by wave dissipation over the terrace and energetic swash dynamics at the upper reflective beach. Swash was measured over a cusp system at two locations using video poles. Wave reanalyses (ERAInterim) were used to determine the wave climate and its variability, and to quantify sediment transport. This robust methodology is thought to be replicated elsewhere in different coastal environments in West Africa, in particular with the objective to monitor various sites within the framework of the new West African Coastal Observatory
The Grand Popo beach 2013 experiment, Benin, West Africa: from short timescale processes to their integrated impact over long-term coastal evolution
The first large nearshore field experiment in the Gulf of Guinea was conducted at Grand Popo Beach, Benin, in February 2013, on an open wave-dominated micro- to meso-tidal coast, located mid-way between Cotonou and Lome harbours. The overall project aims at understanding at multi-scale (from event to interannual) the causes of the dramatic erosion observed throughout the Bight of Benin, and caused by the interaction of a large littoral drift with human engineering works. Grand Popo 2013 experiment was designed to measure the processes over the short term and to test the ability of an installed video system to monitor the evolution of this stretch of coast over the longer tenn. The beach, characterized by a low-tide terrace and a high tide reflective part, experiences a long swell (Hs=1.6 m, Tp=16 s, oblique incidence similar to 15-20 degrees). Topographic surveys showed a double beach cusp system interaction and repeated surf-zone drifter runs revealed high flash and swash rip activity driven by wave dissipation over the terrace and energetic swash dynamics at the upper reflective beach. Swash was measured over a cusp system at two locations using video poles. Wave reanalyses (ERAInterim) were used to determine the wave climate and its variability, and to quantify sediment transport. This robust methodology is thought to be replicated elsewhere in different coastal environments in West Africa, in particular with the objective to monitor various sites within the framework of the new West African Coastal Observatory